公开(公告)号：US06659949B1

公开(公告)日：2003-12-09

申请号：US09650431

申请日：2000-08-28

Applicant: Philipp Lang ,  John D. Mendlein

Inventor： Philipp Lang ,  John D. Mendlein

IPC: A61B800

CPC classification number: A61B8/0858 ,  A61B8/4236 ,  A61B8/4422 ,  A61B8/4472

Abstract: The present invention provides for methods and devices for monitoring capillary related interstitial thickness. The invention also includes methods of measuring capillary related interstitial fluid, as well as cardiac, vascular, renal and hepatic function. Specific devices, particularly probes, are provided for such methods.

Abstract translation: 本发明提供了用于监测毛细管相关间隙厚度的方法和装置。 本发明还包括测量毛细血管相关间质液以及心脏，血管，肾和肝功能的方法。 针对这些方法提供了具体的装置，特别是探针。

公开(公告)号：US06468505B1

公开(公告)日：2002-10-22

申请号：US09696352

申请日：2000-10-24

Applicant: Philipp Lang ,  Olivier Meyer ,  Michael F. Wendland ,  Maythem Saeed

Inventor： Philipp Lang ,  Olivier Meyer ,  Michael F. Wendland ,  Maythem Saeed

IPC: A61B5055

CPC classification number: A61K49/1812

Abstract: The present invention relates to the field of diagnostic imaging and more specifically to the field of monitoring drug delivery using non-invasive imaging techniques. The present invention provides for imaging agents and compositions useful for NMR, computed tomography, scintigraphy, PET and any other type of imaging where the imaging agent can be carried by liposomes or other lipid based vehicles, such as micelles or suspended lipid aggregates.

Abstract translation: 本发明涉及诊断成像领域，更具体地涉及使用非侵入性成像技术监测药物递送领域。 本发明提供用于NMR，计算机断层摄影，闪烁扫描，PET和任何其它类型成像的成像剂和组合物，其中成像剂可以由脂质体或其它基于脂质的载体如胶束或悬浮的脂质聚集体携带。

公开(公告)号：US06358208B1

公开(公告)日：2002-03-19

申请号：US09196507

申请日：1998-11-21

Applicant: Philipp Lang ,  John D. Mendlein

Inventor： Philipp Lang ,  John D. Mendlein

IPC: A61B800

CPC classification number: A61B8/0858 ,  A61B5/412 ,  A61B5/415 ,  A61B5/4869 ,  A61B8/06 ,  A61B8/4236 ,  A61B8/543

Abstract: The present invention provides for methods and devices for monitoring cardiovascular performance. The invention also includes methods of measuring capillary related interstitial fluid, as well as cardiac and vascular function. Specific devices, particularly probes, are provided for such methods.

Abstract translation: 本发明提供了用于监测心血管性能的方法和装置。 本发明还包括测量毛细血管相关间质液以及心脏和血管功能的方法。 针对这些方法提供了具体的装置，特别是探针。

公开(公告)号：US09877790B2

公开(公告)日：2018-01-30

申请号：US13294617

申请日：2011-11-11

Applicant: Raymond A. Bojarski ,  Nam T. Chao ,  John Slamin ,  Philipp Lang ,  Wolfgang Fitz ,  Daniel Steines

Inventor： Raymond A. Bojarski ,  Nam T. Chao ,  John Slamin ,  Philipp Lang ,  Wolfgang Fitz ,  Daniel Steines

IPC: A61F2/38 ,  A61B34/10 ,  A61F2/30 ,  A61F2/50 ,  A61B17/15 ,  B33Y80/00 ,  A61B17/17

CPC classification number: A61B34/10 ,  A61B17/155 ,  A61B17/157 ,  A61B17/1764 ,  A61B2034/107 ,  A61B2034/108 ,  A61F2/30942 ,  A61F2/384 ,  A61F2/3859 ,  A61F2/3886 ,  A61F2/389 ,  A61F2/5046 ,  A61F2002/30324 ,  A61F2002/30327 ,  A61F2002/30952 ,  A61F2002/3895 ,  B33Y80/00

Abstract: Methods and devices are disclosed relating improved articular models, implant components, and related guide tools and procedures. In addition, methods and devices are disclosed relating articular models, implant components, and/or related guide tools and procedures that include one or more features derived from patient-data, for example, images of the patient's joint. The data can be used to create a model for analyzing a patient's joint and to devise and evaluate a course of corrective action. The data also can be used to create patient-adapted implant components and related tools and procedures.

