公开(公告)号：US09278222B2

公开(公告)日：2016-03-08

申请号：US12501282

申请日：2009-07-10

Applicant: James R. Thacker ,  Michael Moffitt ,  Kerry Bradley ,  David K. L. Peterson

Inventor： James R. Thacker ,  Michael Moffitt ,  Kerry Bradley ,  David K. L. Peterson

IPC: A61N1/36 ,  A61N1/372 ,  G06F19/00

CPC classification number: A61N1/37264 ,  A61N1/36071 ,  A61N1/36146 ,  A61N1/3615 ,  A61N1/36167 ,  A61N1/36185 ,  A61N1/37247 ,  G06F19/00 ,  G16H40/63

Abstract: A method, computer medium, and system for programming a controller is provided. The controller controls electrical stimulation energy output to electrodes, and stores a set of programmed stimulation parameters associated with the electrodes. The programmed stimulation parameter set is compared with sets of reference stimulation parameters, each of the reference sets of stimulation parameters being associated with the electrodes. If an identical match is determined between the programmed stimulation parameter set and any one of the reference stimulation parameter sets exists based on the comparison, the identically matched stimulation parameter set is selected as an initial stimulation parameter set. If an identical match does not exist, a best between the programmed stimulation parameter set and the reference stimulation parameter sets is determined and selected as the initial stimulation parameter set. The controller is then programmed with a new set of programmable stimulation parameters based on the initial stimulation parameter set.

Abstract translation: 提供了一种用于编程控制器的方法，计算机介质和系统。 控制器控制对电极的电刺激能量输出，并且存储与电极相关联的一组编程的刺激参数。 将编程的刺激参数集与参考刺激参数的集合进行比较，每个参考组的刺激参数与电极相关联。 如果在编程的刺激参数集之间确定相同的匹配，并且基于比较存在参考刺激参数集中的任一个，则选择相同匹配的刺激参数集作为初始刺激参数集。 如果不存在相同的匹配，则确定编程的刺激参数集和参考刺激参数集之间的最佳值，并将其选为初始刺激参数集。 然后基于初始刺激参数集，控制器用一组新的可编程刺激参数进行编程。

公开(公告)号：US08712533B2

公开(公告)日：2014-04-29

申请号：US12765747

申请日：2010-04-22

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/18 ,  A61N1/36 ,  A61N1/06 ,  A61N1/05

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US08359102B2

公开(公告)日：2013-01-22

申请号：US13446970

申请日：2012-04-13

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/18

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US20130013044A1

公开(公告)日：2013-01-10

申请号：US13620138

申请日：2012-09-14

Applicant: James R. Thacker ,  Michael S. Colvin ,  David K.L. Peterson ,  James P. McGivern

Inventor： James R. Thacker ,  Michael S. Colvin ,  David K.L. Peterson ,  James P. McGivern

IPC: A61N1/05

CPC classification number: A61N1/0558 ,  A61M25/1002 ,  A61M25/1011

Abstract: An implantable lead having at least one electrode contact at or near its distal end prevents undesirable movement of the electrode contact from its initial implant location. One embodiment relates to a spinal cord stimulation (SCS) lead. A first injectable material is injected into the dura space to mechanically position the electrode array with respect to the spinal cord. Conjunctively for use with adhesives, or alternatively for use instead of the adhesives, a balloon may be positioned on the electrode lead array. The balloon is filled with air, liquid or a compliant material. When inflated, the balloon stabilizes the lead with respect to the spinal cord and holds the lead in place. An elastic aspect of the balloon serves as an internal contained relief valve to limit the pressure the balloon may place on the surrounding tissues when the epidural space is constrained.

Abstract translation: 具有在其远端处或其远端处具有至少一个电极接触的可植入引线防止电极接触件从其初始植入位置的不期望的移动。 一个实施方案涉及脊髓刺激（SCS）引线。 将第一可注射材料注入硬脑膜空间以相对于脊髓机械地定位电极阵列。 结合使用粘合剂，或代替粘合剂代替使用，球囊可以位于电极引线阵列上。 气球充满空气，液体或柔顺材料。 当膨胀时，气囊相对于脊髓稳定铅，并将铅保持在适当位置。 气囊的弹性方面用作内部包含的安全阀，以限制当硬膜外腔被约束时球囊可能在周围组织上的压力。

公开(公告)号：US20120203303A1

公开(公告)日：2012-08-09

申请号：US13446970

申请日：2012-04-13

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/34

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

公开(公告)号：US08170675B2

公开(公告)日：2012-05-01

申请号：US13245450

申请日：2011-09-26

Applicant: Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

Inventor： Konstantinos Alataris ,  Andre B. Walker ,  Jon Parker ,  Yougandh Chitre ,  Sangsoo Wesley Park ,  James R. Thacker

IPC: A61N1/18

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/06 ,  A61N1/36021 ,  A61N1/3605 ,  A61N1/36157 ,  A61N1/36164 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N1/36182 ,  A61N1/37235 ,  A61N1/37241 ,  A61N1/37247 ,  A61N1/37264 ,  A61N1/3787

Abstract: Selective high-frequency spinal chord modulation for inhibiting pain with reduced side affects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal chord region to address low back pain without creating unwanted sensory and/or motor side affects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

Abstract translation: 公开了选择性高频脊髓调制，用于抑制疼痛，减少副作用和相关系统和方法。 在特定实施例中，可以将大约1.5KHz至大约50KHz范围内的高频调制施加到患者的脊弦区域以解决腰背痛而不产生不想要的感觉和/或运动副作用。 在其他实施例中，根据类似参数的调制可以应用于其他脊柱或周边位置以解决其他指示。

