公开(公告)号：US20140188196A1

公开(公告)日：2014-07-03

申请号：US14191399

申请日：2014-02-26

申请人： Michael Ryan

发明人： Michael Ryan

IPC分类号： A61N5/06 ,  A61D99/00

CPC分类号： A61N5/0622 ,  A01K1/0218 ,  A01K1/035 ,  A01K31/19 ,  A61D99/00 ,  A61N2005/0662

摘要： Methods of weight treatment in animals are presented including: stimulating a retinal ganglia of the animal by an exposure to a narrow spectrum light. In some embodiments, the stimulating the retinal ganglia of the animal is associated with a stimulation of melanopsin. In some embodiments, the stimulation of melanopsin is associated with a inhibition of melatonin secretion. In some embodiments, inhibition of melatonin secretion is associated with a stimulation of leptin secretion. In some embodiments, the stimulation of leptin secretion is associated with a decrease in appetite in the animal. In some embodiments, the exposure to the narrow spectrum light is associated with a weight loss in the animal. In some embodiments, the narrow spectrum light is in a spectrum range of approximately 435 to 520 nanometers.

摘要翻译： 呈现动物体重治疗方法包括：通过暴露于窄光谱光来刺激动物的视网膜神经节。 在一些实施方案中，刺激动物的视网膜神经节与黑色素的刺激有关。 在一些实施方案中，黑色素的刺激与抑制褪黑激素分泌有关。 在一些实施方案中，抑制褪黑激素分泌与瘦蛋白分泌的刺激相关。 在一些实施方案中，瘦素分泌的刺激与动物的食欲降低有关。 在一些实施方案中，暴露于窄光谱光与动物体重减轻有关。 在一些实施例中，窄光谱光在约435至520纳米的光谱范围内。

公开(公告)号：US20130110221A1

公开(公告)日：2013-05-02

申请号：US13661110

申请日：2012-10-26

申请人： Triona Campbell ,  Michael Ryan

发明人： Triona Campbell ,  Michael Ryan

IPC分类号： A61F2/82

CPC分类号： A61F2/04 ,  A61F2/82 ,  A61F2002/044 ,  A61F2002/068

摘要： Stents with inwardly-directed protrusions are described. An exemplary stent has a main body having a longitudinal axis, a first end, a second end, an outer surface, and an inner surface. The main body defines a lumen extending from the first end to the second end. A protrusion is disposed on and extends inward from the inner surface of the main body. The protrusion extends along a path on the inner surface and has a pitch and a depth.

摘要翻译： 描述具有向内突出的支架。 示例性支架具有主体，其具有纵向轴线，第一端部，第二端部，外部表面部和内部表面。 主体限定从第一端延伸到第二端的内腔。 突起设置在主体的内表面上并从主体的内表面向内延伸。 突出部沿着内表面上的路径延伸并具有间距和深度。

公开(公告)号：US20120185031A1

公开(公告)日：2012-07-19

申请号：US13346195

申请日：2012-01-09

申请人： Michael Ryan ,  John Neilan

发明人： Michael Ryan ,  John Neilan

IPC分类号： A61F2/84

CPC分类号： A61F2/966 ,  A61F2002/9517 ,  A61F2002/9665

摘要： A stent delivery system and a method for implanting a stent are provided. The system includes an elongate shaft including a proximal portion, a distal portion, a lumen extending at least partially therethrough, and a stent-receiving portion on the distal shaft portion. The system also includes a stent positioned at the stent-receiving portion of the elongate shaft, the stent having a constrained configuration and an expanded configuration. Proximal and distal constraining members releasably connected to the stent and having a first position and a second position are also included. The proximal and distal constraining members cooperatively apply longitudinal tensile force to at least a portion of the stent with the proximal and distal constraining members each in the first position. A drive system configured to simultaneously move the proximal and distal constraining members is provided, including a threaded drive shaft in mechanical communication with a rotatable handle.

