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公开(公告)号：US20200170798A1
公开(公告)日：2020-06-04
申请号：US16784957
申请日：2020-02-07
发明人： Noa Axelrod Manela , Oren H. Wintner , Eran Goldberg , Dikla Kersh , Danny M. Garmahi , Dan Rottenberg , Boaz Manash
摘要： Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.
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公开(公告)号：US10195025B2
公开(公告)日：2019-02-05
申请号：US14704861
申请日：2015-05-05
发明人： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
摘要： Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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公开(公告)号：US20190159895A1
公开(公告)日：2019-05-30
申请号：US16262188
申请日：2019-01-30
发明人： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC分类号： A61F2/24
摘要： Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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公开(公告)号：US20150320556A1
公开(公告)日：2015-11-12
申请号：US14704861
申请日：2015-05-05
发明人： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2002/9522 , A61F2220/0025 , A61F2220/0075 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61F2250/0069 , Y10T29/49927
摘要： Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
摘要翻译： 公开了径向可折叠和可扩张的假体心脏瓣膜的实施例。 假体瓣膜可包括环形框架，小叶，内裙部和外裙部。 外裙部可以固定到框架的流入端部分的外部，外裙部具有纵向松弛，当阀处于膨胀构型时在径向向外弯曲，并且当阀处于折叠构型时它处于平坦状态。 在一些实施例中，外裙部在阀的轴向方向上比阀的圆周方向更硬。 在另外的实施例中，外裙部包括自膨胀织物，其包括由形状记忆材料制成的纤维，该形状记忆材料具有设置成增强外裙部径向向外屈曲的形状记忆。 还公开了将这种阀压接成折叠或部分收缩的构造的方法。
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公开(公告)号：US12102528B2
公开(公告)日：2024-10-01
申请号：US17460079
申请日：2021-08-27
发明人： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2/9522 , A61F2220/0025 , A61F2220/0075 , A61F2230/0019 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61F2250/0069 , Y10T29/49927
摘要： Embodiments of a radially collapsible and expandable prosthetic heart valve and method for crimping the prosthetic heart valve are disclosed. A method of radially compressing a prosthetic valve can include partially inserting the valve while in a radially expanded configuration into a crimping device comprising crimper jaws, wherein a portion of the valve comprising an outer skirt extends outside of the crimper jaws. The method can further include crimping the valve to a first partially collapsed configuration, further inserting the valve into the crimping device, such that the outer skirt is between the crimper jaws, and crimping the valve to a second partially collapsed configuration, wherein a diameter of the valve is smaller in the second partially collapsed configuration than in the first partially collapsed configuration.
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公开(公告)号：US20210386543A1
公开(公告)日：2021-12-16
申请号：US17460079
申请日：2021-08-27
发明人： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC分类号： A61F2/24
摘要： Embodiments of a radially collapsible and expandable prosthetic heart valve and method for crimping the prosthetic heart valve are disclosed. A method of radially compressing a prosthetic valve can include partially inserting the valve while in a radially expanded configuration into a crimping device comprising crimper jaws, wherein a portion of the valve comprising an outer skirt extends outside of the crimper jaws. The method can further include crimping the valve to a first partially collapsed configuration, further inserting the valve into the crimping device, such that the outer skirt is between the crimper jaws, and crimping the valve to a second partially collapsed configuration, wherein a diameter of the valve is smaller in the second partially collapsed configuration than in the first partially collapsed configuration.
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公开(公告)号：US11446146B2
公开(公告)日：2022-09-20
申请号：US16784957
申请日：2020-02-07
发明人： Noa Axelrod Manela , Oren H. Wintner , Eran Goldberg , Dikla Kersh , Danny M. Garmahi , Dan Rottenberg , Boaz Manash
摘要： Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.
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公开(公告)号：US11103345B2
公开(公告)日：2021-08-31
申请号：US16262188
申请日：2019-01-30
发明人： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
摘要： Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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