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公开(公告)号：US11867597B2
公开(公告)日：2024-01-09
申请号：US17677298
申请日：2022-02-22
Inventor： Nikhil Bhalla , Amy Shen Fried , Kang-Yu Chu
IPC: G01N21/75 , G01N33/543 , C03C17/09 , G01N21/552 , G01N21/41
CPC classification number: G01N33/54373 , C03C17/09 , G01N21/554 , C03C2217/255 , C03C2218/151 , C03C2218/33 , G01N21/41
Abstract: A method for making a plasmonic mushroom array includes: forming a plurality of metal nano-islands each having nanometer-range dimensions on a surface of a glass substrate; and subjecting to the glass substrate having the plurality of metal nano-islands formed thereon to reactive ion etching such that the plurality of metal nano-islands are converted to a plurality of mushroom-shaped structures each having a metal cap supported by a pillar made of a material of the glass substrate and each having dimensions smaller than the dimensions of the nano-islands, the plurality of mushroom-shaped structures being arranged in a substantially regular pattern with intervals smaller than average intervals between the nano-islands, thereby forming the plurality of nano-scale mushroom-shaped structures on the glass substrate that can exhibit localized surface plasmon resonance.
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52.发明公开公开(公告)号：US20230231118A1
公开(公告)日：2023-07-20
申请号：US18011357
申请日：2021-09-07
Inventor： Panagiotis GRAMMATIKOPOULOS , Marta HARO , Junlei ZHAO , Emilio Jose JUAREZ-PEREZ
IPC: H01M4/38 , H01M4/134 , H01M4/04 , H01M4/1395
CPC classification number: H01M4/386 , H01M4/134 , H01M4/0471 , H01M4/1395 , H01M4/0423 , H01M2004/027
Abstract: A composite nanoarchitecture unit is disclosed. The unit comprises a columnar film grown on top of another layer where the columns touch each other at the top forming arches having optimized characteristics. This nanoarchitecture unit, called nano-vault, achieves high mechanical stability for films under strong and variable stress action.
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公开(公告)号：US11677206B2
公开(公告)日：2023-06-13
申请号：US16806874
申请日：2020-03-02
Inventor： Yuimaru Kubo , Jason Robert Ball , Petr Moroshkin , Denis Konstantinov
IPC: H01S1/02
CPC classification number: H01S1/02
Abstract: Embodiments of the microwave amplification system are described. In an embodiment, a microwave amplification system includes a microwave amplifier that contains a paramagnetic material with an impurity. The impurity has a plurality of nuclear spin and electron spin-based energy levels. The system includes an input to receive a pumping signal which is transmitted to the microwave amplifier to cause a population inversion in the impurity and excite it to one of the nuclear spin and electron spin-based energy levels. The system further includes another input to receive an input signal to be amplified by the microwave amplifier, the input signal having a lower power than the pumping signal. Once transmitted to the microwave amplifier, the input signal is amplified by the excited state of the impurity in the microwave amplifier thereby generating an amplified signal.
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公开(公告)号：US11645574B2
公开(公告)日：2023-05-09
申请号：US16130482
申请日：2018-09-13
Inventor： Tomotake Sasaki , Eiji Uchibe , Kenji Doya , Hirokazu Anai , Hitoshi Yanami , Hidenao Iwane
CPC classification number: G06N20/00 , G06N3/006 , H04L41/0816 , H04L41/16 , H04L43/08
Abstract: A non-transitory, computer-readable recording medium stores therein a reinforcement learning program that uses a value function and causes a computer to execute a process comprising: estimating first coefficients of the value function represented in a quadratic form of inputs at times in the past than a present time and outputs at the present time and the times in the past, the first coefficients being estimated based on inputs at the times in the past, the outputs at the present time and the times in the past, and costs or rewards that corresponds to the inputs at the times in the past; and determining second coefficients that defines a control law, based on the value function that uses the estimated first coefficients and determining input values at times after estimation of the first coefficients.
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公开(公告)号：US20210291159A1
公开(公告)日：2021-09-23
申请号：US16614836
申请日：2018-05-18
Inventor： Kazumi Toda-Peters , Amy Shen Fried , Shivani Sathish , Doojin Lee , Casey James Galvin , Kei Funakoshi
Abstract: An integrated system for sampling and processing a liquid suspension, the system comprising: a cartridge member comprising a sampling port on a first end of the cartridge member, a second one-way valve in communication with the sampling port, a stopper at a second end of the cartridge member, and a fluid chamber between the second one-way valve and the stopper; a body member having a first end configured to accept the first end of the cartridge member and a second end opposite the first end of the body member; and a cap unit disposed on the second end of the body member, the cap unit comprising a wash chamber, wherein the cap unit comprises a first one-way valve between the second end of the body member and the wash chamber and a filter between the first one-way valve and the wash chamber or a filter between the second end of the body member and the wash chamber and a first one-way valve between the filter and the wash chamber.
