公开(公告)号：US5632994A

公开(公告)日：1997-05-27

申请号：US410804

申请日：1995-03-27

申请人： John C. Reed ,  Takaaki Sato

发明人： John C. Reed ,  Takaaki Sato

IPC分类号： C12N15/09 ,  A61K38/00 ,  A61K45/00 ,  A61K48/00 ,  C07K14/47 ,  C12N5/10 ,  C12N9/16 ,  C12N15/00 ,  C12N15/10 ,  C12N15/55 ,  C12P21/08 ,  C12Q1/04 ,  C12Q1/68 ,  C12R1/91 ,  A61K39/00 ,  C07K16/00 ,  G01N33/53

CPC分类号： C07K14/4747 ,  C12N15/1055 ,  C12N9/16 ,  C12Q1/6897 ,  A61K38/00

摘要： The present invention provides mammalian protein tyrosine phosphatases, human PTP-BAS type 4, human PTP-BAS type 5a and mouse PTP-BAS type 5b, each of which is a Fas-associated protein (FAP), nucleic acid molecules encoding a PTP-BAS type 4 or a PTP-BAS type 5 and antibodies specific for a PTP-BAS type 4 or for a PTP-BAS type 5. The invention also provides methods for identifying FAP's, which can associate with Fas and can modulate apoptosis. The invention also provides screening assays for identifying an agent that can effectively alter the association of a FAP with Fas and, therefore, can increase or decrease the level of apoptosis in a cell. The invention further provides methods of modulating apoptosis in a cell by introducing into the cell a nucleic acid molecule encoding a PTP-BAS or fragment of a PTP-BAS or an antisense nucleotide sequence, which is complementary to a portion of a nucleic acid molecule encoding a PTP-BAS. The invention also provides a method of using a reagent that can specifically bind to a FAP to diagnose a pathology that is characterized by an increased or decreased level of apoptosis in a cell. The invention also provides methods of modulating apoptosis in a cell by contacting the cell with an agent that effectively alters the association of a FAP and Fas in a cell or alters the activity of a FAP in a cell.

摘要翻译： 本发明提供哺乳动物蛋白酪氨酸磷酸酶，人PTP-BAS型4，人PTP-BAS型5a和小鼠PTP-BAS型5b，其各自是Fas相关蛋白（FAP），编码PTP- BAS型4或PTP-BAS型5和PTP-BAS型4或PTP-BAS型5特异性抗体。本发明还提供鉴定FAP的方法，其可与Fas结合并可调节细胞凋亡。 本发明还提供用于鉴定能够有效改变FAP与Fas的缔合的试剂的筛选测定，因此可以增加或降低细胞凋亡水平。 本发明还提供了通过向细胞中引入编码PTP-BAS或PTP-BAS或反义核苷酸序列片段的核酸分子来调节细胞凋亡的方法，所述核酸分子与编码的核酸分子的一部分互补 一个PTP-BAS。 本发明还提供了使用能够特异性结合FAP的试剂来诊断细胞凋亡水平升高或降低的病理学的方法。 本发明还提供了通过使细胞与有效改变细胞中FAP和Fas的缔合的试剂接触而改变细胞凋亡的方法或改变细胞中FAP的活性的方法。

公开(公告)号：US08542835B2

公开(公告)日：2013-09-24

申请号：US12366384

申请日：2009-02-05

申请人： Motoshi Tamura ,  Mutsumaru Miki ,  Akiko Okamoto ,  Kenya Kusunose ,  Akihiro Uchikoshi ,  Daisuke Igarashi ,  Katsuhiko Yamagata ,  Takaaki Sato ,  Junichiro Hagiwara ,  Yasuyuki Watanabe ,  Takuya Hamajima ,  Masafumi Hata ,  Nobutaka Ishikawa ,  Yoshiyuki Yasuda ,  Kazufumi Yunoki ,  Nobuhide Uchiyama

