公开(公告)号：US20150032082A1

公开(公告)日：2015-01-29

申请号：US14344581

申请日：2012-09-12

申请人： Masatake Kudoh

发明人： Masatake Kudoh

IPC分类号： A61M5/30

CPC分类号： A61M5/30 ,  A61M5/2046 ,  A61M5/3007 ,  A61M2005/3132

摘要： A needleless syringe comprises an enclosing unit for an injection objective substance, a pressurizing unit for the injection objective substance, a discharge unit having a flow passage for allowing the injection objective substance to flow therethrough so that the injection objective substance is discharged from an open end of the flow passage to an injection target area, the open end being formed so that an area thereof is smaller than a flow passage area of the enclosing unit, and a minute pore unit including a minute pore having a flow passage area smaller than the area of the open end of the discharge unit and which is arranged on an outer side of the open end so that the injection objective substance discharged from the open end passes through the minute pore and arrives at a side of the injection target area.

摘要翻译： 无针注射器包括用于注射目标物质的封闭单元，用于注射物镜物质的加压单元，具有用于允许注射物质流过其中的流动通道的排出单元，使得注射物质从开口端排出 所述开口端形成为使得其面积小于所述封闭单元的流路面积，并且所述微孔单元包括具有小于所述区域的流路面积的微孔 并且其布置在开口端的外侧，使得从开口端排出的注入物质物质通过微孔并到达注射目标区域的一侧。

公开(公告)号：US08905975B2

公开(公告)日：2014-12-09

申请号：US12441043

申请日：2007-09-12

申请人： Frédéric Perot

发明人： Frédéric Perot

IPC分类号： A61M5/00 ,  A61M37/00 ,  A61M5/28 ,  A61M5/31 ,  A61M5/315

CPC分类号： A61M5/31591 ,  A61M5/284 ,  A61M5/3146 ,  A61M5/31555 ,  A61M5/3158 ,  A61M5/31595 ,  A61M2005/3132 ,  A61M2005/31508

摘要： The present invention relates to a container comprising: a body; a pusher movable with respect to the body between an initial position and an end-of-use position; a locker located on the pusher and forming an abutment so as to be able to abut against the body between the initial position and the end-of-use position, wherein, the abutment abuts against the body to limit distal movement of the pusher relative to the body to a pusher locking position located between the initial position and the end-of-use position; a locking arrangement capable of, temporarily, locking the locker on the pusher so as to define a locker locking position of the locker on the pusher, the locker locking position establishing the position of the abutment relative to the pusher so as to set the pusher locking position; and, an unlocking arrangement designed so that, with triggering, the locking arrangement is released so as to allow the locker to be displaced relative to the pusher and for the pusher to be moved past the pusher locking position toward the end-of-use position.

摘要翻译： 本发明涉及一种容器，包括：主体; 在初始位置和使用终点之间相对于主体移动的推动器; 位于推动器上的储物柜，并形成一个邻接部，以便能够在初始位置和使用终点位置之间抵靠身体，其中，邻接部抵靠身体以限制推动器相对于主体的远端运动 身体到位于初始位置和使用终点位置之间的推动器锁定位置; 锁定装置，其能够暂时将锁定件锁定在推动器上，以便将锁定件锁定在推动器上，锁定位置确定支座相对于推动器的位置，以便将推动器锁定 位置; 以及解锁装置，其被设计成使得随着触发而释放锁定装置，以便允许储物柜相对于推动器移位，并且推动器能够移动通过推动器锁定位置朝向使用终点位置 。

公开(公告)号：US20140288484A1

公开(公告)日：2014-09-25

申请号：US14285261

申请日：2014-05-22

申请人： Ceramatec, Inc.

发明人： Ashok V. Joshi ,  James Steppan ,  Jesse Nachlas ,  Kieran Murphy

IPC分类号： A61M5/31

CPC分类号： A61M5/3129 ,  A61B17/3478 ,  A61B2017/00261 ,  A61M5/286 ,  A61M5/31511 ,  A61M37/00 ,  A61M2005/006 ,  A61M2005/3132 ,  A61M2202/0216 ,  C01B13/02 ,  C01B13/10 ,  C25B1/13

摘要： An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having an ozone generator associated therewith. The generator is initiated and a therapeutic gas is accumulated within the barrel, at which point it can be delivered from the barrel into a target site via a needle, thereby delivering therapeutic effects to that target site.

