公开(公告)号：US20240316073A1

公开(公告)日：2024-09-26

申请号：US18574167

申请日：2022-07-07

Applicant: EPM (IP), Inc. ,  Yissum Res Dev Co of Hebrew Uni of Jerusalem Ltd.

Inventor： Reshef SWISA ,  Rotem SHER ,  Ron SHAHRABANI ,  Joseph TAM

IPC: A61K31/00 ,  A61P3/04 ,  A61P25/00

CPC classification number: A61K31/658 ,  A61K36/3482 ,  A61P3/04 ,  A61P25/00

Abstract: The present invention provides compositions and methods for treating Prader Willi Syndrome (PWS). In particular, the present invention provides pharmaceutical compositions and formulations comprising cannabidiolic acid (CBDA) ester derivatives alone or in combination with one or more additional cannabinoid compound(s), and a pharmaceutically acceptable carrier, excipient or diluent, for use in treating PWS.

公开(公告)号：US3915234A

公开(公告)日：1975-10-28

申请号：US50131074

申请日：1974-08-28

Applicant: CITIES SERVICE RES & DEV CO

Inventor： PELOFSKY ARNOLD H

IPC: E21B43/16 ,  E21B43/28 ,  E21B43/25

CPC classification number: E21B43/164 ,  E21B43/28

Abstract: Kerogen is recovered from oil shale deposits by introducing CO2 and H2S in water into the deposits under pressure and then shutting in the deposits to allow the H2S and CO2 solutions to dissolve the inorganic matrix material in the deposits. Kerogen is then recovered from the deposits, preferably as a colloidal suspension.

Abstract translation: 通过将CO 2和H 2 S在水中引入到压力下的沉积物中，然后关闭沉积物以使H 2 S和CO 2溶液溶解在沉积物中的无机基质材料，从油页岩沉积物中回收Kerogen。 然后从沉积物中回收Kerogen，优选作为胶体悬浮液。

公开(公告)号：US3902886A

公开(公告)日：1975-09-02

申请号：US16809371

申请日：1971-08-02

Applicant: YISSUM RES DEV CO

Inventor： BANIN AMOS

IPC: C05D9/00 ,  C05D9/02 ,  C05G3/04 ,  C07F5/06

CPC classification number: C04B33/06 ,  C04B33/30 ,  C05D9/00 ,  C05D9/02

Abstract: Cation-saturated clays such as iron-clay, zinc-clay, manganeseclay and copper-clay are utilized as a source of micronutrients for plants.

Abstract translation: 阳离子饱和的粘土如铁 - 粘土，锌 - 粘土，锰 - 粘土和铜 - 粘土被用作植物的微量营养元素的来源。

公开(公告)号：US3888761A

公开(公告)日：1975-06-10

申请号：US37179273

申请日：1973-06-20

Applicant: CITIES SERVICE RES & DEV CO

Inventor： STEWART NORMAN C

IPC: C10G45/20 ,  C10G47/28 ,  C10G1/08 ,  C10G13/00

CPC classification number: C10G45/20 ,  C10G47/28

Abstract: A process and apparatus are shown for the improved utilization of catalysts in a hydrocracking system. The method comprises passing a hydrocarbon oil feedstock, preferably a heavy hydrocarbon residuum, upwardly through a particulate catalyst bed in a reaction zone maintained at high temperature and high pressure, together with hydrogen-containing gas; recycling a portion of the upwardly flowing oil together with a portion of the particulate catalyst to the bottom of the reaction zone while simultaneously pulverizing the minor proportion of the particulate catalyst to a fine powdered catalyst; and passing the recycled oil and finely powdered catalyst upwardly through the particulate catalyst bed in the reaction zone, with at least a portion of the powdered catalyst leaving the reactor with the treated effluent. Apparatus for practicing this process comprises a reactor vessel having a vertically mounted recycle conduit mounted therein, and pulverizing means, preferably a modified axial turbine high-shear mixer communicatingly connected to the bottom of the recycle conduit, for pulverizing recycled particulate catalyst to a fine powdery catalyst. Additionally, a pump is mounted to the outlet of the high-shear turbine mixer to provide positive fluid flow.

