公开(公告)号：US08870767B2

公开(公告)日：2014-10-28

申请号：US12988422

申请日：2009-04-02

Applicant: Clemens Bulitta ,  Stefan Förtsch ,  Norbert Gläsel ,  Rainer Kuth ,  Bernhard Roas ,  Sebastian Schmidt ,  Rainer Graumann ,  Arne Hengerer ,  Ludwig Herbst

Inventor： Clemens Bulitta ,  Stefan Förtsch ,  Norbert Gläsel ,  Rainer Kuth ,  Bernhard Roas ,  Sebastian Schmidt ,  Rainer Graumann ,  Arne Hengerer ,  Ludwig Herbst

IPC: A61B5/07 ,  A61B5/145 ,  A61B5/00 ,  A61B1/00 ,  A61B1/04 ,  A61B1/05 ,  A61B5/1459

CPC classification number: A61B5/073 ,  A61B1/00016 ,  A61B1/00158 ,  A61B1/041 ,  A61B1/05 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/42 ,  A61B5/6861

Abstract: An endocapsule has a measurement chamber therein containing a sensor that detects at least one metabolic product of a specific bacterium in a hollow organ of a human or animal gastrointestinal tract. The endocapsule is introduced into the hollow organ wherein detection of the at least one metabolic product takes place.

Abstract translation: 内囊具有其中包含测量室的测量室，所述传感器检测人或动物胃肠道的中空器官中特定细菌的至少一种代谢产物。 将内囊引入中空器官中，其中发生至少一种代谢产物的检测。

公开(公告)号：US08837673B2

公开(公告)日：2014-09-16

申请号：US13419665

申请日：2012-03-14

Applicant: Rainer Graumann

Inventor： Rainer Graumann

IPC: G01N23/04 ,  A61B6/00

CPC classification number: A61B6/5235 ,  A61B6/4441 ,  A61B6/505 ,  A61B6/547

Abstract: In a method for correctly geometrically assigning x-ray images of a patient an optically operating recording device is attached to an x-ray device generating the x-ray images. A dimensionally stable marker surface which can be optically detected by the recording device and defines a reference system is fixed to the patient in a fixed relative position. The x-ray device is brought into a first and second recording position such that the recording device is directed toward the marker surface. In a recording position the x-ray device produces a first and second x-ray image of the patient and the recording device produces a first and second recording of the marker surface. The respective geometric position of the first and second x-ray image is determined in the reference system from the recordings. The first and second x-ray images are correctly geometrically assigned to one another in accordance with their position.

Abstract translation: 在用于正确地几何分配患者的x射线图像的方法中，将光学操作的记录装置附接到产生x射线图像的X射线装置。 可以由记录装置光学检测并限定参考系统的尺寸稳定的标记表面以固定的相对位置固定到患者身上。 X射线装置被带入第一和第二记录位置，使得记录装置指向标记表面。 在记录位置，x射线装置产生患者的第一和第二X射线图像，并且记录装置产生标记表面的第一和第二记录。 在参考系统中从记录中确定第一和第二X射线图像的相应几何位置。 第一和第二X射线图像根据它们的位置被正确地几何地分配给彼此。

公开(公告)号：US08699670B2

公开(公告)日：2014-04-15

申请号：US13451983

申请日：2012-04-20

Applicant: Rainer Graumann ,  Gerhard Kleinszig

Inventor： Rainer Graumann ,  Gerhard Kleinszig

IPC: H05G1/28

CPC classification number: A61B6/584 ,  A61B6/032 ,  A61B6/0492 ,  A61B6/4441 ,  A61B90/39 ,  A61B2090/364 ,  A61B2090/3966

Abstract: In a method for geometrically correct association of at least two 3D image data of a patient, a marker field that defines a reference and is dimensionally stable and can be imaged in an x-ray image, is fixed in a stationary position relative to the patient. An x-ray apparatus is brought into first and second 3D acquisition positions. In each of the 3D acquisition positions, the x-ray apparatus acquires first 2D x-ray images for the associated 3D image data in various positions. The first and second 3D acquisition positions are selected such that a second 2D x-ray image that includes an image of at least a portion of the marker field is acquired in at least one respective position. The respective attitudes of the 3D acquisition position and the 3D image data in the reference system are determined from the image of the marker field in the second 2D x-ray image. First and second image data are geometrically correctly associated with one another according to their respective attitude.

