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公开(公告)号:US11103345B2
公开(公告)日:2021-08-31
申请号:US16262188
申请日:2019-01-30
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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公开(公告)号:US11759317B2
公开(公告)日:2023-09-19
申请号:US17071641
申请日:2020-10-15
Applicant: Edwards Lifesciences Corporation
Inventor: Son V. Nguyen , Kevin D. Rupp , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24 , D03D3/02 , D03D25/00 , D03D15/283
CPC classification number: A61F2/2409 , D03D3/02 , D03D15/283 , D03D25/005 , A61F2/2418 , A61F2210/0019 , A61F2210/0071 , A61F2210/0076 , A61F2220/0075 , A61F2230/0069 , A61F2240/004 , A61F2250/006 , A61F2250/0069 , D10B2509/00
Abstract: A docking device includes a hollow cylindrical body portion having an internal surface and an outer surface. The hollow cylindrical body portion is formed of a three-dimensional (3D) woven fabric comprising a plurality of different types of fibers.
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公开(公告)号:US11666437B2
公开(公告)日:2023-06-06
申请号:US16818182
申请日:2020-03-13
Applicant: Edwards Lifesciences Corporation
Inventor: Arvin T. Chang , Sam Sok , Amanda Kristine Anderson White , Ajay Chadha
CPC classification number: A61F2/243 , A61F2/2436 , A61F2/2418 , A61F2/97 , A61F2002/9528
Abstract: A delivery cylinder for a prosthetic implant can include a first tubular portion and a second tubular portion. The second tubular portion has a plurality of strut members coupled to the first tubular portion that define a volume for containing the prosthetic implant in a radially compressed state. The strut members can include respective flex regions configured such that application of force to the strut members causes deformation of the flex regions and corresponding radially inward or outward movement of the strut members relative to a longitudinal axis of the delivery cylinder between an expanded configuration and a contracted configuration.
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公开(公告)号:US20180168804A1
公开(公告)日:2018-06-21
申请号:US15841046
申请日:2017-12-13
Applicant: Edwards Lifesciences Corporation
Inventor: Son V. Nguyen , Kevin D. Rupp , Ajay Chadha , Jeff Lindstrom
Abstract: A docking device for a bioprosthesis is disclosed that can change shape and recover after a deforming stress is removed, that adjusts to surrounding conditions to accommodate different complex anatomic geometries, and that mitigates leakage around the bioprosthesis. The docking device can include a 3D woven fabric forming an internal surface, an outer surface, and a thickness therebetween. A filler can be coupled to the outer surface. A method for making a docking device is also provided. The method includes weaving a 3D woven fabric by interlacing a shape memory material, a low-melt thermoplastic polymer or resin having a melting point, and a high-tenacity biocompatible material; and pressing and heating the 3D woven fabric over a shape-setting mold at temperatures greater than the melting point of the low-melt thermoplastic polymer or resin.
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公开(公告)号:US20240189098A1
公开(公告)日:2024-06-13
申请号:US18443128
申请日:2024-02-15
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Sara Tzadok , Khen Perlmutter , Darshin S. Patel , Boaz Manash , Ajay Chadha , Waina Michelle Chu , Chambory Chhe , Evan T. Schwartz , Sandip Vasant Pawar
CPC classification number: A61F2/2412 , A61F2/0077 , A61F2/2409 , A61F2/2418 , A61F2002/0086 , A61F2/243 , A61F2210/0076
Abstract: A prosthetic heart valve has a frame including a plurality of strut members, the frame being radially expandable and collapsible between a collapsed state and an expanded state, the frame having an inflow end and an outflow end and defining a longitudinal axis. A leaflet structure is situated at least partially within the frame. A covering is disposed around an exterior of the frame and includes a cushioning layer, a first strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the inflow end of the frame, and a second strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the outflow end of the frame. The cushioning layer includes texturized filaments that provide compressible volume and a plush surface to the cushioning layer when the frame is in the expanded state.
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公开(公告)号:US10779941B2
公开(公告)日:2020-09-22
申请号:US15451149
申请日:2017-03-06
Applicant: Edwards Lifesciences Corporation
Inventor: Arvin T. Chang , Sam Sok , Amanda K. Anderson , Ajay Chadha
Abstract: A delivery cylinder for a prosthetic implant can include a first tubular portion and a second tubular portion. The second tubular portion has a plurality of strut members coupled to the first tubular portion that define a volume for containing the prosthetic implant in a radially compressed state. The strut members can include respective flex regions configured such that application of force to the strut members causes deformation of the flex regions and corresponding radially inward or outward movement of the strut members relative to a longitudinal axis of the delivery cylinder between an expanded configuration and a contracted configuration.
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公开(公告)号:US20190159895A1
公开(公告)日:2019-05-30
申请号:US16262188
申请日:2019-01-30
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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公开(公告)号:US20170258584A1
公开(公告)日:2017-09-14
申请号:US15451149
申请日:2017-03-06
Applicant: Edwards Lifesciences Corporation
Inventor: Arvin T. Chang , Sam Sok , Amanda K. Anderson , Ajay Chadha
Abstract: A delivery cylinder for a prosthetic implant can include a first tubular portion and a second tubular portion. The second tubular portion has a plurality of strut members coupled to the first tubular portion that define a volume for containing the prosthetic implant in a radially compressed state. The strut members can include respective flex regions configured such that application of force to the strut members causes deformation of the flex regions and corresponding radially inward or outward movement of the strut members relative to a longitudinal axis of the delivery cylinder between an expanded configuration and a contracted configuration.
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公开(公告)号:US20150320556A1
公开(公告)日:2015-11-12
申请号:US14704861
申请日:2015-05-05
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2002/9522 , A61F2220/0025 , A61F2220/0075 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61F2250/0069 , Y10T29/49927
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
Abstract translation: 公开了径向可折叠和可扩张的假体心脏瓣膜的实施例。 假体瓣膜可包括环形框架,小叶,内裙部和外裙部。 外裙部可以固定到框架的流入端部分的外部,外裙部具有纵向松弛,当阀处于膨胀构型时在径向向外弯曲,并且当阀处于折叠构型时它处于平坦状态。 在一些实施例中,外裙部在阀的轴向方向上比阀的圆周方向更硬。 在另外的实施例中,外裙部包括自膨胀织物,其包括由形状记忆材料制成的纤维,该形状记忆材料具有设置成增强外裙部径向向外屈曲的形状记忆。 还公开了将这种阀压接成折叠或部分收缩的构造的方法。
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公开(公告)号:US11938021B2
公开(公告)日:2024-03-26
申请号:US17456337
申请日:2021-11-23
Applicant: Edwards Lifesciences Corporation
Inventor: Sara Tzadok , Khen Perlmutter , Darshin S. Patel , Boaz Manash , Ajay Chadha , Waina Michelle Chu , Chambory Chhe , Evan T. Schwartz , Sandip Vasant Pawar
CPC classification number: A61F2/2412 , A61F2/0077 , A61F2/2409 , A61F2/2418 , A61F2002/0086 , A61F2/243 , A61F2210/0076
Abstract: A prosthetic heart valve has a frame including a plurality of strut members, an inflow end, and an outflow end. A leaflet structure is situated at least partially within the frame, and a covering is disposed around an exterior of the frame. The covering includes a cushioning layer, and a first strip member folded over an inflow circumferential edge portion of the cushioning layer to form a first protective portion. A second strip member is folded over an outflow circumferential edge portion of the cushioning layer to form a second protective portion. The first strip member and the second strip member are spaced apart from each other along a longitudinal axis of the prosthetic heart valve.
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