摘要翻译： 提供支架输送系统和植入支架的方法。 所述系统包括细长轴，所述细长轴包括近端部分，远端部分，至少部分延伸穿过其中的内腔和远端轴部分上的支架接收部分。 该系统还包括定位在细长轴的支架接收部分的支架，支架具有约束构造和扩张构型。 还包括可释放地连接到支架并且具有第一位置和第二位置的近端和远端约束构件。 近端和远端约束构件协同地将纵向张力施加到支架的至少一部分，其中近侧和远端约束构件各自处于第一位置。 提供了构造成同时移动近侧和远侧约束构件的驱动系统，包括与可旋转手柄机械连通的螺纹驱动轴。

公开(公告)号：US20120101963A1

公开(公告)日：2012-04-26

申请号：US13344174

申请日：2012-01-05

申请人： Frank LAQUINTA ,  Michael McGinley ,  Michael Ryan

发明人： Frank LAQUINTA ,  Michael McGinley ,  Michael Ryan

IPC分类号： G06Q40/06

CPC分类号： G06Q40/04 ,  G06Q40/00 ,  G06Q40/06

摘要： The present invention relates generally to the field of computer-assisted business methods, and to system and articles-of-manufacture for implementing such methods. More particularly, the invention relates to computer-based methods, apparatus and articles-of-manufacture for supporting the coordination, communication, record-keeping, accounting, security and scheduling needs for the syndicate associated with an initial public offering (“IPO”) or other new financial issue. While the invention is exemplified and discussed herein with reference to IPO's, those skilled in the art will appreciate that the present invention is equally applicable to other types of securities and debt instruments, such as preferred stock, corporate bonds, municipal bonds, etc.

摘要翻译： 本发明一般涉及计算机辅助业务方法领域，以及用于实施这些方法的系统和制造制品。 更具体地说，本发明涉及基于计算机的方法，装置和制造用品，用于支持与首次公开发行（“IPO”）相关联的集团的协调，通信，记录保存，会计，安全和调度需求， 或其他新的财务问题。 虽然本发明在此参考IPO的例子和讨论，但本领域技术人员将理解，本发明同样适用于其他类型的证券和债务工具，例如优先股，公司债券，市政债券等。

公开(公告)号：US20120038967A1

公开(公告)日：2012-02-16

申请号：US13203146

申请日：2010-02-24

申请人： Gavin Copeland ,  Alain Briancon ,  Martin Moeller ,  Nigel Leyland ,  Chris Giacoponello ,  Micheal Cassidy ,  Christian Grave ,  David Corr ,  David Bevk ,  Michael Ryan

发明人： Gavin Copeland ,  Alain Briancon ,  Martin Moeller ,  Nigel Leyland ,  Chris Giacoponello ,  Micheal Cassidy ,  Christian Grave ,  David Corr ,  David Bevk ,  Michael Ryan

IPC分类号： G02F1/155

CPC分类号： G02F1/1523 ,  C09K9/02 ,  C09K2211/1007 ,  C09K2211/1029 ,  G02F1/15 ,  G02F1/1525 ,  G02F1/1533 ,  G02F1/155 ,  G02F1/157 ,  G09G3/38

摘要： The present invention provides for a display device and a method to manufacture the display device. The display device includes: a transparent layer; a coloring electrode; a separator; a second electrode; an electrolyte permeating throughout the display device; and a back layer positioned on the back side of the display. The transparent layer, which has a top surface and a bottom surface, is positioned at the viewer side of the display. The coloring electrode is positioned on the transparent layer bottom surface and includes: a connected conductor system formed from one or more heterogeneous conductive layers and a coloring layer, with the proviso that the heterogeneous conductive layers are not positioned between the transparent layer bottom surface and the coloring layer. The conductor heterogeneity includes variations in one or more of: conductor material composition; conductor layer dimension; conductor layer pattern; conductor layer grid design, and combinations thereof. The separator layer is positioned between the coloring electrode and the second electrode.

