公开(公告)号：US20240207047A1

公开(公告)日：2024-06-27

申请号：US18556552

申请日：2021-08-20

Applicant: SHANGHAI TRULIVE MEDTECH CO., LTD. ,  JIANGSU TRULIVE MEDTECH CO., LTD.

Inventor： Wei YANG ,  Jing WEN

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0008

Abstract: A valve prosthesis includes a stent (10) and a skirt assembly. The stent (10) has an inflow end (11) and an outflow end (12) opposite to the inflow end along an axial direction of the stent. The skirt assembly includes at least two skirts (20) surrounding the stent (20) in the shape of rings and each having an inner edge (21) and an outer edge (22). The inner edge (21) is an edge of the skirt (20) closer to an axis of the stent (10), and the outer edge (22) is an edge of the skirt (20) farther away from the axis of the stent (10). The inner edge (21) is attached to the stent (10), and the outer edge (22) forms a free end. The at least two skirts (20) are arranged with a spacing along the axial direction of the stent (10) and have different radial outer dimensions, and at least one of the skirts (20) is configured to be brought into contact at its outer edge (22) with native tissue (50). With this configuration, even when a small amount of blood enters a gap between the skirts (20) and the native tissue (50), it will be blocked by the skirts (20) with different radial outer dimensions, resulting in the formation of a slow blood flow region. In this region, blood can more easily coagulate, reducing paravalvular leakage and accelerating endothelialization. Moreover, the radial outer dimensions of the skirts (20) vary which roughens the skirt assembly, facilitating tissue adhesion and growth and hence endothelialization.

公开(公告)号：US20240197471A1

公开(公告)日：2024-06-20

申请号：US18595011

申请日：2024-03-04

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： J. Brent Ratz ,  Arshad Quadri ,  Luca Pesce

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0008 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0069

Abstract: A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the proximal anchors can extend a significant distance away from the exterior of the frame, such as a length equal to or greater than about one half the diameter of the frame. As another example, the anchors can have looped ends.

公开(公告)号：US20240197470A1

公开(公告)日：2024-06-20

申请号：US18593136

申请日：2024-03-01

Applicant: MEDTRONIC, INC.

Inventor： Timothy KELLEY ,  Victoria TIEN ,  Alaena MAIORANO ,  Geoffrey ORTH ,  Mostafa TOLOUI ,  Michael SCHENDEL ,  Anne BREITHAUPT ,  Vickie PHAM ,  Cathleen BERGIN

IPC: A61F2/24 ,  A61F2/07

CPC classification number: A61F2/2418 ,  A61F2/07 ,  A61F2002/075 ,  A61F2/2475 ,  A61F2/2476 ,  A61F2210/0014 ,  A61F2220/0075 ,  A61F2230/0078 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2250/0098

Abstract: A prosthesis includes a tubular graft, a prosthetic valve component, an inflow stent, an outflow stent, and a plurality of body stents disposed between the inflow and outflow stents. Each stent is a sinusoidal patterned radially-expandable ring having a first set of crowns and a second set of crowns, with the first set of crowns disposed closer to an inflow end of the tubular graft than the second set of crowns. The prosthesis is configured to be resistant to backfolding and/or buckling during deployment thereof.

公开(公告)号：US12005214B2

公开(公告)日：2024-06-11

申请号：US16866377

申请日：2020-05-04

Applicant: V-Wave Ltd.

Inventor： Yaacov Nitzan ,  Boaz Harari ,  Ascher Shmulewitz ,  Tovy Sivan

IPC: A61M27/00 ,  A61F2/24

CPC classification number: A61M27/002 ,  A61F2/2412 ,  A61F2/2418 ,  A61M27/006 ,  A61F2002/249 ,  A61F2220/0058 ,  A61F2220/0066 ,  A61F2230/0013 ,  A61F2230/0078

Abstract: A device for regulating blood pressure in a heart chamber is provided. The device includes a shunt positionable within a septum of the heart. The shunt is designed for enabling blood flow between a loft heart chamber and a right heart chamber, wherein the flow rate capacity of the device is mostly a function of pressure in the left heart chamber.

公开(公告)号：US12004948B2

公开(公告)日：2024-06-11

申请号：US16890905

申请日：2020-06-02

Applicant: Children's Medical Center Corporation ,  President and Fellows of Harvard College ,  Massachusetts Institute of Technology

Inventor： Sophie-Charlotte Hofferberth ,  Pedro J. del Nido ,  Elazer R. Edelman ,  Peter E. Hammer ,  Christopher Payne

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2250/0004 ,  A61F2250/0065 ,  A61F2250/0082

Abstract: A replacement heart valve device is disclosed. In some embodiments, the device includes a frame coupled to one or more leaflets that are moveable between open and closed configurations. In some embodiments, the frame comprises at least two frame sections that join at a pair of commissural posts. In some embodiments, the device may be geometrically accommodating to adapt to different vasculature shapes and sizes and/or to be able to change size while implanted within a growing patient.