公开(公告)号：US09495483B2

公开(公告)日：2016-11-15

申请号：US13561696

申请日：2012-07-30

Applicant: Daniel Steines ,  Alexey Zhuravlev ,  John Slamin ,  Philipp Lang

Inventor： Daniel Steines ,  Alexey Zhuravlev ,  John Slamin ,  Philipp Lang

IPC: G06F17/50 ,  A61F2/30 ,  A61F2/38 ,  A61B17/16 ,  A61B17/00

CPC classification number: A61F2/30942 ,  A61B17/1662 ,  A61B17/1675 ,  A61B2017/00526 ,  A61B2034/108 ,  A61F2/38 ,  A61F2/3859 ,  A61F2002/30878 ,  A61F2002/30943 ,  A61F2002/30945 ,  A61F2002/30948 ,  A61F2002/30952 ,  A61F2002/3895 ,  G06F17/50

Abstract: Disclosed herein are devices, systems and methods for the automated design and manufacture of patient-specific/patient-matched orthopedic implants. While the embodiments described herein specifically pertain to unicompartmental resurfacing implants for the knee, the principles described are applicable to other types of knee implants (including, without limitation, other resurfacing implants and joint replacement implants) as well as implants for other joints and other patient-specific orthopedic applications.

Abstract translation: 本文公开了用于自动设计和制造患者特异性/患者匹配的整形外科植入物的装置，系统和方法。 虽然本文所述的实施例具体涉及用于膝盖的单室表面置换植入物，但是描述的原理适用于其他类型的膝盖植入物（包括但不限于其他表面置换植入物和关节置换植入物）以及其它关节和其他患者的植入物 特异性矫形应用。

公开(公告)号：US09451972B2

公开(公告)日：2016-09-27

申请号：US13306509

申请日：2011-11-29

Applicant: Philipp Lang ,  Wolfgang Fitz

Inventor： Philipp Lang ,  Wolfgang Fitz

IPC: G06F17/50 ,  A61B17/17 ,  A61B17/15 ,  A61B17/16 ,  A61F2/30 ,  A61F2/38 ,  A61B5/00 ,  A61B17/56

Abstract: Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.

公开(公告)号：US09408615B2

公开(公告)日：2016-08-09

申请号：US13013265

申请日：2011-01-25

Applicant: Wolfgang Fitz ,  Philipp Lang

Inventor： Wolfgang Fitz ,  Philipp Lang

IPC: A61B17/56 ,  A61B17/17 ,  A61B17/15 ,  A61B17/16 ,  A61F2/30 ,  A61F2/38 ,  G06F17/50 ,  A61B5/00

CPC classification number: A61B17/1739 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4523 ,  A61B5/4528 ,  A61B5/4533 ,  A61B17/15 ,  A61B17/154 ,  A61B17/155 ,  A61B17/157 ,  A61B17/158 ,  A61B17/1666 ,  A61B17/1675 ,  A61B17/1677 ,  A61B17/1682 ,  A61B17/1703 ,  A61B17/1746 ,  A61B17/1767 ,  A61B34/10 ,  A61B34/20 ,  A61B2017/568 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2/30756 ,  A61F2/30942 ,  A61F2/38 ,  B33Y80/00 ,  G06F17/50 ,  G06F19/00 ,  Y10T29/49

Abstract: Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.

公开(公告)号：US09358018B2

公开(公告)日：2016-06-07

申请号：US13405826

申请日：2012-02-27

Applicant: Wolfgang Fitz ,  Philipp Lang ,  Daniel Steines ,  Konstantinos Tsougarakis ,  Rene Vargas-Voracek

Inventor： Wolfgang Fitz ,  Philipp Lang ,  Daniel Steines ,  Konstantinos Tsougarakis ,  Rene Vargas-Voracek

IPC: B23Q17/00 ,  A61B17/17 ,  A61B17/15 ,  A61B17/16 ,  A61F2/30 ,  A61F2/46 ,  A61B5/00 ,  A61B17/70 ,  A61B17/88 ,  A61B19/00 ,  A61F2/36 ,  A61F2/38 ,  A61B6/00

