Melanocortin Receptor-Specific Peptides for Treatment of Obesity / 669
    53.
    发明申请
    Melanocortin Receptor-Specific Peptides for Treatment of Obesity / 669 审中-公开
    黑皮质素受体特异性肽用于治疗肥胖/ 669

    公开(公告)号:US20090305960A1

    公开(公告)日:2009-12-10

    申请号:US12480420

    申请日:2009-06-08

    IPC分类号: A61K38/12 C07K7/64 A61P3/00

    CPC分类号: C07K7/54 A61K38/00 C07K7/06

    摘要: Melanocortin receptor-specific cyclic peptides of the formula where R1, R2, R3, R4, x and y are as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including obesity, diabetes, modulation of feeding behavior and related metabolic syndrome.

    摘要翻译: 其中R1,R2,R3,R4,x和y如说明书中所定义的组合物和制剂,包括上述式的肽的黑皮质素受体特异性环肽,以及预防,改善或治疗黑皮质素受体 - 介导的疾病,适应症,病症和综合症,包括肥胖症,糖尿病,调节摄食行为和相关的代谢综合征。

    Interface method, system, and program product for facilitating layering of a data communications protocol over an active message layer protocol
    55.
    发明授权
    Interface method, system, and program product for facilitating layering of a data communications protocol over an active message layer protocol 失效
    接口方法,系统和程序产品,用于促进通过活动消息层协议分层数据通信协议

    公开(公告)号:US07536468B2

    公开(公告)日:2009-05-19

    申请号:US10875471

    申请日:2004-06-24

    IPC分类号: G06F15/16 H04L12/28

    CPC分类号: H04L51/18 H04L69/22

    摘要: A protocol interface is provided for an active message protocol of a computing environment and a client process employing the active message protocol. The protocol interface includes an interface to a header handler function associated with the client process. The interface to the header handler function has parameters to be passed by and a parameter to be returned to the active message protocol when processing a message received through the active message protocol. The parameters to be passed include current message state information and current message type information for the received message. These parameters facilitate message-specific decisions by the header handler function about processing data of the message by the active message protocol. The parameter to be returned to the active message protocol instructs the active message protocol how to process the received message other than just where to store the message.

    摘要翻译: 为计算环境的活动消息协议和采用活动消息协议的客户端进程提供协议接口。 协议接口包括与客户端进程相关联的报头处理函数的接口。 在处理通过活动消息协议接收的消息时,头处理程序函数的接口具有要传递的参数和要返回到活动消息协议的参数。 要传递的参数包括接收到的消息的当前消息状态信息和当前消息类型信息。 这些参数有助于报头处理函数关于通过活动消息协议处理消息的数据的消息特定决定。 要返回到活动消息协议的参数指示活动消息协议如何处理接收到的消息,而不仅仅是存储消息的位置。

    METHOD AND SYSTEM FOR GENERATING SPECIFIC SEGMENTS OF A PROGRAM
    56.
    发明申请
    METHOD AND SYSTEM FOR GENERATING SPECIFIC SEGMENTS OF A PROGRAM 审中-公开
    用于产生程序的特定部分的方法和系统

    公开(公告)号:US20090019498A1

    公开(公告)日:2009-01-15

    申请号:US10596702

    申请日:2004-12-14

    IPC分类号: H04N7/087

    摘要: The present invention provides a method for creating a specific segment during broadcasting program. Firstly, sending a program to an user terminal; then receiving a request of an user from the user terminal, which requests to create a specific segment, wherein the specific segment is part of the broadcasting program; finally creating the specific segment according to the request. Furthermore, the invention can also send the created specific segment to the user terminal. The invention solves the problem that the choice standard for the specific segment specified by the broadcasting program supplier/the program producer does not meet the real requirement of the users, thereby the users can obtain their required specific segments during watching program to satisfy their individual needs.