Abstract translation: 在用于对患者的至少两个3D图像数据进行几何正确关联的方法中，限定参考并且尺寸稳定并且可以被成像在X射线图像中的标记场固定在相对于患者的静止位置 。 X射线设备被带入第一和第二3D采集位置。 在每个3D获取位置中，x射线装置获取用于各种位置的相关3D图像数据的第一2D X射线图像。 选择第一和第二3D采集位置使得在至少一个相应位置中获取包括标记场的至少一部分的图像的第二2D X射线图像。 根据第二2D X射线图像中的标记场的图像确定参考系中的3D获取位置和3D图像数据的各自姿态。 第一和第二图像数据根据它们各自的姿态在几何上正确地相关联。

公开(公告)号：US08693622B2

公开(公告)日：2014-04-08

申请号：US13442086

申请日：2012-04-09

Applicant: Rainer Graumann ,  Anna Jerebko

Inventor： Rainer Graumann ,  Anna Jerebko

IPC: A61B6/03 ,  G01N23/04

CPC classification number: A61B6/5241 ,  A61B6/025 ,  A61B6/4441 ,  A61B6/5205

Abstract: Three-dimensional image information is generated of a body part that is larger than the visual field of an X-ray machine. An X-ray source and an X-ray detector are disposed at a first position such that the X-ray source and the X-ray detector can record a first projection image of at least a first section of a body part. Then the first projection image is recorded. The X-ray source and the X-ray detector are next disposed at a second position such that the X-ray source and the X-ray detector can record a second projection image of at least a second section of the body part. The second section partially overlaps the first section. The first and second projection images are merged to form a projected image. A three-dimensional volume of the body part is reconstructed from the plurality of projection images.

Abstract translation: 生成比X射线机的视场大的身体部位的三维图像信息。 X射线源和X射线检测器设置在第一位置，使得X射线源和X射线检测器可以记录身体部分的至少第一部分的第一投影图像。 然后记录第一投影图像。 接下来，X射线源和X射线检测器设置在第二位置，使得X射线源和X射线检测器可以记录身体部分的至少第二部分的第二投影图像。 第二部分与第一部分重叠。 第一和第二投影图像被合并以形成投影图像。 从多个投影图像重建身体部位的三维体积。

公开(公告)号：US20140003700A1

公开(公告)日：2014-01-02

申请号：US14017344

申请日：2013-09-04

Applicant: Gerardo Hermosillo Valadez ,  Xiang Sean Zhou ,  Gerhard Kleinszig ,  Rainer Graumann

Inventor： Gerardo Hermosillo Valadez ,  Xiang Sean Zhou ,  Gerhard Kleinszig ,  Rainer Graumann

IPC: G06T11/00

CPC classification number: G06T11/003 ,  G06T7/0014 ,  G06T2207/30008

Abstract: Disclosed herein is a framework for facilitating fused-image visualization for surgery evaluation. In accordance with one aspect of the framework, at least one pre-operative image and at least one intra-operative image of an anatomical structure are received. A region of interest may be identified in the intra-operative image. The pre-operative image may be straightened, and a symmetric region may be identified in the straightened pre-operative image. The symmetric region is substantially symmetrical to a target region in the straightened pre-operative region. The target region corresponds to the region of interest in the intra-operative image. The symmetric region may be extracted and reflected to generate a reference image. The intra-operative image may be rigidly registered with the reference image to generate registered intra-operative image, which is overlaid on the target region in the straightened pre-operative image to generate a fused image.

Abstract translation: 本文公开了用于促进用于手术评估的融合图像可视化的框架。 根据框架的一个方面，接收解剖结构的至少一个术前图像和至少一个手术内图像。 可以在手术中的图像中识别感兴趣的区域。 可以矫正术前图像，并且可以在矫正的手术前图像中识别对称区域。 对称区域基本对称于矫正术前区域中的目标区域。 目标区域对应于手术中图像中的感兴趣区域。 对称区域可以被提取和反射以产生参考图像。 可以将手术内图像与参考图像刚性地注册，以产生注册的手术中图像，其被覆盖在矫正的术前图像中的目标区域上以产生融合图像。

公开(公告)号：US20130177230A1

公开(公告)日：2013-07-11

申请号：US13735112

申请日：2013-01-07

Applicant: Shaolei Feng ,  Shaohua Kevin Zhou ,  Gerhard Kleinszig ,  Rainer Graumann

Inventor： Shaolei Feng ,  Shaohua Kevin Zhou ,  Gerhard Kleinszig ,  Rainer Graumann

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G06T7/75 ,  G06T2207/10116 ,  G06T2207/30052

Abstract: The pose of an implant represented in a medical image is determined from the medical image. The x-ray image of the implant is compared to a database of the implant viewed at different poses (e.g., viewed from different directions). The implant pose associated with the best match indicates the pose of the implant in the x-ray image.