公开(公告)号：US08065013B2

公开(公告)日：2011-11-22

申请号：US11746405

申请日：2007-05-09

Applicant: Kerry Bradley ,  James R. Thacker ,  Carla M. Woods ,  John D. King

Inventor： Kerry Bradley ,  James R. Thacker ,  Carla M. Woods ,  John D. King

IPC: A61N1/34

CPC classification number: A61N1/36071 ,  A61N1/0551 ,  Y10S128/92

Abstract: A method of transitioning stimulation energy (e.g., electrical stimulation pulses) between a plurality of electrodes implanted within a patient is provided. The method comprises selecting a plurality of stimulation output values (e.g., electrical current amplitude values) for each of the electrodes. The method further comprises selecting a plurality of different modification values for at least one of the electrodes, respectively multiplying the stimulation output values and the modification values to determine modified stimulation output values for the electrode(s), which may optionally be stored in a steering table, and incrementally transitioning the stimulation energy to or from the electrode(s) in accordance with the modified stimulation output values. The modified stimulation output values are stored in a steering table. The modification values may be selected in a manner that maintains paresthesia when transitioning the stimulation energy between the electrodes.

Abstract translation: 提供了在植入患者体内的多个电极之间转换刺激能量（例如，电刺激脉冲）的方法。 该方法包括为每个电极选择多个刺激输出值（例如，电流振幅值）。 该方法还包括为至少一个电极选择多个不同的修改值，分别乘以刺激输出值和修改值，以确定电极的修改的刺激输出值，其可以可选地存储在转向 表，并且根据修改的刺激输出值逐渐地将刺激能量转移到电极或从电极移动。 经修改的刺激输出值存储在转向表中。 可以以在电极之间转换刺激能量时保持感觉异常的方式来选择修饰值。

公开(公告)号：US08036747B2

公开(公告)日：2011-10-11

申请号：US12506827

申请日：2009-07-21

Applicant: James R. Thacker ,  John D. H. King ,  Kerry Bradley

Inventor： James R. Thacker ,  John D. H. King ,  Kerry Bradley

IPC: A61N1/37

CPC classification number: A61N1/36071 ,  A61N1/0551

Abstract: A system and method for rapidly switching stimulation parameters of a Spinal Cord Stimulation (SCS) system increases the number of stimulation parameter sets that may be tested during a fitting procedure, or alternatively, reduces the time required for the fitting procedure. The switching method comprises selecting a new stimulation parameter set, and setting the initial stimulation levels to levels at or just below an estimated perception threshold of the patient. The estimated perception level is based on previous stimulation results. The stimulation level is then increased to determine a minimum stimulation level for effective stimulation, and/or an optimal stimulation level, and/or a maximum stimulation level, based on patient perception.

Abstract translation: 用于快速切换脊髓刺激（SCS）系统的刺激参数的系统和方法增加了在拟合过程期间可以测试的刺激参数集的数量，或者替代地减少了拟合过程所需的时间。 切换方法包括选择新的刺激参数集合，以及将初始刺激水平设置为等于或低于估计的患者感知阈值的水平。 估计的感知水平是基于以前的刺激结果。 然后根据患者的感知，增加刺激水平以确定有效刺激的最小刺激水平和/或最佳刺激水平和/或最大刺激水平。

公开(公告)号：US20110060387A1

公开(公告)日：2011-03-10

申请号：US12946574

申请日：2010-11-15

Applicant: John D.H. King ,  James R. Thacker

Inventor： John D.H. King ,  James R. Thacker

IPC: A61N1/36

CPC classification number: A61N1/36139 ,  A61N1/08 ,  A61N1/36071 ,  A61N1/3615

Abstract: A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.

公开(公告)号：US07856277B1

公开(公告)日：2010-12-21

申请号：US11464137

申请日：2006-08-11

Applicant: James R. Thacker ,  Michael S Colvin ,  David K. L. Peterson ,  James P. McGivern

Inventor： James R. Thacker ,  Michael S Colvin ,  David K. L. Peterson ,  James P. McGivern

IPC: A61N1/372

CPC classification number: A61N1/0558 ,  A61M25/10

Abstract: An implantable lead having at least one electrode contact at or near its distal end prevents undesirable movement of the electrode contact from its initial implant location. One embodiment relates to a spinal cord stimulation (SCS) lead. A first injectable material is injected into the dura space to mechanically position the electrode array with respect to the spinal cord. Conjunctively for use with adhesives, or alternatively for use instead of the adhesives, a balloon may be positioned on the electrode lead array. The balloon is filled with air, liquid or a compliant material. When inflated, the balloon stabilizes the lead with respect to the spinal cord and holds the lead in place. An elastic aspect of the balloon serves as a contained relief valve to limit the pressure the balloon may place on the surrounding tissues when the epidural space is constrained.

Abstract translation: 具有在其远端处或其远端处具有至少一个电极接触的可植入引线防止电极接触件从其初始植入位置的不期望的移动。 一个实施方案涉及脊髓刺激（SCS）引线。 将第一可注射材料注入硬脑膜空间以相对于脊髓机械地定位电极阵列。 结合使用粘合剂，或代替粘合剂代替使用，球囊可以位于电极引线阵列上。 气球充满空气，液体或柔顺材料。 当膨胀时，气囊相对于脊髓稳定铅，并将铅保持在适当位置。 气囊的弹性方面用作包含的安全阀，以限制当硬膜外腔被约束时球囊可能在周围组织上的压力。