公开(公告)号：US07769470B1

公开(公告)日：2010-08-03

申请号：US11641860

申请日：2006-12-20

申请人： Ali Rezai ,  John Hall ,  Barry D. Kuban ,  Ken Baker

发明人： Ali Rezai ,  John Hall ,  Barry D. Kuban ,  Ken Baker

IPC分类号： A61N1/04

CPC分类号： A61N1/0529 ,  A61N1/0534

摘要： A device for modulating a volume of neural tissue comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, an actuator mechanism at least partially disposed in the lumen of the cannula; a plurality of leads having at least one electrode disposed thereon, the plurality of leads being coupled to the actuator mechanism to reciprocate between a retracted position wherein the plurality of leads are radially constrained within the lumen and an extended position; and a guide provided at the distal end of the cannula to deflect the plurality of leads radially outwardly into the neural tissue when the actuator mechanism is moved to the extended position.

摘要翻译： 一种用于调节神经组织的体积的装置，包括：套管，其具有近端，远端和至少延伸到所述远端的内腔，致动器机构至少部分地设置在所述套管的内腔中; 多个引线，其上设置有至少一个电极，所述多个引线联接到所述致动器机构以在缩回位置之间往复运动，在所述缩回位置，所述多个引线径向地限制在所述内腔内和延伸位置; 以及引导件，其设置在套管的远端处，以在致动器机构移动到伸出位置时将多个引线径向向外偏转进入神经组织。

公开(公告)号：US07258225B2

公开(公告)日：2007-08-21

申请号：US11092409

申请日：2005-03-28

申请人： John Hall

发明人： John Hall

IPC分类号： B65G11/00 ,  B65G47/34

CPC分类号： B65G47/44 ,  B65G11/206 ,  B65G45/16 ,  B65G69/0441 ,  B65G2201/045

摘要： An apparatus for diverting material in a controlled manner comprising a diverter plate attached to a mounting assembly. The diverter plate is shaped for receiving falling material and facilitating the flow of the material onto a conveyance means or into storage. The mounting assembly comprises a carrier spring assembly that permits the diverter plate to pivot about a shaft and thereby move from a default position to an unload position. The mounting assembly further comprises two adjustable locking mounts that hold the shaft in place and also allow the shaft to be adjustably rotated and thereafter fixed in place. A method for diverting material in a controlled manner comprises the steps of installing the apparatus at a transfer point and activating a first conveyance means that feeds material to the chute. A second conveyance means that receives the material after diversion by the apparatus can optionally be activated.

摘要翻译： 一种用于以受控方式转移材料的装置，包括附接到安装组件的分流板。 分流板被成形为用于接收落下的材料并且便于将材料流到输送装置上或进入储存器中。 安装组件包括载体弹簧组件，其允许分流板围绕轴枢转，从而从默认位置移动到卸载位置。 安装组件还包括两个可调节的锁定安装件，其将轴保持就位并且还允许轴可调节地旋转，然后固定就位。 用于以受控方式转移材料的方法包括以下步骤：将装置安装在转移点处，并启动将材料供给到滑槽的第一输送装置。 第二输送装置可以选择性地启动在装置转移之后接收材料的第二输送装置。

公开(公告)号：US20070091975A1

公开(公告)日：2007-04-26

申请号：US11510269

申请日：2006-08-25

申请人： Mark Notcutt ,  John Hall ,  Long-Sheng Ma

发明人： Mark Notcutt ,  John Hall ,  Long-Sheng Ma

IPC分类号： H01S3/00

CPC分类号： H01S3/02 ,  H01S3/1392 ,  Y10T29/49865 ,  Y10T29/51

摘要： A technique for reducing the vibration sensitivity of laser-stabilizing optical reference cavities is based upon an improved design and mounting method for the cavity, wherein the cavity is mounted vertically. It is suspended at one plane, around the spacer cylinder, equidistant from the mirror ends of the cavity. The suspension element is a collar of an extremely low thermal expansion coefficient material, which surrounds the spacer cylinder and contacts it uniformly. Once the collar has been properly located, it is cemented in place so that the spacer cylinder is uniformly supported and does not have to be squeezed at all. The collar also includes a number of cavities partially bored into its lower flat surface, around the axial bore. These cavities are support points, into which mounting base pins will be inserted. Hence the collar is supported at a minimum of three points.