发明人： Motoshi Tamura ,  Mutsumaru Miki ,  Akiko Okamoto ,  Kenya Kusunose ,  Akihiro Uchikoshi ,  Daisuke Igarashi ,  Katsuhiko Yamagata ,  Takaaki Sato ,  Junichiro Hagiwara ,  Yasuyuki Watanabe ,  Takuya Hamajima ,  Masafumi Hata ,  Nobutaka Ishikawa ,  Yoshiyuki Yasuda ,  Kazufumi Yunoki ,  Nobuhide Uchiyama

IPC分类号： H04L29/06

CPC分类号： H04B7/022 ,  H04W12/02 ,  H04W12/06 ,  H04W36/08 ,  H04W36/18 ,  H04W52/04 ,  H04W52/12 ,  H04W80/04 ,  H04W84/042 ,  H04W88/06 ,  H04W88/12

摘要： When a network pages the temporary user mobile identifier of a mobile station, the mobile station sends a response to the network. Next, the network checks the authenticity of the user using a ciphering key, corresponding to the temporary user mobile identifier and a random number. If the temporary user mobile identifier is authenticated, a normal incoming call acceptance procedure is executed. If the mobile station is authenticated although the temporary user mobile identifier is wrong, the network reassigns a new temporary user mobile identifier to the mobile station and stops the current communication. In communication, the network and the mobile station mutually notify encipherment-onset time and negotiate about encipherment manner with each other. In addition, diversity handover is commenced upon a call attempt. Furthermore, if a branch replacement is necessary, the current branch is replaced by new branches capable of executing the diversity handover. Additionally, when a new call occurs to or from the mobile station capable of treating a plurality of calls simultaneously, the mobile station uses the same branch structure and the same communication frequency band for all of calls. Additionally, when a new call occurs to or from the mobile station capable of treating a plurality of calls simultaneously, a branch structure and a communication frequency band, which can continue all of the calls, are selected and used. Therefore, the mobile communications system is suitable for transmission of various sorts of data in accordance with the development of multimedia.

公开(公告)号：US08542651B2

公开(公告)日：2013-09-24

申请号：US12515127

申请日：2007-11-16

申请人： Masafumi Masuda ,  Toyohiro Abe ,  Takaaki Sato ,  Katsuhiko Yamagata

发明人： Masafumi Masuda ,  Toyohiro Abe ,  Takaaki Sato ,  Katsuhiko Yamagata

IPC分类号： H04W4/00

CPC分类号： H04W8/26 ,  H04W36/02 ,  H04W80/04 ,  H04W92/12

摘要： In a communication system of a subscriber extension line system, there is provided a communication controller whereby the load of an unnecessary process to be applied on a communication controller relating to a destination of a mobile telephone is eliminated and the processing efficiency for communication control is enhanced. In a D-RNC which controls the communication of the mobile telephone and which is commonly connected with an S-RNC, the mobile telephone moves while maintaining the communication with the S-RNC. When the mobile telephone enters a cell relating to the D-RNC, the control data is transmitted or received between the S-RNC and the node for managing the mobile telephone. There are also provided: an IP address/UDP port number for RNSAP, reading/setting section 316 for acquiring an IP address identifying the S-RNC and an IP address identifying the node; an IP address/UDP port number for NBAP, reading/setting section 315; and an IP address/UDP port number exchange section 314 for notifying the other side of the S-RNC and the node of the acquired IP addresses, respectively. This allows a direct communication between the S-RNC and the node.

