公开(公告)号：US07700736B2

公开(公告)日：2010-04-20

申请号：US10123322

申请日：2002-04-15

申请人： Kevin P. Baker ,  Maureen Beresini ,  Laura DeForge ,  Luc Desnoyers ,  Ellen Filvaroff ,  Wei-Qiang Gao ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Steven Sherwood ,  Victoria Smith ,  Timothy A. Stewart ,  Daniel Tumas ,  Colin K. Watanabe ,  William I. Wood ,  Zemin Zhang

发明人： Kevin P. Baker ,  Maureen Beresini ,  Laura DeForge ,  Luc Desnoyers ,  Ellen Filvaroff ,  Wei-Qiang Gao ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Steven Sherwood ,  Victoria Smith ,  Timothy A. Stewart ,  Daniel Tumas ,  Colin K. Watanabe ,  William I. Wood ,  Zemin Zhang

IPC分类号： C07K16/18 ,  C12P21/08

CPC分类号： C07K14/4748 ,  A61K38/00 ,  A61K39/00 ,  A61K39/0011 ,  C07K1/00 ,  C07K14/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K14/705 ,  C07K14/70578 ,  C07K14/82 ,  C07K16/18 ,  C07K17/00 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N5/06 ,  C12N9/00 ,  C12N9/001 ,  C12N9/1051 ,  C12N15/00 ,  C12N2799/026 ,  C12P21/02 ,  C12P21/06 ,  C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5008 ,  G01N33/5011 ,  G01N33/5014 ,  G01N33/502 ,  G01N33/5044 ,  G01N33/505 ,  G01N33/5061 ,  G01N33/53 ,  G01N33/574 ,  G01N33/57484 ,  G01N33/68 ,  G01N33/6845 ,  G01N2800/042 ,  Y10S530/828 ,  Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07601514B2

公开(公告)日：2009-10-13

申请号：US11945176

申请日：2007-11-26

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Daniel Tumas ,  Colin K. Watanabe ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Daniel Tumas ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C12P21/02 ,  C12N15/09 ,  C12N15/64 ,  C07K14/47

CPC分类号： C07K14/47

摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.

摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。

公开(公告)号：US20090226953A1

公开(公告)日：2009-09-10

申请号：US12270133

申请日：2008-11-13

申请人： Kevin P. Baker ,  Luc Desnoyers ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Victoria Smith ,  Jean-Philippe F. Stephan ,  Colin K. Watanabe ,  William I. Wood

发明人： Kevin P. Baker ,  Luc Desnoyers ,  Mary E. Gerritsen ,  Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  Victoria Smith ,  Jean-Philippe F. Stephan ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C12Q1/68 ,  C07K14/00

CPC分类号： C07K14/705 ,  C07K14/47 ,  G01N33/574

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

公开(公告)号：US07582293B2

公开(公告)日：2009-09-01

申请号：US10243425

申请日：2002-09-12

申请人： Audrey Goddard ,  Austin L. Gurney ,  Paul J. Godowski ,  William I. Wood ,  Mary Gerritsen

发明人： Audrey Goddard ,  Austin L. Gurney ,  Paul J. Godowski ,  William I. Wood ,  Mary Gerritsen

IPC分类号： A61K39/395

CPC分类号： C07K14/47 ,  C07K14/705

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods, for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含这些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明多肽的嵌合多肽分子，与本发明多肽结合的抗体以及用于产生本发明多肽的方法 本发明。

公开(公告)号：US07495083B2

公开(公告)日：2009-02-24

申请号：US10176918

申请日：2002-06-20

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

IPC分类号： C07K16/00 ,  A61K39/395 ,  A61K39/00 ,  C12P21/08 ,  C07K14/00 ,  C07K5/00

CPC分类号： C07K14/47 ,  A01K2217/075 ,  A01K2227/105 ,  A61K38/00 ,  A61K39/00 ,  C07K14/4748 ,  C07K14/705 ,  C07K14/82 ,  C07K16/00 ,  C07K16/18 ,  C07K16/28 ,  C07K2319/30 ,  C12N9/90 ,  C12N2799/026 ,  C12Q1/6816 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5082 ,  G01N33/5308 ,  G01N33/574 ,  G01N33/57411 ,  G01N33/57415 ,  G01N33/57419 ,  G01N33/57423 ,  G01N33/57434 ,  G01N33/57484 ,  G01N33/57488 ,  G01N33/57492 ,  G01N2500/10 ,  C12Q2563/131 ,  C12Q2527/137

