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223 条记录 (耗时 0.034 秒)

    Scanning system and method for scanning a plurality of samples
    64.
    发明申请
    Scanning system and method for scanning a plurality of samples 有权

    公开(公告)号：US20030133108A1

    公开(公告)日：2003-07-17

    申请号：US10387755

    申请日：2003-03-13

    申请人： Applera Corporation

    发明人： Mark F. Oldham ,  Eugene F. Young

    IPC分类号： G01J003/30

    CPC分类号： G01N21/6452 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2300/0806 ,  B01L2300/0819

    摘要： A system for detecting fluorescence emitted from a plurality of samples in a sample tray is provided. The system generally includes a plurality of lenses positioned in a linear arrangement, a linear actuator configured to translate the plurality of lenses, an excitation light source for generating an excitation light, an excitation light direction mechanism for directing the excitation light to a single lens of the plurality of lenses at a time so that a single sample holder aligned with the lens is illuminated at a time, and an optical detection system for analyzing light from the sample holders. In certain embodiments, the optical detection system includes a light dispersing element configured to spectrally disperse the light from the sample holder being illuminated, and a lens element configured to receive light from the light dispersing element and direct the light onto a light detection device. A method of scanning a sample tray having a plurality of samples positioned in sample holders to detect fluorescence is also provided.

    Concentration and cleanup of nucleic acid samples
    68.
    发明申请
    Concentration and cleanup of nucleic acid samples 有权
    核酸样品的浓缩和清除

    公开(公告)号：US20030070925A1

    公开(公告)日：2003-04-17

    申请号：US10237537

    申请日：2002-09-09

    申请人： APPLERA CORPORATION

    发明人： Karl O. Voss

    IPC分类号： G01N027/26 ,  G01N027/447

    CPC分类号： G01N27/44791 ,  B01L3/5027 ,  G01N27/44743 ,  G01N27/44756 ,  G01N2001/4038

    摘要： Methods and devices are described for concentration and cleanup of samples containing bio-molecule analytes (e.g., polynucleotides, such as DNA, RNA, PNA). Various embodiments provide for pH-mediated sample concentration and cleanup of nucleic acid samples with channel devices (e.g., cross-T format, microchannel devices).

    摘要翻译： 描述了用于浓缩和清除含有生物分子分析物（例如多核苷酸，例如DNA，RNA，PNA）的样品的方法和装置。 各种实施方案提供pH介导的样品浓度并用通道装置（例如，交叉T格式，微通道装置）清除核酸样品。