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    Single pass lead having retractable, actively attached electrode for pacing and sensing
    51.
    发明授权
    Single pass lead having retractable, actively attached electrode for pacing and sensing 失效
    单通引线具有可伸缩的，主动连接的用于起搏和感测的电极

    公开(公告)号：US06345204B1

    公开(公告)日：2002-02-05

    申请号：US09661531

    申请日：2000-09-14

    申请人： Avram Scheiner ,  Ronald W. Heil, Jr. ,  Qingsheng Zhu ,  Peter T. Kelley ,  David M. Flynn ,  John E. Heil

    发明人： Avram Scheiner ,  Ronald W. Heil, Jr. ,  Qingsheng Zhu ,  Peter T. Kelley ,  David M. Flynn ,  John E. Heil

    IPC分类号： A61N105

    CPC分类号： A61N1/0573

    摘要： A single-pass endocardial lead electrode adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity including a lead body with a circumferential outer surface. The lead includes a first distal end electrode which has a first electrical conducting surface which is for positioning within the ventricle of the heart. The lead body also has a second electrode which has a second electrical conducting surface adapted for positioning within the atrium of the heart. Both of the first and the second electrodes are adapted for positioning and fixation to the wall. An active fixation element is used as part of the second electrode. The lead body also includes a curved portion which facilitates the positioning and fixing of the second electrode. In another embodiment, the main lead body includes a recess into which an atrial lead body and the active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element which can also be moved by turning the terminal pin.

    摘要翻译： 一种单程心内膜引导电极，其适于植入在心脏上或其周围并用于连接到用于监测或刺激心脏活动的系统，包括具有周向外表面的引线体。 引线包括第一远端电极，其具有用于定位在心脏心室内的第一导电表面。 引线体还具有第二电极，该第二电极具有适于定位在心脏心房内的第二导电表面。 第一和第二电极都适于定位和固定在墙上。 活性固定元件用作第二电极的一部分。 引线体还包括有助于第二电极的定位和固定的弯曲部分。在另一实施例中，主引线体包括凹部，其中一个端部的心房引线体和主动固定元件可以从凹部 位置到固定在心脏壁上的位置。 主动固定元件也可以通过转动端子销来移动。

    Endocardial lead having defibrillation and sensing electrodes with septal anchoring
    52.
    发明授权
    Endocardial lead having defibrillation and sensing electrodes with septal anchoring 失效
    具有除颤和感应/起搏电极的心内膜导联

    公开(公告)号：US06256541B1

    公开(公告)日：2001-07-03

    申请号：US09062268

    申请日：1998-04-17

    申请人： John E. Heil ,  Ronald W. Heil, Jr. ,  Avram Scheiner ,  Yayun Lin ,  Lyle A. Bye ,  J. John Lattuca

    发明人： John E. Heil ,  Ronald W. Heil, Jr. ,  Avram Scheiner ,  Yayun Lin ,  Lyle A. Bye ,  J. John Lattuca

    IPC分类号： A61N105

    CPC分类号： A61N1/0563 ,  A61N1/0573

    摘要： An endocardial lead comprising an elongate body having a first defibrillation coil electrode, a second defibrillation coil electrode and a first pacing/sensing electrode. The first defibrillation coil electrode has a first end and a second end, where the first end is at or near the distal end of the elongate body and the second end spaced longitudinally from the distal end. The first pacing/sensing electrode is spaced longitudinally along the peripheral surface from the second end of the first defibrillation coil electrode. The second defibrillation coil electrode is spaced longitudinally along the peripheral surface from the first pacing/sensing electrode to afford positioning the first defibrillation coil longitudinally adjacent an apical location of the right ventricle of a heart with the first pacing/sensing electrode within the right ventricle of the heart and the second defibrillation coil within the right atrial chamber or a major vein leading to the right atrial chamber of the heart. The elongate body further includes a curved portion on which the first pacing/sensing electrode is positioned such that the first pacing/sensing electrode extends beyond the peripheral surface of the elongate body to engage the tissue of the heart. The first pacing/sensing electrode further includes a retaining element, where the retaining element is adapted to be embedded in the right ventricle of the heart to secure the first pacing/sensing electrode and the elongate body of the endocardial lead to the right ventricle of the heart.

    摘要翻译： 一种心内膜，其包括具有第一除颤线圈电极，第二除颤线圈电极和第一起搏感测电极的细长体。 第一除颤线圈电极具有第一端和第二端，其中第一端处于细长体的远端处或其附近，并且第二端与远端纵向间隔开。 第一起搏感测电极沿着与第一除颤线圈电极的第二端的外周表面纵向间隔开。 第二除颤线圈电极沿着与第一起搏/感测电极的外周表面纵向间隔开，以使第一除颤线圈与心脏右心室的顶端位置纵向相邻，其中第一起搏/感测电极位于右心室内 右心房中的心脏和第二除颤线圈或通向心脏右心房的主要静脉。 细长主体还包括弯曲部分，第一起搏/感测电极定位在弯曲部分上，使得第一起搏/感测电极延伸超出细长体的周边表面以接合心脏的组织。 第一起搏/感测电极还包括保持元件，其中保持元件适于嵌入心脏的右心室，以将第一起搏/感测电极和心内膜引导件的细长体固定到右心室 心。

