摘要:
The present invention provides a compression device for selectively applying compressive force to a localized area of interest on the surface of a body that is readily positioned and fastened in place. The device includes a resilient compressible element positioned on a relatively rigid member associated with a clamping frame that at least partially surrounds a limb or other body area of interest. An adjustable closure means is provided for adjustably completing the clamp arrangement to completely enclose said bodily region of interest in a manner that enables the compressible element to be applied to the precise site of interest. The adjustable closure element permits accommodating bodily parts such as limbs of various size and facilitates adjustment of the compressive pressure applied. The device may take a variety of embodiment forms.
摘要:
A guidewire for guiding and exchanging body insertable catheters includes a body insertable guide section and an exchange section, both formed of flexible wire. In one embodiment, a pin connector at the distal end of the exchange section includes a truncated conical head, a shank, and a groove between the head and the shank. A socket connector is attached to the proximal end of the guide section. Four indentations are formed in the socket connector, spaced apart angularly 90.degree. from one another. The maximum diameter of the conical head is greater than the distance between opposed nodules. As, the pin connector is insertable into the socket, it temporarily elastically deforms the socket as the head moves past the nodules. The nodules become captured within the groove, to allow rotation of the exchange section relative to the guide section while preventing any substantial axial relative movement of the sections. The exchange section can be disconnected from the guide section by withdrawing the pin connector proximally, again elastically deforming the socket as the head passes the nodules. The connectors permit repeated connections and disconnections, so the guidewire sections are reusable. In another embodiment, the pin connector has a cylindrical head and a narrower recess adjacent the head, and an indentation is formed in the socket connector with a gradually inclined wall that terminates in a steeply inclined edge.
摘要:
A storage container for catheters having a separable portion of the front wall detachable from the container to ease removal of the catheter from the container is disclosed. The top portion is preferably separated from the side walls along external score lines at the intersection of the front and side walls. The separable portion of the front wall is preferably hinged on the bottom edge, which is perforated, easing complete separation of the separable portion from the front wall. Internal score lines on the inside surface of the separable portion of the front wall, parallel and proximate the external score lines are preferably provided to form flaps when the top portion of the front wall is detached from the container. The flaps prevent the top of the catheter package from falling out of the container. The separable portion of the front wall enables the catheter to be easily removed from the storage container without it being damaged.
摘要:
An open weave fixation device is secured to a distal end region of a catheter or other diagnostic or treatment device, for either temporarily or permanently fixing the device within a body cavity. In one approach, the fixation element is constructed of braided, helically wound filaments of resilient stainless steel. A sheath surrounds the catheter and fixation element to elastically deform the element into a reduced radius configuration to facilitate insertion and deployment. With the fixation element positioned as desired, the sheath is withdrawn to permit the fixation element to self-expand against body tissue, thus to secure the fixation element and catheter. In an alternative arrangement, a dilation balloon surrounds a catheter near its distal end, and in turn is surrounded by a plastically deformable fixation element. Following desired positioning, the balloon is dilated to permanently deform the fixation element into contact with body tissue. In either case, the fixation element can be mounted at its distal end, its proximal end or medially, dependeing upon the particular treatment and the expected duration of fixation. Another approach employs a recovery metal in the fixation element.
摘要:
A prosthesis for transluminal implantation consists of a flexible tubular interbraided structure of metal or polymeric monofilaments, and polymeric multifilament yarns. The prosthesis can be elastically deformed to reduce its diameter through axial elongation. The monofilaments and multifilament yarns are arranged in axially spaced apart helices, concentric on a common central axis of the prosthesis. The monofilaments are selectively shaped before their interbraiding with the multifilament yarns, either by an age-hardening or other heat-setting stage, or a cold-working stage that controllably plastically deforms the strands. The shaped structural strands cooperate to impart to the prosthesis its nominal shape and resilience. The textile strands cooperate to provide a sheeting that occupies interstices between adjacent structural strands, to reduce permeability and thereby enhance the utility of the prosthesis as a vascular graft. An alternative embodiment prosthesis includes elastically and plastically deformable structural strands, selectively plastically deformed by cold-working then interbraided to form the prosthesis.
摘要:
A delivery device for delivering an implantable endoprosthesis with an occlusion region for occluding fluid flow to a desired location in a body lumen. The delivery device includes an outer sleeve and an inner tube terminating at a distal tip. The distal tip is made of one of a dissolvable, bioabsorbable, or deformable material. Upon deployment of the endoprosthesis at the desired location, the shape of the distal tip is altered to a different shape and withdrawn through the constricted region of the endoprosthesis.
摘要:
The medical devices of the invention comprise a portion having a porous surface for release of at least one biologically active agent therefrom. The porous surface is made of a material such as a polymer having a plurality of voids. To load the porous surface with a biologically active agent or drug, an electrophoresis method is employed. In this method, a device having a porous surface is placed into a drug solution or suspension, along with an electrode. An electric current is applied to the device and electrode. Under such a current, the drug, which has a positive or negative charge, will be loaded into the pores or voids of the porous surface.
摘要:
A coating and method for a coating an implantable device or prostheses are disclosed. The coating includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein. The coating further includes a topcoat which covers less than the entire surface of the undercoat and wherein the topcoat comprises a polymeric material substantially free of pores and porosigens. The polymeric material of the topcoat can be a biostable, biocompatible material which provides long term non-thrombogenicity to the device portion during and after release of the biologically active material.
摘要:
A coating and method for a coating an implantable device or prostheses are disclosed. The coating includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein. The coating further includes a topcoat which covers less than the entire surface of the undercoat and wherein the topcoat comprises a polymeric material substantially free of pores and porosigens. The polymeric material of the topcoat can be a biostable, biocompatible material which provides long term non-thrombogenicity to the device portion during and after release of the biologically active material.
摘要:
The present invention provides a length of trilayer, extruded, medical tubing comprising an outer layer, a core layer, and an intermediate tie layer. The outer layer comprises a polymer that is directly bondable, while the core layer comprises a lubricious polymer. The core layer thus defines a lumen that exhibits the desired characteristics, i.e., low friction for the advancement of a guidewire or catheter through the lumen without comprising the strength and stiffness that is desirable in tubing that is to be used in medical devices. Additionally, the tubing is easily coextruded and yet, is not subject to delamination, thus providing the added advantage of providing a reduction in the overall cost of manufacture.