公开(公告)号：US20180296331A1

公开(公告)日：2018-10-18

申请号：US15946604

申请日：2018-04-05

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. A clasp is attached to each of the paddles. Each clasp has a fixed arm attached to the paddle and a moveable arm having a barbed portion. A hinge portion connects the fixed arm to the moveable arm. The device does not include catch points when the paddles are in the open position and the clasps are in a closed condition.

公开(公告)号：US20180296326A1

公开(公告)日：2018-10-18

申请号：US15909803

申请日：2018-03-01

Applicant: Edwards Lifesciences Corporation

Inventor： Eric Robert Dixon ,  Jensen Chen ,  Guillermo W. Moratorio ,  Hengchu Cao ,  Douglas Thomas Dominick ,  Sergio Delgado ,  Lauren R. Freschauf

IPC: A61F2/24

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are extendable from a folded closed position to an open position. The clasps each have a fixed arm and a plurality of moveable arms each having a barbed portion. A plurality of hinge portions connect the moveable arms to the fixed arm.

公开(公告)号：US09980816B2

公开(公告)日：2018-05-29

申请号：US14663101

申请日：2015-03-19

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Brian S. Conklin ,  Paul A. Schmidt ,  Grace M. Kim ,  James A. Davidson ,  Hoa T. Tran ,  Kristy L. Tam

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415

Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions. Examples of delivery systems and methods for deploying the valves exhibit reduced patient trauma.

公开(公告)号：US20170119523A1

公开(公告)日：2017-05-04

申请号：US15403423

申请日：2017-01-11

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Wei Sun

IPC: A61F2/24 ,  A61L27/36

CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2210/0014 ,  A61F2220/0075 ,  A61L27/3625

Abstract: A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. The commissure posts angle outward in a neutral state to widen the outflow orifice area. Also, the leaflets are designed to fit within the support frame and expand outward in a valve open state without creating a shelf or belly that would restrict flow.

公开(公告)号：US20160166248A1

公开(公告)日：2016-06-16

申请号：US14965323

申请日：2015-12-10

Applicant: Edwards Lifesciences Corporation

Inventor： Derek Dee Deville ,  Kevin W. Smith ,  Michael Walter Kirk ,  Carlos Rivera ,  George Nunez ,  Thomas O. Bales, JR. ,  Korey Kline ,  Matthew A. Palmer ,  M. Sean McBrayer ,  Richard Cartledge ,  Max Pierre Mendez ,  Hengchu Cao ,  Anthony Peter Carcia ,  Kevin Dang ,  Carey Hendsbee ,  Brent K. Hoffman ,  Brian R. Jacobs ,  Mohammad Jafari ,  Brian Janish ,  Jeffrey L. Mahoney ,  Raffaele Mazzei ,  Manouchehr A. Miraki ,  Ryan Moehle ,  Jeremiah Morgan ,  Michael C. Murad ,  Travis Zenyo Oba ,  Ralph Schneider ,  Fabian Daniel Schroeder ,  Tyler Douglas Smith ,  Ming H. Wu

IPC: A61B17/04

CPC classification number: A61B17/0485 ,  A61B17/0467 ,  A61B17/0487 ,  A61B2017/00017 ,  A61B2017/00119 ,  A61B2017/00349 ,  A61B2017/00358 ,  A61B2017/00398 ,  A61B2017/00477 ,  A61B2017/00734 ,  A61B2017/00876 ,  A61B2017/00902 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2090/064 ,  A61B2090/0807 ,  A61B2090/309 ,  A61B2090/3937

Abstract: A multiple-fire securing device includes a hollow outer shaft, a reloader, a reloader movement assembly, a rail, and securing structures each defining an inner securing orifice. The reloader longitudinally moves within the outer shaft and has a distal end shaped to temporarily contact one of the securing structures. The rail is disposed within the reloader and has an installing location. The securing structures are disposed on the rail. The reloader movement assembly moves the reloader longitudinally in a distal direction to deliver a first securing structure to the installing location from a first proximal position and moves the reloader proximally away from the installing location without the first securing structure to a position in which the distal end of the reloader temporarily contacts a second one of the securing structures. The second and successive securing structures are moved one at a time to the installing location.

Abstract translation: 多重火焰固定装置包括中空的外轴，重新装载机，重装机运动组件，轨道和固定结构，每个限定内固定孔。 重新装载机在外轴内纵向移动并且具有成形为临时接触其中一个固定结构的远端。 轨道设置在重新装载机内并具有安装位置。 固定结构设置在轨道上。 重新装载机构移动组件沿远侧方向纵向运动重新装载机，以将第一固定结构从第一近端位置传送到安装位置，并将重新装载机向近侧移动远离安装位置而不用第一固定结构移动到远端 的重新加载器临时接触第二个固定结构。 第二和连续的固定结构一次一个地移动到安装位置。

公开(公告)号：US20150230922A1

公开(公告)日：2015-08-20

申请号：US14663101

申请日：2015-03-19

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Brian S. Conklin ,  Paul A. Schmidt ,  Grace M. Kim ,  James A. Davidson ,  Hoa T. Tran ,  Kristy L. Tam

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415

Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions. Examples of delivery systems and methods for deploying the valves exhibit reduced patient trauma.

Abstract translation: 公开的假体瓣膜可以包括构造成将瓣膜固定到植入部位的缝合环。 一些公开的阀包括具有中性构型和折叠展开构型的弹性可折叠框架。 当从折叠部署配置释放时，一些公开的框架可以自扩展到中立配置。 折叠所公开的阀可以方便地进入缝合环，例如用于将瓣膜固定到植入部位，以及通过相对较小的手术切口插入瓣膜。 用于部署阀的递送系统和方法的示例表现出减少的患者创伤。

公开(公告)号：US20140031864A1

公开(公告)日：2014-01-30

申请号：US13938071

申请日：2013-07-09

Applicant: Edwards Lifesciences Corporation

Inventor： Mohammad Jafari ,  Ming H. Wu ,  Hengchu Cao ,  Ralph Schneider

IPC: A61B17/04

CPC classification number: A61B17/0401 ,  A61B17/0487 ,  A61B17/0642 ,  A61B2017/0404 ,  A61B2017/0406 ,  A61B2017/0419 ,  A61B2017/042 ,  A61B2017/0437 ,  A61B2017/0438 ,  A61B2017/0446 ,  A61B2017/0448 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/049 ,  A61F2/0811 ,  A61F2/2448 ,  B65D33/1625 ,  Y10T24/155 ,  Y10T24/44923

Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.

Abstract translation: 这里公开了缝合线固定装置的示例性实施例，其代替在缝合线中结扎的需要。 一些实施例包括环形外体和从外体向内延伸的一个或多个缝合线接合片。 该装置可以包括超弹性和/或形状记忆材料，并且具有大致平面的初始构型。 缝合线接合部分可以在平面外成形为活动构型，外部主体被压缩，并且翼片彼此互锁。 该设备可以在变形的配置中进行热定形。 互锁的舌片在通过它们之间的缝合线上施加夹紧力，其限制缝合线在一个纵向方向上滑动通过开口。