    Single pass lead having retractable, actively attached electrode for pacing and sensing
    53.
    发明授权
    Single pass lead having retractable, actively attached electrode for pacing and sensing 失效
    单通引线具有可伸缩的，主动连接的用于起搏和感测的电极

    公开(公告)号：US6152954A

    公开(公告)日：2000-11-28

    申请号：US121006

    申请日：1998-07-22

    申请人： Avram Scheiner ,  Ronald W. Heil, Jr. ,  Qingsheng Zhu ,  Peter T. Kelley ,  David M. Flynn ,  John E. Heil

    发明人： Avram Scheiner ,  Ronald W. Heil, Jr. ,  Qingsheng Zhu ,  Peter T. Kelley ,  David M. Flynn ,  John E. Heil

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0573

    摘要： A single-pass endocardial lead electrode adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity including a lead body with a circumferential outer surface. The lead includes a first distal end electrode which has a first electrical conducting surface which is for positioning within the ventricle of the heart. The lead body also has a second electrode which has a second electrical conducting surface adapted for positioning within the atrium of the heart. Both of the first and the second electrodes are adapted for positioning and fixation to the wall. An active fixation element is used as part of the second electrode. The lead body also includes a curved portion which facilitates the positioning and fixing of the second electrode. In another embodiment, the main lead body includes a recess into which an atrial lead body and the active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element which can also be moved by turning the terminal pin.

    摘要翻译： 一种单程心内膜引导电极，其适于植入在心脏上或其周围并用于连接到用于监测或刺激心脏活动的系统，包括具有周向外表面的引线体。 引线包括第一远端电极，其具有用于定位在心脏心室内的第一导电表面。 引线体还具有第二电极，该第二电极具有适于定位在心脏心房内的第二导电表面。 第一和第二电极都适于定位和固定在墙上。 活性固定元件用作第二电极的一部分。 引线体还包括有助于第二电极的定位和固定的弯曲部分。 在另一个实施例中，主引线主体包括凹部，其中安装在一端的心房引线主体和主动固定元件可以从凹陷位置行进到用于固定到心脏壁的位置。 主动固定元件也可以通过转动端子销来移动。

    Coronary sinus lead having expandable matrix anchor
    54.
    发明授权
    Coronary sinus lead having expandable matrix anchor 失效
    冠状窦导线具有可扩张的基质锚

    公开(公告)号：US5951597A

    公开(公告)日：1999-09-14

    申请号：US59786

    申请日：1998-04-14

    申请人： Randy W. Westlund ,  Bruce A. Tockman ,  Ronald W. Heil, Jr.

    发明人： Randy W. Westlund ,  Bruce A. Tockman ,  Ronald W. Heil, Jr.

    IPC分类号： A61N1/05

    CPC分类号： A61N1/057 ,  A61N2001/0585

    摘要： An intravenous lead for use with a cardiac device for implantation in the coronary venous system of the heart includes a lead body that is adapted to be routed through the vascular system into the coronary sinus with the distal end portion of the lead placed in the great cardiac vein or branch vein. The lead body includes a fixation member disposed just proximal of its tip. The fixation member comprises a radially expandable polymeric matrix that incorporates an osmotic agent so that when placed in a aqueous medium it will swell. Thus, when placed in a cardiac vein, the swelling of the fixation member will anchor the lead against longitudinal displacement due to body motion, blood flow and the beating action of the heart.

    摘要翻译： 用于心脏装置用于植入心脏冠状静脉系统的静脉导管包括引线体，其适于通过血管系统引导到冠状窦中，将引线的远端部分放置在大心脏中 静脉或分支静脉。 引线体包括设置在其尖端附近的固定部件。 固定构件包括可渗透的聚合物基质，其包含渗透剂，使得当放置在水性介质中时，其将溶胀。 因此，当放置在心静脉中时，固定构件的肿胀将由于身体运动，血液流动和心脏的打动作用而使引线抵抗纵向移位。

    Positive fixation device
    55.
    发明授权
    Positive fixation device 失效
    正固定装置

    公开(公告)号：US5314462A

    公开(公告)日：1994-05-24

    申请号：US888492

    申请日：1992-05-27

    申请人： Ronald W. Heil, Jr. ,  Wickham, Jr. Robert W. ,  Bruce H. Kenknight

    发明人： Ronald W. Heil, Jr. ,  Wickham, Jr. Robert W. ,  Bruce H. Kenknight

    IPC分类号： A61N1/05 ,  A61N1/39 ,  A61N1/00

    CPC分类号： A61N1/0573

    摘要： An implantable defibrillation electrode including a conductive distal end portion and a non-conductive proximal end portion is provided with at least a major portion of the length of the distal end portion having a preconfigured shape and being resiliently deformable into a generally straight condition. The distal end portion includes distal and proximal ends and at least one of those ends is hollow and has hook structure shiftably supported therein for movement longitudinally thereof from a retracted position at least substantially contained within the hollow end and an extended position at least substantially fully outwardly projected from the hollow end. Spring structure is provided for yieldingly biasing the hook structure from the extended position toward the retracted position and axial thrust developing structure is slidingly telescoped through the proximal end portion and operatively associated with the hook structure for exerting an axial thrust thereon from the terminal end of the proximal end portion in order to effect shifting of the hook structure from the retracted position to the extended position.

