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    METHOD OF FORMING A CERMET-CONTAINING BUSHING FOR AN IMPLANTABLE MEDICAL DEVICE HAVING A CONNECTING LAYER
    51.
    发明申请
    METHOD OF FORMING A CERMET-CONTAINING BUSHING FOR AN IMPLANTABLE MEDICAL DEVICE HAVING A CONNECTING LAYER 有权
    为具有连接层的可植入医疗装置形成包含母线的方法

    公开(公告)号：US20150122875A1

    公开(公告)日：2015-05-07

    申请号：US14593637

    申请日：2015-01-09

    申请人： HERAEUS PRECIOUS METALS GMBH & CO. KG

    发明人： Goran Pavlovic ,  Jeremy Glynn

    IPC分类号： A61N1/375 ,  B23K1/00

    CPC分类号： A61N1/3752 ,  A61N1/3754 ,  B23K1/0008 ,  B23K1/0016 ,  Y10T29/49227

    摘要： One aspect relates method of forming an electrical bushing for an implantable medical device, including generating at least one base body green compact for at least one base body from an insulating composition of materials. At least one cermet-containing conducting element green compact is formed for at least one conducting element. At least one conducting element green compact is introduced into the base body green compact. The insulation element green compact is connected to the at least one base body green compact in order to obtain at least one base body having at least one conducting element. A connecting layer is applied onto the at least one conducting element.

    摘要翻译： 一个方面涉及形成用于可植入医疗装置的电气衬套的方法，包括从绝缘材料组合物产生用于至少一个基体的至少一个基体生坯。 为至少一个导电元件形成至少一个含金属陶瓷的导电元件生坯。 至少一个导电元件绿色压块被引入基体绿色压块中。 绝缘元件生坯被连接到至少一个基体生坯上，以便获得至少一个具有至少一个导电元件的基体。 连接层施加到至少一个导电元件上。

    Electrical bushing for an implantable medical device
    52.
    发明授权
    Electrical bushing for an implantable medical device 有权
    用于可植入医疗器械的电气套管

    公开(公告)号：US08929987B2

    公开(公告)日：2015-01-06

    申请号：US12850412

    申请日：2010-08-04

    申请人： Jens Troetzschel ,  Heiko Specht

    发明人： Jens Troetzschel ,  Heiko Specht

    IPC分类号： A61N1/37 ,  A61N1/375

    CPC分类号： A61N1/3754

    摘要： One aspect relates to an electrical bushing for an implantable medical device, having an annulus-like holding element for holding the electrical bushing in the implantable medical device, whereby the holding element includes a through-opening, at least one elongated conducting wire extends through the through-opening, and an insulation element for forming a hermetic seal between the holding element and the conducting wire is arranged in the through-opening. One aspect provides for a cermet-containing bearing element to be arranged between the insulation element and the conducting wire.

    摘要翻译： 一个方面涉及一种用于可植入医疗装置的电气衬套，其具有用于将电气套管保持在可植入医疗装置中的环状保持元件，由此保持元件包括通孔，至少一根细长导电线延伸通过 并且在通孔中布置用于在保持元件和导线之间形成气密密封的绝缘元件。 一个方面提供一种用于设置在绝缘元件和导线之间的含金属陶瓷的轴承元件。

    HEAD PART FOR AN IMPLANTABLE MEDICAL DEVICE
    53.
    发明申请
    HEAD PART FOR AN IMPLANTABLE MEDICAL DEVICE 有权
    可植入医疗器械的头部

    公开(公告)号：US20140262494A1

    公开(公告)日：2014-09-18

    申请号：US14293596

    申请日：2014-06-02

    申请人： Heraeus Precious Metals GmbH & Co. KG

    发明人： Andreas Reisinger ,  Jeremy Glynn

    IPC分类号： H01R13/52 ,  H01R24/58 ,  H01R43/20

    CPC分类号： H01R13/5224 ,  A61M1/12 ,  A61M1/127 ,  A61N1/3752 ,  A61N1/3754 ,  H01R24/58 ,  H01R43/20 ,  H01R2201/12 ,  Y10T29/49169

    摘要： An electrical bushing for use in a housing of an implantable medical device is proposed. The electrical bushing includes at least one electrically insulating base body and at least one electrical conducting element. The conducting element establishes, through the base body, at least one electrically conductive connection between an internal space of the housing and an external space. The conducting element is hermetically sealed with respect to the base body, at least in part. The at least one conducting element includes at least one cermet. The electrical bushing includes at least one head part. The head part includes at least one plug connector element that enables electrical connection of at least one plug element from the external space to the plug connector element.

