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公开(公告)号:US11002735B2
公开(公告)日:2021-05-11
申请号:US16748001
申请日:2020-01-21
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Irun R. Cohen , Eytan Domany , Francisco Javier Quintana , Guy Hed , Gad Getz
IPC: G16B40/00 , G01N33/564 , G16B20/00 , G01N33/68
Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
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公开(公告)号:US10938486B2
公开(公告)日:2021-03-02
申请号:US16643862
申请日:2018-08-20
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Ulf Leonhardt
Abstract: An optical bus for multi-core processing providing optical data transfer between cores through a single planar waveguide employing a variable-thickness, light-propagation layer having a progressively changing effective refractive index in accordance with lateral position within the light-propagation layer such that light emission from a single light emitter in communication with one core is focused on each of multiple photodetectors in communication with its respective processer core.
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公开(公告)号:US10933124B2
公开(公告)日:2021-03-02
申请号:US15744881
申请日:2016-07-14
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Yair Reisner , Noga Or-Geva , Eran Ophir , Yaki Eidelstein , Rotem Gidron Budovsky
IPC: A61K35/17 , A61P31/00 , A61P35/04 , A61K39/00 , C12N5/078 , C12N5/0783 , A61K39/395 , C07K16/28 , A61K35/12
Abstract: A method of transplantation is disclosed. The method comprising administering to a subject in need of transplantation of cells in suspension, a therapeutically effective amount of anti-third party cells having a central memory T-lymphocyte (Tcm) phenotype, said anti-third party cells being tolerance-inducing cells and capable of homing to the lymph nodes following transplantation, wherein said cells in suspension comprise non-hematopoietic cells or hematopoietic cells which are not stem cells. Methods of treating and kits are also provided.
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公开(公告)号:US10933122B2
公开(公告)日:2021-03-02
申请号:US16521622
申请日:2019-07-25
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Irit Sagi , Eitan Wong , Ran Afik
Abstract: A method of treating an inflammatory disease is disclosed. The method comprises administering to the subject a therapeutically effective amount of a polypeptide comprising a pro-domain of TNF-alpha converting enzyme (TACE), said polypeptide being devoid of a catalytic domain of said TACE, said polypeptide comprising a modification at a site selected from the group consisting of R58, R56 and K57 which renders said polypeptide resistant to furin degradation said polypeptide being capable of downregulating an activity of TACE, thereby treating the inflammatory disease.
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公开(公告)号:US10923230B2
公开(公告)日:2021-02-16
申请号:US16412538
申请日:2019-05-15
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Eran Segal , Eran Elinav
Abstract: Method of predicting a response of a subject to food is disclosed. The method comprises: selecting a food to which a response of the subject is unknown; accessing a first database having data describing the subject but not a response of the subject to the selected food; accessing a second database having data pertaining to responses of other subjects to foods, the responses of the other subjects including responses of at least one other subject to the selected food or a food similar to said selected food; and analyzing the databases based on the selected food to estimate the response of the subject to the selected food.
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公开(公告)号:US10920192B2
公开(公告)日:2021-02-16
申请号:US14259997
申请日:2014-04-23
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Yaqub Hanna , Noa Novershtern , Yoach Rais
IPC: C12N5/0735 , C12N5/074
Abstract: Provided is an isolated human naive pluripotent stem cell (PSC), wherein: (i) when the naive PSC is a female PSC, then said naive female PSC has two unmethylated alleles of an X-inactive specific transcript (XIST) gene; and (ii) when said naive PSC is a male PSC, then said naive male PSC has an unmethylated allele of said XIST gene. Also provided is a culture medium which comprises an ERK1/2 inhibitor, a GSK3beta inhibitor, a p38 inhibitor, a JNK inhibitor, a STAT3 activator and at least one agent selected from the group consisting of: bFGF, TGFbeta 1, a PKC inhibitor, a ROCK inhibitor and a NOTCH inhibitor; or at least agent selected from the group consisting of: a TGFR inhibitor, a FGFR inhibitor, a PKC inhibitor, a ROCK inhibitor and a NOTCH inhibitor.
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公开(公告)号:US20200367493A1
公开(公告)日:2020-11-26
申请号:US16323787
申请日:2017-06-06
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Ilana KOLODKIN-GAL , Asaph AHARONI
Abstract: The present invention relates to the identification and use of natural plant compounds for inducing, enhancing and maintaining beneficial rhizobacteria biofilm formation on a plant or plant part thereof, and conversely, inhibiting formation of biofilms and pellicle by plant pathogens. Methods of use for stimulating matrix production from the beneficial rhizobacteria and enhanced adhesion of the rhizobacteria to a plant or plant part thereof are also described. Methods of use for inhibition plant pathogen adhesion to biofilms are also described.
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公开(公告)号:US20200338001A1
公开(公告)日:2020-10-29
申请号:US16809816
申请日:2020-03-05
Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD. , YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.
Inventor: Jacob Klein , Ronit Goldberg , Yechezkel Barenholtz , Avi Schroeder
Abstract: The invention provides a method for lubricating one or more surfaces, comprising applying gel-phase liposomes onto said one or more surfaces, wherein the temperature of said surface(s) at the time of lubrication is below the phase transition temperature Tm of said liposomes. The method can be used for lubricating non-biological surfaces, and also for lubricating the surfaces of a biological tissue in a mammalian subject, e.g., for treating joint dysfunction.
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公开(公告)号:US20200332391A1
公开(公告)日:2020-10-22
申请号:US16759751
申请日:2018-11-01
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Igor LUBOMIRSKY , Valery KAPLAN , Nurlan DOSMUKHAMEDOV , Erzhan ZHOLDASBAY
Abstract: A method for recovery of gold from gold-containing materials, such as electronic waste material, minerals and sands is described. The method includes crushing the gold containing material to obtain a particulate material. The particulate material is then preheated in an oxygen-containing gas environment in a preheating zone. The method also includes mixing the oxidized particulate material with a chlorine-containing material and treating the mixture in a reaction zone. The treatment is carried out by heating the mixture to provide thermal decomposition of the chlorine-containing material and produce a chlorine-containing gas mixture, and by applying an electromagnetic field to the chlorine-containing gas mixture to provide ionization of chlorine. A volatile gold-containing chloride product, produced in the reaction zone as a result of a chemical reaction between gold and chlorine ions, is then cooled to convert the volatile gold-containing chloride product into solid phase gold-containing materials.
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公开(公告)号:US20200300829A1
公开(公告)日:2020-09-24
申请号:US16894916
申请日:2020-06-08
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Noam SOBEL , Shani AGRON , Kobi SNITZ , Ethan LIVNE , Ofer PERL , Kineret WEISSLER , Aharon RAVIA , Danielle Ricca HONIGSTEIN , Maya FINKEL
IPC: G01N33/00
Abstract: A method of assessing odors, comprises providing an electronic nose that extracts measurements from odors, from which measurements at least n chemical descriptors are extracted where n is greater than unity, and typically around 18. The electronic nose is applied to an odor, and odor information is extracted. The information is plotted to a first location on an n-dimensional sample space, each dimension being related to a respective one of the n chemical descriptors or otherwise optimized for the particular enose and the measurements it makes; and an assessment of the odor is provided based on the plotted location. The assessment may be a description based on odor describing terms, or may be a chemical description in terms of chemicals that can synthesize the odor, and the odor may then be synthesized based on the chemical description.
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