摘要翻译： 用于降低激光稳定的光学参考腔的振动灵敏度的技术基于用于空腔的改进的设计和安装方法，其中空腔垂直安装。 它悬挂在隔离筒周围的一个平面上，与空腔的镜端等距。 悬挂元件是非常低的热膨胀系数材料的套环，其围绕间隔圆筒并均匀地接触。 一旦套环正确定位，就将其固定就位，以使间隔圆筒均匀地支撑，完全不需要挤压。 轴环还包括围绕轴向孔部分地钻入其下平坦表面的多个空腔。 这些腔是支撑点，安装底座销将插入该支撑点。 因此，衣领至少支持三点。

公开(公告)号：US20060088932A1

公开(公告)日：2006-04-27

申请号：US10733816

申请日：2003-12-10

申请人： Stephen Harrison ,  John Hall ,  Maria Calderon-Cacia ,  Ziyang Zhong ,  Eric Fang ,  Doris Coit ,  Steve Nguyen ,  Angelica Medina-Selby

发明人： Stephen Harrison ,  John Hall ,  Maria Calderon-Cacia ,  Ziyang Zhong ,  Eric Fang ,  Doris Coit ,  Steve Nguyen ,  Angelica Medina-Selby

IPC分类号： C12P21/06 ,  C07H21/04 ,  C12N9/12

CPC分类号： C12N9/1205 ,  C12Q1/485 ,  C12Y207/01037 ,  G01N2500/00

摘要： The invention provides truncated GSK3 polypeptides capable of crystallization, including GSK3α and GSK3β polypeptides, and use of these polypeptides to identify and optimize GSK3 inhibitors. Also provided are GSK3 polypeptides having at least one substituted amino acid that differs from wild-type GSK3, wherein the substituted amino acid is incapable of being phosphorylated. The invention finds use in providing methods of identifying and optimizing compounds useful for treating diseases mediated by GSK3 activity, including Alzheimer's disease, type 2 diabetes, and inflammation.

公开(公告)号：US20060064196A1

公开(公告)日：2006-03-23

申请号：US10883569

申请日：2004-06-30

申请人： Stuart Inkpen ,  Chris Nolan ,  Darryl Pike ,  Heather Rowe ,  John Hall ,  Dana Linfield ,  Joshua Swamidas ,  Chris Dawson ,  Gerard Galway ,  Shawn Walsh ,  Ruth Abraham

发明人： Stuart Inkpen ,  Chris Nolan ,  Darryl Pike ,  Heather Rowe ,  John Hall ,  Dana Linfield ,  Joshua Swamidas ,  Chris Dawson ,  Gerard Galway ,  Shawn Walsh ,  Ruth Abraham

IPC分类号： G06F19/00

CPC分类号： G05B23/0235

摘要： A computer-based fibre production monitoring system includes at least one sensor, and a computer server in communication with the sensors. Each sensor is configured to provide data packets each being associated with a respective threadline and providing a measurement of at least one physical characteristic of a fibre as it is drawn past the sensor on the threadline and wound onto a bobbin. The computer server is configured to provide an analysis of the physical characteristics on a per-threadline basis and/or per-bobbin basis from the measurements. The sensor is configured as an electric field sensor, and includes an insulating substrate, non-contacting electrodes disposed on the substrate, and vias extending transversely through the substrate. The electrodes are interlaced with one another. One portion of the vias is coupled to one portion of the electrodes, and another portion of the vias is coupled to another portion of the electrodes.

摘要翻译： 基于计算机的光纤生产监控系统包括至少一个传感器和与传感器通信的计算机服务器。 每个传感器被配置为提供每个与相应的丝线相关联的数据分组，并且当纤维被绘制通过丝线上的传感器并且卷绕到线轴上时，提供纤维的至少一个物理特性的测量。 计算机服务器被配置为从测量结果提供基于每线纱线和/或每线轴的物理特性的分析。 传感器被配置为电场传感器，并且包括绝缘基板，设置在基板上的非接触电极和横向延伸穿过基板的通孔。 电极彼此交织。 通孔的一部分耦合到电极的一部分，并且通孔的另一部分耦合到电极的另一部分。

