公开(公告)号：US3812185A

公开(公告)日：1974-05-21

申请号：US4116170

申请日：1970-05-25

申请人： HOECHST AG

发明人： WEBER H ,  WEYER R ,  AUMUELLER W ,  MUTH K

IPC分类号： C07C311/59 ,  C07D333/38 ,  C07D333/70 ,  C07C127/00

CPC分类号： C07D333/38 ,  C07C311/59 ,  C07C2601/14 ,  C07C2601/18 ,  C07C2602/50 ,  C07C2603/66 ,  C07D333/70 ,  Y10S514/866

摘要： BENZENESULFONYL-UREAS HAVING HYPOGLYCEMIC ACTIVITIES CORRESPONDING TO THE FORMULA

1-(R1-NH-CO-NH-SO2-),4-(X-CO-NH-Y-)BENZENE

WHEREIN R1 IS (A) NOCRARAN-7-YL, BICYCLO- 3,1,0!-HEXYL, BICYCLO- 5, 1,0!-OCTYL, OR BICYCLO- 6,1,0!-NONYL; (B) 4,7-ENDOMETHYLENE - PERHYDROINDAN-5-YL; 4,7ENDOMETHYLENE-6-CHLORO-PERHYROINDAN-5-YL; 4,7ENDOMETHYLENE-PERHYDROINDAN - 2 YL; 2,6-ENDOMETHYLENECYCLOHEPTYL; 2,5-ENDOCYCLOBUTYLENE-1,2CYCLOHEXYL; EXO-TRICYCLO-(3,2,1,02,4)-OCTANYL; (C) SPIRO-(2-CYCLOPROPANE) - CYCLOPETYL; SPIRO-(2CYCLOBUTANE)-CYCLOPENTYL; SPIRO-(2-CYCLOPETANE)CYCLOPENTYL; SPIRO-(2-CYLOHEXANE)-CYCLOPENTYL; OR SPIRO-(5,5)-UNDECYL-3; X IS

A,A1-PHENYL OR 3-B,5-A1-THIEN-2-YL

IN WHICH A STANDS FOR HYDROGEN, HALOGEN, RIFLUOROMETHYL, PHENOXY, LOWER ALKYL OR LOWER ALKOXY BOTH HAVING 1-4 CARBON ATOMS, A1 STANDS FOR HYDROGEN, HALOGEN OR LOWER ALKYL OF 1-4 CARBON ATOMS AND B STANDS FOR HYDROGEN OR LOWER ALKOXY HOF 1-4 CARBON ATOMS Y IS A HYDROCARBON CHAIN OF 1-3 CARBON ATOMS OR A PHYSIOLOGICALLY TOLERABLE SALT THEREOF.

公开(公告)号：US3787491A

公开(公告)日：1974-01-22

申请号：US3787491D

申请日：1971-09-29

申请人： BRETSCHNEIDER H ,  GRASSMAYR K ,  GRUSSNER A ,  HOHENLOHE OEHRINGEN K

发明人： GRASSMAYR K ,  HOHENLOHE OEHRINGEN K ,  GRUSSNER A ,  BRETSCHNEIDER H

IPC分类号： A61K31/17 ,  C07C311/54 ,  C07C127/00

CPC分类号： A61K31/17 ,  C07C311/54 ,  Y10S514/866

摘要： A HYPOGLYCEMIC AGENT, 1-(P-TOLUENESULFONYL)3-(2-HYDROXY-3-BORNYL)-UREA, IS PREPARED, FOR EXAMPLE, FROM TOSYL ETHYL URETHANE AND 3-AMINO-BORNEOL OR 3-AMINO-ISOBORNEOL. ONE OF THE ISOMERS, I.E., 1-((1R)-2-ENDO-HYDROXY-3-ENDO-BORNYL) - 3 - (P-TOLYLSULFONYL)-UREA, IS PARTICULARLY USEFUL AS A HYPOGLYCEMIC AGENT.

公开(公告)号：US3776843A

公开(公告)日：1973-12-04

申请号：US3776843D

申请日：1971-06-14

申请人： ICI LTD

发明人： COTTRELL A ,  BRADFORD N ,  LOVETT T

IPC分类号： A62D1/00 ,  C07C127/00

CPC分类号： A62D1/0014

摘要： IMPROVED YIELDS OF FIRE-EXTINGUISHING COMPOUNDS HAVING THE EMPIRICAL FORMULA MC2N2H3O3 WERE M IS AN ALKALI METAL ARE OBTAINED BY REACTING UREA WITH AN ALKALI METAL HYDROXIDE, CARBONATE, BICARBONATE OR SESQUICARBONATE AT A TEMPERATURE OF BETWEEN 160*C. TO 200*C. AND IN CONTACT IWTH AN ATMOSPHERE CONTAINING AT LEAST 5% AND UP TO 50% BY VOLUME OF WATER VAPOR.

