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    CARTILAGE MOSAIC COMPOSITIONS AND METHODS
    51.
    发明申请
    CARTILAGE MOSAIC COMPOSITIONS AND METHODS 审中-公开

    公开(公告)号：US20190388227A1

    公开(公告)日：2019-12-26

    申请号：US16459136

    申请日：2019-07-01

    Applicant: AlloSource

    Inventor： Carolyn Barrett Rorick ,  Yaling Shi

    IPC: A61F2/30 ,  A61L27/36

    Abstract: Compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles and a biocompatible carrier are provided. Methods of manufacturing cartilage compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles are also provided.

    Cartilage mosaic compositions and methods
    52.
    发明授权
    Cartilage mosaic compositions and methods 有权

    公开(公告)号：US10335281B2

    公开(公告)日：2019-07-02

    申请号：US15608679

    申请日：2017-05-30

    Applicant: AlloSource

    Inventor： Carolyn Barrett ,  Yaling Shi

    IPC: A61F2/30 ,  A61K35/22 ,  A61L27/36

    Abstract: Compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles and a biocompatible carrier are provided. Methods of manufacturing cartilage compositions comprising a cartilage sheet comprising a plurality of interconnected cartilage tiles are also provided.

    System and methods of use for preparing and testing pre-sutured tendon constructs
    53.
    发明授权
    System and methods of use for preparing and testing pre-sutured tendon constructs 有权

    公开(公告)号：US10271964B1

    公开(公告)日：2019-04-30

    申请号：US15880959

    申请日：2018-01-26

    Applicant: Allosource

    Inventor： Adrian C. Samaniego ,  Wendy Desiree Franklin ,  Sarah Song Yi Han ,  Jesse Compton ,  Marina Bull

    IPC: G01L5/00 ,  A61F2/46 ,  G01L5/06 ,  G01L1/04 ,  A61F2/08

    Abstract: There is disclosed a customizable system and methods of use for manufacturing and testing a variety of pre-sutured allograft tendon constructs sutured according to a variety of stitching patterns and featuring a variety of tissue lengths and types. One embodiment includes a triple-channel base having first, second, and third longitudinal channels extending between first and second ends of the base, as well as a plurality of tendon-manipulation accessories. Each of the tendon-manipulation accessories includes a locking-base assembly for selectively securing the accessory to the base such that the multiple tendon-manipulation accessories may be secured to the triple-channel base in a variety of custom arrangements suitable for preparing the variety of pre-sutured constructs and/or for pre-tensioning or testing the variety of the pre-sutured constructs. Other embodiments are also disclosed.

    OSSEOUS-SANDING ACCESSORY SYSTEM
    54.
    发明申请
    OSSEOUS-SANDING ACCESSORY SYSTEM 审中-公开

    公开(公告)号：US20180272446A1

    公开(公告)日：2018-09-27

    申请号：US15838879

    申请日：2017-12-12

    Applicant: Allosource

    Inventor： Denis M. Meade ,  Shane Graham

    IPC: B23D45/00 ,  B24B27/06 ,  B24B23/02

    CPC classification number: B23D45/003 ,  A61B17/147 ,  A61B17/149 ,  A61F2002/4645 ,  B23D45/06 ,  B23D55/00 ,  B24B19/00 ,  B24B23/02 ,  B24B27/0666 ,  B24B45/00

    Abstract: There are disclosed systems and methods for safely and effectively removing the articular cartilage and cortical bone layers from an articular surface of a human cadaveric femoral head. One embodiment includes an osseous-sanding accessory system installed upon a conventional band saw having a motor and a cabinet that houses a pulley coupled with a primary drive shaft rotated by the motor. The accessory system may include a threaded drive shaft coupled with the primary drive shaft, a grinding disk having an abrasive surface and affixed about a distal end of the threaded drive shaft, and a removable accessory table mounted to the band saw below the grinding disk. When the motor rotates the primary drive shaft, and thus the threaded drive shaft, the grinding disk rotates relative to the accessory table and abrades osseous tissues introduced to the abrasive surface of the grinding disk. Other embodiments are also disclosed.

    Enclosure for laser cutting of human tissue
    55.
    发明授权
    Enclosure for laser cutting of human tissue 有权

    公开(公告)号：US09999942B2

    公开(公告)日：2018-06-19

    申请号：US14941275

    申请日：2015-11-13

    Applicant: ALLOSOURCE

    Inventor： Meghan Gabriel ,  Raymond Klein

    IPC: G01N1/00 ,  B23K26/12 ,  B23K26/38 ,  G02B5/20 ,  A61B18/20

    CPC classification number: B23K26/127 ,  A61B18/20 ,  B23K26/38 ,  G02B5/208

    Abstract: There is disclosed a system and method for laser cutting of human allograft tissue. One embodiment includes a laser canister having a housing fabricated with a sterilizable material. The housing defines an interior portion, an exterior portion, and a selectively operable opening into the interior portion. The selectively operable opening includes a hermetic seal to maintain a sterile environment from the exterior portion when the selectively operable opening is closed. The canister includes an infrared (IR) transmissive optical window disposed in the housing and configured to allow a laser beam to penetrate therethrough to the interior portion. The canister also includes an insert within the interior portion configured to support human allograft tissue in a sterile environment, the insert being removable from the housing to move the human allograft tissue into another sterile environment after the housing has been exposed to a non-sterile environment. Other embodiments are also disclosed.