公开(公告)号：US20060018024A1

公开(公告)日：2006-01-26

申请号：US10896958

申请日：2004-07-23

申请人： Kyle Bryant ,  John Hall

发明人： Kyle Bryant ,  John Hall

IPC分类号： G02B27/10

CPC分类号： G02B27/0101 ,  G02B2027/0116 ,  G02B2027/0123

摘要： A panoramic see-through optical device in accordance with the present invention includes at least two prisms having a reflective face extending diagonally through the prism. Each prism has one convex surface with a tangent plane thereto, and the two prisms are arranged so that the tangent planes are orthogonal to each other. The device further includes a plurality of display panels corresponding to a respective prism. The display panels are placed about parallel to each tangent plane so that the convex surface of the prism faces the panel. An optical train, which minimally includes a filter and a surface diffractive lens, is located between the display panel and the prism, primarily to correct for chromatic aberration, or color spread. Data from each display panel can be reflected by reflective face internal to the prism and seen by the operator. At the same time, the operator can see directly through the partially reflective face of the prism. The result is a field of view with data from the display panel that is superimposed over the field of view.

摘要翻译： 根据本发明的全景透视光学装置包括至少两个棱镜，其具有斜对角地延伸穿过棱镜的反射面。 每个棱镜具有一个具有切向平面的凸面，并且两个棱镜被布置成使切线平面彼此正交。 该装置还包括对应于相应棱镜的多个显示面板。 显示面板平行于每个切平面放置，使得棱镜的凸面面向面板。 最初包括滤光器和表面衍射透镜的光学系列位于显示面板和棱镜之间，主要用于校正色差或颜色扩展。 来自每个显示面板的数据可以由棱镜内部的反射面反射并被操作者看见。 同时，操作者可以直接看到棱镜的部分反射面。 结果是来自显示面板的数据被叠加在视场上的视野。

公开(公告)号：US20050264873A1

公开(公告)日：2005-12-01

申请号：US10853244

申请日：2004-05-26

申请人： John Hall ,  Jay Vizgaitis

发明人： John Hall ,  Jay Vizgaitis

IPC分类号： G02B5/18 ,  G02B13/00 ,  G02B13/14 ,  G02B13/18 ,  G02B13/22 ,  G02B27/00 ,  G02B27/42

CPC分类号： G02B13/14 ,  G02B13/0095 ,  G02B13/18 ,  G02B13/22 ,  G02B27/0025

摘要： An optical imager for use in the 3-5 micron spectral band. The imager comprises a large aperture positively-powered first objective lens made of a first material for collecting collimated light, and a slightly negatively-powered second objective lens made of a second material spaced behind the first objective lens to provide a color-corrected intermediate focal plane for the collected light. The imager further includes a relay group of three lenses disposed behind the second objective lens for re-imaging the intermediate focal plane.

摘要翻译： 用于3-5微米光谱带的光学成像仪。 该成像器包括由用于收集准直光的第一材料制成的大孔径正动力第一物镜和由间隔在第一物镜之后的第二材料制成的略带负能的第二物镜，以提供经颜色校正的中间焦点 飞机为收集的光。 成像器还包括设置在第二物镜后面的三个透镜的继电器组，用于对中间焦平面重新成像。

公开(公告)号：US20050236886A1

公开(公告)日：2005-10-27

申请号：US11086040

申请日：2005-03-22

申请人： John Hall ,  Jeremy Zills ,  Sik-Kan Huang ,  Byron Cornett

发明人： John Hall ,  Jeremy Zills ,  Sik-Kan Huang ,  Byron Cornett

IPC分类号： B60B27/00

CPC分类号： B60B27/00 ,  Y10T29/49533 ,  Y10T29/49989 ,  Y10T29/49996

摘要： The present invention provides a drum or rotor wheel hub having a cast hub having a machined pilot in a flange portion and a machined pilot in a cylindrical portion, and a cast portion which separates the cylindrical pilot from the flange pilot, whereby a machined radii is not incorporated in the pilot construction.

