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51.发明授权公开(公告)号：US09097632B2
公开(公告)日：2015-08-04
申请号：US13778720
申请日：2013-02-27
发明人： Reinhard Lihl , Rainer Wogritsch , Heinz Plank
IPC分类号： F25D25/00 , F25B19/00 , F25D23/00 , F24F3/16 , G01N1/42 , B29C45/00 , G01Q30/10 , G02B7/00 , G21K7/00 , B29K83/00
CPC分类号： G01N1/42 , B29C45/0053 , B29C2045/0075 , B29K2083/005 , G01Q30/10 , G02B7/007 , G21K7/00
摘要： In a device (1) for rapid pressure-freezing an aqueous sample (3), such as a biological specimen, a pressurized cooling medium can be fed into a high-pressure chamber (11) into which a sample holder (30) containing a sample (3) is inserted and which is sealed with a pressure-tight seal, to the location of the sample holder (30) held therein. The high-pressure chamber (11) comprises a viewing window structure (2) with a pressure-tight window (20), through which light can be directed from the outside onto the sample (3) located in the sample holder (30). The window (20) can comprise a transparent window element made of a high-pressure-resistant material, wherein the window element (20) is held by a pressure- and temperature-resistant window bearing provided in the high-pressure chamber.
摘要翻译： 在用于快速冷冻含水样品（3）（例如生物样品）的装置（1）中，加压冷却介质可以被供给到高压室（11）中，其中含有 将样品（3）插入并且用耐压密封件密封到保持在其中的样品保持器（30）的位置。 高压室（11）包括具有耐压窗（20）的观察窗结构（2），光可从外部引导到位于样品架（30）中的样品（3）上。 窗口（20）可以包括由耐高压材料制成的透明窗口元件，其中窗口元件（20）由设置在高压室中的耐压耐温窗口轴承保持。
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53.发明申请公开(公告)号：US20130133342A1
公开(公告)日：2013-05-30
申请号：US13666776
申请日：2012-11-01
发明人： Reinhard LIHL , Robert RANNER
摘要： For cooled processing of a sample, a system for cooling the sample includes a holding device (22) for receiving the sample in a sample holder (20), as well as a cooling chamber (12) that surrounds the position (P) of the sample mounted on the holding device. Provided in the cooling chamber (12) is a window through which a tool receptacle (16) for receiving a tool (W) for processing the sample projects into the cooling chamber (12). The holding device (22) is coolable to a settable temperature by means of a fluid coolant, and ensures cooling of the sample. For this, a coolant, e.g. liquid nitrogen, flows through a coolant conduit of the holding device (22), which conduit is furnished with the coolant at the input end (31) and opens at the output end (41) into the cooling chamber (12), which in this fashion is filled with coolant gas.
摘要翻译： 对于样品的冷却处理，用于冷却样品的系统包括用于将样品接收在样品保持器（20）中的保持装置（22）以及围绕所述样品保持器的位置（P）的冷却室（12） 样品安装在保持装置上。 在冷却室（12）中设置有用于接收用于处理样品的工具（W）投入冷却室（12）的工具容器（16）的窗口。 保持装置（22）通过流体冷却剂可冷却至可设定的温度，并且确保样品的冷却。 为此，例如冷却剂。 液氮流过保持装置（22）的冷却剂导管，该导管在输入端（31）处配备有冷却剂，并在输出端（41）处打开进入冷却室（12），在该冷却室 时尚充满冷却剂气体。
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公开(公告)号：US20040244548A1
公开(公告)日：2004-12-09
申请号：US10709871
申请日：2004-06-02
IPC分类号： B26D001/00 , B26D003/00 , G02B021/06
CPC分类号： G01N15/06 , G02B21/0004 , G02B21/24 , Y10T83/04
摘要： In cutting devices (10), in particular microtomes or ultramicrotomes (24), it is necessary to preset the specimen onto the knife (14). To improve the accuracy and reproducibility of this presetting operation, which is intended to ensure the quickest and most accurate possible positioning of the knife (14) relative to the specimen, a pivotable observation device (10), in particular a stereomicroscope, is provided. The observation device (10) is coupled to a pivoting device (28) that comprises a positioning device (29). The positioning device (29) is embodied in such a way that a positioning of the observation device (10) at a defined angle is possible.
摘要翻译： 在切割装置（10），特别是切片机或超薄切片机（24）中，需要将样本预设到刀（14）上。 为了提高这种预设操作的精度和再现性，其旨在确保刀（14）相对于试样的最快和最准确的可能的定位，提供了一种可枢转的观察装置（10），特别是立体显微镜。 观察装置（10）联接到包括定位装置（29）的枢转装置（28）。 定位装置（29）以使得观察装置（10）以确定的角度定位成为可能的方式实现。
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公开(公告)号：US20020193814A1
公开(公告)日：2002-12-19
申请号：US10153949
申请日：2002-05-23
发明人： Michael Zimmermann , Anton Lang , Heinz Plank , Rainer Wogritsch
IPC分类号： A61B017/08
摘要： A container (2) for tissue preparation for the tissue embedding, having a base body (4), that is formed out cylindrical shaped side wall (5), a floor (6) and several bridges (50). The bridges (50) subdivide the container (2) in several sub-containers (52). The side wall (5) has a plurality of slit shaped openings (12), that extend essentially over the total height of the side wall (5).
摘要翻译： 一种用于组织包埋的组织制剂的容器（2），具有形成为圆柱形侧壁（5），底板（6）和多个桥（50）的基体（4）。 桥梁（50）将容器（2）细分成几个子容器（52）。 侧壁（5）具有多个狭缝形状的开口（12），其基本上在侧壁（5）的总高度上延伸。
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公开(公告)号：US20020150510A1
公开(公告)日：2002-10-17
申请号：US10100850
申请日：2002-03-18
发明人： Reinhard Lihl , Guenther Bock , Ian Lamswood , Michael Zimmermann
IPC分类号： B01L003/00
CPC分类号： G01N1/36 , G01N1/31 , Y10T436/11 , Y10T436/112499 , Y10T436/115831
摘要： An apparatus (1) for tissue preparation for the tissue embedding, having a transport plate (15) that is surrounded by a housing (5). The housing defines an inner upper side (8a), a heating and cooling device (3), that is provided on the inner upper side (8a) of the housing (5) and a mechanic module (24) for turning the transport plate (15) and for raising and lowering the transport plate (15). The mechanic module (24) comprises a first motor (42) exclusively for turning the transport plate (15) around an axle (18) and a second motor (44) exclusively for raising and lowering the transport plate (15) in the direction of the axle (18).
摘要翻译： 一种用于组织包埋的组织制备的装置（1），具有由壳体（5）包围的传送板（15）。 壳体限定设置在壳体（5）的内侧上侧（8a）上的内部上侧（8a），加热和冷却装置（3）以及用于转动运送板的机械模块（24） 15）并且用于升高和降低运输板（15）。 机械模块（24）包括专门用于使运输板（15）围绕轴（18）转动的第一马达（42）和专门用于沿运输板（15）的方向升高和降低运输板（15）的第二马达（44） 轴（18）。
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