    摘要翻译： 提出了用于可植入医疗装置的壳体中的电气套管。 电气套管包括至少一个电绝缘基体和至少一个导电元件。 导电元件通过基体设置在壳体的内部空间与外部空间之间的至少一个导电连接。 导电元件至少部分地相对于基体气密地密封。 至少一个导电元件包括​​至少一个金属陶瓷。 电气衬套包括至少一个头部。 头部包括至少一个插头连接器元件，其能够使至少一个插头元件从外部空间电连接到插头连接器元件。

    Oxidation catalyst
    55.
    发明授权
    Oxidation catalyst 有权
    氧化催化剂

    公开(公告)号：US08753999B2

    公开(公告)日：2014-06-17

    申请号：US12499442

    申请日：2009-07-08

    申请人： Uwe Endruschat ,  Ansgar Wille ,  Prasanna Rajagopalan

    发明人： Uwe Endruschat ,  Ansgar Wille ,  Prasanna Rajagopalan

    IPC分类号： B01J23/00 ,  B01J23/10 ,  C01G37/14 ,  C01G23/00

    CPC分类号： B01D53/944 ,  B01D2255/206 ,  B01D2255/20707 ,  B01D2257/702 ,  B01J23/002 ,  B01J23/26 ,  B01J23/6522 ,  B01J35/04 ,  B01J37/03 ,  B01J2523/00 ,  F01N3/103 ,  F01N13/16 ,  F01N2330/06 ,  F01N2330/12 ,  Y02A50/2341 ,  B01J2523/3712 ,  B01J2523/47 ,  B01J2523/67 ,  B01J2523/31 ,  B01J2523/824

    摘要： A catalyst for selective oxidation of hydrocarbons relative to carbon monoxide includes a mixed oxide based on the compound Ce0.1-0.5Ti0.2-0.8Cr0.1-0.5Ox, wherein x is (the total of the valences of the metals)/2. Preferably, the mixed oxide is fixed as a coating on a molded body or less than 0.5 wt. % precious metal is doped to the mixed oxide. Oxidizable exhaust-gas components are oxidized for exhaust-gas purification by a mixed oxide based on the compound Ce0.1-0.5Ti0.2-0.8Cr0.1-0.5Ox as the catalyst. Preferably, hydrocarbons are preferentially oxidized relative to carbon monoxides or nitrogen oxides. For producing an oxidation catalyst for internal combustion engines, a mixed oxide made of cerium oxide, titanium oxide, chromium oxide, and optionally other metal oxides is fixed to a metallic or oxide or carbide, high temperature-stable molded body or an oxide ceramic, wherein the oxide ceramic is fixed to a molded body. Preferably, here the molded body is a wire mesh or a honeycomb structure, or the oxide ceramic on which the mixed oxide is fixed is a wash coat. Within a combustion chamber and an exhaust-gas pipe or exhaust-gas return pipe connected to this combustion chamber, a mixed oxide is fixed based on cerium oxide, titanium oxide, and chromium oxide as an oxidation catalyst.

    摘要翻译： 相对于一氧化碳选择性氧化烃的催化剂包括基于化合物Ce0.1-0.5Ti0.2-0.8Cr0.1-0.5Ox的混合氧化物，其中x是（金属价态的总和）/ 2。 优选地，将混合氧化物作为涂层固定在成型体上或小于0.5wt。 贵重金属被掺杂到混合氧化物中。 基于化合物Ce0.1-0.5Ti0.2-0.8Cr0.1-0.5Ox作为催化剂，通过混合氧化物氧化可氧化废气组分进行废气净化。 烃优选相对于一氧化碳或氮氧化物被优先氧化。 为了制造用于内燃机的氧化催化剂，将由氧化铈，氧化钛，氧化铬和任选的其它金属氧化物制成的混合氧化物固定在金属或氧化物或碳化物，高温稳定成型体或氧化物陶瓷上， 其中所述氧化物陶瓷固定在成形体上。 优选地，成型体是金属丝网或蜂窝结构体，或其上固定有混合氧化物的氧化物陶瓷是洗涂层。 在与该燃烧室连接的燃烧室和排气管或排气回流管内，作为氧化催化剂，以氧化铈，氧化钛，氧化铬为固定的混合氧化物。