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07495082B2

公开(公告)日：2009-02-24

申请号：US10140927

申请日：2002-05-07

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

IPC分类号： C07K16/00

CPC分类号： C07K14/4748 ,  A61K38/00 ,  A61K39/00 ,  A61K39/0011 ,  C07K1/00 ,  C07K14/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K14/705 ,  C07K14/70578 ,  C07K14/82 ,  C07K16/18 ,  C07K17/00 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N5/06 ,  C12N9/00 ,  C12N9/001 ,  C12N9/1051 ,  C12N15/00 ,  C12N2799/026 ,  C12P21/02 ,  C12P21/06 ,  C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5008 ,  G01N33/5011 ,  G01N33/5014 ,  G01N33/502 ,  G01N33/5044 ,  G01N33/505 ,  G01N33/5061 ,  G01N33/53 ,  G01N33/574 ,  G01N33/57484 ,  G01N33/68 ,  G01N33/6845 ,  G01N2800/042 ,  Y10S530/828 ,  Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07488796B2

公开(公告)日：2009-02-10

申请号：US10012753

申请日：2001-12-07

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Colin K. Watanabe ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C07K14/435 ,  C07K14/00

CPC分类号： C07K14/47 ,  C07K14/575 ,  C07K2319/30 ,  C07K2319/40

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US20090010936A1

公开(公告)日：2009-01-08

申请号：US11932861

申请日：2007-10-31

申请人： Diane Pennica ,  Victoria Smith ,  William I. Wood

发明人： Diane Pennica ,  Victoria Smith ,  William I. Wood

IPC分类号： A61K39/395 ,  C07K16/18 ,  C12N15/11 ,  C12N15/00 ,  C12N5/06 ,  C12P21/04 ,  A61P31/00

CPC分类号： C12N15/1034 ,  A61K38/1709 ,  A61K2039/505 ,  C07K14/47 ,  C07K2319/00 ,  C12N15/85 ,  G01N33/574 ,  A61K2300/00

摘要： The present invention is directed to novel polypeptides having sequence similarity to Stra6, a murine retinoic acid responsive protein, and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及与Stra6，鼠视黄酸反应性蛋白质以及编码这些多肽的核酸分子具有序列相似性的新型多肽。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07449551B2

公开(公告)日：2008-11-11

申请号：US11355441

申请日：2006-02-15

申请人： Audrey Goddard ,  Austin L. Gurney ,  Paul J. Godowski ,  William I. Wood ,  Napoleone Ferrara

发明人： Audrey Goddard ,  Austin L. Gurney ,  Paul J. Godowski ,  William I. Wood ,  Napoleone Ferrara

IPC分类号： C07K14/00 ,  C07K7/00 ,  A61K39/00

CPC分类号： C07K14/47 ,  C07K16/18 ,  C07K16/28

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07425609B2

公开(公告)日：2008-09-16

申请号：US10141706

申请日：2002-05-08

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

IPC分类号： C07K14/00 ,  C12Q1/68 ,  A61K39/00

CPC分类号： C07K14/4748 ,  A61K38/00 ,  A61K39/00 ,  A61K39/0011 ,  C07K1/00 ,  C07K14/00 ,  C07K14/47 ,  C07K14/4703 ,  C07K14/705 ,  C07K14/70578 ,  C07K14/82 ,  C07K16/18 ,  C07K17/00 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  C12N5/06 ,  C12N9/00 ,  C12N9/001 ,  C12N9/1051 ,  C12N15/00 ,  C12N2799/026 ,  C12P21/02 ,  C12P21/06 ,  C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5008 ,  G01N33/5011 ,  G01N33/5014 ,  G01N33/502 ,  G01N33/5044 ,  G01N33/505 ,  G01N33/5061 ,  G01N33/53 ,  G01N33/574 ,  G01N33/57484 ,  G01N33/68 ,  G01N33/6845 ,  G01N2800/042 ,  Y10S530/828 ,  Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。