    摘要翻译： 包括导电远端部分和非导电近端部分的可植入除颤电极设置有远端部分的长度的至少大部分具有预先配置的形状并且可弹性变形为大致直线的状态。 远端部分包括远端和近端，并且这些端部中的至少一个端部是中空的并且具有可移动地支撑在其中的钩结构，用于使其纵向移动，从至少基本上容纳在中空端部内的缩回位置和至少基本上完全向外的延伸位置 从中空端突出。 提供弹簧结构用于使挂钩结构从延伸位置朝向缩回位置有效地偏置，并且轴向推力显影结构通过近端部分滑动伸缩并与钩结构可操作地相关联，从而从其上端施加轴向推力 近端部分，以便实现钩结构从缩回位置到延伸位置的移动。

    Implantable medical device and methods for automated detection of infection
    56.
    发明授权
    Implantable medical device and methods for automated detection of infection 有权
    植入式医疗设备和自动检测感染的方法

    公开(公告)号：US08583224B2

    公开(公告)日：2013-11-12

    申请号：US11833548

    申请日：2007-08-03

    申请人： Kent Lee ,  Jonathan T. Kwok ,  Hugo Andres Belalcazar ,  Jennifer Lynn Pavlovic ,  Ronald W. Heil, Jr.

    发明人： Kent Lee ,  Jonathan T. Kwok ,  Hugo Andres Belalcazar ,  Jennifer Lynn Pavlovic ,  Ronald W. Heil, Jr.

    IPC分类号： A61B5/05

    CPC分类号： A61B5/053 ,  A61B5/02405 ,  A61B5/036 ,  A61B5/0816 ,  A61B5/145 ,  A61B5/14539 ,  A61B5/412 ,  A61N1/36521

    摘要： The invention relates to systems, devices, and methods for detecting infections associated with implantable medical devices. In an embodiment, the invention includes a method of detecting infection in a patient including measuring a physiological parameter using a chronically implanted sensor at a plurality of time points and evaluating the physiological parameter measurements to determine if infection is indicated. In an embodiment, the invention includes an implantable medical device including a first chronically implantable sensor configured to generate a first signal corresponding to a physiological parameter and a controller disposed within a housing, the controller configured to evaluate the first physiological parameter signal to determine if an infection is indicated. Other embodiments are also included herein.

    摘要翻译： 本发明涉及用于检测与可植入医疗装置相关的感染的系统，装置和方法。 在一个实施例中，本发明包括检测患者感染的方法，包括在多个时间点使用长期植入的传感器测量生理参数，并评估生理参数测量以确定是否指示感染。 在一个实施例中，本发明包括可植入医疗装置，其包括被配置为产生对应于生理参数的第一信号的第一长期可植入传感器和设置在壳体内的控制器，所述控制器被配置为评估第一生理参数信号以确定是否 表示感染。 本文还包括其它实施例。

    Extendable/retractable fixation lead with distal travelling seal and related devices
    58.
    发明授权
    Extendable/retractable fixation lead with distal travelling seal and related devices 有权
    可扩展/可伸缩固定引线，远端行驶密封件和相关设备

    公开(公告)号：US08478429B2

    公开(公告)日：2013-07-02

    申请号：US13253345

    申请日：2011-10-05

    申请人： Joseph Walker ,  Ronald W. Heil, Jr. ,  G. Shantanu Reddy

    发明人： Joseph Walker ,  Ronald W. Heil, Jr. ,  G. Shantanu Reddy

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0575

    摘要： An implantable lead having a distal assembly including a coupler, a fixation helix secured to the coupler, a housing in which the fixation helix and the coupler are disposed, and a resilient seal that is fixedly secured to the coupler between proximal and distal ends thereof and able to translate with the coupler relative to the housing. The seal is positioned to sealingly engage an internal surface of the housing. When the coupler is translated such that the fixation helix is in a fully extended position, the seal is positioned to substantially seal off the housing to prevent tissue ingrowth.

    摘要翻译： 一种可植入引线，其具有远端组件，该远端组件包括耦合器，固定到耦合器的固定螺旋线，其中设置有固定螺旋和耦合器的壳体;以及弹性密封件，其在近端和远端之间固定地固定到耦合器， 能够与耦合器相对于壳体平移。 密封件被定位成密封地接合外壳的内表面。 当联接器平移以使得固定螺旋处于完全伸出位置时，密封件被定位成基本上密封壳体以防止组织向内生长。