公开(公告)号：US20240180701A1

公开(公告)日：2024-06-06

申请号：US18439973

申请日：2024-02-13

Applicant: St. Jude Medical, Cardiology Division, Inc.

Inventor： Michael Shane Morrissey ,  Bruce Edward Frohman ,  Michael William Metz ,  Janis Paulis Skujins ,  David John Copeland ,  Spencer Patrick Brown

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/95 ,  A61F2/9517

Abstract: A delivery device for a collapsible prosthetic heart valve, the delivery device including an inner shaft, a distal sheath disposed about a portion of the inner shaft and forming a compartment with the inner shaft, the compartment being adapted to receive the prosthetic heart valve, the inner shaft and the distal sheath being movable relative to one another, and a handle including a frame having a longitudinal axis, a proximal end and a distal end, the handle further including a deployment actuator and a hub, each of the deployment actuator and the hub being independently capable of opening and closing the compartment, the hub further including a hub actuator coupled to the inner shaft.

公开(公告)号：US20240180544A1

公开(公告)日：2024-06-06

申请号：US18438473

申请日：2024-02-11

Applicant: Valfix Medical Ltd.

Inventor： Eli Bar ,  Elad Yaacoby ,  Dan Salzman

IPC: A61B17/04 ,  A61F2/00 ,  A61F2/24

CPC classification number: A61B17/0401 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0414 ,  A61B2017/0464 ,  A61B2017/0477 ,  A61F2002/0081 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0091 ,  A61F2250/001 ,  A61F2250/0063

Abstract: A method for locking an intrabody implant over a thread passing through the implant. The method includes advancing a lock body, which includes at least one rotatable element, to the implant over the thread. Subsequently to advancing the lock body to the implant, the rotatable element is rotated such that the lock body grips the thread proximally to the implant.

公开(公告)号：US20240173125A1

公开(公告)日：2024-05-30

申请号：US18428630

申请日：2024-01-31

Applicant: Laplace Interventional Inc.

Inventor： Ramji Iyer ,  Lucas Tradd Schneider ,  Gunnar Paul Askegaard

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2/2412 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0006 ,  A61F2250/001 ,  A61F2250/0069

Abstract: Some embodiments described herein include a heart valve replacement system that may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, a prosthetic heart valve of the system includes structural features that securely anchor the prosthetic heart valve to the site of the native heart valve. Such structural features can provide robust migration resistance. In particular implementations, the prosthetic heart valves occupy a smaller delivery profile, thereby facilitating a smaller delivery catheter for advancement to the heart.

公开(公告)号：US11992397B2

公开(公告)日：2024-05-28

申请号：US17057511

申请日：2018-05-23

Applicant: Corcym S.r.l.

Inventor： Giovanni Giordano ,  Monica Francesca Achiluzzi

IPC: A61F2/00 ,  A61F2/24 ,  A61F2/95

CPC classification number: A61F2/0095 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/9524

Abstract: The disclosure relates to a holder (1) for a heart valve prosthesis (100) including a radially contractible armature (102) and a prosthetic valve carried by said armature (102). The holder (1) includes an annular member (2) having a longitudinal axis (xl) and comprising a plurality of supporting formations (3), said supporting formations (3) protruding radially inwardly of said annular member (2), and a locking member (4) configured for coupling with said annular member (2). Each supporting formation (3) includes a coupling profile or feature (9) configured for engaging the armature (102) of a heart valve prosthesis (100). The coupling profile or feature (9) being configured to prevent the displacement of the armature (102) along said longitudinal axis and being configured to prevent rotation of the armature (102) around the longitudinal axis (X1), while leaving the armature (102) unconstrained in a radially inward direction. The locking member (4) is configured to removably mate with the annular member (2) to provide a radial constraint to the armature in a radially inward direction at the supporting formations (3).

公开(公告)号：US20240164894A1

公开(公告)日：2024-05-23

申请号：US18504696

申请日：2023-11-08

Applicant: St. Jude Medical, Cardiology Division, Inc.

Inventor： William H. Peckels ,  Randolf Von Oepen ,  Heath Marnach

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0075 ,  A61F2250/0069

Abstract: A prosthetic heart valve for replacing a native atrioventricular valve includes a collapsible and expandable frame having atrial and ventricular portions each including a circumferential row of cells, and a center portion extending between the atrial and ventricular portion. The atrial portion and the ventricular portion may flare radially outwardly from the center portion in an expanded condition of the frame. A plurality of prosthetic leaflets may be mounted to the frame. At least some of the struts forming the cells in the atrial portion include an undulating structure positioned between two axially extending strut portions, the undulating structure including at least one circumferentially extending strut portion and being configured to dampen forces transmitted across the undulating structure between the two axially extending strut portions