公开(公告)号：US3835523A

公开(公告)日：1974-09-17

申请号：US33842573

申请日：1973-03-06

Applicant: P & O RES & DEV CO LTD

Inventor： STANSFIELD F

IPC: B66F3/30 ,  B25B29/02 ,  F16B31/04 ,  F16J1/00 ,  F16J1/09 ,  F16J15/32 ,  B23P11/02

CPC classification number: F16J1/09 ,  B25B29/02 ,  F16J15/32 ,  Y10S411/01 ,  Y10S411/916 ,  Y10T29/49874 ,  Y10T29/5383

Abstract: A self-straining bolt includes a shank and a rod of steel or like stiff rigid material which fits with clearance in an axial bore within the shank of the bolt, the bore being closed at one end. A closed cylindrical chamber is secured to the end of the bolt remote from the closed end of the bore, and a piston member which has an overall diameter greater than that of the bore, is fitted in the chamber. The piston member is a close sliding fit in the cylindrical chamber and engages the end of the rod adjacent the chamber. A disc of a resilient material with a hardness in the range of Shore hardness 10 to 100, and preferably 40 to 70, and a thickness of at least 3/8 inch, and preferably at least 1/2 inch, abut the working face of the piston and bears with its periphery against the cylindrical wall of the chamber so as to form a seal. A conduit extends through the wall of the chamber for connecting the chamber to a source of fluid under pressure whereby a pressure can be applied to the piston through the disc to cause the rod to press against the closed end of the bore and strain the shank of the bolt. The disc prevents fluid leaking from the chamber through the space between the piston and the cylindrical wall of the chamber.

Abstract translation: 自应变螺栓包括柄和杆或类似硬刚性材料的棒，该刚性材料与螺栓的柄部内的轴向孔中的间隙配合，孔在一端封闭。 闭合的圆柱形室被固定到远离孔的封闭端的螺栓的端部，并且具有大于孔的总直径的总直径的活塞构件安装在腔室中。 活塞构件在圆柱形腔室中紧密地滑动配合并且接合邻近腔室的杆的端部。 硬度在肖氏硬度10〜100，优选为40〜70，厚度为3/8英寸以上，优选为1/2英寸以上的硬度的弹性材料的盘， 活塞并且其周边承载在腔室的圆柱形壁上，以便形成密封。 导管延伸穿过室的壁，用于将腔室连接到压力源处，由此可以通过盘将活塞压力施加到活塞上，以使杆压靠孔的封闭端， 螺栓。 该盘防止流体从腔室泄漏通过活塞与腔室的圆柱形壁之间的空间。

公开(公告)号：US3749534A

公开(公告)日：1973-07-31

申请号：US3749534D

申请日：1970-12-21

Applicant: RES & DEV CO LTD

Inventor： MATTHEWS D

IPC: B29C47/88 ,  B29D7/20

CPC classification number: B29C47/885 ,  B29C47/0021

Abstract: An apparatus for producing sheets or films from mixtures of water and natural or synthetic rubber latex, and other gas having poor mechanical stability and therefore not susceptible of being directly pumped. A conveyor is arranged to receive the liquid mixture from a depositor having a linear outlet extending transversely of the conveyor. The conveyor is arranged to pass through a heating chamber after it has received the liquid mixture. The depositor is fed with liquid from a supply container, a supply conduit extending from the lower part of the container to the depositor. A displacement conduit extends between the upper part of the supply container and a displacement reservoir. The displacement gas reservoir is arranged to receive a supply of a displacement gas under pressure and a displacement liquid supply reservoir is arranged to supply displacement liquid to the displacement gas reservoir, to displace gas therefrom. Displacement liquid fed through the displacement conduit to the supply container forces liquid material from the supply container through the supply conduit to the depositor.

Abstract translation: 由水和天然或合成橡胶胶乳的混合物以及机械稳定性差的其他气体制造片材或膜的设备，因此不易直接泵送。 输送机布置成从具有沿输送机横向延伸的线性出口的储存器接收液体混合物。 输送机被布置成在接收到液体混合物之后通过加热室。 储存器从供应容器供应液体，供应管道从容器的下部延伸到储存器。 位移导管在供应容器的上部和位移容器之间延伸。 位移气体储存器被布置成在压力下接收位移气体的供应，并且位移液体供应储存器布置成将置换液体供应到置换气体储存器，以从其中移位气体。 通过位移导管供给到供应容器的置换液体迫使来自供应容器的液体材料通过供给管道到达沉积器。

公开(公告)号：US3710117A

公开(公告)日：1973-01-09

申请号：US3710117D

申请日：1970-04-27

Applicant: YISSUM RES DEV CO

Inventor： GROSS J ,  GORDON A

IPC: G01N33/78 ,  G21H5/00

CPC classification number: G01N33/78 ,  Y10S436/804

Abstract: Improved in vitro test method and apparatus for assessing thyroid function comprising mixing a microquantity of blood serum with a predetermined amount of a radioactive isotope tagged thyroid hormone solution in the upper portion of a tubular body having a fixed geometry, said body containing a column of predetermined quantity of cross linked dextran gel as a secondary binding site in an aqueous fluid held between porous discs in the lower portion of the body and having valve means at the lower end thereof, allowing said mixture to enter said column, determining the total added thyroid hormone by a radioactivity measurement, washing or eluting said column with a suitable fluid, determining the amount of hormone retained in said column by a radioactivity measurement and making a calculation based on the ratio of the amount of retained hormone to the total amount of added hormone for the particular thyroid hormone being assessed.

