METHOD AND SYSTEM FOR OPTIMIZING ELECTRODE ARRAY STRUCTURE IN ELECTROTHERAPY

    公开(公告)号:US20240261585A1

    公开(公告)日:2024-08-08

    申请号:US18568748

    申请日:2022-05-16

    CPC classification number: A61N1/40

    Abstract: A method of optimizing an electrode array structure in electrotherapy, the method comprising: obtaining information on a region-of-interest (ROI) and critical organs from input patient data; setting an overall shape and an overall area of an electrode array based on the obtained information on the region-of-interest (ROI) and critical organs; setting an area ratio occupied by a plurality of unit electrodes constituting the electrode array to the overall area of the electrode array; repeatedly performing the setting of the overall shape and the overall area and/or the setting of the area ratio until an electric field transmitted to the region-of-interest (ROI) and the critical organs is optimized; and deriving a customized electrode array structure in which the electric field is optimized; is provided

    MODIFIED NUCLEIC ACID INHIBITING MICRO RNA, AND USE THEREOF

    公开(公告)号:US20240254480A1

    公开(公告)日:2024-08-01

    申请号:US17059692

    申请日:2019-05-31

    CPC classification number: C12N15/113 C12N15/63 C12N2310/141 C12N2310/332

    Abstract: Provided is a modified nucleic acid that inhibits microRNA, and a use thereof. The modified nucleic acid that inhibits microRNA, according to the present invention, can strongly bond with microRNA by consecutively arranging at least two micro RNA target sites comprising a complementarily-bonding nucleotide sequence of a minimum of six on a micro RNA seed region, and, as a result of the insertion of an abasic spacer between the micro RNA target sites, not only effectively inhibits the micro RNA, but also has the benefit of the sequence inserted in the modified nucleic acid preventing inadvertent bonding with another micro RNA, and not only canonical target but also non-canonical target recognition of micro RNA such as a nucleation bulge site and G:A or G:U wobble arrangement sites can be used, and it is possible to selectively inhibit biological functions taking place due to non-canonical target recognition of micro RNA.

    Augmented reality display having improved FOV, and waveguide device and diffractive optical structures thereof

    公开(公告)号:US12044848B2

    公开(公告)日:2024-07-23

    申请号:US17434690

    申请日:2020-02-26

    Inventor: Hwi Kim

    CPC classification number: G02B27/0101 G02B5/3025 G02B6/0023 G02B6/005

    Abstract: Various embodiments may provide an augmented reality display having an improved FOV, and a waveguide device and diffractive optical structures thereof. The augmented reality display may comprise: a light source configured to generate light related to an image; and the waveguide device for outputting at least a part of the light. The waveguide device may comprise: a waveguide for guiding light therein; and the diffractive optical structures arranged on a first surface and a second surface of the waveguide. The diffractive optical structures may comprise: a first polarization structure arranged on the first surface of the waveguide to transmit, to the outside of the waveguide, first polarized light selected from external light and reflect, to the inside of the waveguide, second polarized light selected from light guided inside the waveguide device; and a second polarization structure arranged on the second surface of the waveguide to output at least a part of the second polarized light to the outside of the waveguide.

    PUNCHING-TYPE IRIDOTOMY INSTRUMENT
    55.
    发明公开

    公开(公告)号:US20240238122A1

    公开(公告)日:2024-07-18

    申请号:US18288336

    申请日:2022-04-29

    CPC classification number: A61F9/00763 A61F9/00781

    Abstract: The present invention relates to a punching-type iridotomy instrument, and more particularly, to a punching-type iridotomy instrument which, in iridectomy, increases the size and positioning accuracy iris incision through structural improvement in a perforation method, thereby shortening the surgery time and facilitating the convenience of surgical procedures. According to the present invention, the punching-type iridotomy instrument includes a grip manipulation part configured to be manipulated to be opened or closed by a user while being held by the user's hand, an extension shaft extending from the grip manipulation part, and a punching operating unit extending from the extension shaft and configured to perform an operation of forming a hole in a predetermined site of a peripheral portion of an iris in conjunction with an operation of the grip manipulation part performed by the user's manipulation, in which the grip manipulation part includes a first round shaft extending from a rear side of the extension shaft and having a first finger grip ring formed at an end of the first round shaft and configured to be fitted with the user's thumb, a second round shaft hingedly coupled to a predetermined position on the extension shaft by a pivot pin and having a second finger grip ring formed at an end of the second round shaft and configured to be fitted with the user's ring finger, the second round shaft being configured to implement a rotational operation related to a motion of the ring finger fitted into the second finger grip ring, a spring disposed between the first and second round shafts and configured to exert elasticity for pushing the second round shaft, and a wire configured to connect the second round shaft and the punching operating unit while passing through the extension shaft and operate the punching operating unit in conjunction with a rotational operation of the second round shaft.

    METHOD AND DEVICE FOR BUILDING VULNERABILITY DATABASE

    公开(公告)号:US20240232380A9

    公开(公告)日:2024-07-11

    申请号:US18142257

    申请日:2023-05-02

    CPC classification number: G06F21/577 G06F21/552

    Abstract: According to some exemplary embodiments of the present disclosure, disclosed is a method for building a vulnerability database, which is performed by a computing device. The method may include collecting a security patch from a data source based on a direct patch link; collecting the security patch from the data source based on an indirect patch link; and collecting the security patch from the data source based on an invisible patch link. The patch information of a vulnerability can be used for verifying the existence of the vulnerability, as well as fixing the vulnerability of target software.

    UWB-BASED INDOOR POSITIONING SYSTEM AND METHOD USING OUT-OF-BAND MANAGEMENT

    公开(公告)号:US20240223999A1

    公开(公告)日:2024-07-04

    申请号:US18399813

    申请日:2023-12-29

    CPC classification number: H04W4/029 H04W4/33

    Abstract: An UWB-based indoor positioning system using out-of-band management includes a plurality of nodes that individually broadcast an UWB broadcast message through an ultra-wide band (UWB) channel; and a remote positioning server for receiving a response message to the UWB broadcast message through an out-of-band network, calculating a time of flight (ToF) between the nodes based on the identification information and timestamp information of each of the nodes included in the response message and producing a positioning information of each of the nodes by calculating a distance between the nodes using the calculated ToF. The UWB-based indoor positioning system and method using out-of-band management can significantly improve node scalability and flexibility in the UWB positioning system through the unification of processes between anchor/tag nodes and simplification of the initial registration procedure.

Patent Agency Ranking