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公开(公告)号：US20140187989A1
公开(公告)日：2014-07-03
申请号：US14133242
申请日：2013-12-18
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh H. Thakur , Barun Maskara , Shantha Arcot-Krishnamurthy , Shibaji Shome , Sunipa Saha , Allan C. Shuros
IPC: A61B5/0452
CPC classification number: A61B5/0452 , A61B5/04012 , A61B5/0422 , A61B5/6858 , A61B18/1492 , A61B2018/00357 , A61B2018/00577
Abstract: A method for mapping an anatomical structure includes sensing activation signals of physiological activity with a plurality of electrodes disposed in or near the anatomical structure, each activation signal having an associated cycle length, estimating an action potential duration and diastolic interval for each cycle length, generating a restitution curve based on the estimated action potential duration and diastolic interval from a preceding cycle length, iteratively optimizing each estimated action potential duration and corresponding diastolic interval to maximize a functional relationship between the estimated action potential duration and estimated diastolic interval from preceding cycle length, and generating an action potential duration restitution curve based on the optimized action potential durations and diastolic intervals.
Abstract translation: 用于映射解剖结构的方法包括用设置在解剖结构中或附近的多个电极感测生理活动的激活信号，每个激活信号具有相关联的周期长度，估计每个周期长度的动作电位持续时间和舒张期间隔，产生 基于来自前一周期长度的估计动作电位持续时间和舒张期间隔的恢复曲线，迭代地优化每个估计动作电位持续时间和相应的舒张期间隔，以使估计的动作电位持续时间与前一周期长度的估计的舒张期之间的功能关系最大化， 并基于优化的动作电位持续时间和舒张期间隔产生动作电位持续时间恢复曲线。
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公开(公告)号：US20140180151A1
公开(公告)日：2014-06-26
申请号：US14134414
申请日：2013-12-19
Applicant: Boston Scientific Scimed, Inc.
Inventor： Barun Maskara , Shantha Arcot-Krishnamurthy , Pramodsingh H. Thakur , Allan C. Shuros , Sunipa Saha , Shibaji Shome
CPC classification number: A61B5/044 , A61B5/0422 , A61B5/6858 , A61B5/7203 , A61B18/1492 , A61B2017/00044 , A61B2017/00048 , A61B2017/00053 , A61B2018/00666 , A61B2018/00839
Abstract: A method for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of electrodes disposed in or near the anatomical structure, identifying at least one of the electrodes not in direct contact with the anatomical structure, and adjusting the activation signals sensed by each of the plurality of electrodes based on the activation signals sensed by the identified at least one of the electrodes not in direct contact with the anatomical structure.
Abstract translation: 用于映射解剖结构的方法包括用设置在解剖结构中或附近的多个电极来感测内在生理活动的激活信号，识别不与解剖结构直接接触的电极中的至少一个，以及调节感测到的激活信号 基于由所识别的不与解剖结构直接接触的至少一个电极感测的激活信号，由多个电极中的每一个电极。
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53.发明申请REAL-TIME SIGNAL COMPARISON TO GUIDE ABLATION CATHETER TO THE TARGET LOCATION 审中-公开实时信号与目标位置引导导管的对比公开(公告)号：US20140107453A1
公开(公告)日：2014-04-17
申请号：US14053573
申请日：2013-10-14
Applicant: Boston Scientific Scimed Inc.
Inventor： Barun Maskara , Pramodsingh H. Thakur , Shantha Arcot-Krishnamurthy , Shibaji Shome , Sunipa Saha , Allan C. Shuros
CPC classification number: A61B5/068 , A61B5/0422 , A61B5/066 , A61B5/4836 , A61B5/6858 , A61B5/742 , A61B5/746 , A61B18/1492 , A61B2017/00044 , A61B2017/00053 , A61B2017/00243 , A61B2017/003 , A61B2018/00267 , A61B2018/00351 , A61B2018/00839 , A61B2018/00898 , A61B2018/00904
Abstract: A catheter system includes a plurality of mapping electrodes, an electrode movable relative to the plurality of mapping electrodes, and a guidance system coupled to the plurality of mapping electrodes and the ablation electrode. The guidance system is configured to receive signals associated with intrinsic cardiac activity sensed by the plurality of mapping electrodes and the movable electrode, and to correlate in real-time the intrinsic cardiac activity sensed by the movable electrode with the intrinsic cardiac activity sensed by the plurality of mapping electrodes based on the signals received by the plurality of mapping electrodes and movable electrode to determine a location of the movable electrode with respect to the plurality of mapping electrodes.