公开(公告)号：US3752851A

公开(公告)日：1973-08-14

申请号：US3752851D

申请日：1971-09-21

申请人： BOEHRINGER MANNHEIM GMBH

发明人： STACH K ,  SCHMIDT F ,  WINTER W ,  FAULAND E ,  AUMUELLER W

IPC分类号： C07D209/86 ,  C07D295/28 ,  C07D311/82 ,  C07D313/12 ,  C07D335/02 ,  C07D337/12 ,  C07D337/16 ,  C07C127/00

CPC分类号： C07D295/32 ,  C07C2603/18 ,  C07D209/86 ,  C07D311/82 ,  C07D313/12 ,  C07D335/02 ,  C07D337/12 ,  C07D337/16 ,  Y10S514/866

摘要： NOVEL SULFONYL UREAS HAVING THE FORMULA:

X
NH-R2)-(R1-1,2-PHENYLENE)-)

WHEREIN X REPRESENTS OXYGEN, SULFUR, SATURATED, UNSATURATED, STRAIGHT OR BRANCHED CHAIN ALKYLENE CONTAINING UP TO 3 CARBON ATOMS, OXYMETHYLENE, THIAMETHYLENE, THIAETHYLENE, IMINOMETHYLENE, ALKYLATED IMINOMETHYLENE, ACYLATED IMINOMETHYLENE, CARBOXIMIDO, ALKYLATED CARBOXIMIDO, OR A VALENCY BOND, R1 IS HYDROGEN, HALOGEN, ALKYL, ALKOXY OR TRIFLUOROMETHYL, Y IS SATURATED, UNSATURATED, STRAIGHT OR BRANCHED CHAIN ALKYLENE CONTAINING UP TO 6 CARBON ATOMS OR SUCH ALKYLENE GROUP CONTAINING A NITROGEN OR OXYGEN ATOM, Z IS STRAIGHT OR BRANCHED CHAIN ALKYLENE CONTAINING UP TO 4 CARBON ATOMS AND R2 IS STRAIGHT OR BRANCHED CHAIN, SATURATED OR UNSATURATED ALKYL OR CYCLOALKYL, AND SUCH GROUPS INTERRUPTED BY OXYGEN OR SULFUR ATOMS OR CONTAINING AN ENDO-ALKYLENE GROUP AND SUBSTITUTED OR UBSUBSTITUTED ARYL OR ARALKYL. THE AFORESAID SULFONYL UREAS CONSTITUTE EXTREMELY EFFECTIVE ANTI-DIABETIC AGENTS.

公开(公告)号：US3748319A

公开(公告)日：1973-07-24

申请号：US3748319D

申请日：1971-12-06

申请人： GULF OIL CORP

发明人： TOLLE G ,  MARHOFER E

IPC分类号： A23K1/00 ,  A23K1/16 ,  A23K1/22 ,  C07B21/00 ,  C07C127/00

CPC分类号： A23K50/15 ,  A23K20/158 ,  A23K40/30

摘要： THE PROCESS FOR MANUFACTURING INCLOSION COMPOUNDS OF UREA AND FATTY SUBSTANCES IN AN AQUEOUS MEDIUM IS IMPROVED BY USE OF A SLURRY INSTEAD OF A SOLUTION OF UREA AND PREFORMING ALL OF THE STEP AT AMBIENT TEMPERATURE SO AS TO IMPROVED THE SPEED OF REACTION AND REDUCE HEAT REQUIREMENTS.

公开(公告)号：US3723604A

公开(公告)日：1973-03-27

申请号：US3723604D

申请日：1971-03-03

申请人： GLANZSTOFF AG

发明人： RUPP H ,  MAGERLEIN H

IPC分类号： C01C3/20 ,  C07C127/00

CPC分类号： C01C3/20

摘要： Process for removing thiourea as an impurity from a crude alkali- or alkaline earth- metal rhodanide wherein an aqueous solution of the impure or crude rhodanide containing the thiourea is heated at certain elevated temperatures and in the presence of copper (II) oxide, preferably with an excess of the oxide with reference to a stoichiometric molar amount of the thiourea. Very pure rhodanides substantially free of thiourea are known to be useful in the manufacture of thiocyanates, especially organic thiocyanates, among other uses.

摘要翻译： 从粗碱金属或碱土金属的硫化铑中去除硫脲作为杂质的方法，其中含有硫脲的不纯或粗制的硫化铑的水溶液在一定升高的温度下加热，并在氧化铜（II）的存在下， 相对于硫脲的化学计量摩尔量的过量的氧化物。 已知非常纯的基本上不含硫脲的硫氰酸盐可用于制备硫氰酸盐，特别是有机硫氰酸盐，以及其它用途。

公开(公告)号：US3716350A

公开(公告)日：1973-02-13

申请号：US3716350D

申请日：1969-03-03

申请人： UNION OIL CO

发明人： HASHIMOTO S

IPC分类号： A01C15/00 ,  C05C9/00 ,  C07C127/00

CPC分类号： A01C15/00 ,  C05C9/00 ,  C05G3/0064

摘要： Urea is distributed onto the area to be fertilized by dropping particles of molten urea into the atmosphere 20-500 feet over the area such that the molten urea solidifies into small prills before contacting the area to be fertilized.