CPC classification number: A61F2/30942 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4528 ,  A61B6/508 ,  A61B17/15 ,  A61B17/154 ,  A61B17/155 ,  A61B17/157 ,  A61B17/158 ,  A61B17/16 ,  A61B17/1666 ,  A61B17/1668 ,  A61B17/1671 ,  A61B17/1675 ,  A61B17/1739 ,  A61B17/1764 ,  A61B17/7098 ,  A61B17/8805 ,  A61B34/10 ,  A61B34/20 ,  A61B2034/102 ,  A61B2034/105 ,  A61B2034/108 ,  A61B2034/256 ,  A61B2090/061 ,  A61F2/30756 ,  A61F2/30767 ,  A61F2/30771 ,  A61F2/36 ,  A61F2/3859 ,  A61F2/4657 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2002/30787 ,  A61F2002/30841 ,  A61F2002/30894 ,  A61F2002/3092 ,  A61F2002/30948 ,  A61F2002/3095 ,  A61F2002/30957 ,  A61F2002/30962 ,  A61F2002/3097 ,  A61F2002/4631 ,  A61F2210/0004 ,  A61F2310/00011 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00047 ,  A61F2310/00065 ,  A61F2310/00071 ,  A61F2310/00077 ,  A61F2310/00083 ,  A61F2310/00107 ,  A61F2310/00113 ,  A61F2310/00119 ,  A61F2310/00131 ,  A61F2310/00143 ,  A61F2310/00149 ,  A61F2310/00155 ,  A61F2310/00293 ,  A61F2310/00383 ,  A61F2310/00395 ,  A61F2310/00592 ,  B23Q17/00 ,  B33Y70/00 ,  B33Y80/00 ,  Y10T29/49 ,  Y10T29/49764 ,  Y10T29/49778

Abstract: Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.

公开(公告)号：US09220517B2

公开(公告)日：2015-12-29

申请号：US13010299

申请日：2011-01-20

Applicant: Philipp Lang ,  Wolfgang Fitz

Inventor： Philipp Lang ,  Wolfgang Fitz

IPC: A61B17/56 ,  A61B17/17 ,  A61B17/15 ,  A61B17/16 ,  A61F2/30 ,  A61F2/38 ,  G06F17/50 ,  A61B5/00 ,  A61B19/00

CPC classification number: A61B17/1739 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4523 ,  A61B5/4528 ,  A61B5/4533 ,  A61B17/15 ,  A61B17/154 ,  A61B17/155 ,  A61B17/157 ,  A61B17/158 ,  A61B17/1666 ,  A61B17/1675 ,  A61B17/1677 ,  A61B17/1682 ,  A61B17/1703 ,  A61B17/1746 ,  A61B17/1767 ,  A61B34/10 ,  A61B34/20 ,  A61B2017/568 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2/30756 ,  A61F2/30942 ,  A61F2/38 ,  B33Y80/00 ,  G06F17/50 ,  G06F19/00 ,  Y10T29/49

Abstract: Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.

Abstract translation: 本文公开了用于修复关节表面修复材料和修复关节表面的方法，组合物和工具。 关节表面修复是可定制的或由患者高度可选择并且旨在提供最佳的适应和功能。 外科手术工具被设计成可由患者定制或高度可选择，以提高执行全部或部分关节置换术的速度，准确性和简单性。

公开(公告)号：US09107679B2

公开(公告)日：2015-08-18

申请号：US13305622

申请日：2011-11-28

Applicant: Philipp Lang ,  Wolfgang Fitz

Inventor： Philipp Lang ,  Wolfgang Fitz

IPC: A61B17/56 ,  A61B17/17 ,  A61B17/15 ,  A61B17/16 ,  A61F2/30 ,  A61F2/38 ,  G06F17/50 ,  A61B5/00 ,  A61B19/00

CPC classification number: A61B17/1739 ,  A61B5/4504 ,  A61B5/4514 ,  A61B5/4523 ,  A61B5/4528 ,  A61B5/4533 ,  A61B17/15 ,  A61B17/154 ,  A61B17/155 ,  A61B17/157 ,  A61B17/158 ,  A61B17/1666 ,  A61B17/1675 ,  A61B17/1677 ,  A61B17/1682 ,  A61B17/1703 ,  A61B17/1746 ,  A61B17/1767 ,  A61B34/10 ,  A61B34/20 ,  A61B2017/568 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2/30756 ,  A61F2/30942 ,  A61F2/38 ,  B33Y80/00 ,  G06F17/50 ,  G06F19/00 ,  Y10T29/49

Abstract: Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.