    摘要翻译: 本发明提供了一种用于在广播节目期间创建特定片段的方法。 首先,向用户终端发送程序; 然后从请求创建特定段的用户终端接收用户的请求,其中特定段是广播节目的一部分; 最后根据要求创建具体的段。 此外,本发明还可以将创建的特定段发送到用户终端。 本发明解决了由广播节目供应商/节目制作者指定的特定片段的选择标准不符合用户实际需要的问题,用户可以在观看节目期间获得所需的特定片段以满足其个人需要 。

    Roll Profile for Both Shape Control and Free Ruled Rolling
    57.
    发明申请
    Roll Profile for Both Shape Control and Free Ruled Rolling 有权
    两种形状控制和自由滚动滚动轮廓

    公开(公告)号:US20080163659A1

    公开(公告)日:2008-07-10

    申请号:US11909263

    申请日:2006-03-24

    IPC分类号: B21B37/28

    摘要: Disclosed herein is a roll profile for work rolls for both shape control and free ruled rolling. Each of the work rolls has a tapered end. Providing starting point of the tapered end of the rolls being origin of coordinates, the curve of respective tapered end is a quartic curve represented by a formula y(x)=a0+a1x+a2x2+a3x3+a4x4, xε[0,Le], y(x)ε[0,He]. Because the transition between the tapered end and the roll body is smooth, asymmetric deformation due to the difference between abrasion of the upper and lower rolls is eliminated, which reducing wedged shape of strip and reducing unstable rolling due to asymmetrical strip stresses caused by the axial shifting of the roll. Further, as the axial shifting of the work roll is represented by Shift=B/2+Le−Se−Lw/2 so that box shaped abrasion of conventional roll is eliminated and closed type abrasion of conventional roll is changed into open type abrasion, which averaging the abrasion of the rolls, eliminating “cat ear” hole, achieving flat roll type rolling, and fulfilling the equipment of free ruled rolling.

    摘要翻译: 本文公开了用于形状控制和自由滚动的工作辊的辊轮廓。 每个工作辊都有一个锥形端。 提供辊的锥形端的起点是坐标的原点,各个锥形端的曲线是由公式y(x)= a 0 0 + a 1表示的四次曲线, / SUB> x + a 2 4,x 4,xepsilon [0,Le],y(x)ε[0,He]。 由于锥形端部与辊体之间的过渡是平滑的,因此消除了由于上下辊的磨损之间的差异导致的不对称变形,这减小了带状的楔形形状,并且由于由轴向引起的不对称带状应力而减少不稳定的轧制 卷的移动。 此外,随着工作辊的轴向移动由Shift = B / 2 + Le-Se-Lw / 2表示,从而消除了常规辊的箱形磨损,并将常规辊的封闭式磨损变为开式磨损, 平均轧辊磨损,消除“猫耳”孔,实现平辊轧制,实现自由轧制设备。

    Fused heterobicyclic kinase inhibitors
    60.
    发明申请
    Fused heterobicyclic kinase inhibitors 审中-公开
    融合的杂双环激酶抑制剂

    公开(公告)号:US20070208053A1

    公开(公告)日:2007-09-06

    申请号:US11654814

    申请日:2007-01-18

    IPC分类号: C07D471/02 A61K31/4745

    CPC分类号: C07D471/04

    摘要: Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X5, X7, R1, and Q1 are defined herein, inhibit kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer. The compounds are also useful in the treatment of inflammation, allergy, asthma, disease and conditions of the immune system, disease and conditions of the nervous system, cardiovascular diseases, disease and conditions of the eye, dermatological diseases, osteoporosis, diabetes, multiple sclerosis, and infections.

    摘要翻译: 下式的化合物及其药学上可接受的盐,其中X 1,X 2,X 3,X 4, X 5,X 5,X 7,R 1和Q 1 在本文中定义,抑制激酶,并且可用于治疗和/或预防过度增殖性疾病如癌症。 该化合物还可用于治疗炎症,过敏,哮喘,免疫系统的疾病和状况,神经系统的疾病和状况,心血管疾病,眼睛疾病和病症,皮肤病,骨质疏松症,糖尿病,多发性硬化 和感染。