摘要翻译： 通过将熔融尿素颗粒滴落到该区域20-500英尺的空气中，将尿素分布到要受精的区域上，使得熔融的尿素在接触待受精的区域之前固化成小颗粒。

公开(公告)号：US3686305A

公开(公告)日：1972-08-22

申请号：US3686305D

申请日：1969-02-19

申请人： MITSUI TOATSU CHEMICALS

发明人： OTSUKA EIJI ,  KANAI KAZUMICHI ,  INOUE SHIGERU

IPC分类号： C07C273/04 ,  C07C127/00

CPC分类号： C07C273/04

摘要： A process for synthesizing urea comprising reacting carbon dioxide and ammonia at urea forming temperatures and pressures to produce a reaction mixture containing urea, water, unreacted ammonium carbamate, gaseous carbon dioxide and gaseous ammonia, introducing said reaction mixture into a heat recovering zone to recover excess heat of reaction thereby condensing most of said gaseous carbon dioxide and gaseous ammonia contained in reaction mixture, and further reacting the reaction mixture from said heat recovering zone to form additional urea.

摘要翻译： 一种用于合成尿素的方法，包括在尿素形成温度和压力下使二氧化碳和氨反应以产生含有尿素，水，未反应的氨基甲酸铵，气态二氧化碳和气态氨的反应混合物，将所述反应混合物引入热回收区以回收过量 反应热由此冷凝反应混合物中所含的大部分气态二氧化碳和气态氨，并进一步使来自所述热回收区的反应混合物反应形成额外的尿素。

公开(公告)号：US3682879A

公开(公告)日：1972-08-08

申请号：US3682879D

申请日：1969-08-29

申请人： DOW CHEMICAL CO

发明人： REIFSCHNEIDER WALTER

IPC分类号： C07D277/22 ,  C07D277/28 ,  C07C127/00

CPC分类号： C07D277/22 ,  C07D277/28

摘要： A UREA COMPOUND COMPLEX OF A COMPOUND WHICH IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF

(2-(4-((R")2-N-),(R''")2-PHENYL),3-R'',4,5-DI(R-)-

THIAZOLIUM)M (X(-))M

WHEREIN X REPRESENTS A PHARMACEUTICALLY-ACCEPTABLE ANION; R, EACH BEING TAKEN SEPARATELY, REPRESENTS HYDROGEN OR LOWERALKYL, OR BOTH R MOIETIES, TAKEN TOGETHER, REPRESENT STRAIGHT-CHAIN ALKYLENE BEING OF FROM 3 TO 6, BOTH INCLUSIVE, CARBON ATOMS; R'' REPRESENTS PRIMARY LOWERALKYL; EACH R" INDEPENDENTLY REPRESENTS HYDROGEN OR PRIMARY LOWERALKYL; EACH R''" INDEPENDENTLY REPRESENTS HYDROGEN BROMO, CHLORO, METHOXY, OR METHYL; AND M REPRESENTS AN INTEGER EQUAL TO THE VALENCE OF TEH ANION X. THE COMPLEXES ARE USEFUL AS AGENTS FOR REGULATING THE GROWTH OF PLANTS.

公开(公告)号：US3657339A

公开(公告)日：1972-04-18

申请号：US3657339D

申请日：1969-09-26

申请人： ALLIED CHEM

发明人： KUTSHER GEORGE S ,  ELLIOTT GEORGE A

IPC分类号： C07C273/02 ,  C07C127/00

CPC分类号： C07C273/02

摘要： AN IMPROVED SOLVENT AND PROCESS FOR MAKING UREA BY REACTION OF AMMONIA, SULFU AND CARBON MONOXIDE. THE PROCESS INVOLVE THE USE OF A REACTION SOLVENT COMPRISING A MIXUTRE OF DIALKYL ETHERS OF POLYALKYLENE GLYCOLS HAVING AN AVERAGE MOLECULAR WEIGHT BETWEEN ABOUT 2000 AND ABOUT 400. BY-PRODUCT HYDROGEN SULFIDE IS CONTINUOUSLY STRIPPED FROM THE REACTION MIXTURE WITH EXCESS CARBON MONOXIDE, ABSORBED IN SOLVENT RECOVERED FROM THE REACTION PRODUCT MIXTURE, AND OXIDIZED TO SULFUR WITH AN OXYGEN-CONTAINING GAS IN THE PRESENCE OF A CARBON CATALYST. THE RESULTING SULFUR-CONTAINING SOLVENT MIXTURE IS RECYCLIED TO THE UREA SYNTHESIS REACTION. THUS, ONLY CARBON MONOXIDE, AMMONIA

AND OXYGEN (AIR) ARE CONSUMED IN THE OVERALL PROCESS FOR PRODUCTION OF UREA.