STIRRING-PROCESSING APPARATUS AND PROCESSING METHOD
    61.
    发明申请
    STIRRING-PROCESSING APPARATUS AND PROCESSING METHOD 有权
    搅拌加工设备和加工方法

    公开(公告)号:US20150328602A1

    公开(公告)日:2015-11-19

    申请号:US14655291

    申请日:2012-12-25

    Inventor: Masakazu ENOMURA

    Abstract: A stirring-processing apparatus and a processing method are provided to realize excellent processing of a fluid regardless of the properties of the fluid. The stirring-processing apparatus is provided with the stirring blade and the stirring chamber provided with the screen, wherein the apparatus performs, under a state in which the stirring chamber is disposed in a fluid to be processed, a process of applying a shear force to the fluid by a relative rotation between the screen and the stirring blade. The stirring chamber is provided with the suction opening to suck the fluid from outside to inside and the ejecting opening to eject the fluid from inside to outside; these openings being disposed above and below. The suppressing body to control a flow of the fluid is disposed between the suction opening and the ejecting opening. The suppressing body is, for example, in the form of a cylinder, and is interposed between the suction flow and the ejecting flow, thereby suppressing interference between the two flows.

    Abstract translation: 提供了一种搅拌处理装置和处理方法,以实现流体的优异加工,而与流体的性质无关。 搅拌处理装置设有搅拌叶片和设有筛网的搅拌室,其中该装置在将搅拌室设置在待处理流体中的状态下进行施加剪切力的过程 流体通过筛网和搅拌叶片之间的相对旋转。 搅拌室设有吸入口,从外向内吸入流体,喷射口将流体从内向外排出; 这些开口设置在上下。 控制流体流动的抑制体设置在吸入口和排出口之间。 抑制体例如是气缸的形式,并且被插入在吸入流和喷射流之间,从而抑制两个流之间的干扰。

    METHOD FOR PRODUCING METAL MICROPARTICLES
    62.
    发明申请
    METHOD FOR PRODUCING METAL MICROPARTICLES 有权
    生产金属微量元素的方法

    公开(公告)号:US20150283616A1

    公开(公告)日:2015-10-08

    申请号:US14411792

    申请日:2013-09-12

    Abstract: Provided is a method for producing metal microparticles in which the ratio of crystallite diameter to the particle diameter of the metal microparticles is controlled. At least two types of fluid to be processed are used, including a metal fluid in which a metal or a metal compound is dissolved in a solvent, and a reducing agent fluid which includes a reducing agent. Sulfate ions are included in one or both of the metal fluid and the reducing agent fluid. The fluid to be processed is mixed in a thin film fluid formed between at least two processing surfaces, at least one of which rotates relative to the other, and which are disposed facing each other and capable of approaching and separating from each other, and metal microparticles are precipitated. The present invention is characterized in that at this time, the ratio (d/D) of the crystallite diameter (d) of the metal microparticles to the particle diameter (D) of the metal microparticles is controlled by controlling the molar ratio of metal and sulfate ions in the mixed fluid to be processed.

    Abstract translation: 提供了控制微晶直径与金属微粒的粒径的比的金属微粒的制造方法。 使用至少两种待处理的流体,包括其中金属或金属化合物溶解在溶剂中的金属流体和包含还原剂的还原剂流体。 硫酸根离子包括在一种或两种金属流体和还原剂流体中。 要处理的流体在形成在至少两个处理表面之间的薄膜流体中混合,所述至少两个处理表面中的至少一个相对于彼此旋转并且彼此面对地设置并且能够彼此接近和分离,并且金属 微粒析出。 本发明的特征在于,金属微粒的微晶粒径(d)与金属微粒的粒径(D)之比(d / D)通过控制金属和 待处理的混合流体中的硫酸根离子。

    METHOD FOR PRODUCING NANOPARTICLES
    63.
    发明申请
    METHOD FOR PRODUCING NANOPARTICLES 审中-公开
    生产纳米颗粒的方法

    公开(公告)号:US20150110709A1

    公开(公告)日:2015-04-23

    申请号:US14519944

    申请日:2014-10-21

    Inventor: Masakazu ENOMURA

    Abstract: A method for producing a nanoparticle to separate a diketopyrrolopyrrole pigment includes separating an α-type diketopyrrolopyrrole pigment nanoparticle having high crystallinity by carrying out separation of the diketopyrrolopyrrole pigment and crystal type transformation to the α-type with substantially a single step. The α-type diketopyrrolopyrrole pigment nanoparticle is separated by mixing a diketopyrrolopyrrole pigment solution having the diketopyrrolopyrrole pigment dissolved in a solvent and an alcohol solvent containing an alcohol compound solvent in a thin film fluid formed between at least two processing surfaces 1 and 2 arranged to be opposite to each other so as to be able to approach to and separate from each other, at least one of which rotates relative to the other. An acidic substance is contained in at least any one of the diketopyrrolopyrrole pigment solution and the alcohol solvent at this moment.