Abstract translation: 导管系统包括多个映射电极，相对于多个映射电极可移动的电极，以及耦合到多个映射电极和消融电极的引导系统。 引导系统被配置为接收与由多个映射电极和可移动电极感测的固有心脏活动相关联的信号，并且实时地将由可移动电极感测的固有心脏活动与由多个映射电极和可移动电极感测的固有心脏活动相关联 基于由多个映射电极和可移动电极接收的信号的映射电极，以确定可移动电极相对于多个映射电极的位置。
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54.发明申请AUGMENTED SIGNAL VECTOR ANALYSIS TO SUPPRESS GLOBAL ACTIVATION DURING ELECTROPHYSIOLOGY MAPPING 有权增强信号矢量分析在电生理映射期间抑制全球激活公开(公告)号：US20130345577A1
公开(公告)日：2013-12-26
申请号：US13923012
申请日：2013-06-20
Applicant: Boston Scientific Scimed, Inc.
Inventor： Pramodsingh Hirasingh Thakur , Barun Maskara , Allan C. Shuros , Sunipa Saha , Shibaji Shome
IPC: A61B5/042
CPC classification number: A61B5/0422 , A61B5/046 , A61B5/6859 , A61B18/1492
Abstract: Electrical activity propagation along an electrode array within a cardiac chamber is reconstructed. Signals are sampled from the electrode array including signals from a channel of interest. An N-dimensional signal vector is then constructed using signals from N neighboring channels referenced to the channel of interest. A change in the N-dimensional signal vector over time is then determined and compared to a predetermined threshold to establish whether local activation has occurred on the channel of interest.
Abstract translation: 重建沿心室内电极阵列的电活动传播。 从包括来自感兴趣信道的信号的电极阵列采样信号。 然后使用来自参考感兴趣信道的N个相邻信道的信号来构造N维信号向量。 然后确定N维信号矢量随时间的变化，并将其与预定阈值进行比较，以确定在感兴趣信道上是否发生了局部激活。
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公开(公告)号：US10827939B2
公开(公告)日：2020-11-10
申请号：US15227758
申请日：2016-08-03
Applicant: Boston Scientific Scimed, Inc.
Inventor： Sandra Nagale , Bryan Clark , Allan Shuros , Ding He , Dennis Werner , Lynne Swanson , Charles Gibson , Amedeo Chiavetta , Michael Peterson , Shibaji Shome , Mark Boden , Timothy Harrah
Abstract: The present disclosure relates to the field of tissue mapping and ablation. Specifically, the present disclosure relates to expandable medical devices for identifying and treating local anatomical abnormalities within a body lumen. More specifically, the present disclosure relates to systems and methods of focal treatment for overactive bladders.
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Patent Agency Ranking
56.发明授权公开(公告)号：US10595739B2
公开(公告)日：2020-03-24
申请号：US15651211
申请日：2017-07-17
Applicant: Boston Scientific Scimed Inc.
Inventor： Pramodsingh Hirasingh Thakur , Shibaji Shome , Allan C. Shuros , Shantha Arcot-Krishnamurthy , Barun Maskara , Sunipa Saha
Abstract: An anatomical mapping system including a plurality of mapping electrodes disposed in or near an anatomical structure and configured to detect activation signals of physiological activity, each of the plurality of mapping electrodes having an electrode location, and a processing system associated with the plurality of mapping electrodes, and configured to record the detected activation signals and associate one of the plurality of mapping electrodes with each recorded activation signal. The processing system further configured to determine a dominant frequency at each electrode location, and determine a wavefront vector at each electrode location based on a difference between the dominant frequency at a first electrode location and the dominant frequency at neighboring electrode locations.
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公开(公告)号：US10575900B2
公开(公告)日：2020-03-03
申请号：US15355745
申请日：2016-11-18
Applicant: Boston Scientific Scimed Inc.
