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公开(公告)号：US20030199790A1
公开(公告)日：2003-10-23
申请号：US10335182
申请日：2002-12-31
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B005/00 , B65D081/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A skin penetrating system includes a housing member and a penetrating member positioned in the housing member. An analyte detecting member is coupled to a sample chamber. The analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 nullL of a body fluid disposed in the sample chamber. A tip of the penetrating member is configured to extend through an opening of the sample chamber.
摘要翻译： 皮肤穿透系统包括壳体构件和定位在壳体构件中的穿透构件。 分析物检测部件耦合到样品室。 分析物检测构件被配置为使用设置在样品室中的体积小于1μl的样品来确定体液中的分析物的浓度。 穿透构件的尖端构造成延伸穿过样品室的开口。
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公开(公告)号：US08211037B2
公开(公告)日：2012-07-03
申请号：US11317659
申请日：2005-12-22
申请人： Dominique Freeman , Dirk Boecker , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
发明人： Dominique Freeman , Dirk Boecker , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
IPC分类号： A61B5/00
CPC分类号： A61M5/46 , A61B5/14532 , A61B5/150022 , A61B5/150061 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M5/158 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502746 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905 , G01N33/557 , G06F19/00
摘要： A system is provided that controls movement of a lancet. One or more processors execute program instructions and receive a data set. The program instructions are executed to cause the processor to, cause force to be applied to the lancet to thereby cause the lancet to move in a first direction toward a target, monitor position and speed of the lancet as the lancet moves in the first direction, adjust the application of force to the lancet as the lancet moves in the first direction to achieve a desired speed of the lancet, and adjust the application of force to the lancet when the lancet contacts the target so that the lancet penetrates the target within a desired range of speed.
摘要翻译： 提供了一种控制柳叶刀运动的系统。 一个或多个处理器执行程序指令并接收数据集。 执行程序指令以使处理器对刺血针施加力，从而使柳叶刀沿着朝向目标的第一方向移动，当柳叶刀沿第一方向移动时监视刺血针的位置和速度， 当柳叶刀沿第一方向移动时，调整对柳叶刀的施加力，以达到刺血针的期望速度，并且当柳叶刀接触靶时调整对柳叶刀的施加力，使得刺血针在期望的范围内穿透靶 速度范围
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公开(公告)号：US08062231B2
公开(公告)日：2011-11-22
申请号：US11548533
申请日：2006-10-11
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. The drive force generator is configured to be controlled to follow a predetermined velocity trajectory into the tissue and out of the tissue. A tissue stabilizing member is associated with the device and at least partially surrounds an impact location of the penetrating member on the tissue site.
摘要翻译： 本发明的这些和其它目的在体液采集系统中实现，该体液采样系统用于组织部位，其包括驱动力发生器和可操作地联接到力发生器的穿透构件。 力产生器沿着路径将构件沿着穿过构件出口的壳体移动到组织部位中，停止在组织部位中，并从组织部位抽出。 驱动力发生器被配置为被控制以遵循预定的速度轨迹进入组织并离开组织。 组织稳定构件与装置相关联并且至少部分地围绕穿刺构件在组织部位上的冲击位置。
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公开(公告)号：US08016774B2
公开(公告)日：2011-09-13
申请号：US11317912
申请日：2005-12-22
申请人： Dominique Freeman , Dirk Boecker , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
发明人： Dominique Freeman , Dirk Boecker , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
IPC分类号： A61B5/00
CPC分类号： A61M5/46 , A61B5/14532 , A61B5/150022 , A61B5/150061 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M5/158 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502746 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905 , G01N33/557 , G06F19/00
摘要： An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft.