Abstract translation: 用于评估甲状腺功能的改进的体外试验方法和装置，包括将具有固定几何形状的管状体的上部中的血清微量量与预定量的放射性同位素标记的甲状腺激素溶液混合，所述体包含预定的柱 交联的葡聚糖凝胶的量作为在身体下部保持在多孔盘之间的水性流体中的二级结合位点，并且在其下端具有阀装置，允许所述混合物进入所述柱，确定总添加的甲状腺激素 通过放射性测量，用合适的流体洗涤或洗脱所述柱，通过放射性测量确定所述柱中保留的激素的量，并且基于保留的激素的量与加入的激素的总量的比例进行计算 正在评估特定的甲状腺激素。

公开(公告)号：US3635943A

公开(公告)日：1972-01-18

申请号：US3635943D

申请日：1969-10-16

Applicant: CITIES SERVICE RES & DEV CO

Inventor： STEWART NORMAN C

IPC: B01J8/22 ,  C10G49/12 ,  C10G13/02 ,  C10G23/00

CPC classification number: B01J8/22 ,  C10G49/12

Abstract: A PROCESS FOR TREATING HEAVY HYDROCARBON OIL WITH HYDROGEN GAS AT HIGH PRESSURES AND TEMPERATURES IN THE PRESENCE OF PARTICULATE CATALYSTS IS DISCLOSED HEREIN. THE PROCESS COMPRISES FEEDING THE HEAVEY HYDROCARBON OIL, PREFERABLY A VACUUM OR ATMOSPHERIC RESIDUUM, HYDROGEN GAS AND FINE PARTICULATE CATALYST IN THE SIZE RANGE OF UP TO ABOUT 600 MICRONS UPWARDLY THROUGH AN EXPANDED BED OF COARSE PARTICULATE CATALYST RANGING INSIZE FROM ABOUT 1/33 TO ABOUT 3/8 INCH AT A SUFFICIENT VELOCITY TO MAINTAIN THE BED IN AN EXPANDED, RANDOM MOTION STATE, REDUCING THE UPWARD VELOCITY OF THE HYDROCARBON OIL, HYDROGEN GAS AND FINE PARTICULATE CATALYST ABOVE THE EXPANDED COARSE CATALYST BED TO A VELOCITY SUFFICIENT TO ESTABLISH AN EXPANDED FINE CATALYST BED, AND WITHDRAWING THE TREATED HYDROCARBON OIL AND EFFLUENT GASES FROM THE HIGH PRESSURE, HIGH TEMPERATURE ZONE ABOVE THE FINE CATALYST BED.

公开(公告)号：US3621179A

公开(公告)日：1971-11-16

申请号：US3621179D

申请日：1970-02-16

Applicant: TETRONICS RES & DEV CO LTD

Inventor： TYLKO JOZEF K

IPC: B08B7/00 ,  C23G5/00 ,  B23K9/00

CPC classification number: C23G5/00 ,  B08B7/0035

Abstract: A method of treating a wearing surface of a railhead to remove an oil film and improve traction of a locomotive thereon in which effluent from a plasma jet torch is applied to the surface.

公开(公告)号：US3588592A

公开(公告)日：1971-06-28

申请号：US3588592D

申请日：1969-01-27

Applicant: YISSUM RES DEV CO

Inventor： BRANDSTADTER ISAAC JOSEPH

IPC: H05B41/04 ,  H05B41/02 ,  H05B41/16

CPC classification number: H05B41/046

Abstract: A STARTER FOR THE KIND OF FLUORESCENT LAMP WHICH IS USED IN A CIRCUIT ENERGIZED FROM AN AC SOURCE AND WHICH CAUSES A HIGH AC VOLTAGE ACROSS THE LAMP DURING STARTING AND A LOWER VOLTAGE ACROSS THE LAMP DURING LAMP OPERATION, THE STARTER BEING A SEMICONDUCTOR SWITCH WHICH DURING ALTERNATE HALF-CYCLES OF THE SUPPLY CAUSES HEATING OF THE FILAMENTS AND DURING THE OTHER HALF-CYCLES CAUSES THE FULL SUPPLY VOLTAGE TO BE APPLIED TO THE LAMP, THE HEATING OF THE LAMP FILAMENTS CEASING WHEN THE LAMP IS ENERGIZED AND THE LAMP VOLTAGE THEREBY FALLS.