公开(公告)号：US20210290384A1

公开(公告)日：2021-09-23

申请号：US17339316

申请日：2021-06-04

Applicant: Edwards Lifesciences Corporation

Inventor： Boaz Manash

IPC: A61F2/24

Abstract: In one embodiment, a prosthetic valve can comprise a radially expandable and compressible frame, which can include a plurality of struts which are pivotally joined together without requiring individual rivets. In some embodiments, the struts are interwoven, and can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In another embodiment, the frame comprises a plurality of inner struts and outer struts which are connected by a plurality of chains of interconnected rivets, avoiding the need to provide individual rivets at each junction between struts. In still another embodiment, separate hinges or flanged rivets are provided to interconnect the struts.

公开(公告)号：US11026785B2

公开(公告)日：2021-06-08

申请号：US16208263

申请日：2018-12-03

Applicant: Edwards Lifesciences Corporation

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir ,  Michael Bukin ,  Boaz Manash

IPC: A61F2/24 ,  A61F2/95

Abstract: In one embodiment, a prosthetic valve can comprise a radially expandable and compressible frame, which can include a plurality of struts which are pivotally joined together without requiring individual rivets. In some embodiments, the struts are interwoven, and can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In another embodiment, the frame comprises a plurality of inner struts and outer struts which are connected by a plurality of chains of interconnected rivets, avoiding the need to provide individual rivets at each junction between struts. In still another embodiment, separate hinges or flanged rivets are provided to interconnect the struts.

公开(公告)号：US20200170798A1

公开(公告)日：2020-06-04

申请号：US16784957

申请日：2020-02-07

Applicant: Edwards Lifesciences Corporation

Inventor： Noa Axelrod Manela ,  Oren H. Wintner ,  Eran Goldberg ,  Dikla Kersh ,  Danny M. Garmahi ,  Dan Rottenberg ,  Boaz Manash

IPC: A61F2/24 ,  A61B8/08 ,  A61B17/04 ,  A61B8/12 ,  A61B8/00

Abstract: Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.

公开(公告)号：US20200060827A1

公开(公告)日：2020-02-27

申请号：US16669447

申请日：2019-10-30

Applicant: Edwards Lifesciences Corporation

Inventor： Arie Tylis ,  Nikolay Gurovich ,  Eran Goldberg ,  Boaz Manash ,  Dan Rottenberg ,  Hagar Adika ,  Tal Regev ,  Dikia Kersh ,  Danny M. Garmahi ,  Heman Altman ,  Amir Blumenfeld

IPC: A61F2/24 ,  A61B8/12 ,  A61B8/00 ,  A61B8/08 ,  A61B17/04

Abstract: An anchoring system and related methods are provided for treatment of dilated hearts and of functional valve regurgitation, the system comprising one or more self-expandable or manually expandable anchors and associated devices for fixating a valve splint within the heart. For example, a spade-shaped assembly may be configured to be deployed in a right ventricle of the heart and to stabilize a puncturing instrument to puncture the septum. Various puncturing instruments may also be part of the anchoring system, including one or more of a flexible needle having a multiplicity of slits disposed along the length of the needle, a trocar catheter with a retractable head, and a catheter needle having a blunt introducer to protect nearby tissue within the heart during advancing a guidewire. A cutter catheter and puncture location catheter may also be part of the system and be used during treatment.

公开(公告)号：US20180325665A1

公开(公告)日：2018-11-15

申请号：US15978459

申请日：2018-05-14

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Alexey M. Tsypenyuk ,  Elena Sherman ,  Dikla Kersh ,  Boaz Manash ,  Liron Tayeb ,  Ziv Yohanan ,  Alexander Barash ,  Yair A. Neumann ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0069

Abstract: A prosthetic heart valve includes an annular frame including a plurality of strut members that is radially collapsible and expandable. A leaflet structure is situated within the frame, and includes a plurality of leaflets having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form one or more commissures. A commissure support element is positioned at each of the commissures, and comprise a first member and a second member that are separable from each other and configured to receive leaflets therebetween. The first and second members are detached from the frame and spaced radially inwardly from the frame such that the members contact the leaflets radially inward from the frame and limit movement of the leaflets so that they articulate at a location that is spaced radially inwardly from the frame.

