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公开(公告)号:US11460265B2
公开(公告)日:2022-10-04
申请号:US16782855
申请日:2020-02-05
发明人: Jesus S. Gomez
摘要: A buttstock assembly configured to work in conjunction with a compact buffer assembly consisting of a buffer tube, spring and bolt carrier with an integral buffer is provided. The buttstock assembly, buffer tube and bolt carrier are configured to work with AR15/M16 type firearms and their derivatives. By incorporating the buffer onto the bolt carrier, which is used in conjunction with a buffer tube of reduced length, the overall length of the host firearm is reduced by approximately 3.2 inches. No permanent modification need be made to the host firearm in order to utilize the compact buffer assembly and buttstock assembly disclosed herein.
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公开(公告)号:US11246886B2
公开(公告)日:2022-02-15
申请号:US16560826
申请日:2019-09-04
申请人: NUTRITION 21, LLC
发明人: James R. Komorowski
摘要: The present application relates to the treatment of autism and autism spectrum disorders using biotin compositions.
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公开(公告)号:US11067352B2
公开(公告)日:2021-07-20
申请号:US16430865
申请日:2019-06-04
发明人: Jesus S. Gomez
摘要: An improved bolt and bolt carrier with integral gas key having an extension nozzle threadedly secured and pinned to the gas key for use with a direct gas operated firearm is provided. The extension nozzle is designed to receive a portion of the host firearms gas operating system. The firing pin retaining pin is oriented so as to expose its widest profile to the firing pins annular flange, increasing its service life. The bolt has a plurality of lugs extending from its forward end and an extractor recess. The extractor recess is constructed to accommodate an enlarged extractor claw while not undercutting the bolt lugs adjacent thereto. The extractor engages approximately 57% more of a seated ammunition cartridges rim as compared to some prior art AR15/M16 type extractors used with automatic firearms chambered in 6.8 SPC. The result is an improved bolt and bolt carrier which provides for increased operational reliability.
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公开(公告)号:US10967026B2
公开(公告)日:2021-04-06
申请号:US16121054
申请日:2018-09-04
摘要: The present application is directed to composition comprising various maca extracts and the use of such compositions for treating certain diseases, disorders, and conditions.
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公开(公告)号:US10959971B2
公开(公告)日:2021-03-30
申请号:US16670915
申请日:2019-10-31
申请人: NUTRITION 21, LLC
发明人: James R. Komorowski
IPC分类号: A61K31/198 , A61P25/00 , A61K31/045
摘要: The present disclosure relates to the use of inositol-stabilized arginine silicate complexes (“ASI”) with the addition of free inositol (“I”) to form a composition ASI+I for improving cognitive functioning in humans, particularly video game players.
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公开(公告)号:US10900028B2
公开(公告)日:2021-01-26
申请号:US16472771
申请日:2017-12-22
发明人: Li Li , Jiake Bai , Jinliang Gao , Xiaolai Ma
摘要: The invention relates to the field of bioengineering. In particular, the invention relates to a heparinase-producing Pseudomonas stutzeri strain and a heparinase derived therefrom. Furthermore, the invention relates to the preparation and use of the heparinase.
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公开(公告)号:US10857090B2
公开(公告)日:2020-12-08
申请号:US14902714
申请日:2014-07-04
申请人: Stellar Biome Inc.
IPC分类号: A61K8/99 , A61Q11/00 , A61K35/747 , A61K8/64
摘要: Compositions for use in oral hygiene contain a Lactobacillus helveticus strain. Compositions further containing a Lactobacillus plantarum strain, especially Lactobacillus plantarum SD5870, are particularly effective. The combination of Lactobacillus helveticus LAFTI L10 and Lactobacillus plantarum SD5870 synergistically improves oral hygiene. The compositions are particularly useful against dental caries.
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公开(公告)号:US10774048B2
公开(公告)日:2020-09-15
申请号:US16242902
申请日:2019-01-08
发明人: Guozhang Xu , Micheal Gaul , Shyh-Ming Yang , Tianbao Lu , Rui Zhang , Fengbin Song
IPC分类号: A61K31/416 , C07D231/56 , C07D401/06 , C07D405/14 , C07D405/04 , C07D409/04 , C07D403/04
摘要: The present invention is directed to indazole derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.
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公开(公告)号:US10730847B2
公开(公告)日:2020-08-04
申请号:US16195553
申请日:2018-11-19
发明人: Zhihua Sui , Nalin L. Subasinghe
IPC分类号: C07D307/80 , C07D493/04 , C07D405/12 , C07D333/56 , C07D307/81 , C07D277/64 , C07D307/84 , C07D263/56 , C07D307/79 , C07D493/02 , C07D401/12 , C07D333/54 , C07D231/56 , C07D307/82
摘要: The present invention is directed to benzo-fused heterocyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.
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公开(公告)号:US10603006B2
公开(公告)日:2020-03-31
申请号:US14876930
申请日:2015-10-07
发明人: John W. Cromwell
摘要: Predicting gastrointestinal impairment may involve obtaining intestinal sounds of a patient to generate audio data, identifying predefined spectral events in the audio data that are predictive of subsequent gastrointestinal impairment, the spectral events being defined by predefined parameters, and predicting the likelihood of subsequent gastrointestinal impairment relative to the identified spectral events.
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