公开(公告)号：US20090131829A1

公开(公告)日：2009-05-21

申请号：US12335769

申请日：2008-12-16

申请人： Dominique Freeman ,  Don Alden

发明人： Dominique Freeman ,  Don Alden

IPC分类号： A61B5/15

CPC分类号： A61B5/15146 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150755 ,  A61B5/15087 ,  A61B5/151 ,  A61B5/15113 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15176 ,  A61B5/15178 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/15194 ,  A61B5/157 ,  A61B5/6886 ,  A61M5/3295

摘要： A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoids may drive the lancet using electromagnetic force. Advancement and retraction of a lancet may be controlled by a feedback loop monitoring the position and velocity of the lancet embodiments of the lancet driver can be configured to follow a predetermined tissue lancing profile. Embodiments of the invention include a lancet and method for using a lancet to maintain the patency of the wound tract once the lancet has cut into the skin.

公开(公告)号：US20090112124A1

公开(公告)日：2009-04-30

申请号：US12326962

申请日：2008-12-03

申请人： Dominique Freeman ,  Don Alden

发明人： Dominique Freeman ,  Don Alden

IPC分类号： A61B5/151 ,  G08B23/00 ,  G10L21/00

CPC分类号： A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150519 ,  A61B5/150572 ,  A61B5/150664 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/150916 ,  A61B5/151 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/1513 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/15182 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/157 ,  A61M37/0015

摘要： A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber. The sample changers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 μL of a body fluid disposed in the sample chamber. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.

摘要翻译： 皮肤穿透系统设置有驱动力发生器和一次性外壳构件。 多个穿透构件定位在一次性外壳构件中。 每个穿透构件联接到驱动力发生器。 多个分析物检测构件各自与穿透构件相关联并且被定位在一次性外壳构件中。 每个分析物检测构件定位在样品室中。 样品更换器具有用于将体液输送到样品室中的开口。 每个分析物检测构件被配置为使用设置在样品室中的小于1μl体液的样品来确定体液中的分析物的浓度。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。

公开(公告)号：US20080214956A1

公开(公告)日：2008-09-04

申请号：US11972028

申请日：2008-01-10

申请人： Barry Dean Briggs ,  Dominique Freeman ,  Don Alden ,  Dirk Boecker

发明人： Barry Dean Briggs ,  Dominique Freeman ,  Don Alden ,  Dirk Boecker

IPC分类号： A61B5/157 ,  A61B5/155

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/15019 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150824 ,  A61B5/150832 ,  A61B5/15087 ,  A61B5/150916 ,  A61B5/150954 ,  A61B5/151 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15174 ,  A61B5/15176 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/1519 ,  A61B5/15194 ,  A61B17/32093 ,  B01L3/5027 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet and a processor coupled to the drive force generator capable of changing the direction and magnitude of force exerted on the lancet during the lancing cycle. The driver further includes a human interface on the housing providing at least one output for communicating with the patient.

摘要翻译： 提供了一种刺血针驱动器，其中驾驶员在穿刺周期期间在柳叶刀上施加驱动力并且在组织部位上使用。 驱动器包括用于使柳叶刀前进的驱动力发生器和与驱动力发生器耦合的处理器，其能够改变在穿刺周期期间施加在刺血针上的力的方向和大小。 驱动器还包括在壳体上的人机接口，提供至少一个用于与患者通信的输出。

公开(公告)号：US20080021491A1

公开(公告)日：2008-01-24

申请号：US11774778

申请日：2007-07-09

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden ,  Jason Hegener

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden ,  Jason Hegener

IPC分类号： A61B5/151

CPC分类号： A61B5/15146 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150221 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150427 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150755 ,  A61B5/15087 ,  A61B5/151 ,  A61B5/15113 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15176 ,  A61B5/15178 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/15194 ,  A61B5/157 ,  A61B5/6886 ,  A61M5/3295

摘要： A tissue penetrating system has a housing member, a plurality of penetrating members positioned in the housing member and a plurality of sample chambers. Each sample chamber is associated with a penetrating member. A tissue stabilizing member has a tissue interface surface configured to be applied to a tissue surface and provide for spontaneous flow of blood for sample capture. The tissue stabilizing member is coupled to the housing.

摘要翻译： 组织穿透系统具有壳体构件，定位在壳体构件中的多个穿透构件和多个样品室。 每个样品室与穿透构件相关联。 组织稳定构件具有构造成施加到组织表面并提供用于样品捕获的血液的自发流动的组织界面表面。 组织稳定构件联接到壳体。

公开(公告)号：US20070219462A1

公开(公告)日：2007-09-20

申请号：US11735599

申请日：2007-04-16

申请人： Barry Briggs ,  Dominique Freeman ,  Don Alden ,  Dirk Boecker

发明人： Barry Briggs ,  Dominique Freeman ,  Don Alden ,  Dirk Boecker

IPC分类号： A61B5/00

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/15019 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150824 ,  A61B5/150832 ,  A61B5/15087 ,  A61B5/150916 ,  A61B5/150954 ,  A61B5/151 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15174 ,  A61B5/15176 ,  A61B5/15184 ,  A61B5/15186 ,  A61B5/1519 ,  A61B5/15194 ,  A61B17/32093 ,  B01L3/5027 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet and a processor coupled to the drive force generator capable of changing the direction and magnitude of force exerted on the lancet during the lancing cycle. The driver further includes a human interface on the housing providing at least one output for communicating with the patient.