Abstract translation: 根据医学图像确定在医学图像中表示的植入物的姿势。 将植入物的x射线图像与在不同姿势（例如从不同方向观察）观察的植入物的数据库进行比较。 与最佳匹配关联的植入姿势表示植入物在X射线图像中的姿态。

公开(公告)号：US08199876B2

公开(公告)日：2012-06-12

申请号：US12159490

申请日：2006-11-17

Applicant: Rainer Graumann ,  Nassir Navab

Inventor： Rainer Graumann ,  Nassir Navab

IPC: G01N23/04 ,  G06T7/00

CPC classification number: A61B6/02 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/5235

Abstract: In an imaging system and method for preparing x-ray images and optical images, at least two x-ray images of an examination subject are acquired by emitting x-rays from at least two different x-ray image acquisition points in space. At least two optical exposures are acquired from the examination subject at respective optical exposure origination points that respectively optically correspond to the x-ray image acquisition points. The optical exposures and the x-ray images are superimposed so that each optical image is superimposed with the x-ray image that originated from an x-ray image origination point corresponding to the optical exposure origination point of that optical exposure.

Abstract translation: 在用于制备x射线图像和光学图像的成像系统和方法中，通过从空间中的至少两个不同x射线图像采集点发射X射线来获取检查对象的至少两个X射线图像。 在相应的光学对应于x射线图像采集点的相应的光学曝光起始点处，从检查对象获取至少两个光学曝光。 叠加光学曝光和X射线图像，使得每个光学图像与来自与该光学曝光的光学曝光起始点相对应的x射线图像发起点的X射线图像叠加。

公开(公告)号：US20110015519A1

公开(公告)日：2011-01-20

申请号：US12920781

申请日：2009-03-02

Applicant: Rainer Graumann

Inventor： Rainer Graumann

IPC: A61B6/00

CPC classification number: A61B6/583 ,  A61B6/4405 ,  A61B34/20 ,  A61B2017/00707 ,  A61B2017/00725 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/364 ,  A61B2090/376

Abstract: In a method and medical system for positionally correct association of an image data set of a patient, obtained with the medical system, and an N-coordinate system of an electromagnetic navigation system, before a medical procedure at least one sensor coil is attached to the imaging system, and a transformation matrix between the image data set and the sensor coil is determined. During the medical procedure, the image data set is acquired, and the current position of the sensor coil is determined. The image data set is associated in a positionally correct manner with the N-coordinate system based on the known position of the sensor coil relative to the imaging system, and the transformation matrix.

Abstract translation: 在用于将医疗系统获得的患者的图像数据组与电磁导航系统的N坐标系统的位置正确关联的方法和医疗系统中，在医疗程序之前，至少一个传感器线圈附接到 成像系统和图像数据组与传感器线圈之间的变换矩阵。 在医疗过程中，获取图像数据集，并且确定传感器线圈的当前位置。 基于传感器线圈相对于成像系统的已知位置和变换矩阵，图像数据集以位置正确的方式与N坐标系相关联。

公开(公告)号：US20090141958A1

公开(公告)日：2009-06-04

申请号：US12159490

申请日：2006-11-17

Applicant: Rainer Graumann ,  Nassir Navab

Inventor： Rainer Graumann ,  Nassir Navab

IPC: G06T7/00

CPC classification number: A61B6/02 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/5235

Abstract: In an imaging system and method for preparing x-ray images and optical images, at least two x-ray images of an examination subject are acquired by emitting x-rays from at least two different x-ray image acquisition points in space. At least two optical exposures are acquired from the examination subject at respective optical exposure origination points that respectively optically correspond to the x-ray image acquisition points. The optical exposures and the x-ray images are superimposed so that each optical image is superimposed with the x-ray image that originated from an x-ray image origination point corresponding to the optical exposure origination point of that optical exposure.

Abstract translation: 在用于制备x射线图像和光学图像的成像系统和方法中，通过从空间中的至少两个不同x射线图像采集点发射X射线来获取检查对象的至少两个X射线图像。 在相应的光学对应于x射线图像采集点的相应的光学曝光起始点处，从检查对象获取至少两个光学曝光。 叠加光学曝光和X射线图像，使得每个光学图像与来自与该光学曝光的光学曝光起始点相对应的x射线图像发起点的X射线图像叠加。

公开(公告)号：US20090028291A1

公开(公告)日：2009-01-29

申请号：US12178017

申请日：2008-07-23

Applicant: Rainer Graumann

Inventor： Rainer Graumann

IPC: A61B6/00

CPC classification number: A61B6/00 ,  A61B6/5235 ,  A61B90/36 ,  A61B90/39 ,  A61B2090/364 ,  A61B2090/376 ,  G06T3/4038

Abstract: In an x-ray system and a method for image composition, congruent optical images and x-ray images of subjects provided with markers are generated. A transformation matrix/imaging matrix is formed and applied to the congruent x-ray images based on the detected identical markers in optical images. The transformation matrix is used to compose an aggregate image from the x-ray images.

Abstract translation: 在x射线系统和图像组合方法中，生成具有标记的受试者的全等的光学图像和X射线图像。 基于在光学图像中检测到的相同标记，形成转换矩阵/成像矩阵并将其应用于全等x射线图像。 变换矩阵用于从x射线图像中构成聚合图像。