摘要翻译： 在用户分机线路系统的通信系统中，提供了一种通信控制器，其中消除了应用于与移动电话的目的地有关的通信控制器的不必要的处理的负担，并且提高了通信控制的处理效率 。 在控制移动电话的通信并且与S-RNC共同连接的D-RNC中，移动电话在保持与S-RNC的通信的同时移动。 当移动电话进入与D-RNC相关的小区时，在S-RNC和用于管理移动电话的节点之间发送或接收控制数据。 还提供：用于RNSAP的IP地址/ UDP端口号，用于获取标识S-RNC的IP地址的读取/设置部分316和标识该节点的IP地址; NBAP的IP地址/ UDP端口号，读取/设置部分315; 以及IP地址/ UDP端口号交换部314，用于分别通知S-RNC的另一侧和所获取的IP地址的节点。 这允许S-RNC和节点之间的直接通信。

公开(公告)号：US20130112335A1

公开(公告)日：2013-05-09

申请号：US13808983

申请日：2011-06-03

申请人： Hidetaka Hattori ,  Hideki Horizono ,  Takaaki Sato ,  Tadashi Yazaki

发明人： Hidetaka Hattori ,  Hideki Horizono ,  Takaaki Sato ,  Tadashi Yazaki

IPC分类号： B32B37/10

CPC分类号： B32B37/1054 ,  B29C43/12 ,  B29C43/203 ,  B29C43/3642 ,  B29C70/342 ,  B29C70/44 ,  B29C70/46 ,  B29C2043/3644 ,  B29K2105/0872

摘要： A method for manufacturing a resin-based composite material includes: a stage in which prepregs are stacked on a jig; a stage in which the stacked prepregs and the jig are covered and pressurized heat treatment is applied thereto to form a first semi-molded article and a second semi-molded article; a stage in which board thicknesses of the first semi-molded article and the second semi-molded article are measured, a stage in which the number of additional plies is determined based on the measured board thicknesses, a desired board thickness of the resin-based composite material, and physical properties of the additional plies; and a stage in which a layered product is formed by stacking the predetermined number of additional plies between the first semi-molded article and the second semi-molded article, the layered product and the jig are covered with a bagging material, and pressurized heat treatment is applied thereto.

摘要翻译： 树脂类复合材料的制造方法包括：将预浸料堆叠在夹具上的阶段; 堆叠的预浸料坯和夹具被覆盖并进行加压热处理以形成第一半成型制品和第二半成型制品的阶段; 测量第一半模制品和第二半模制品的板厚度的阶段，基于所测量的板厚确定附加层数的阶段，树脂基板的期望板厚度 复合材料和附加层的物理性质; 以及通过在第一半模制品和第二半模制品之间堆叠预定数量的附加层而形成层压产品的阶段，层叠产品和夹具用袋装材料覆盖，并且进行加压热处理 应用于此。

公开(公告)号：US20130023270A1

公开(公告)日：2013-01-24

申请号：US13574140

申请日：2011-01-19

申请人： Hiroyuki Hosono ,  Takaaki Sato ,  Takeshi Terayama ,  Takeshi Okamoto

发明人： Hiroyuki Hosono ,  Takaaki Sato ,  Takeshi Terayama ,  Takeshi Okamoto

IPC分类号： H04W36/00

CPC分类号： H04W48/08 ,  H04W36/08 ,  H04W48/20 ,  H04W68/00 ,  H04W88/08

摘要： A mobile communication system 100 includes a radio base station 20 for a specific cell configured to manage a specific cell to which any one of a plurality of frequencies allocated to a public cell is allocated. The radio base station 20 for a specific cell notifies guidance notification leading cell reselection from the public cell to the specific cell by using the remaining frequencies other than the frequency allocated to the specific cell.

摘要翻译： 移动通信系统100包括用于特定小区的无线基站20，所述特定小区被配置为管理分配给公共小区的多个频率中的任何一个的特定小区。 用于特定小区的无线电基站20通过使用除了分配给特定小区的频率之外的其余频率将通知引导小区重选从公共小区重新通知给特定小区。