摘要翻译： 提供了能够将药剂注射到已知的预定组织深度的药剂注射装置。 注射构件具有细长注射轴，其具有配置成在可控制时间分配药剂的出口端口。 可控制的驱动器联接到细长注射轴并被构造成将注射构件驱动到靶组织中。 速度控制系统与可控驱动器连通，并被配置成控制细长注射轴的速度。
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45.发明授权公开(公告)号：US07988644B2
公开(公告)日：2011-08-02
申请号：US11688927
申请日：2007-03-21
申请人： Dominique Freeman , Don Alden , Dirk Boecker , Michael Cane , Matt Schumann , Michael Beadman
发明人： Dominique Freeman , Don Alden , Dirk Boecker , Michael Cane , Matt Schumann , Michael Beadman
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： A device for use with a gripper is provided. A cartridge is provided that defines a plurality of cavities. A plurality of penetrating members are at least partially contained in the cavities of the cartridge. The penetrating members are slidably movable to extend outward from the cartridge to penetrate tissue. Each cavity has a longitudinal opening that provides access to an elongate portion of the penetrating member. A sterility barrier is coupled to the cartridge. The sterility barrier covers a plurality of the longitudinal openings. The sterility barrier is configured to be moved so that the elongate portion is accessed by the gripper without touching the barrier.
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公开(公告)号：US07981055B2
公开(公告)日：2011-07-19
申请号：US11318247
申请日：2005-12-22
申请人： Dominique Freeman , Dirk Boecher , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
发明人： Dominique Freeman , Dirk Boecher , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
IPC分类号： A61B5/00
CPC分类号： A61M5/46 , A61B5/14532 , A61B5/150022 , A61B5/150061 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M5/158 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L3/502746 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905 , G01N33/557 , G06F19/00
摘要： A sampling module includes a module body portion with a lancet channel, a lancet slidably disposed within the lancet channel. A cover sheet is disposed over the lancet and a lancet channel that captures the lancet shaft in the lancet channel, and a sample reservoir for collection of a sample obtained by lancing a patient with the lancet.
摘要翻译： 采样模块包括具有刺血针通道的模块主体部分，可滑动地设置在刺血针通道内的刺血针。 覆盖片设置在刺血针上方，并且刺血针通道捕获刺血针通道中的刺血针轴，以及样品容器，用于收集通过将患者与刺血针进行穿刺而获得的样品。
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公开(公告)号：US07959582B2
公开(公告)日：2011-06-14
申请号：US11689375
申请日：2007-03-21
申请人： Dominique Freeman , Dirk Boecker , Don Alden
发明人： Dominique Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
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公开(公告)号：US07833171B2
公开(公告)日：2010-11-16
申请号：US11674191
申请日：2007-02-13
申请人： Dominique Freeman , Dirk Boecker , Don Alden
发明人： Dominique Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 墨盒容纳穿透构件。 筒具有联接到穿透构件的第一和第二密封件，以在穿透构件致动之前保持穿透构件的一部分周围的无菌环境。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。
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公开(公告)号：US07717863B2
公开(公告)日：2010-05-18
申请号：US10335240
申请日：2002-12-31
申请人： Dominique M. Freeman , Don Alden , Dirk Boecker
发明人： Dominique M. Freeman , Don Alden , Dirk Boecker
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetration device includes a penetrating member driver and a cartridge. A plurality of penetrating members are integrated with the cartridge. Each penetrating member is coupled to the penetrating member driver when advanced along a path into a tissue target. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
摘要翻译： 组织穿透装置包括穿透构件驱动器和盒。 多个穿透构件与盒一体化。 当沿着进入组织靶的路径前进时，每个穿透构件联接到穿透构件驱动器。 穿透构件传感器联接到多个穿透构件。 穿透构件传感器被配置为提供关于穿透构件穿过皮肤表面的穿透深度的信息。
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公开(公告)号：US07481776B2
公开(公告)日：2009-01-27
申请号：US10335259
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
CPC分类号： A61B5/15178 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905 , G01N33/557
摘要： A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber. The sample chambers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
摘要翻译： 皮肤穿透系统设置有驱动力发生器和一次性外壳构件。 多个穿透构件定位在一次性外壳构件中。 每个穿透构件联接到驱动力发生器。 多个分析物检测构件各自与穿透构件相关联并且被定位在一次性外壳构件中。 每个分析物检测构件定位在样品室中。 样品室具有用于将体液输送到样品室中的开口。 每个分析物检测构件被配置成确定体液中分析物的浓度。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。
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