中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

231 records (took 0.023 seconds)

    Use Of Stearic Acid For Preventing Or Treating Pulmonary Fibrosis
    61.
    发明申请
    Use Of Stearic Acid For Preventing Or Treating Pulmonary Fibrosis 有权

    公开(公告)号：US20210205253A1

    公开(公告)日：2021-07-08

    申请号：US17059792

    申请日：2019-05-31

    Applicant: THE ASAN FOUNDATION ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION

    Inventor： Jin Woo SONG ,  Hyun Ju YOO ,  Jung Jin HWANG

    IPC: A61K31/20 ,  A61K9/00 ,  A61K31/7064 ,  A61K31/496 ,  A61K31/4418 ,  A61P11/00

    Abstract: The present invention relates to a composition for enhancing the sensitivity to a pulmonary fibrosis inhibitor, the composition comprising, as an active ingredient, stearic acid, a salt of the stearic acid or a prodrug of the stearic acid. In addition, the present invention relates to a pharmaceutical composition for preventing or treating pulmonary fibrosis, the composition comprising, as active ingredients: stearic acid, a salt of the stearic acid or a prodrug of the stearic acid; and a pulmonary fibrosis inhibitor. According to the present invention, a more excellent treatment effect may be induced by the co-administration of a conventional pulmonary fibrosis inhibitor and stearic acid, and by using stearic acid, the sensitivity to the conventional pulmonary fibrosis inhibitor may be enhanced, and an excellent treatment effect is expected to be achieved even for pulmonary fibrosis showing resistance to the conventional pulmonary fibrosis inhibitor.

    ESOPHAGEAL STETHOSCOPE
    62.
    发明申请
    ESOPHAGEAL STETHOSCOPE 有权

    公开(公告)号：US20210169439A1

    公开(公告)日：2021-06-10

    申请号：US17183145

    申请日：2021-02-23

    Applicant: THE ASAN FOUNDATION ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION

    Inventor： Sung Hoon KIM ,  Young Jin MOON

    IPC: A61B7/02 ,  A61B7/04 ,  A61B5/0205 ,  A61B5/00

    Abstract: An esophageal stethoscope is disclosed. The esophageal stethoscope includes a cuff, a tube, one end of which is disposed in the interior of the cuff, and extending to a side that is opposite to the one end thereof, a mount member mounted on an opposite end of the tube, and a microphone disposed in the interior of the mount member, the tube includes at least one hole configured to allow sound waves that passes through the cuff to be provided into the tube, and the microphone absorbs cardiac sound and converts the cardiac sound to a cardiac sound electric signal, and is electrically connected to an external device to deliver the cardiac sound electric signal to the external device.

    System and method for estimating acute cerebral infarction onset time
    63.
    发明授权
    System and method for estimating acute cerebral infarction onset time 有权

    公开(公告)号：US11026620B2

    公开(公告)日：2021-06-08

    申请号：US16417159

    申请日：2019-05-20

    Applicant: THE ASAN FOUNDATION ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION

    Inventor： Namkug Kim ,  Hyun Na Lee ,  Sung Won Ham ,  Dong Wha Kang

    IPC: G06K9/00 ,  A61B5/00 ,  G06T7/11 ,  G06T7/00 ,  G06T7/33 ,  A61B5/055

    Abstract: The present disclosure relates to a system and a method for estimating an acute cerebral infarction onset time. The method according to the present disclosure includes at least: receiving a first image and a second image of a first patient whose acute cerebral infarction onset time is not identified; extracting an infarction area image from the second image; aligning the second image with the first image; defining an infarction area in the first image, based on a result of the alignment of the second image with the first image; extracting feature information of the first patient, from the infarction area in the first image; comparing the extracted feature information with reference data; and calculating an amount of time that has elapsed since the acute cerebral infarction onset time, based on a result of the comparison of the extracted feature information with reference data.

    Biomarker for predicting sensitivity to EGFR-targeting agent, and use thereof
    64.
    发明授权
    Biomarker for predicting sensitivity to EGFR-targeting agent, and use thereof 有权

    公开(公告)号：US11008622B2

    公开(公告)日：2021-05-18

    申请号：US15329942

    申请日：2015-07-29

    Applicant: THE ASAN FOUNDATION

    Inventor： Tae Won Kim ,  Dong Hoon Jin ,  Seung Woo Hong ,  Jai Hee Moon ,  Jae Sik Shin ,  Seung Mi Kim ,  Dae Hee Lee ,  Eun Young Lee ,  Seul Lee ,  Yong Sang Hong

    IPC: C12Q1/6886 ,  C12Q1/68 ,  A61P43/00 ,  A61P35/00

    Abstract: The present disclosure relates to a new biomarker for predicting susceptibility to an EGFR-targeted agent and a use thereof, and more particularly, provides a biomarker for predicting susceptibility to an EGFR (Epidermal Growth Factor Receptor)-targeted agent, comprising a RON (Recepteur d'Origine Nantais) gene; a composition for predicting susceptibility to the EGFR-targeted agent, comprising an agent which measures a gene expression level of the biomarker; or an expression or activity level of a protein thereof; a composition for enhancing the susceptibility to the EGFR-targeted agent, comprising an inhibitor of the expression of the gene or the expression or activity of the protein of the gene as active ingredients; a kit for predicting the susceptibility to the EGFR-targeted agent, comprising the composition; and a method for predicting the susceptibility to the EGFR-targeted agent. According to the present disclosure, since an effect of predicting the susceptibility to the EGFR-targeted agent is excellent in a colon cancer, the present disclosure may be useful in the treatment of the colon cancer.

    METHOD FOR DETECTING MYCOPLASMA USING MITOCHONDRIAL DNA AS INTERNAL CONTROL SAMPLE
    65.
    发明申请
    METHOD FOR DETECTING MYCOPLASMA USING MITOCHONDRIAL DNA AS INTERNAL CONTROL SAMPLE 有权

    公开(公告)号：US20210115505A1

    公开(公告)日：2021-04-22

    申请号：US17055551

    申请日：2019-05-17

    Applicant: The Asan Foundation ,  University of Ulsan Foundation for Industry Cooperation

    Inventor： Eun Ju KANG ,  Yeon Mi LEE

    IPC: C12Q1/6851 ,  C12Q1/6888

    Abstract: The present invention provides a method for detecting mycoplasma, which can directly confirm whether a cell is infected with mycoplasma, by simultaneously amplifying DNA extracted from lysing a host cell infected with mycoplasma, and mitochondrial DNA in the cytoplasm of the host cell. According to the method of the present invention, by directly using the DNA inside the host cell, the DNA of mycoplasma bound around the nucleus of the host cell can be used as an amplification target, thereby increasing detection sensitivity. In addition, since the mitochondrial DNA inside the host cell is used as an amplification target of an internal control sample, whether the sample has been sampled in an appropriate amount can be confirmed in a convenient manner, and furthermore, by comparing the band size between the internal control sample and the mycoplasma DNA, the degree of mycoplasma infection can be quantitatively confirmed.

Patent Agency Ranking