公开(公告)号：US08353130B2

公开(公告)日：2013-01-15

申请号：US13064119

申请日：2011-03-07

申请人： Masahito Fukuta ,  Tatsushi Goto ,  Masatoshi Hotta ,  Takaaki Sato

发明人： Masahito Fukuta ,  Tatsushi Goto ,  Masatoshi Hotta ,  Takaaki Sato

IPC分类号： B60J10/08

CPC分类号： B60J10/24 ,  B60J10/15 ,  B60J10/16 ,  B60J10/30 ,  B60J10/36 ,  B60J10/80

摘要： A door weather strip includes an attaching base part that is attached along an outer periphery of a door frame and a hollow seal part that is extended in an outer peripheral direction of a door from the attaching base part. The attaching base part 11 includes a base bottom part, a vehicle inner side wall part and a vehicle outer side wall part and a partition wall. Both the attaching base part and the seal part are made of the same EPDM sponge rubber material by an extrusion process. The door weather strip satisfies conditions that a specific gravity is 0.36 or higher and 0.44 or lower, a low stretch stress is 200 kPa or higher and 230 kPa or lower and an average foaming cell diameter is 180 μm or larger and 220 μm or smaller.

摘要翻译： 门防风条包括沿着门框的外周附着的安装基部和从安装基部在门的外周方向上延伸的中空密封部。 安装基部11包括基部底部，车辆内侧壁部和车辆外侧壁部以及隔壁。 连接基部和密封部均通过挤出工艺由相同的EPDM海绵橡胶材料制成。 门耐候条满足比重为0.36以上且0.44以下，低拉伸应力为200kPa以上且230kPa以下且平均发泡细胞直径为180μm以上且220μm以下的条件。

公开(公告)号：US20120155392A1

公开(公告)日：2012-06-21

申请号：US13382073

申请日：2010-07-02

申请人： Takahiro Hayashi ,  Masafumi Masuda ,  Hidehiro Ando ,  Takaaki Sato ,  Yoshiyuki Yasuda

发明人： Takahiro Hayashi ,  Masafumi Masuda ,  Hidehiro Ando ,  Takaaki Sato ,  Yoshiyuki Yasuda

IPC分类号： H04W4/00

CPC分类号： H04L69/324 ,  H04L69/18 ,  H04W28/06 ,  H04W76/20

摘要： Disclosed is a communication method for switching between a first connection state, in which a data unit is transmitted in a first size, and a second connection state, in which a data unit is transmitted in a second size which is larger than the first size. The communication method comprises a step of maintaining the size of a data unit at the first size in a case where there is a transition from the first connection state to the second connection state after there had been a transition from the second connection state to the first connection state.

摘要翻译： 公开了一种通信方法，用于在以第一大小发送数据单元的第一连接状态和第二连接状态之间进行切换，其中数据单元以大于第一尺寸的第二尺寸传输。 通信方法包括以下步骤：在从第二连接状态到第一连接状态的转变之间存在从第一连接状态到第二连接状态的转变的情况下，将数据单元的尺寸维持在第一尺寸的步骤 连接状态。

公开(公告)号：USRE43296E1

公开(公告)日：2012-04-03

申请号：US12572065

申请日：2009-10-01

申请人： Tomoyuki Ohtani ,  Motoshi Tamura ,  Takaaki Sato

发明人： Tomoyuki Ohtani ,  Motoshi Tamura ,  Takaaki Sato

IPC分类号： H04M1/00

摘要： A branch candidate selecting method by a mobile station and a diversity handover control method on a network side in DHO performance are provided which consider a maximum cable branch number and maximum radio branch number of the mobile station, when the mobile station detects the plurality of addition branch candidates and deletion branch candidates. The mobile station inserts a plurality of addition branch candidates and deletion branch candidates, that is, all the DHO candidates into one handover trigger signal, and notifies the network. The addition branch candidates are put into addition information parameters in the handover trigger signal, and the deletion branch candidates are put into deletion information parameters. To simplify processing on the network side, the network side separates the addition branch candidates from the deletion branch candidates, and carries out sequential processing of them independently.