Inventor： Jacob I. Laughner , Jason J. Hamann , Shibaji Shome , Allan C. Shuros , Mary M. Byron , Paul Hultz , Pramodsingh H. Thakur
Abstract: A catheter system includes a catheter comprising a tip assembly, the tip assembly having a plurality of electrodes and the plurality of electrodes are configured to measure electrical signals. The system also includes a processing unit configured to: receive a first electrical signal sensed by a first electrode of the plurality of electrodes and a second electrical signal sensed by a second electrode of the plurality of electrodes. A first vector is determined based on the first electrical signal that corresponds to the first electrode. A second vector is determined based on the second electrical signal that corresponds to the second electrode. A resultant vector is determined by summing at least the first vector and the second vector, wherein the resultant vector is indicative of the orientation of the tip assembly.
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58.发明申请公开(公告)号：US20180153426A1
公开(公告)日：2018-06-07
申请号：US15890110
申请日：2018-02-06
Applicant: Boston Scientific Scimed Inc.
Inventor： Pramodsingh H. Thakur , Shibaji Shome , Shantha Arcot-Krishnamurthy , Allan C. Shuros , Barun Maskara , Sunipa Saha
IPC: A61B5/04 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/00 , G06K9/00 , A61B18/14 , A61B18/00
Abstract: A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure, each of the plurality of mapping electrodes having an electrode location. A vector field map which represents a direction of propagation of the activation signals at each electrode location is generated to identify a signature pattern and a location in the vector field map according to at least one vector field template. A target location of the identified signature pattern is identified according to a corresponding electrode location.
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59.发明授权公开(公告)号：US09918649B2
公开(公告)日：2018-03-20
申请号：US14120369
申请日：2014-05-14
Applicant: Boston Scientific Scimed Inc.
Inventor： Pramodsingh H. Thakur , Shibaji Shome , Shantha Arcot-Krishnamurthy , Allan C. Shuros , Barun Maskara , Sunipa Saha
IPC: A61B5/04 , A61N1/00 , A61B5/042 , A61B5/044 , A61B5/0402 , A61B5/00 , A61B5/0452 , G06K9/00 , A61B18/14 , A61B18/00
CPC classification number: A61B5/04011 , A61B5/04012 , A61B5/04023 , A61B5/0422 , A61B5/044 , A61B5/04525 , A61B5/6852 , A61B5/6858 , A61B5/6859 , A61B5/7203 , A61B5/7221 , A61B5/7246 , A61B18/1492 , A61B2018/00357 , A61B2018/00577 , G06K9/00496
Abstract: A method and system for mapping an anatomical structure includes sensing activation signals of intrinsic physiological activity with a plurality of mapping electrodes disposed in or near the anatomical structure, each of the plurality of mapping electrodes having an electrode location. A vector field map which represents a direction of propagation of the activation signals at each electrode location is generated to identify a signature pattern and a location in the vector field map according to at least one vector field template. A target location of the identified signature pattern is identified according to a corresponding electrode location.
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公开(公告)号：US09730603B2
公开(公告)日：2017-08-15
申请号：US14744888
申请日：2015-06-19
Applicant: Boston Scientific Scimed Inc.
Inventor： Jacob I. Laughner , Shibaji Shome , Paul Hultz , Kevin J. Stalsberg , Pramodsingh H. Thakur
IPC: A61B5/044 , A61B5/042 , A61B5/04 , A61B5/0452 , A61B5/00 , A61B5/046 , A61B5/0464 , A61B18/14 , A61B18/00
CPC classification number: A61B5/044 , A61B5/04012 , A61B5/0422 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/6858 , A61B5/7264 , A61B5/743 , A61B18/1492 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839 , A61B2505/05
Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a system for mapping the electrical activity of the heart. The system may include a catheter shaft with a plurality of electrodes. The system may also include a processor. The processor may be capable of collecting a set of signals from at least one of the plurality of electrodes. The set of signals may be collected over a time period. The processor may also be capable of calculating at least one propagation vector from the set of signals, generating a data set from the at least one propagation vector, generating a statistical distribution of the data set and generating a visual representation of the statistical distribution.
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