公开(公告)号：US07579184B2

公开(公告)日：2009-08-25

申请号：US11443531

申请日：2006-05-30

Applicant: Finny Mathew ,  David Olson ,  Zarini Muhammad-Tahir ,  John Cunningham

Inventor： Finny Mathew ,  David Olson ,  Zarini Muhammad-Tahir ,  John Cunningham

IPC: G01N33/553

CPC classification number: G01N27/3276 ,  Y10S436/806

Abstract: Conductimetric assay devices that have both low end and high end sensitivity are described. The geometric shape and/or arrangement of the capture zones make it possible for the assay devices to have both low end and high end sensitivity. Also described is a conductimetric assay device having a pre-capture zone to capture unbound analyte. The assay device overcomes the problem of flooding by the analyte.

Abstract translation: 描述了具有低端和高端灵敏度的电导测定装置。 捕获区域的几何形状和/或排列使测定装置具有低端和高端灵敏度成为可能。 还描述了具有捕获未结合的分析物的预捕获区的电导测定装置。 测定装置克服了被分析物淹没的问题。

公开(公告)号：US07501037B2

公开(公告)日：2009-03-10

申请号：US10882785

申请日：2004-07-01

Applicant: Jon Christopher Stroup ,  David Patrick Dailey ,  John Robert Walter ,  Thomas Scott Reich ,  Mark John Strocko ,  Randy Jon Clark ,  Brent David Olson

Inventor： Jon Christopher Stroup ,  David Patrick Dailey ,  John Robert Walter ,  Thomas Scott Reich ,  Mark John Strocko ,  Randy Jon Clark ,  Brent David Olson

IPC: B32B37/18 ,  B32B38/10

CPC classification number: E06B3/822 ,  Y10T156/1052 ,  Y10T156/108 ,  Y10T156/1093 ,  Y10T156/1744 ,  Y10T156/1751

Abstract: Disclosed are automated processes and systems for the assembly of composite doors, and doors made using such processes and systems. The automated process may comprise a continuous series of steps allowing individual doors to be made in tandem, rather than in batch. The process may allow for the automation of individual steps such that the need for coordinating separate assembly steps may be substantially reduced.

Abstract translation: 公开了用于组装复合门的自动化过程和系统，以及使用这些过程和系统制造的门。 自动化过程可以包括连续的一系列步骤，允许单独的门串联而不是批量制造。 该过程可以允许各个步骤的自动化，使得可以显着减少对协调分离的组装步骤的需要。

公开(公告)号：US20080228444A1

公开(公告)日：2008-09-18

申请号：US11466391

申请日：2006-08-22

Applicant: David Olson ,  Collin A. Rich ,  Clement James Goebel

Inventor： David Olson ,  Collin A. Rich ,  Clement James Goebel

IPC: G06F15/00

CPC classification number: G01N15/1429 ,  G01N35/00712 ,  G01N35/0092

Abstract: The flow cytometer user interface of the preferred embodiment comprises the steps of (1) running the sample and saving all collected data, (2) viewing the raw (or “unmodified”) data, (3) modifying the raw data (e.g., scaling and/or culling the raw data), (4) reviewing and saving the modified settings, and (5) exporting the saved data. Once the sample has been run and all collected data have been saved, the user can repeat the steps of modifying the raw data, saving the modified settings, and exporting the saved data as many times as necessary and/or desirable without the need to run an additional sample.

Abstract translation: 优选实施例的流式细胞仪用户界面包括以下步骤：（1）运行样本并保存所有收集的数据，（2）查看原始（或“未修改”）数据，（3）修改原始数据（例如缩放 和/或剔除原始数据），（4）查看和保存修改的设置，以及（5）导出保存的数据。 一旦样品运行并且所有收集的数据都被保存，用户可以重复修改原始数据，保存修改后的设置以及根据需要和/或需要导出保存的数据的步骤，而不需要运行 额外的样品。

公开(公告)号：US07408174B2

公开(公告)日：2008-08-05

申请号：US11078706

申请日：2005-03-14

Applicant: Wes From ,  Boyko Tchavdarov ,  Mike Marcu ,  Richard Gratton ,  David Olson ,  Jim Fraser ,  Dusko A. Kezele

Inventor： Wes From ,  Boyko Tchavdarov ,  Mike Marcu ,  Richard Gratton ,  David Olson ,  Jim Fraser ,  Dusko A. Kezele