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Patent Agency Ranking
公开(公告)号：US20210276954A1
公开(公告)日：2021-09-09
申请号：US17212514
申请日：2021-03-25
Inventor： Fujie TANAKA , Feng YIN
IPC: C07D209/54 , C07C201/12 , C07C205/51 , C07D207/16
Abstract: The present invention relates to a process for preparing 3-pyrrolidine carboxylic acid derivatives, and particularly a simple process for preparing 5-substituted 3-pyrrolidine carboxylic acid derivatives. In addition, the present invention relates to a novel pyrrolidine carboxylic acid derivative, its manufacture, pharmaceutical compositions containing it and its use as a catalyst.
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公开(公告)号：US10995119B2
公开(公告)日：2021-05-04
申请号：US16067764
申请日：2017-01-06
Inventor： Toshifumi Akizawa , Tadashi Yamamoto
Abstract: The present invention provides a novel molecule that catalyzes a hydrolysis reaction and is different from enzyme proteins. The catalytic peptide according to the present invention is a catalytic peptide that catalyzes a hydrolysis reaction, including at least one peptide selected from the group consisting of the following peptides (A1) to (A4): (A1) a peptide consisting of Box A and at least one of an upstream region and a downstream region therefrom in a Tob/BTG protein; (A2) a peptide consisting of a partial region of the peptide (A1); (A3) a peptide that consists of an amino acid sequence obtained by deletion, substitution, addition, and/or insertion of one or more amino acids in an amino acid sequence of the peptide (A1) or (A2) and has hydrolysis activity; and (A4) a peptide consisting of an amino acid sequence with a sequence identity of at least 85% to the amino acid sequence of the peptide (A1) or (A2) and having hydrolysis activity.
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公开(公告)号：US10896382B2
公开(公告)日：2021-01-19
申请号：US15329690
申请日：2015-08-07
Inventor： Eiji Uchibe , Kenji Doya
Abstract: A method of inverse reinforcement learning for estimating cost and value functions of behaviors of a subject includes acquiring data representing changes in state variables that define the behaviors of the subject; applying a modified Bellman equation given by Eq. (1) to the acquired data: q(x)+gV(y)−V(x)=−ln{pi(y|x))/(p(y|x)} (1) where q(x) and V(x) denote a cost function and a value function, respectively, at state x, g represents a discount factor, and p(y|x) and pi(y|x) denote state transition probabilities before and after learning, respectively; estimating a density ratio pi(y|x)/p(y|x) in Eq. (1); estimating q(x) and V(x) in Eq. (1) using the least square method in accordance with the estimated density ratio pi(y|x)/p(y|x), and outputting the estimated q(x) and V(x).
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公开(公告)号：US10851337B2
公开(公告)日：2020-12-01
申请号：US15759734
申请日：2016-09-16
Inventor： Hsieh-Fu Tsai , Amy Shen Fried , Ji-Yen Cheng
Abstract: A disclosed insert for a circular-shaped petri dish can generate a substantially uniform electric field across the petri dish that is filled with a fluid establishing a salt bridge. The insert includes a circular-shaped bottom plate defining a circular-shaped space; a side channel vertically erecting from a circular periphery of said bottom plate; and a pair of current rectifying chambers each having a generally planar shape communicating with the side channel. In at least some aspects of the invention, portions of the side channel bridging the pair of current rectifying chambers each have a generally concave top profile having a lowest point at the center between the pair of current rectifying chambers such that, when the salt bridge is established, the circular-shaped space defined by the bottom plate exhibits a substantially uniform electric field in a substantially entire area of the space.
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60.发明申请公开(公告)号：US20190393532A1
公开(公告)日：2019-12-26
申请号：US16480848
申请日：2018-02-27
Inventor： Geoffrey Kellogg SCHAFFER-HARRIS , Viacheslav FEDOROVICH , Igor GORYANIN , Lukasz Michal SZYDLOWSKI , David James Wilpault SIMPSON , Georgy FILONENKO
Abstract: The present invention relates to a process for preparing a supported catalytic material, wherein the said process comprises a step of heating a precursor of support material which has been impregnated with a mixture of chemical precursors, wherein the said mixture includes a nitrogen-containing reducing reagent as a precursor and a transition-metal-containing compound as a precursor.
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