    Abstract translation: 用于分离二酮吡咯并吡咯颜料的纳米粒子的制造方法包括通过以基本上一个步骤进行二酮吡咯并吡咯颜料的分离和结晶型转变成α型,分离具有高结晶度的α型二酮吡咯并吡咯颜料纳米粒子。 通过将形成在溶剂中的二酮吡咯并吡咯颜料的二酮吡咯并吡咯颜料溶液和含有醇化合物溶剂的醇溶剂混合在形成在至少两个处理用面1和2之间的薄膜流体中来分离α型二酮吡咯并吡咯颜料纳米颗粒 彼此相对,以便能够彼此接近和分离,其中至少一个相对于另一个旋转。 此时,在二酮吡咯并吡咯颜料溶液和醇溶剂中至少含有一种酸性物质。

    METHOD FOR PRODUCING MICROPARTICLES
    64.
    发明申请
    METHOD FOR PRODUCING MICROPARTICLES 有权
    生产微生物的方法

    公开(公告)号:US20150020647A1

    公开(公告)日:2015-01-22

    申请号:US14379997

    申请日:2013-02-20

    Abstract: The present invention addresses the problem of providing a method for producing microparticles. Composite microparticles are separated by mixing at least two kinds of fluids to be processed in a thin film fluid that is formed between approachable and separable opposing processing surfaces that relatively rotate, wherein the fluids to be processed are a metal fluid comprising at least two kinds of metal elements that are dissolved in a solvent in the form of metal and/or metal compound and a fluid for separation containing at least one kind of separating substance for separating a composite substance comprising the at least two kinds of metal elements. The molar ratio between the at least two kinds of metal elements contained in the resulting microparticles is controlled by controlling the circumferential speed of the rotation at a confluence where the metal fluid and the fluid for separation merge at this time.

    Abstract translation: 本发明解决提供微粒生产方法的问题。 通过在相对旋转的可接近和可分离的相对的处理表面之间形成的薄膜流体中混合至少两种要处理的流体来分离复合微粒,其中待处理的流体是包含至少两种 溶解在金属和/或金属化合物形式的溶剂中的金属元素和含有至少一种用于分离包含至少两种金属元素的复合材料的分离物质的分离用流体。 所得微粒中所含的至少两种金属元素之间的摩尔比通过控制此时金属流体和分离流体合流的汇合处的旋转圆周速度来控制。

    SOLID METAL ALLOY
    65.
    发明申请
    SOLID METAL ALLOY 有权
    固体金属合金

    公开(公告)号:US20140308158A1

    公开(公告)日:2014-10-16

    申请号:US14358689

    申请日:2012-11-16

    Abstract: The present invention addresses the problem of providing a novel, sold metal alloy. Provided is a metal alloy containing two or more types of metal, wherein an equilibrium diagram of the metal alloy shows the two or more types of metal in a finely mixed state at the nanolevel in a specific region where the two types of metal are unevenly distributed. This metal alloy has a substitutional solid solution of the two or more types of metal as the principal constituent thereof. This metal alloy is preferably one obtained by precipitation after mixing ions of two or more types of metal and a reducing agent in a thin-film fluid formed between processing surfaces, at least one of which rotates relative to the other, which are arranged so as to face one another and are capable of approaching and separating from one another.

    Abstract translation: 本发明解决了提供一种新型销售的金属合金的问题。 提供了含有两种以上金属的金属合金,其中金属合金的平衡图在两种类型的金属不均匀分布的特定区域中显示纳米级的微细混合状态的两种或更多种金属 。 该金属合金具有作为其主要成分的两种以上的金属的取代固溶体。 这种金属合金优选是在将两种或更多种类型的金属和还原剂的离子混合在形成于其中的至少一个的处理表面之间形成的薄膜流体中的沉淀获得的,其中至少一个相对于另一个旋转, 彼此面对,有能力相互接近和分离。

    FLUID PROCESSING APPARATUS AND PROCESSING METHOD
    66.
    发明申请
    FLUID PROCESSING APPARATUS AND PROCESSING METHOD 审中-公开
    流体加工设备和加工方法

    公开(公告)号:US20140134068A1

    公开(公告)日:2014-05-15

    申请号:US14161171

    申请日:2014-01-22

    Inventor: Masakazu ENOMURA

    Abstract: A fluid is processed between processing surfaces capable of approaching to and separating from each other, at least one of which rotates relative to the other. A first fluid is introduced between processing surfaces, by using a micropump effect acting with a depression arranged on the processing surfaces from the center of the rotating processing surfaces. A second fluid, independent of this introduced fluid, is introduced from another fluid path that is provided with an opening leading to the processing surfaces, whereby the processing is done by mixing and stirring between the processing members.