摘要翻译： 本发明提供一种滚筒或转子轮毂，其具有铸造轮毂，其具有凸缘部分中的加工导向件和圆柱形部分中的加工导向件，以及将圆柱形导向件与凸缘导向件分离的铸造部分，其中加工半径为 未纳入试点工程。

公开(公告)号：US20050199836A1

公开(公告)日：2005-09-15

申请号：US10814355

申请日：2004-03-31

申请人： John Hall

发明人： John Hall

IPC分类号： G03B42/02

CPC分类号： G03B42/08

摘要： An apparatus and method for removing stored energy from a storage phosphor screen in which a radiation image was recorded and then read by collecting stimulated emission from the phosphor sheet. The phosphor sheet is transported along a path in a first direction at a first speed into an erase area having at least one erasing light source. A portion of the phosphor sheet disposed within the erase area is exposed to the light source to affect erasure of the radiation image on the exposed portion of the phosphor sheet. Transport of the phosphor sheet is stopped when the trailing edge of the phosphor sheet enters the erase area and the phosphor sheet dwells within the erase area for a predetermined time period. The phosphor sheet is then transported along the path in a second direction at a second speed, and then transported along the path in the second direction at a third speed when the leading edge exits the erase area.

摘要翻译： 一种用于从存储荧光屏中去除存储的能量的设备和方法，其中记录了放射线图像，然后通过从磷光体片中收集受激发射来读取。 荧光体片沿着第一方向的路径以第一速度传送到具有至少一个擦除光源的擦除区域。 设置在擦除区域内的荧光体片的一部分暴露于光源，以影响荧光片的曝光部分上的放射线图像的擦除。 当荧光体片的后缘进入擦除区域并且荧光体片材在擦除区域内停留预定时间段时，磷光体片的传送停止。 然后以第二速度沿着第二方向沿着路径传送磷光体片，然后当前缘离开擦除区域时以第三速度沿第二方向沿着路径传送。

公开(公告)号：US06929112B2

公开(公告)日：2005-08-16

申请号：US10081389

申请日：2002-02-22

申请人： John Hall

发明人： John Hall

IPC分类号： B65G45/16 ,  B65G45/00

CPC分类号： B65G45/16

摘要： A conveyor belt cleaning system being a torsion blade holder assembly having a mounting sub-assembly and a blade support sub-assembly. The mounting sub-assembly has a first hollow member and a second member situated at least partially therein with torsion elements in the plurality of spaces or cavities between the first hollow member and the second member. The blade support sub-assembly, in which a scraper blade is secured, is attached to the second member such that when the scraper blade meets resistance while scraping the surface of a conveyor belt, the torsion elements are compressed and the blade support sub-assembly with the scraper blade rotates away from the conveyor belt. The blade support sub-assembly includes notched receiving members for receiving the scraper blade, a face plate extending between the notched receiving members approximately parallel to the scraper blade such that at least a portion of the scraper blade rests flush against the face plate when the scraper blade is situated in the notched receiving members, a horizontal blade stabilizer approximately perpendicular to and extending beneath the face plate, and a means for vertically adjusting the scraper blade within the notched receiving members. The means for vertically adjusting is one or more adjustable lock bolts extending upward through the horizontal blade stabilizer for adjusting the scraper blade up and down within the notched receiving members. The torsion blade holder assembly optionally includes a shield and a means for spraying a liquid on the conveyor belt.

摘要翻译： 传送带清洁系统，其是具有安装子组件和叶片支撑子组件的扭转刀片保持器组件。 安装子组件具有第一中空构件和至少部分地位于其中的第二构件，其中在第一中空构件和第二构件之间的多个空间或空腔中具有扭转元件。 其中固定有刮刀的叶片支撑子组件附接到第二构件，使得当刮刀在刮擦输送带的表面时遇到阻力的同时，扭转元件被压缩并且叶片支撑子组件 刮刀从传送带旋转。 叶片支撑子组件包括用于接收刮刀的切口接收构件，在凹口接收构件之间延伸的面板，其大致平行于刮刀，使得当刮刀的至少一部分刮板停靠在面板上时， 叶片位于切口接收构件中，大致垂直于并延伸到面板下方的水平叶片稳定器，以及用于在切口接收构件内垂直调节刮刀的装置。 用于垂直调节的装置是一个或多个可调节的锁定螺栓，其向上延伸穿过水平叶片稳定器，用于在切口接收构件内上下调节刮刀。 扭转刀片保持器组件可选地包括屏蔽件和用于在输送带上喷射液体的装置。