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    Micro-cathode thruster and a method of increasing thrust output for a micro-cathode thruster
    67.
    发明授权
    Micro-cathode thruster and a method of increasing thrust output for a micro-cathode thruster 有权
    微阴极推进器和增加微型阴极推进器推力输出的方法

    公开(公告)号：US09517847B2

    公开(公告)日：2016-12-13

    申请号：US14503814

    申请日：2014-10-01

    申请人： The George Washington University

    发明人： Michael Keidar ,  Alexey Shashurin ,  Tai Sen Zhuang

    IPC分类号： B64G1/40 ,  F03H1/00 ,  H05H1/50

    CPC分类号： B64G1/405 ,  F03H1/0081 ,  F03H1/0087 ,  H05H1/50

    摘要： A magnetically enhanced micro-cathode thruster assembly provides long-lasting thrust. The micro-cathode thruster assembly includes a tubular housing, a tubular cathode, an insulator, an anode and a magnetic field. The tubular housing includes an open distal end. The tubular cathode is housed within the housing and includes a distal end positioned proximate the open distal end of the housing. The insulator is in contact with the cathode forming an external cathode-insulator interface. The anode is housed within the housing, proximate the open distal end of the housing. The magnetic field is positioned at or about the external cathode-insulator interface and has magnetic field lines with an incidence angle of about 20 to about 30 degrees and preferably about 30 degrees relative to the external cathode-insulator interface.

    摘要翻译： 磁力增强型微阴极推进器组件提供持久的推力。 微阴极推进器组件包括管状壳体，管状阴极，绝缘体，阳极和磁场。 管状壳体包括敞开的远端。 管状阴极容纳在壳体内并且包括靠近壳体的敞开的远端定位的远端。 绝缘体与阴极接触形成外部阴极 - 绝缘体界面。 阳极容纳在壳体内，靠近壳体的敞开的远端。 磁场定位在外部阴极 - 绝缘体界面处或周围，并且具有相对于外部阴极 - 绝缘体界面具有约20至约30度，优选约30度的入射角的磁场线。

    SYSTEM AND METHOD FOR PREDICTING TRANSFORMATIVE EVENTS IN MULTIVARIABLE SYSTEMS
    69.
    发明申请
    SYSTEM AND METHOD FOR PREDICTING TRANSFORMATIVE EVENTS IN MULTIVARIABLE SYSTEMS 审中-公开
    在多重系统中预测变形事件的系统和方法

    公开(公告)号：US20160283442A1

    公开(公告)日：2016-09-29

    申请号：US14668814

    申请日：2015-03-25

    申请人： The George Washington University a Congressionally Chartered Not-for-Profit Corporation

    发明人： Chenghang Du ,  Chen Zeng

    IPC分类号： G06F17/18 ,  G06F19/00

    CPC分类号： G06F17/18 ,  G16H50/20 ,  Y02A90/26

    摘要： A method of predicting a transformative event within a multivariable system includes receiving values for each of a plurality of variables of the multivariable system for a plurality of measurement times over a measurement time period; selecting a plurality of agitated variables as a sub-set of the plurality of variables; calculating a cross correlation coefficient between each pair of agitated variables from the plurality of agitated variables; identifying connected pairs of agitated variables based on the cross correlation coefficients; identifying all clusters of agitated variables such that each agitated variable within each cluster of agitated variables is a connected pair of agitated variables with at least one other agitated variable therein; identifying a percolating cluster of variables as the largest cluster of agitated variables from all clusters of agitated variables identified for the corresponding measurement time; receiving at least one nucleation core variable that is known to be associated with the transformative event; identifying all occurrences of the at least one nucleation core variable in each percolating cluster for each of the plurality of measurement times; calculating a nucleation index based on said all occurrences of the at least one nucleation core variable identified in each percolating cluster for each of the plurality of measurement times; comparing the nucleation index with a predetermined event index; and predicting the transformative event based on the comparing.

    摘要翻译： 一种预测多变量系统内的变换事件的方法包括在测量时间段内为多个测量时间接收多变量系统的多个变量中的每一个的值; 选择多个搅动变量作为所述多个变量的子集; 计算来自多个搅动变量的每对搅动变量之间的互相关系数; 基于互相关系数识别连接的搅动变量对; 识别搅动变量的所有簇，使得每个搅动变量簇内的每个搅动变量是连接的一对搅动变量，其中至少一个其它搅动变量; 将渗透的变量簇识别为在相应测量时间识别的所有搅动变量簇中的最大搅动变量簇; 接收已知与变换事件相关联的至少一个成核核心变量; 针对所述多个测量时间中的每一个识别每个渗滤簇中的所述至少一个成核核心变量的所有出现; 基于对于所述多个测量时间中的每一个在每个渗滤簇中识别的所述至少一个成核核心变量的所有出现计算成核指数; 将成核指数与预定事件指数进行比较; 并根据比较预测变革事件。

    ANGIOTENSIN II ALONE OR IN COMBINATION FOR THE TREATMENT OF HYPOTENSION
    70.
    发明申请
    ANGIOTENSIN II ALONE OR IN COMBINATION FOR THE TREATMENT OF HYPOTENSION 审中-公开
    ANGIOTENSIN II单独或组合用于治疗高血压

    公开(公告)号：US20160129072A1

    公开(公告)日：2016-05-12

    申请号：US14941301

    申请日：2015-11-13

    申请人： The George Washington University a Congressionally Chartered Not-for-Profit Corporation

    发明人： Lakhmir Chawla

    IPC分类号： A61K38/08 ,  A61K31/135 ,  A61K31/137

    CPC分类号： A61K38/085 ,  A61K9/0019 ,  A61K31/135 ,  A61K31/137

    摘要： The present invention relates, inter alia, to a method comprising administering to a subject having high output shock and undergoing treatment with a catecholamine at a dose equivalent to at least about 0.2 mcg/kg/min of norepinephrine a dose of angiotensin II which is effective to raise the blood pressure of the subject to a mean arterial pressure (MAP) of about 65 mm or above, and which is effective to reduce the dose of the catecholamine required to maintain a MAP of about 65 mm to the equivalent of about 0.05-0.2 mcg/kg/min norepinephrine or less, or to the equivalent of about 0.05 mcg/kg/min norepinephrine or less.

    摘要翻译： 本发明尤其涉及一种方法，其包括对具有高产出冲击的受试者施用相当于至少约0.2mcg / kg / min的去甲肾上腺素的剂量的血管紧张素II的有效量的儿茶酚胺进行治疗 将受试者的血压升高至约65mm或更高的平均动脉压（MAP），并且其有效地将维持约65mm的MAP所需的儿茶酚胺的剂量降低至约0.05- 去甲肾上腺素减少0.2 mcg / kg / min，或相当于约0.05 mcg / kg / min去甲肾上腺素或更少。