    Abstract translation: 在能够接近和分离的处理表面之间处理流体,其中至少一个相对于另一个旋转。 通过使用与从旋转处理用面的中心配置在处理用面上的凹部起作用的微型泵效应,在处理用面之间引入第一流体。 独立于该引入的流体的第二流体从另一个流体路径引入,该流体路径设置有通向处理表面的开口,由此通过在处理构件之间混合和搅拌来进行处理。

    Heat exchanger
    67.
    发明授权

    公开(公告)号:US12235049B2

    公开(公告)日:2025-02-25

    申请号:US17783111

    申请日:2019-12-20

    Inventor: Masakazu Enomura

    Abstract: A heat exchanger with which a fluid to be treated or a generated gas can be prevented from stagnating in a heat transfer part, which can be disassembled for good washability, and which can be coated or lined. The heat exchanger is provided with tow flow passages, i.e. a first flow passage and a second flow passage, within a space formed between an inner tube and an outer tube which are concentric to each other. A spiral heat transfer body is disposed between the inner tube and the outer tube, and the spiral heat transfer body has a cross-sectional shape that is substantially triangular in the axial-direction cross section. The space is partitioned into the first flow passage and the second flow passage by the spiral heat transfer body, and heat is exchanged via the spiral heat transfer body between a first fluid flowing within the first flow passage and a fluid flowing within the second flow passage.

    BIOLOGICALLY ACTIVE SUBSTANCE UNIFORMLY DISPERSED MICROSPHERE AND A SUSTAINED RELEASE FORMULATION COMPRISING THE SAME

    公开(公告)号:US20230346706A1

    公开(公告)日:2023-11-02

    申请号:US18349753

    申请日:2023-07-10

    Inventor: Masakazu ENOMURA

    CPC classification number: A61K9/1647 A61K45/06

    Abstract: The present application provides a microsphere comprising a lactic acid-glycolic acid copolymer (PLGA) as a main component, in which a biologically active substance is uniformly dispersed, wherein an average volume-based particle diameter of the microsphere is 1 μm or more and 150 μm or less, and a mass of the biologically active substance or an empty hole of 1.5 μm or more is not present in the microsphere. The microsphere of the present invention can appropriately control the initial release amount of the biologically active substance and its release rate during a subsequent release period, and can continuously release the biologically active substance in vivo for a predetermined period of time.

    Forced thin film-type flow reactor and method for operating same

    公开(公告)号:US11583823B2

    公开(公告)日:2023-02-21

    申请号:US16616821

    申请日:2017-05-30

    Inventor: Masakazu Enomura

    Abstract: A forced thin film-type flow reactor is provided with a clearance adjustment mechanism that allows the clearance to be set and adjusted by an alternative means. The flow reactor processes a fluid to be processed by passing the fluid to be processed between a first processing surface and a second processing surface capable of moving towards and away from each other, and the flow reactor comprises a pressure balancing mechanism and a mechanical clearance mechanism. The pressure balancing mechanism forms a minute first clearance by providing pressure balance between the pressure applied by the fluid to be processed, which acts in the direction in which the first processing surface and the second processing surface move away from each other, and a force produced by a back pressure mechanism, which acts in the direction in which the first processing surface and the second processing surface move towards each other.

    FLOW REACTOR
    70.
    发明申请

    公开(公告)号:US20230022084A1

    公开(公告)日:2023-01-26

    申请号:US17789096

    申请日:2019-12-26

    Inventor: Masakazu ENOMURA

    Abstract: A flow reactor is structured to increase the overall heat transfer coefficient, which represents the efficiency of heat exchange with respect to a reactive fluid to be treated. This flow reactor is provided with three flow passages, which are a first flow passage, a second flow passage, and a third flow passage which spirally circulate within a space formed between an inner tube and an outer tube. The flow passages are compartmented by an inner heat transfer body and an outer heat transfer bodies. The heat transfer bodies spirally circulate, have a screw-like cross-sectional shape in an axial cross-sectional view, and are assembled in a screw-like configuration. By changing the shapes of a male-thread portion and a female-thread portion, the flow passage area of the first flow passage is changed, the second flow passage and the third flow passage are spirally formed, and heat exchange and reaction take place through the heat transfer bodies.

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