摘要翻译： 提供了一种用于施用治疗剂的装置。 在各种实施例中，该装置包括具有镜筒和柱塞并且具有与其相关联的臭氧发生器的注射器。 引发发生器并且治疗气体积聚在枪管内，此时它可以通过针从枪管输送到目标部位，从而将治疗效果传递给目标部位。

公开(公告)号：US08784371B2

公开(公告)日：2014-07-22

申请号：US12441944

申请日：2007-08-31

申请人： Patrick Alexandre

发明人： Patrick Alexandre

IPC分类号： A61M5/30 ,  A61M37/00 ,  A61M5/31 ,  A61M5/28 ,  A61M5/20

CPC分类号： A61M5/30 ,  A61M5/2046 ,  A61M2005/287 ,  A61M2005/3132

摘要： Needleless injection device (1) comprising a gas generator (2), a reservoir (5) in the form of a glass tube (6) closed by an upstream stopper (7) and a downstream stopper (8) between which a liquid active principle (9) is accommodated, and an injection nozzle (15) equipped with a receptacle (19) and with at least one peripheral injection conduit (20), said tube (6) having, at one of its ends, a flange (4) via which it is in contact with said nozzle (15). The main feature of this needleless injection device (1) is that the tube (6) has a cylindrical inner channel with an upstream part (21) which is continued by a downstream part (22) of smaller diameter, said downstream part (22) being surrounded by said flange (4) and opening into the receptacle (19).

摘要翻译： 无针注射装置（1），包括气体发生器（2），由上游止动件（7）封闭的玻璃管（6）形式的储存器（5）和下游止动件（8），液体活性成分 （9），以及配备有容器（19）和至少一个外围注射管道（20）的注射嘴（15），所述管（6）的一端具有凸缘（4） 通过它与所述喷嘴（15）接触。 该无针注射装置（1）的主要特征在于，管（6）具有圆柱形内通道，其上游部分（21）由较小直径的下游部分（22）连续，所述下游部分（22） 被所述凸缘（4）包围并且通向所述容器（19）。

公开(公告)号：US08579855B2

公开(公告)日：2013-11-12

申请号：US13159346

申请日：2011-06-13

申请人： Byeong Seon Chang ,  Roger Wongjung Liu

发明人： Byeong Seon Chang ,  Roger Wongjung Liu

IPC分类号： A61M37/00 ,  A61M31/00

CPC分类号： A61M5/31 ,  A61J1/2096 ,  A61M5/2448 ,  A61M5/31596 ,  A61M5/3294 ,  A61M5/34 ,  A61M5/345 ,  A61M2005/312 ,  A61M2005/3128 ,  A61M2005/3132 ,  A61M2005/31598

摘要： A method of storing and delivery a drug, such as by lyophilizing and reconstituting, comprises performing both storing and delivering with the same container closure assembly. The container closure is assembled in a preparation configuration during which lyophilization occurs. After lyophilizing, the powdered drug is forced into a spiral channel in the container closure assembly by a plunger. The plunger leaves substantially no head space for the powdered drug, and the assembly is sealed thereby now being in the storage configuration. For delivery of the stored powdered drug, a syringe of diluent is introduced to the container assembly thereby changing the assembly to the delivery configuration. The spiral channel is continuous between an input end and a delivery end with the delivery end being in fluid communication with a delivery outlet of the assembly. The assembly includes a diluent flow path that forces the diluent into a spiral channel at only the input end. As the diluent is forced to flow through the spiral channel from the input end to the delivery end, it reconstitutes the powdered drug, thereby reconstituting and delivering in the same step. No separate reconstituting and priming steps are needed.

