公开(公告)号：US07186362B2

公开(公告)日：2007-03-06

申请号：US11067139

申请日：2005-02-25

申请人： Aiguo Wang ,  Aaron Essner

发明人： Aiguo Wang ,  Aaron Essner

IPC分类号： A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/44

CPC分类号： A61L27/16 ,  A61L27/26 ,  C08L23/00

摘要： A prosthetic medical device exhibiting improved wear resistance is fabricated by sealing at least one polyolefinic material in an airtight container and providing an inert atmosphere within the airtight container. The polyolefinic material is exposed to an irradiation source to yield a cross-linked irradiated polyolefinic material. At least one non-irradiated polyolefinic material is blended with the irradiated polyolefinic material, and the prosthetic medical device is formed from the blended material. Selectively cross-linked polymeric compositions may be created by blending a specific amount of cross-linked resins with a specific amount of uncross-linked resins then cured into a polymeric matrix whereby the desired degree or percentage of overall cross-linking is obtained. The polymeric material may then be formed directly into a finished article by injection molding the polymeric material.

摘要翻译： 通过在气密容器中密封至少一种聚烯烃材料并在气密容器内提供惰性气氛来制造显示出改进的耐磨性的假体医疗装置。 将聚烯烃材料暴露于照射源以产生交联的辐照聚烯烃材料。 将至少一种未经照射的聚烯烃材料与被照射的聚烯烃材料混合，并且所述假体医疗装置由所述混合材料形成。 选择性交联的聚合物组合物可以通过将特定量的交联树脂与特定量的未交联树脂混合，然后固化成聚合物基体，从而获得所需的整体交联度或百分比来产生。 然后可以通过注射模制聚合物材料将聚合物材料直接形成成品。

公开(公告)号：US06849224B2

公开(公告)日：2005-02-01

申请号：US10094789

申请日：2002-03-11

申请人： Aiguo Wang ,  Aaron Paul Essner ,  Alfred J. Zarnowski

发明人： Aiguo Wang ,  Aaron Paul Essner ,  Alfred J. Zarnowski

IPC分类号： A61L27/00 ,  A61F2/00 ,  A61F2/30 ,  A61L27/16 ,  B29C35/02 ,  B29C35/08 ,  B29C67/00 ,  B29K23/00 ,  B29L31/48 ,  C08J7/00 ,  C08L23/06 ,  B29C71/04

CPC分类号： B29C35/08 ,  A61F2/30 ,  A61F2/3094 ,  A61F2002/30004 ,  A61F2250/0014 ,  A61L27/16 ,  B29C35/0266 ,  B29C2035/0844 ,  B29C2035/085 ,  B29C2035/0877 ,  B29K2023/065 ,  B29K2023/0675 ,  B29K2023/0683 ,  B29K2105/0088 ,  B29K2995/0087 ,  B29L2031/7532 ,  C08L23/06

摘要： An improved prosthetic medical device having improved wear resistance and toughness is provided in the present application. A method is provided to selectively cross-link the polymeric matrix comprising the medical device by employing an interrupting means such as a mask, wire mesh or chopper wheel placed in between the medical device and irradiation source. In addition, the medical device may be translated while being irradiated to further effect the selective cross-linking. The present invention also provides for an injection molding process wherein a prosthetic medical device is formed in a single step, then selectively cross-linked.

摘要翻译： 在本申请中提供了具有改善的耐磨性和韧性的改进的假体医疗装置。 提供了一种方法，通过采用放置在医疗装置和照射源之间的掩模，丝网或切碎轮等中断装置来选择性地交联包含医疗装置的聚合物基质。 此外，可以在照射医疗装置的同时进行平移以进一步影响选择性交联。 本发明还提供了一种注射成型方法，其中在单一步骤中形成假体医疗装置，然后选择性地交联。

公开(公告)号：US06818171B2

公开(公告)日：2004-11-16

申请号：US10095240

申请日：2002-03-11

申请人： Aiguo Wang ,  Aaron Paul Essner ,  Alfred J. Zarnowski

发明人： Aiguo Wang ,  Aaron Paul Essner ,  Alfred J. Zarnowski

IPC分类号： H05B600

CPC分类号： B29C35/08 ,  A61F2/30 ,  A61F2/3094 ,  A61F2002/30004 ,  A61F2250/0014 ,  A61L27/16 ,  B29C35/0266 ,  B29C2035/0844 ,  B29C2035/085 ,  B29C2035/0877 ,  B29K2023/065 ,  B29K2023/0675 ,  B29K2023/0683 ,  B29K2105/0088 ,  B29K2995/0087 ,  B29L2031/7532 ,  C08L23/06

摘要： An improved prosthetic medical device having improved wear resistance and toughness is provided in the present application. A method is provided to selectively cross-link the polymeric matrix comprising the medical device by employing an interrupting means such as a mask, wire mesh or chopper wheel placed in between the medical device and irradiation source. In addition, the medical device may be translated while being irradiated to further effect the selective cross-linking. The present invention also provides for an injection molding process wherein a prosthetic medical device is formed in a single step, then selectively cross-linked.

摘要翻译： 在本申请中提供了具有改善的耐磨性和韧性的改进的假体医疗装置。 提供了一种方法，通过采用放置在医疗装置和照射源之间的掩模，丝网或切碎轮等中断装置来选择性地交联包含医疗装置的聚合物基质。 此外，可以在照射医疗装置的同时进行平移，以进一步影响选择性交联。 本发明还提供了一种注射成型方法，其中在单一步骤中形成假体医疗装置，然后选择性地交联。