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公开(公告)号:US20150067747A1
公开(公告)日:2015-03-05
申请号:US14391680
申请日:2012-04-13
申请人: Michael Huber
发明人: Michael Huber
IPC分类号: H04N21/235 , H04N21/61 , H04N21/236
CPC分类号: H04N21/2353 , H04N5/44591 , H04N21/21805 , H04N21/23614 , H04N21/2362 , H04N21/2365 , H04N21/2368 , H04N21/4316 , H04N21/4345 , H04N21/4348 , H04N21/4858 , H04N21/6112 , H04N21/64322
摘要: There is provided a data stream comprising a plurality of program streams and at least one multistream descriptor. The multistream descriptor defines a multistream group identifier; and the identity of the program streams that are members of the multistream group.
摘要翻译: 提供了包括多个节目流和至少一个多数据流描述符的数据流。 多数据流描述符定义了一个多数据流组标识符; 以及作为多流组的成员的程序流的身份。
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公开(公告)号:US20150012929A1
公开(公告)日:2015-01-08
申请号:US14380328
申请日:2012-02-23
申请人: Michael Huber
发明人: Michael Huber
IPC分类号: H04L29/08 , H04N21/643 , H04N21/2662 , H04N21/61 , H04L29/06 , H04N21/24
CPC分类号: H04L67/22 , H04L65/4084 , H04L65/80 , H04N21/2402 , H04N21/2662 , H04N21/6125 , H04N21/64322
摘要: There is provided a node in a content distribution network, the node arranged to distribute content to a plurality of clients. The node comprises a client monitor and a quality module. The client monitor identifies how many clients are streaming the same content. The quality module is arranged to increase the streamed quality of content when a plurality of clients greater than a threshold value stream the same content.
摘要翻译: 在内容分发网络中提供了节点,该节点被布置为将内容分发到多个客户端。 节点包括客户端监视器和质量模块。 客户端监视器识别有多少个客户端正在流传输相同的内容。 当大于阈值的多个客户端流相同的内容时,质量模块被设置为增加流内容质量。
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53.
公开(公告)号:US20140343401A1
公开(公告)日:2014-11-20
申请号:US13893740
申请日:2013-05-14
申请人: Michael Huber , Jonas Honegger , Mu Young Lee
发明人: Michael Huber , Jonas Honegger , Mu Young Lee
CPC分类号: A61B6/032 , A61B5/055 , A61B5/1127 , A61B5/113 , A61B5/7289 , A61B6/5288 , A61B2090/3975 , A61N5/1037 , A61N5/1049 , A61N5/1068 , A61N2005/1051 , A61N2005/1061
摘要: A medical method includes: obtaining marker positions at a plurality of time points; determining a first subset of the marker positions that belongs to a first phase bin; using the marker positions in the first subset to determine a first variance information, wherein the first variance information is determined using a processor; and storing the first variance information in a non-transitory medium.
摘要翻译: 医疗方法包括:在多个时间点获得标记位置; 确定属于第一相位仓的标记位置的第一子集; 使用第一子集中的标记位置来确定第一方差信息,其中使用处理器确定第一方差信息; 以及将所述第一方差信息存储在非暂时介质中。
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公开(公告)号:US20140205612A1
公开(公告)日:2014-07-24
申请号:US13780776
申请日:2013-02-28
申请人: Po-Ying Chan-Hui , Katherine Doores , Michael Huber , Stephen Kaminsky , Steven Frey , Ole Olsen , Jennifer Mitcham , Matthew Moyle , Sanjay K. Phogat , Dennis R. Burton , Laura Marjorie Walker , Pascal Raymond Georges Poignard , Wayne Koff , Melissa Danielle De Jean De St. Marcel Simek-Lemos
发明人: Po-Ying Chan-Hui , Katherine Doores , Michael Huber , Stephen Kaminsky , Steven Frey , Ole Olsen , Jennifer Mitcham , Matthew Moyle , Sanjay K. Phogat , Dennis R. Burton , Laura Marjorie Walker , Pascal Raymond Georges Poignard , Wayne Koff , Melissa Danielle De Jean De St. Marcel Simek-Lemos
CPC分类号: C07K16/1063 , A61K39/21 , A61K2039/505 , C07K16/1045 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies may be characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.