摘要翻译： 存储和递送药物的方法，例如通过冻干和重构，包括使用相同的容器封闭组件进行存储和递送。 容器封闭件以制备结构组装，在此期间发生冻干。 冻干后，粉末状药物通过柱塞被迫进入容器封闭组件中的螺旋通道。 柱塞基本上没有用于粉末状药物的顶部空间，并且组件被密封，从而现在处于储存结构。 为了输送储存的粉末药物，将稀释剂的注射器引入容器组件，从而将组件改变为输送构型。 螺旋通道在输入端和输送端之间是连续的，其中输送端与组件的输送出口流体连通。 组件包括稀释剂流动路径，其仅在输入端将迫使稀释剂进入螺旋通道。 当稀释剂被迫从输入端流到输送端时，它重新构成粉末药物，从而在相同的步骤中重构和输送。 不需要单独的重组和启动步骤。

公开(公告)号：US20130090596A1

公开(公告)日：2013-04-11

申请号：US13703319

申请日：2011-06-08

申请人： Takashi Asai ,  Tsutomu Takahashi ,  Kenyu Ito ,  Atsushi Ishikawa

发明人： Takashi Asai ,  Tsutomu Takahashi ,  Kenyu Ito ,  Atsushi Ishikawa

IPC分类号： A61M5/315

CPC分类号： A61M5/31596 ,  A61M5/284 ,  A61M5/315 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/347 ,  A61M2005/3104 ,  A61M2005/3132

摘要： In a pre-filled syringe having an intermediate gasket, a liquid drug is enclosed in the second chamber located on the base end side with respect to the intermediate gasket while a powdered drug is enclosed in the first chamber located on the front end side with respect to the intermediate gasket. The intermediate gasket has at least two layers including a front end layer corresponding to a wall of the first chamber and a base end layer corresponding to a wall of the second chamber, and also has a low water-absorptive layer in the layer on the base end side with respect to the front end layer. The base end layer is formed of a material having low water-absorptivity and not lowering a pH of the liquid drug.

摘要翻译： 在具有中间垫圈的预填充注射器中，液体药物相对于中间垫圈封闭在位于基​​端侧的第二腔室中，同时粉末药物被封装在位于前端侧的第一腔室中 到中间垫圈。 中间垫圈具有至少两层，其包括对应于第一室的壁的前端层和对应于第二室的壁的基端层，并且在基体的该层中还具有低吸水层 相对于前端层的端侧。 基底层由具有低吸水性且不降低液体药物的pH的材料形成。

公开(公告)号：US08276581B2

公开(公告)日：2012-10-02

申请号：US12740067

申请日：2008-10-28

申请人： Hideaki Kawamura ,  Hiroshi Togashi

发明人： Hideaki Kawamura ,  Hiroshi Togashi

IPC分类号： A61M11/00

CPC分类号： A61M31/00 ,  A61M11/00 ,  A61M11/007 ,  A61M15/0036 ,  A61M15/004 ,  A61M15/08 ,  A61M2005/3132 ,  A61M2202/0468 ,  A61M2205/0222 ,  A61M2205/0238 ,  A61M2206/16 ,  B05B1/3436 ,  B05B11/02 ,  B05B11/3001

摘要： Provided is an easy-to-handle prefilled type nasal drip appliance which can spray medical solution surely into the nostril while holding down the production cost. A syringe barrel has a spray hole and a latching portion of a center stopper on one side, with a conduction portion of medical solution being provided at the latching portion, and has a portion protruding inward of the inner circumferential surface formed on the other end side. A plunger has a portion protruding outward of the outer circumferential surface formed substantially in the axial center wherein both protrusions engage with each other. When the plunger is moved in the spray direction of the syringe barrel to get over the plunger side protrusion and disengaged, the medical solution moves the center stopper in the spray direction to form a medical solution inflow groove between the conduction portion formed at the center stopper latching portion and the center stopper. Consequently, a medical solution storage portion and the spray hole are interconnected and the medical solution can be sprayed.