摘要翻译： 提供了一种移动台的分支候选选择方法和DHO性能的网络侧分集切换控制方法，当移动台检测到多个加法时，考虑移动台的最大电缆分支号和最大无线分支号 分支候选人和删除分支候选人。 移动台将多个相加分支候选和删除分支候选，即所有DHO候选都插入到一个切换触发信号中，并通知网络。 在切换触发信号中添加分支候补被添加到附加信息参数中，并且删除分支候选被放入删除信息参数中。 为了简化网络侧的处理，网络侧将删除分支候选的加法分支候补分离，并进行它们的连续处理。

公开(公告)号：US20110032905A1

公开(公告)日：2011-02-10

申请号：US12911224

申请日：2010-10-25

申请人： Tomoyuki Ohtani ,  Motoshi Tamura ,  Takaaki Sato

发明人： Tomoyuki Ohtani ,  Motoshi Tamura ,  Takaaki Sato

IPC分类号： H04W4/00

CPC分类号： H04W36/18 ,  H04B7/022 ,  H04B7/0491 ,  H04W36/08 ,  H04W36/28 ,  H04W36/30 ,  H04W92/04 ,  H04W92/20

摘要： A mobile station for communicating with base stations simultaneously in diversity handover. The mobile station monitors radio condition quality corresponding to a plurality of branches, selects one or more addition branch candidates based on the monitored radio condition quality. The mobile station arranges the addition branch candidates in order of the monitored radio condition quality; notifies a center of information on said plurality of branches including said addition branch candidates, the addition branch candidates being notified in the arranged order. Alternatively, the mobile station obtains a relative value of each of the addition branch candidates indicative of order of precedence to be used for the diversity handover based on the monitored radio condition quality of said addition branch candidates; and notifies a center of information on said plurality of branches including said addition branch candidates and their relative values.

摘要翻译： 移动台，用于在分集切换中同时与基站进行通信。 移动站监视与多个分支相对应的无线条件质量，基于所监视的无线电条件质量来选择一个或多个添加分支候选。 移动台以监视的无线电条件质量的顺序排列加法分支候选; 向所述多个分支的信息的中心通知包括所述相加分支候选的信息，所述加法分支候选被按顺序通知。 或者，移动站基于所述加法分支候选的被监视的无线条件质量，获得表示要用于分集越区切换的优先顺序的各加法分支候选的相对值; 并且向中心通知所述多个分支的信息，包括所述相加分支候选及其相对值。

公开(公告)号：US07873014B2

公开(公告)日：2011-01-18

申请号：US11929759

申请日：2007-10-30

申请人： Tomoyuki Ohtani ,  Motoshi Tamura ,  Takaaki Sato

发明人： Tomoyuki Ohtani ,  Motoshi Tamura ,  Takaaki Sato

IPC分类号： H04W4/00

CPC分类号： H04W36/18 ,  H04B7/022 ,  H04B7/0491 ,  H04W36/08 ,  H04W36/28 ,  H04W36/30 ,  H04W92/04 ,  H04W92/20

摘要： A handover method for controlling communication between a mobile station and base station(s) in a wireless communication system. The method includes measuring signal qualities transmitted from the base station(s), the measured signal qualities including a measured quality of a signal received from a certain base station; identifying the base station as an addition candidate based on the measured quality exceeding an addition threshold; thereafter detecting that the measured quality of the signal received from the addition candidate has further exceeded an active threshold which is greater than the addition threshold. The active threshold is determined in accordance with a quality of a signal transmitted from one or more active base stations. In response, the base stations are notified of information about the addition candidate; and a handover process is performed on the bases on this information.

摘要翻译： 一种用于控制无线通信系统中的移动站和基站之间的通信的切换方法。 该方法包括测量从基站发送的信号质量，所测量的信号质量包括从某个基站接收的信号的测量质量; 基于超过添加阈值的测量质量将基站识别为添加候选; 然后检测从加法候选者接收的信号的测量质量进一步超过大于加法阈值的有效阈值。 根据从一个或多个有源基站发送的信号的质量来确定活动阈值。 作为响应，通知基站关于添加候选者的信息; 并且基于该信息执行切换处理。