公开(公告)号：US20180263764A1

公开(公告)日：2018-09-20

申请号：US15984678

申请日：2018-05-21

Applicant: Edwards Lifesciences Corporation

Inventor： Boaz Manash ,  Yoav Rozen ,  Eitan Atias

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/24 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2220/0033 ,  A61F2230/0091 ,  A61F2250/0063

Abstract: Systems and methods usable in delivering a docking device to a native valve of a patient's heart. A distal region of a delivery catheter can be positioned in an atrium of the heart and a distal tip can be positioned at or near a commissure of the native valve. The docking device can be located within the delivery catheter. A pusher, such as a pusher wire or tube, of a pusher tool can be advanced distally through the delivery catheter, wherein the pusher can push the docking device along within the delivery catheter. The docking device can be connected to the pusher tool by a line, such as a suture. A member of the pusher tool can be rotatable to change the amount of the suture extending from the pusher tool.

公开(公告)号：US20180206982A1

公开(公告)日：2018-07-26

申请号：US15876053

申请日：2018-01-19

Applicant: Edwards Lifesciences Corporation

Inventor： Sara Haivatov ,  Khen Perlmutter ,  Darshin S. Patel ,  Boaz Manash ,  Ajay Chadha ,  Waina Michelle Chu ,  Chambory Chhe ,  Evan T. Schwartz ,  Sandip Vasant Pawar

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/0077 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/243 ,  A61F2002/0086 ,  A61F2210/0076

Abstract: A prosthetic heart valve includes a frame having a plurality of strut members, an inflow end, and an outflow end. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering has a first layer and a second layer, wherein the second layer has a plush surface. The first layer is folded over a circumferential edge portion of the second layer to form a protective portion that extends beyond the strut members in a direction along a longitudinal axis of the prosthetic heart valve.

公开(公告)号：US20180153689A1

公开(公告)日：2018-06-07

申请号：US15831197

申请日：2017-12-04

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Boaz Manash ,  Eyal Leiba ,  Ziv Yohanan ,  Yair A. Neumann ,  Anatoly Dvorsky ,  Jonathan Bar-Or ,  Oren Cohen ,  Ofir Witzman ,  Liron Tayeb ,  Elazar Levi Schwarcz ,  Noam Miller ,  Tomer Saar

IPC: A61F2/24

Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.

公开(公告)号：US20180049873A1

公开(公告)日：2018-02-22

申请号：US15680030

申请日：2017-08-17

Applicant: Edwards Lifesciences Corporation

Inventor： Boaz Manash ,  Oren Cohen ,  Noam Nir ,  Ilan Tamir ,  Eitan Atias ,  Ofir Witzman ,  Michal Aliza Ruchelsman

IPC: A61F2/24 ,  A61M25/01 ,  A61M25/00 ,  A61M25/09

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2439 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2220/0008 ,  A61M25/0029 ,  A61M25/0068 ,  A61M25/0138 ,  A61M25/0147 ,  A61M25/09 ,  A61M2025/0039 ,  A61M2025/015

Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The delivery system can include a number of advantageous steering and delivery features, in particular for the transseptal delivery approach.

公开(公告)号：US20170135818A1

公开(公告)日：2017-05-18

申请号：US15353666

申请日：2016-11-16

Applicant: Edwards Lifesciences Corporation

Inventor： Noa Axelrod ,  Oren Wintner ,  Eran Goldberg ,  Dikla Kersh ,  Danny Garnahi ,  Dan Rottenberg ,  Boaz Manash

IPC: A61F2/24 ,  A61B8/00 ,  A61B8/12

Abstract: Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.