摘要翻译： 提供了一种易于处理的预充型鼻滴式器具，可以将药液固定在鼻孔内，同时降低生产成本。 注射器筒在一侧具有喷孔和中心止动器的闩锁部分，药液的导电部分设置在闩锁部分处，并且具有从形成在另一端侧的内周面向内突出的部分 。 柱塞具有大致在轴向中心形成的外周面向外突出的部分，其中两个突起彼此接合。 当柱塞在注射器筒的喷射方向上移动以越过柱塞侧突起并脱开时，医用溶液沿着喷射方向移动中心止动件，以在形成在中心塞的传导部分之间形成药液流入槽 闩锁部分和中心止动器。 因此，药液存储部和喷孔相互连接，能够喷射医用溶液。

公开(公告)号：US20120095394A1

公开(公告)日：2012-04-19

申请号：US13276273

申请日：2011-10-18

申请人： Makoto KAKIUCHI ,  Seiji SHIMAZAKI ,  Teruo MATSUDA

发明人： Makoto KAKIUCHI ,  Seiji SHIMAZAKI ,  Teruo MATSUDA

IPC分类号： A61M5/31

CPC分类号： A61M5/284 ,  A61M5/31505 ,  A61M5/31515 ,  A61M5/31583 ,  A61M5/347 ,  A61M2005/3132 ,  A61M2005/31508

摘要： A dual chamber combined container-syringe includes: an outer casing having a bypass portion; a hub lure lock; a front stopper; a middle stopper that seals a pharmaceutical preparation together with the front stopper; an end stopper that seals a liquid medicine together with the middle stopper; a finger grip; and a plunger rod that is connected to the end stopper from the rear end side, wherein a female screw portion twisted around an axis is formed on an inner peripheral surface of the finger grip, and a first male screw portion, a tip of which comes into contact with a rear end of the female screw portion and can be screwed into the female portion, and a first guide plate are formed on an outer peripheral surface of the plunger rod when a part of the middle stopper enters the bypass portion.

摘要翻译： 双室组合容器 - 注射器包括：具有旁路部分的外壳; 枢纽诱惑锁; 前挡块 中间塞子，与前止动器一起密封药物制剂; 止血塞，其与中间塞子一起密封药液; 手指握力 以及柱塞杆，其从后端侧连接到端部止动器，其中在手指的内周面上形成有围绕轴线扭转的阴螺纹部分，并且其顶端的第一阳螺纹部分 与内螺纹部分的后端接触，并且可以拧入阴部，当中间止挡件的一部分进入旁路部分时，在柱塞杆的外周面上形成有第一引导板。

公开(公告)号：US20110130727A1

公开(公告)日：2011-06-02

申请号：US12868940

申请日：2010-08-26

申请人： Mark A. Crawford ,  Marty L. Stout ,  Weston F. Harding

发明人： Mark A. Crawford ,  Marty L. Stout ,  Weston F. Harding

IPC分类号： A61M5/00

CPC分类号： A61M39/045 ,  A61M5/16831 ,  A61M5/284 ,  A61M2005/1402 ,  A61M2005/3132 ,  A61M2205/273 ,  A61M2205/583 ,  G09F3/0291 ,  Y10T436/2575

摘要： A vascular access device for communicating with the vascular system of a patient may include a status indicator. The status indicator may detect and signal that a period of time has elapsed in relation to the use of the vascular access device.

公开(公告)号：US20110046602A1

公开(公告)日：2011-02-24

申请号：US12598103

申请日：2008-05-01

申请人： Kevin Grimm ,  Lauren Marie Shafer ,  Travis Edward Snyder ,  Rachel Elise Zielinski ,  Daniel George Johnson

发明人： Kevin Grimm ,  Lauren Marie Shafer ,  Travis Edward Snyder ,  Rachel Elise Zielinski ,  Daniel George Johnson

IPC分类号： A61M5/19 ,  A61M5/28 ,  B23P11/00 ,  B65B1/04

CPC分类号： A61M5/284 ,  A61M5/142 ,  A61M5/31501 ,  A61M2005/3128 ,  A61M2005/3132 ,  Y10T137/0402

摘要： Improved fluid delivery devices and systems are disclosed, including drug delivery devices and systems, and methods that permit, inter alia, the rapid sequential delivery of two or more fluids to a single external fluid flow or intravenous line.

摘要翻译： 公开了改进的流体递送装置和系统，包括药物递送装置和系统，以及允许特别是将两种或多种流体快速顺序输送到单个外部流体流动或静脉内管线的方法。