IPC: B01D17/00

CPC classification number: C02F1/325 ,  A61L2/10 ,  C02F1/006 ,  C02F1/32 ,  C02F2201/3225 ,  C02F2201/3227 ,  C02F2201/3228 ,  C02F2201/324 ,  C02F2201/328

Abstract: The present invention relates to a fluid treatment system comprising: an inlet; an outlet; and a fluid treatment zone disposed between the inlet and the outlet. The fluid treatment zone has disposed therein: (i) an elongate first radiation source assembly having a first longitudinal axis, and (ii) an elongate second radiation source assembly having a second longitudinal axis. The first longitudinal axis and the second longitudinal axis are non-parallel to each other and to a direction of fluid flow through the fluid treatment zone. The present fluid treatment system has a number of advantages including: it can treat large volumes of fluid (e.g., wastewater, drinking water or the like); it requires a relatively small “footprint”; it results in a relatively lower coefficient of drag resulting in an improved hydraulic pressure loss/gradient over the length of the fluid treatment system; and it results in relatively lower (or no) forced oscillation of the radiation sources thereby obviating or mitigating of breakage of the radiation source and/or protective sleeve (if present). Other advantages are discussed in the specification.

Abstract translation: 本发明涉及一种流体处理系统，包括：入口; 一个出口 以及设置在入口和出口之间的流体处理区。 流体处理区已设置在其中：（i）具有第一纵向轴线的细长的第一辐射源组件，和（ii）具有第二纵向轴线的细长的第二辐射源组件。 第一纵向轴线和第二纵向轴线彼此不平行，并且流体流过流体处理区域的方向。 本流体处理系统具有许多优点，包括：它可以处理大量流体（例如，废水，饮用水等）; 它需要相对较小的“足迹”; 它导致相对较低的阻力系数导致在流体处理系统的长度上改善的液压损失/梯度; 并且其导致辐射源的相对较低（或不）强制振荡，从而消除或减轻辐射源和/或保护套筒（如果存在）的断裂。 其他优点在说明书中讨论。

公开(公告)号：US07397049B2

公开(公告)日：2008-07-08

申请号：US11386596

申请日：2006-03-22

Applicant: Raymond Callahan ,  David Olson ,  Wilhelm P. Platow ,  Stanislav S. Todorov

Inventor： Raymond Callahan ,  David Olson ,  Wilhelm P. Platow ,  Stanislav S. Todorov

IPC: G01N23/00 ,  G21K5/10

CPC classification number: H01J37/3171 ,  H01J2237/1501 ,  H01J2237/24405 ,  H01J2237/24507 ,  H01J2237/24542 ,  H01J2237/2487 ,  H01J2237/30472 ,  H01J2237/30477 ,  H01J2237/31705

Abstract: A system, method and program product for determining parallelism of an ion beam using a refraction method, are disclosed. One embodiment includes determining a first test position of the ion beam while not exposing the ion beam to an acceleration/deceleration electrical field, determining a second test position of the ion beam while exposing the ion beam to an acceleration/deceleration electrical field, and determining the parallelism of the ion beam based on the first test position and the second test position. The acceleration/deceleration electrical field acts to refract the ion beam between the two positions when the beam is not parallel, hence magnifying any non-parallelism. The amount of refraction, or lateral shift, can be used to determine the amount of non-parallelism of the ion beam. An ion implanter system and adjustments of the ion implanter system based on the parallelism determination are also disclosed.

Abstract translation: 公开了一种使用折射方法确定离子束的平行度的系统，方法和程序产品。 一个实施例包括确定离子束的第一测试位置，同时不将离子束暴露于加速/减速电场，确定离子束的第二测试位置，同时将离子束暴露于加速/减速电场，以及确定 基于第一测试位置和第二测试位置的离子束的平行度。 当光束不平行时，加速/减速电场用于折射两个位置之间的离子束，从而放大任何非平行度。 折射量或横向偏移可用于确定离子束的非平行度。 还公开了一种离子注入机系统和基于并行度测定的离子注入机系统的调整。

公开(公告)号：US20070213285A1

公开(公告)日：2007-09-13

申请号：US11233312

申请日：2005-09-22

Applicant: Gholamreza Sheikhnejad ,  Neal Goodwin ,  David Olson

Inventor： Gholamreza Sheikhnejad ,  Neal Goodwin ,  David Olson

IPC: A61K31/711 ,  C07H21/04

CPC classification number: A61K31/711

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract translation: 本发明涉及抑制基因表达的方法和组合物。 特别地，本发明提供了用于抑制参与癌症的癌基因的基于寡核苷酸的治疗剂。