    Composite bone constructs and methods
    58.
    发明授权
    Composite bone constructs and methods 有权

    公开(公告)号：US09730796B2

    公开(公告)日：2017-08-15

    申请号：US14713627

    申请日：2015-05-15

    Applicant: AlloSource

    Inventor： Adrian C. Samaniego ,  Matthew J. Southard ,  Kenneth Blood ,  Richard Dempsey

    IPC: A61F2/28 ,  A61L27/44 ,  A61L27/48

    CPC classification number: A61F2/28 ,  A61F2002/2835 ,  A61L27/44 ,  A61L27/48 ,  A61L2430/02

    Abstract: Embodiments of the present technology include a graft for administration at a treatment site of a patient. The graft may include a human cadaveric bone material bonded together with a polymeric binder. The human cadaveric bone material may include demineralized bone particles. The demineralized bone particles may have an average diameter less than 1.1 mm, less than 750 μm, less than 500 μm, or less than 250 μm. The human cadaveric bone material may include non-demineralized bone, cancellous bone, and/or cortical bone in embodiments. In some embodiments, bone from animals other than humans may be used, and the patient may be an animal other than a human.

    Multi-layer tissue systems and methods
    59.
    发明授权
    Multi-layer tissue systems and methods 有权

    公开(公告)号：US09616152B2

    公开(公告)日：2017-04-11

    申请号：US13894637

    申请日：2013-05-15

    Applicant: AlloSource

    Inventor： Adrian C. Samaniego ,  Ross M. Wilkins

    IPC: A61L26/00 ,  A61L27/36

    CPC classification number: A61L26/0095 ,  A61L27/3604 ,  Y10T156/10

    Abstract: Embodiments of the present invention encompass anti-adhesion wound dressings including patches made from amnion tissue obtained from human birth tissue. Exemplary amnion patches can be fabricated by folding a section of amnion over on itself with the epithelial layer on the outside of the folded patch and the fibroblast layer on the inside of the folded patch. Optionally, individual amnion tissue pieces can be sandwiched together to provide a multi-layer patch. Sufficient pressure is applied to the layered amnion to cause adherence between opposing faces of the fibroblast layers. The pressed fibroblast layers provide mechanical strength to hold the amnion patch together with the epithelial layers on the outsides of the amnion patch.

    High-strength allograft tendon construct
    60.
    发明授权
    High-strength allograft tendon construct 有权
    高强度同种异体移植肌腱构造

    公开(公告)号：US09504557B1

    公开(公告)日：2016-11-29

    申请号：US15073582

    申请日：2016-03-17

    Applicant: Allosource

    Inventor： Adrian Samaniego ,  Matt Southard ,  Wendy Desiree Franklin ,  Jessica Hodgkiss ,  Bilal Karaze

    IPC: A61F2/08

    CPC classification number: A61F2/08 ,  A61F2/0811 ,  A61F2002/087

    Abstract: There is disclosed an apparatus and method of manufacture relating to a pre-sutured, high-strength allograft tendon construct. One embodiment of the allograft tendon construct includes first and second tendon lengths that are positioned longitudinally in parallel to one another. A whip stitched pattern secures the first and second tendon lengths at a free end, forming a stitched end portion that abuts an unstitched middle portion. The whip stitched pattern includes a plurality of sutures that originate adjacent to the free end and progress or advance inward toward the unstitched middle portion. A multiple knot bundle is applied immediately prior to a final suture, such that the final suture loops about the multiple knot bundle and locks the multiple knot bundle in place beneath the final suture. Other embodiments are also disclosed.

    Abstract translation: 公开了一种与预缝合的高强度同种异体移植腱构造有关的装置和制造方法。 同种异体移植腱构造的一个实施方案包括彼此平行地纵向定位的第一和第二腱长度。 鞭状缝合图案将第一和第二腱长度固定在自由端，形成邻接未缝合的中间部分的缝合端部。 鞭子缝合图案包括起始于自由端的多个缝合线，并且朝向未缝合的中间部分前进或前进。 在最后缝合之前立即应用多重结束，使得最终缝合线围绕多个结束缠绕，并将多个结束锁定在最终缝合线的下方。 还公开了其他实施例。

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