摘要翻译： 提供了一种刺血针驱动器，其中驾驶员在穿刺周期期间在柳叶刀上施加驱动力并且在组织部位上使用。 驱动器包括用于使柳叶刀前进的驱动力发生器和与驱动力发生器耦合的处理器，其能够改变在穿刺周期期间施加在刺血针上的力的方向和大小。 驱动器还包括在壳体上的人机接口，提供至少一个用于与患者通信的输出。

公开(公告)号：US20070213601A1

公开(公告)日：2007-09-13

申请号：US11689367

申请日：2007-03-21

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150251 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/15107 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/157 ,  A61B17/32093 ,  A61M2005/004 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

公开(公告)号：US20070185412A1

公开(公告)日：2007-08-09

申请号：US11549677

申请日：2006-10-16

申请人： Dirk Boecker ,  Don Alden ,  Dominique Freeman

发明人： Dirk Boecker ,  Don Alden ,  Dominique Freeman

IPC分类号： A61B5/00

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150251 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/15107 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/157 ,  A61B17/32093 ,  A61M2005/004 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： An improved penetrating tissue system is provided that reduces pain when penetrating tissue by providing controlled depth and velocity of penetration, stimulation and pressure to the targeted tissue without breaching a sterile enviromnent. The system has user interfaces, human interfaces and low volume sample chambers.

摘要翻译： 提供了一种改进的穿透组织系统，其通过在不破坏无菌环境的情况下通过向目标组织提供受控的穿透，刺激和压力的深度和速度来减少穿透组织时的疼痛。 该系统具有用户界面，人机接口和低容量采样室。

公开(公告)号：US20070173743A1

公开(公告)日：2007-07-26

申请号：US11674203

申请日：2007-02-13

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00

CPC分类号： G01N33/557 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150251 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/15087 ,  A61B5/15107 ,  A61B5/15123 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15178 ,  A61B5/157 ,  A61B17/32093 ,  A61M2005/004 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/0663 ,  B01L2300/18 ,  G01N33/4905

摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

公开(公告)号：US20070142748A1

公开(公告)日：2007-06-21

申请号：US11610612

申请日：2006-12-14

申请人： Ajay Deshmukh ,  Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Ajay Deshmukh ,  Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61B5/00

CPC分类号： A61B5/15178 ,  A61B5/150022 ,  A61B5/150061 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150175 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150251 ,  A61B5/150358 ,  A61B5/150427 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150755 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/150916 ,  A61B5/150954 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15128 ,  A61B5/15151 ,  A61B5/15153 ,  A61B5/15163 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15174 ,  A61B5/15184 ,  A61B5/1519 ,  A61B5/15194 ,  A61B5/157 ,  A61M2005/005 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/10 ,  B01L2200/147 ,  B01L2300/0663 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0605

摘要： A body fluid sampling system for use on a tissue site includes a drive force generator. A plurality of penetrating members are housed in a penetrating member housing. Each of penetrating member is configured to be coupled to the drive force generator. A plurality of analyte sensors are housed in an analyte sensor housing. Each analyte sensor is associated with a penetrating member. The analyte sensor housing is in a surrounding relationship to the penetrating member housing and positioned to provide that upon launch of a penetrating member, and penetration of a penetrating member at a skin surface, blood flows into the analyte sensor.

摘要翻译： 用于组织部位的体液取样系统包括驱动力发生器。 多个穿透构件容纳在穿透构件壳体中。 每个穿透构件被构造成联接到驱动力发生器。 多个分析物传感器容纳在分析物传感器外壳中。 每个分析物传感器与穿透构件相关联。 分析物传感器壳体与穿透构件壳体处于周围的关系中并且定位成提供在穿透构件发射时穿透构件在皮肤表面的穿透，血液流入分析物传感器。

公开(公告)号：US20070129650A1

公开(公告)日：2007-06-07

申请号：US10558865

申请日：2004-06-01

申请人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

发明人： Dominique Freeman ,  Dirk Boecker ,  Don Alden

IPC分类号： A61N1/30 ,  A61M1/00 ,  A61B5/00 ,  A61M31/00 ,  A61M25/00

CPC分类号： A61B5/157 ,  A61B5/150022 ,  A61B5/150152 ,  A61B5/150167 ,  A61B5/150183 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150824 ,  A61B5/150954 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/1513 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15169 ,  A61B5/15171 ,  A61B5/15176 ,  A61B5/15182 ,  A61B5/7445 ,  A61M5/20 ,  A61M5/282 ,  A61M5/3291 ,  A61M2005/004 ,  A61M2005/005 ,  A61M2005/206 ,  A61N2/002

摘要： A device is provided for fluid delivery. The device comprises a cartridge having a plurality of cavities and a plurality of penetrating members. The plurality of penetrating members are each at least partially contained in cavities of the cartridge wherein the penetrating members are slidably movable to extend outward from openings on said cartridge to penetrate tissue. Each of the penetrating members comprises a needle with a lumen coupled to a canister containing a material to be injected.

摘要翻译： 提供了用于流体输送的装置。 该装置包括具有多个空腔和多个穿透构件的盒。 多个穿透构件各自至少部分地容纳在盒的空腔中，其中穿透构件可滑动地移动以从所述盒上的开口向外延伸以穿透组织。 每个穿透构件包括具有与容纳待注射材料的罐连接的腔的针。