    ELECTRICAL BUSHING WITH GRADIENT CERMET
    57.
    发明申请
    ELECTRICAL BUSHING WITH GRADIENT CERMET 有权
    电梯与电梯

    公开(公告)号：US20140008121A1

    公开(公告)日：2014-01-09

    申请号：US14023096

    申请日：2013-09-10

    申请人： Heraeus Precious Metals GmbH & Co. KG

    发明人： Jens Troetzschel ,  Goran Pavlovic ,  Harald Manhardt ,  Nicole Staudt

    IPC分类号： H02G3/22 ,  B29C71/02 ,  H02G1/00

    CPC分类号： H02G3/22 ,  B28B1/00 ,  B28B11/24 ,  B29C71/02 ,  H02G1/00 ,  H02G3/18 ,  Y10T29/49117 ,  Y10T29/49158 ,  Y10T29/49163

    摘要： One aspect relates to a method for producing an electrical bushing for an implantable device, an electrical bushing, and an implantable device. The method according to one embodiment includes forming a base body from a ceramic slurry and introducing a bushing conductor made of a metal or cermet material with a metal fraction into the base body. The metal fraction in the bushing conductor is provided to decrease towards the base body. It includes sintering the green blank that includes the base body and the bushing conductor.

    摘要翻译： 一个方面涉及一种用于生产用于可植入装置的电气套管，电气衬套和可植入装置的方法。 根据一个实施例的方法包括从陶瓷浆料形成基体，并将由金属或金属陶瓷材料制成的套管导体与金属部分引入基体。 衬套导体中的金属部分设置成朝向基体减小。 它包括烧结包括基体和套管导体的绿色坯料。

    Method for production of a medical marker
    58.
    发明授权
    Method for production of a medical marker 有权
    医用标记物的制造方法

    公开(公告)号：US08597872B2

    公开(公告)日：2013-12-03

    申请号：US12641814

    申请日：2009-12-18

    申请人： Heiko Specht ,  Frank Krüger

    发明人： Heiko Specht ,  Frank Krüger

    IPC分类号： G03F7/20

    CPC分类号： A61M25/0012 ,  A61B90/39 ,  A61B2017/00526 ,  A61M25/0108

    摘要： A method is provided for production of a medical marker (4) made of an X-ray-opaque material, including the following steps: a) photolithographic application of a mask (31) on a substrate (1); b) deposition of the X-ray-opaque material (40) of the marker (4) on the substrate (1); c) removal of the mask (31); and d) elimination of the substrate (1).

    摘要翻译： 提供了一种用于生产由X射线不透明材料制成的医疗标记物（4）的方法，包括以下步骤：a）在基底（1）上光刻地施加掩模（31）; b）将标记物（4）的X射线不透明材料（40）沉积在基底（1）上; c）去除面罩（31）; 和d）消除基底（1）。

    Process for the production of bendamustine alkyl ester, bendamustine, and derivatives thereof
    60.
    发明授权
    Process for the production of bendamustine alkyl ester, bendamustine, and derivatives thereof 有权
    苯达莫司汀烷基酯，苯达莫司汀及其衍生物的生产方法

    公开(公告)号：US08481751B2

    公开(公告)日：2013-07-09

    申请号：US13334402

    申请日：2011-12-22

    申请人： Kai Groh ,  Holger Rauter ,  Dirk Born

    发明人： Kai Groh ,  Holger Rauter ,  Dirk Born

    IPC分类号： C07D235/12

    CPC分类号： C07D235/12 ,  C07C227/16 ,  C07C227/18 ,  C07C229/42

    摘要： Methods are provided for the production of bendamustine alkyl ester, bendamustine, as well as derivatives thereof. With the methods the production of these compounds is possible in reproducibly high yields. To this end, hydroxyl-group-containing esters are used as the starting material, whose hydroxyl groups are substituted in a simple way by halogen groups. This substitution is possible in the presence of (i) oxalyl chloride and (ii) dialkylformamide, dialkyl acetamide or dimethyl sulfoxide. In a subsequent reaction, the resulting esters can be hydrolyzed to form the acid.

    摘要翻译： 提供了用于生产苯达莫司汀烷基酯，苯达莫司汀及其衍生物的方法。 通过这些方法，这些化合物的生产可以以高产率重现。 为此，使用含羟基的酯作为原料，其羟基以简单的方式被卤素取代。 在（i）草酰氯和（ii）二烷基甲酰胺，二烷基乙酰胺或二甲基亚砜的存在下，该取代是可能的。 在随后的反应中，所得的酯可以水解形成酸。