摘要翻译: 本发明提供了一种获得广泛中和抗体(bNab)的方法,包括筛选来自供体PBMC样品的记忆B细胞培养物,以抵抗多种HIV-1物种的中和活性,克隆显示广泛中和活性的记忆B细胞; 并从该记忆B细胞培养物中拯救单克隆抗体。 所得到的单克隆抗体的特征在于它们以天然或单体形式选择性地结合来自Env蛋白的表位的能力,以及抑制HIV-1物种从多个进化枝的感染的能力。 提供了含有用于预防,诊断和治疗HIV感染的人单克隆抗HIV抗体的组合物。 提供了通过使用来自gp120的可变环内的保守区域的表位进行免疫来产生这种抗体的方法。 还提供了产生抗艾滋病毒1型免疫球蛋白的免疫原。 此外,提供了使用合适表位的疫苗接种方法。
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55.
公开(公告)号:US20140201795A1
公开(公告)日:2014-07-17
申请号:US13993687
申请日:2010-12-15
申请人: Michael Huber , Hans Byström , Mats Cedervall , Johan Kwarnmark
发明人: Michael Huber , Hans Byström , Mats Cedervall , Johan Kwarnmark
IPC分类号: H04N21/6375 , H04N21/234 , H04N21/643 , H04N21/44 , H04N21/438 , H04N21/236 , H04N21/434
CPC分类号: H04N21/23418 , H04L65/4076 , H04L65/4084 , H04L65/607 , H04L65/608 , H04L65/80 , H04N21/23605 , H04N21/23617 , H04N21/4343 , H04N21/4349 , H04N21/4384 , H04N21/44004 , H04N21/6375 , H04N21/64322
摘要: A method for re-transmitting missing packets in an improved manner in association with transmitting an MPEG transport stream between a client and a server of a communication network is provided. New type of customized control packets are introduced which are periodically embedded into the transport stream at the server from which the MPEG transport stream is distributed, wherein each of the embedded control packets is provided with package identification data. A client receiving the MPEG transport stream, including the embedded customized control packets, will, on the basis of the package identification data obtained from a customized control packet be able to identify each of n packets which were inserted by the server into the transport stream subsequent to the respective customized control packet.
摘要翻译: 提供了一种与在通信网络的客户端和服务器之间传输MPEG传输流相关联地以改进的方式重新发送丢失分组的方法。 引入了新型的定制控制分组,其周期性地嵌入在分发MPEG传输流的服务器处的传输流中,其中每个嵌入式控制分组被提供有包标识数据。 接收包括嵌入式定制控制分组的MPEG传输流的客户端将根据从定制的控制分组获得的包标识数据能够将服务器插入的n个分组中的每一个标识到传输流中 到相应的定制控制分组。
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公开(公告)号:US08670966B2
公开(公告)日:2014-03-11
申请号:US12534962
申请日:2009-08-04
申请人: Kashif Rashid , Daniel Colin-Nesbitt Lucas-Clements , Aron Edward Hallquist , Michael Huber , Trevor Graham Tonkin , Andrew Michael Shand
发明人: Kashif Rashid , Daniel Colin-Nesbitt Lucas-Clements , Aron Edward Hallquist , Michael Huber , Trevor Graham Tonkin , Andrew Michael Shand
CPC分类号: G06Q10/04 , E21B43/122
摘要: Methods and systems for performing well network production optimizations are described. For example, in one embodiment, a method of allocating an applied resource throughout a well network includes receiving topological data into an analytical model of a well network having one or more wells. The topological data includes a plurality of performance curves that relate well performance to one or more levels of an applied resource. The method also includes determining an optimum allocation of the applied resource using the analytical model to maximize an operating parameter of the well network, including converting a portion the analytical model having one or more wells and a linear inequality relationship to a modified portion having a single variable and a linear equality constraint.
摘要翻译: 描述了用于执行良好网络生产优化的方法和系统。 例如,在一个实施例中,在整个井网络中分配应用资源的方法包括将拓扑数据接收到具有一个或多个井的井网络的分析模型中。 拓扑数据包括将井性能与应用资源的一个或多个级别相关联的多个性能曲线。 该方法还包括使用分析模型来确定应用资源的最佳分配,以最大化井网络的运行参数,包括将具有一个或多个井的分析模型和线性不等式关系的部分转换为具有单个 变量和线性等式约束。
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57.
公开(公告)号:US08408973B2
公开(公告)日:2013-04-02
申请号:US12869412
申请日:2010-08-26
CPC分类号: B24B35/00
摘要: The disclosure relates to a finishing apparatus for finish machining of rotationally symmetric workpiece surfaces having a finish belt guide which has a guiding body for guiding the finish belt, wherein the guiding body comprises a shell-like guiding surface along which the finish belt can be guided or is guided between an insertion end of the finish belt and a withdrawal end of the finish belt, wherein the guiding surface is mounted in a resiliently elastic manner in the radial direction, wherein, when seen in the circumferential direction, the guiding surface extends in a continuous manner between the insertion end of the finish belt and the withdrawal end of the finish belt over at least a part of the width of said guiding surface and is mounted in a resiliently elastic manner.
