Abstract:
Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
Abstract translation:提供了可用于刺激生长激素的内源性产生或释放的新型杂环芳族化合物,所述化合物具有通式I的通式结构,其中R 1,R 1, R 2,R 3,R 4,Xa,Y,Z和n如本文所述。 本文提供的化合物可用于治疗肥胖症,骨质疏松症(改善骨密度)和改善肌肉质量和肌肉力量。
Abstract:
A method of identifying genes involved in the stimulation of primary T cells comprising the steps of: a) contacting experimental cells with a stimulating agent; b) preparing RNA from said experimental cells at one or more stimulation phases; c) measuring the level of gene expression in the cells; d) comparing the levels of gene expression of said experimental cells to the level of gene expression in control cells that have not been exposed to an stimulation agent; e) identifying genes that are up regulated or down regulated in said experimental cells relative to said control cells.
Abstract:
To communicate in a press-to-talk (PTT) session, a message for requesting a right to talk in the PTT session is sent over a wireless link between a mobile station and a base station system. The message for requesting the right to talk in the PTT session is sent in wireless signaling over the wireless link. An acknowledgment of the wireless signaling carrying the message is received, with the acknowledgment sent by the base station system in response to the control signaling. An indication is provided at the mobile station of the right to talk in response to the acknowledgment.
Abstract:
A method of identifying genes involved in the regulated secretion of cells having secretory lysosomes comprising the steps of: a) exposing experimental cells to an activating agent; b) preparing RNA from said experimental cells at one or more activation phases; c) measuring the level of gene expression in the cells; d) comparing the levels of gene expression of said experimental cells to the level of gene expression in control cells that have not been exposed to an activating agent; e) identifying genes that are up regulated or down regulated in said experimental cells relative to said control cells.
Abstract:
The present invention provides for a scheduling scheme to be used with respect to a given mobile station. It is determined whether the given mobile station is or is not in soft-handoff. This is performed through examining a reduced active set. The reduced active set is based upon the active set, and the selection of the reduced active set includes considerations such as received reverse link channel signal strength. If the mobile station is in soft hand-off or with reduced active set size of greater than one, congestion control scheduling of reverse link communications from the given mobile station is utilized, using a data rate set by the congestion control of the reverse link channel. If the mobile station is not in soft-handoff or with reduced active set size of one, explicit scheduling of the reverse link communications from the given mobile station is utilized, using a data rate set by the explicit data rate control of the reverse link channel.
Abstract:
Apparatus and methods for information transfer using a cache server are disclosed. A user requests a file via a file requesting device, over a network, from a host. The host transfers the file to a cache server over a connection at a first scheduled time. The cache server then transfers the file, over a second network, to a file receiving device at a second scheduled time.
Abstract:
A high speed bias voltage generating circuit 10 for use with semiconductor devices. The bias voltage generating circuit 10 includes three circuits or circuit portions 12 , 14 and 16 which cooperatively control the output voltage and current of the circuit 10. The standby circuit 12 is active during a standby mode. The standby circuit 12 provides.a stable standby voltage Voutstandby for the circuit 10, and generates substantially no current in standby mode. The bias circuit 14 is active during a bias mode and provides a stable bias voltage Voutbias for the circuit 10. The boost circuit 16 is active during the transition from standby mode to bias mode, and is effective to quickly lower or “pull down” the output voltage from Voutstandby to Voutbias.
Abstract:
The present invention relates to improved, efficient chemical syntheses of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and 3-amino-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-AMP).
Abstract:
The present invention discloses an AC polarization circuit of a capacitive sensor, comprising: an AC signal generator, a transducer, a detection circuit, a pickup capacitor C2 and a carrier eliminating capacitor C1. The output end of the AC signal generator is connected with a primary side of the transducer; an intermediate node of a secondary side of the transducer is grounded; one end of the secondary side is connected with one end of the pickup capacitor C2, and the other end of the secondary side is connected with one end of the carrier eliminating capacitor C1; and the other end of the pickup capacitor C2 and the other end of the carrier eliminating capacitor C1 are connected with the detection circuit. The present invention reduces the output impedance of a pickup head by pushing a pickup signal to high frequency through AC polarization.