摘要翻译： 本发明提供一种显示装置和制造该显示装置的方法。 显示装置包括：透明层; 着色电极; 分隔符 第二电极; 渗透整个显示装置的电解质; 以及位于显示器背面的背层。 具有顶表面和底表面的透明层位于显示器的观察者侧。 着色电极位于透明层底表面上，包括：由一个或多个非均匀导电层和着色层形成的连接导体系，条件是不均匀导电层不位于透明层底表面和 着色层。 导体异质性包括：导体材料组成中的一种或多种的变化; 导体层尺寸; 导体层图案; 导体层网格设计及其组合。 隔离层位于着色电极和第二电极之间。

公开(公告)号：US20110174113A1

公开(公告)日：2011-07-21

申请号：US12688979

申请日：2010-01-18

申请人： Geoffrey Motteram ,  Michael Ryan

发明人： Geoffrey Motteram ,  Michael Ryan

IPC分类号： C22B23/00

CPC分类号： C22B23/043 ,  C22B3/08 ,  C22B3/22 ,  Y02P10/234

摘要： Nickel is recovered from a nickeliferous ore, where the ore includes impurities in the form of metals other than nickel and cobalt. The ore is subjected to atmospheric leaching using sulphuric acid to dissolve nickel and cobalt from the ore and produce a leach liquor. The sulphuric acid is regenerated by rapidly heating the leach liquor to a temperature in excess of 120° C. to produce a slurry including sulphuric acid and precipitated oxides of impurities present in the leach liquor, and separating the precipitated oxides from the slurry to produce a clarified acid rich liquor stream for recycle to leaching.

摘要翻译： 镍从含镍矿石中回收，其中矿石包括镍和钴以外的金属形式的杂质。 使用硫酸对矿石进行大气浸出，从矿石中溶解镍和钴，生成浸出液。 通过将浸出液快速加热到超过120℃的温度来再生硫酸，以产生包含存在于浸出液中的硫酸和沉淀的杂质的杂质的浆料，并将沉淀的氧化物与浆料分离以产生 澄清含酸的液体物流，以循环浸出。

公开(公告)号：US20110170162A1

公开(公告)日：2011-07-14

申请号：US13062630

申请日：2009-09-08

申请人： Alain Briancon ,  Martin Moeller ,  Michael Ryan ,  Nigel Leyland

发明人： Alain Briancon ,  Martin Moeller ,  Michael Ryan ,  Nigel Leyland

IPC分类号： G02F1/153 ,  B05D5/12

CPC分类号： G02F1/153 ,  B82Y20/00 ,  G02F2202/36

摘要： The present disclosure provides for printed display, a method of manufacturing a printed display, and a system incorporating a printed display having a porous substrate The printed display includes a porous substrate structure, a first functional layer, a second functional layer, and an electrolyte layer percolated within the porous substrate structure The porous substrate structure may be disposed between the first functional layer and the second functional layer The display may include a third functional layer disposed over or under the first functional layer Alternatively, the display may include a fourth functional layer disposed over the second functional layer.

摘要翻译： 本公开内容提供印刷显示器，制造印刷显示器的方法以及结合具有多孔基底的印刷显示器的系统。印刷显示器包括多孔基底结构，第一功能层，第二功能层和电解质层 在多孔基材结构内渗透多孔基材结构可以设置在第一功能层和第二功能层之间。显示器可以包括设置在第一功能层上或下的第三功能层。或者，显示器可以包括布置在第一功能层和第二功能层之间的第四功能层 在第二功能层上。

公开(公告)号：US20100220378A1

公开(公告)日：2010-09-02

申请号：US12738039

申请日：2008-10-15

申请人： Martin Moeller ,  Henrik Lindstrom ,  Michael Ryan ,  David Corr ,  Alain Briancon ,  Micheal Cassidy

发明人： Martin Moeller ,  Henrik Lindstrom ,  Michael Ryan ,  David Corr ,  Alain Briancon ,  Micheal Cassidy

IPC分类号： G02F1/153 ,  G02F1/163

CPC分类号： G02F1/163 ,  G02F1/155

摘要： A device is disclosed that combines a battery system with an electrochromic system by judicious selection of electrodes and the connection of the appropriate electrodes to generate internal as well as external current flows. This system allows the elimination of a battery component reducing cost and improving manufacturing yield by reduction of the number of parts and number of interconnections. However, the design can be further extended to the combination of a battery system with a sensing system.