摘要翻译: 本发明涉及一种用于精加工旋转对称的工件表面的精加工装置,其具有精密带导向件,该精密带导向件具有用于引导精加工带的导向主体,其中,导向体包括壳形导向表面,精加工带沿该引导体可被引导 或者在精加工带的插入端和精加工带的退出端之间被引导,其中,引导表面沿径向方向以弹性弹性方式安装,其中当从圆周方向看时,引导表面在 精加工带的插入端和精加工带的退出端之间的连续方式在所述引导表面的宽度的至少一部分上,并以弹性弹性方式安装。
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公开(公告)号:US08127512B2
公开(公告)日:2012-03-06
申请号:US11100145
申请日:2005-04-06
申请人: John L. Pierson , Michael Huber , Jerome Thomson
发明人: John L. Pierson , Michael Huber , Jerome Thomson
摘要: A roofing system formed of a plurality of support members secured to a load bearing roof deck. A plurality of roofing panels are positioned on the support members and are oriented to form overlapping joints between the panels. Sealant is positioned within the overlapping joints of the panels. A compression bar is positioned over the overlapping joints and is secured to the overlapping joints and support member by a fastener arrangement.
摘要翻译: 一种屋顶系统,其由固定到承重屋顶甲板上的多个支撑构件形成。 多个屋顶板被定位在支撑构件上并且被定向成在板之间形成重叠的接头。 密封剂位于面板的重叠接头内。 压缩杆定位在重叠接头上方,并通过紧固件装置固定到重叠接头和支撑构件。
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公开(公告)号:US20120041773A1
公开(公告)日:2012-02-16
申请号:US12855126
申请日:2010-08-12
申请人: Patrik Kunz , Michael Huber
发明人: Patrik Kunz , Michael Huber
IPC分类号: G06Q50/00
CPC分类号: G06F19/3481 , G06Q50/22 , G16H50/70
摘要: In one embodiment of the invention, a computerized method for producing a treatment decision for adaptive radiation therapy (ART) is disclosed. The method comprises several steps. First, patient specific input data regarding a patient and general patient population data are input into a treatment decision engine. Next, this data is analyzed in order to adjust a set of interrelationships and thresholds to fit the ART regimen for which a decision is being processed. In a third step, the interrelationships and thresholds are applied to the data using a processing module which formulates a decision regarding the current ART regimen, and metadata regarding the medical condition of the patient. Finally, the decision and metadata are outputted such that they are accessible to a user. Using such a method, a treatment decision for ART is produced.
摘要翻译: 在本发明的一个实施例中,公开了一种用于产生用于自适应放射治疗(ART)的治疗决定的计算机化方法。 该方法包括几个步骤。 首先,关于患者和一般患者群体数据的患者特定输入数据被输入到治疗决策引擎中。 接下来,分析这些数据以便调整一组相互关系和阈值以适应正在处理决定的ART方案。 在第三步骤中,使用处理模块将相关关系和阈值应用于数据,所述处理模块制定关于当前ART方案的决定以及关于患者的医疗状况的元数据。 最后,输出决定和元数据,使得它们可被用户访问。 使用这种方法,产生用于ART的治疗决定。
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公开(公告)号:US20100307084A1
公开(公告)日:2010-12-09
申请号:US12783653
申请日:2010-05-20
申请人: Frank Resso , George Jones , Ron Nelson , Michael Huber , John Pierson
发明人: Frank Resso , George Jones , Ron Nelson , Michael Huber , John Pierson
CPC分类号: E04D1/34 , E04D3/366 , F24S10/75 , F24S20/67 , F24S25/615 , F24S25/63 , F24S2025/6004 , Y02B10/20 , Y02E10/44 , Y02E10/47
摘要: An anchoring clip system that includes an anchoring clip that has a top flange portion and a base flange that can be connect to a substructure, and a cap member designed to be inserted over a portion of the roof panels so as to secure the roof panels to the anchoring clip. The anchoring clip system can optionally be designed to allow for fluid flow through or on one or more components of the anchoring clip system. The anchoring clip system can optionally include a locking crown that improves the wind uplift resistance of the panels.
摘要翻译: 一种锚固夹系统,其包括具有顶部凸缘部分和可以连接到下部结构的基部凸缘的锚固夹子,以及盖构件,其被设计成插入在顶板的一部分上以便将屋顶板固定到 固定夹。 锚定夹系统可以可选地设计成允许流体流过锚定夹系统中的一个或多个部件。 锚定夹系统可以可选地包括提高面板的风升起阻力的锁定冠。
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