公开(公告)号：US20070167720A1

公开(公告)日：2007-07-19

申请号：US11634826

申请日：2006-12-06

Applicant: Raju Viswanathan ,  Bevil Hogg ,  John Kinder ,  David Olson

Inventor： Raju Viswanathan ,  Bevil Hogg ,  John Kinder ,  David Olson

IPC: A61B5/05

CPC classification number: A61B90/08 ,  A61B34/70 ,  A61B34/73

Abstract: A method of exploiting a medical technology comprising: providing at least two types of medical systems incorporating the medical technology. Each of the systems has first capabilities useful in performing a first type of medical procedure, and second capabilities useful in performing a second type of medical procedure. One of the medical systems is offered in exchange for payment allowing access to both the first and second capabilities, and the other of the medical system is offered will full access to the first capabilities in exchange for payment, while access to the second capabilities are restricted and separately sold to the purchaser on an episodic basis.

Abstract translation: 一种开发医疗技术的方法，包括：提供结合医疗技术的至少两种类型的医疗系统。 每个系统具有用于执行第一类医疗程序的第一功能和用于执行第二类医疗程序的第二功能。 提供其中一个医疗系统以交换允许访问第一和第二功能的支付，并且提供的另一个医疗系统将完全访问第一能力以换取支付，而对第二能力的访问受到限制 并按照情节单独出售给买方。

公开(公告)号：US20070074871A1

公开(公告)日：2007-04-05

申请号：US11243263

申请日：2005-10-04

Applicant: David Olson ,  Bruce Proctor ,  Doug Berry ,  Kelly Phillips

Inventor： David Olson ,  Bruce Proctor ,  Doug Berry ,  Kelly Phillips

IPC: E21B43/00

CPC classification number: E21B43/121 ,  F04C2/107 ,  F04C13/008

Abstract: A progressing cavity pump (PCP) system that may be deployed in an existing well configuration without the need for a workover rig. A stator and tubing stop are first set in a conduit, such as production tubing, at a desired depth. In subsequent wireline runs, a pack-off and upper tubing stop are installed above the stator, which results in the stator assembly being set by tubing stops on top and bottom and results in the conduit above the PCP being isolated from the wellbore below. Installation of the system is completed by installing the rotor and by installing top-side drive equipment in the usual way. The PCP system allows the deployment of lift systems within existing well configurations without any element being deployed on tubing and provides the ability to retrofit a well with an insertable pump within existing tubing.

Abstract translation: 先进的腔泵（PCP）系统，可以部署在现有的井配置中，而不需要修井机。 首先将定子和管道止动件设置在诸如生产管道的导管中，以期望的深度。 在随后的有线运行中，在定子上方安装有一个包装和上部管道止动件，这导致定子组件由顶部和底部的管道止动件设置，并导致PCP上方的导管与下面的井眼隔离。 通过安装转子并以通常的方式安装顶侧驱动设备来完成系统的安装。 PCP系统允许将电梯系统部署在现有的井结构中，而不会在管道上部署任何元件，并提供使用现有管道内的可插入泵对井进行改造的能力。

公开(公告)号：US20060247737A1

公开(公告)日：2006-11-02

申请号：US11119361

申请日：2005-04-29

Applicant: David Olson ,  Andrew Schmeling ,  Steve Nelson

Inventor： David Olson ,  Andrew Schmeling ,  Steve Nelson

IPC: A61N1/378

CPC classification number: A61N1/3787 ,  A61N1/08

Abstract: System for transcutaneous energy transfer. An implantable medical device, adapted to be implanted in a patient, has componentry for providing a therapeutic output. The implantable medical device has an internal power source and a secondary coil operatively coupled to the internal power source. An external power source, having a primary coil, provides energy to the implantable medical device when the primary coil of the external power source is placed in proximity of the secondary coil of the implantable medical device and thereby generates a current in the internal power source. An alignment indicator reports the alignment as a function of the current generated in the internal power source with a predetermined value associated with an expected alignment between the primary coil and secondary coil.

公开(公告)号：US20060241734A1

公开(公告)日：2006-10-26

申请号：US11113867

申请日：2005-04-25

Applicant: Mark Marshall ,  Teresa Whitman ,  Suping Lyu ,  Elizabeth Nagy ,  David Olson

Inventor： Mark Marshall ,  Teresa Whitman ,  Suping Lyu ,  Elizabeth Nagy ,  David Olson

IPC: A61N1/05

CPC classification number: A61N1/0563 ,  Y10T29/49117

Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.