摘要翻译： 公开了一种通过明智地选择电极和连接适当的电极以产生内部和外部电流来将电池系统与电致变色系统组合的装置。 该系统通过减少部件数量和互连数量，可以消除电池组件降低成本并提高制造成品率。 然而，该设计可以进一步扩展到电池系统与感测系统的组合。

公开(公告)号：US20100193147A1

公开(公告)日：2010-08-05

申请号：US12757121

申请日：2010-04-09

申请人： Michael Ryan ,  William Brevard

发明人： Michael Ryan ,  William Brevard

IPC分类号： D21H17/33 ,  C08L33/00 ,  C08L77/00

CPC分类号： D21H21/20 ,  D21H17/37 ,  D21H17/43 ,  D21H17/72 ,  D21H21/18 ,  D21H21/24 ,  D21H23/765

摘要： The invention relates to a composition comprising (a) a functional promoter comprising a water-soluble anionic polymer having a molecular weight of at least about 50,000 daltons and a molecular weight charge index value of at least about 10,000; (b) a cationic surfactant component; such that when the composition treats a fibrous substrate, in conjunction with a cationic strength agent, the treated fibrous substrate exhibits (i) a ratio of wet tensile strength to dry tensile strength ranging from about 1:5 o to about 1:2 and (ii) an increase in a ratio of wet tensile strength to dry tensile strength of at least about 10%, as compared to when the fibrous substrate is treated with the functional promoter and without a surfactant. The invention also relates to a paper product made with such a system, and method for imparting wet strength to a paper product with the functional promoter.

摘要翻译： 本发明涉及一种组合物，其包含（a）功能性促进剂，其包含分子量至少为约50,000道尔顿且分子量电荷指数值为至少约10,000的水溶性阴离子聚合物; （b）阳离子表面活性剂组分; 使得当组合物处理纤维底物时，与阳离子强度剂结合，经处理的纤维基质表现出（i）湿拉伸强度与干拉伸强度的比例为约1:5至约1:2和（ ii）与用功能促进剂处理和不用表面活性剂处理纤维底物时相比，湿拉伸强度与干拉伸强度的比例增加至少约10％。 本发明还涉及一种用这种系统制成的纸制品，以及赋予纸制品功能促进剂湿强度的方法。

公开(公告)号：US20100168834A1

公开(公告)日：2010-07-01

申请号：US12649046

申请日：2009-12-29

申请人： Michael Ryan ,  Donagh O'Sullivan ,  Fionan Keady

发明人： Michael Ryan ,  Donagh O'Sullivan ,  Fionan Keady

IPC分类号： A61F2/82

CPC分类号： A61F2/95 ,  A61F2/966 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2002/9534

摘要： A delivery device for deploying an expandable prosthesis and method of use thereof are described. The delivery device includes an outer sheath that is capable of retracting in a proximal direction and resheathing over the prosthesis in a distal direction. The device includes a drive pulley that can engage gears to retract or resheath the outer catheter in relation to the prosthesis. In some embodiments, the delivery device may include a reinforced outer sheath disposed over an inner elongate member, the reinforced outer sheath comprising a proximal section reinforced with a braid, a distal section reinforced with a coil and an overlapping section extending between the proximal section and the distal section. Additionally or alternatively, the delivery device may include a stabilizing element for releasably holding the stent to the inner catheter.

摘要翻译： 描述了用于展开可扩张假体的输送装置及其使用方法。 输送装置包括能够沿近端方向回缩并在远端方向上再次穿过假体的外护套。 该装置包括驱动滑轮，该驱动滑轮可啮合齿轮以使外导管相对于假体缩回或再鞘合。 在一些实施例中，递送装置可以包括设置在内部细长构件上的增强外护套，所述加强外护套包括用编织物增强的近端部分，用线圈加强的远侧部分和在近端部分和 远端部分。 附加地或替代地，输送装置可以包括用于将支架可释放地保持在内导管上的稳定元件。