公开(公告)号：US20090131472A1

公开(公告)日：2009-05-21

申请号：US11990050

申请日：2006-08-08

申请人： Meng-Hsin Chen ,  James B. Doherty ,  Robert Tynebor ,  Swaminathan R. Natarajan ,  Zhen Li ,  Soumya P. Sahoo

发明人： Meng-Hsin Chen ,  James B. Doherty ,  Robert Tynebor ,  Swaminathan R. Natarajan ,  Zhen Li ,  Soumya P. Sahoo

IPC分类号： A61K31/4375 ,  C07D455/02 ,  A61P37/02

CPC分类号： C07D471/04

摘要： Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: (I) are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.

摘要翻译： 由化学式（I）或其药学上可接受的盐描述的化合物：（I）是p38的抑制剂，可用于治疗炎症，例如治疗类风湿性关节炎，类风湿性脊椎炎，骨关节炎，痛风性关节炎和其他关节炎病症 ; 发炎关节，湿疹，牛皮癣或其他炎症皮肤病如晒伤; 炎症性眼病，包括结膜炎; 皮肤炎，疼痛等与炎症有关的病症。

公开(公告)号：US07244854B2

公开(公告)日：2007-07-17

申请号：US11636156

申请日：2006-12-08

申请人： Chungu Xia ,  Zhonghua Tang ,  Jing Chen ,  Xinzhi Zhang ,  Zhen Li ,  Enxiu Guo

发明人： Chungu Xia ,  Zhonghua Tang ,  Jing Chen ,  Xinzhi Zhang ,  Zhen Li ,  Enxiu Guo

IPC分类号： C07D323/06 ,  C07D323/04

CPC分类号： C07D323/06

摘要： The present invention relates to a method of synthesizing trioxymethylene from formaldehyde by the catalytic action of an acidic ionic liquid. In the method, formaldehyde solution with a concentration of 30˜80 wt % is used as reactant, and an ionic liquid is used as catalyst. The cation moiety of the catalyst is selected from either imidazoles cation or pyridines cation, and the anion moiety of the catalyst is selected from one of p-tolyl benzene sulfonate, trifluoromethyl sulfonate, and hydrogen sulfate. In the present invention, ionic liquid is used, for the first time, as a catalyst to synthesize trioxymethylene from formaldehyde. The catalyst can be circularly used for continuous sampling.

摘要翻译： 本发明涉及一种通过酸性离子液体的催化作用从甲醛合成三甲基甲酰胺的方法。 在该方法中，使用浓度为30〜80重量％的甲醛溶液作为反应物，使用离子液体作为催化剂。 催化剂的阳离子部分选自咪唑阳离子或吡啶阳离子，催化剂的阴离子部分选自对甲苯基苯磺酸盐，三氟甲基磺酸盐和硫酸氢盐之一。 在本发明中，首次使用离子液体作为从甲醛合成三甲基甲酰胺的催化剂。 催化剂可循环用于连续取样。

公开(公告)号：US07099954B2

公开(公告)日：2006-08-29

申请号：US10186230

申请日：2002-06-27

申请人： Shipeng Li ,  Goubin Shen ,  Zhen Li

发明人： Shipeng Li ,  Goubin Shen ,  Zhen Li

IPC分类号： G06F15/16

CPC分类号： H04L47/283 ,  H04L47/10 ,  H04L47/193 ,  H04L47/36

摘要： Streaming media applications, e.g., sent over the Internet with TCP, can suffer from various fluctuations and low utilization due to TCP's Additive Increase Multiplicative Decrease (AIMD) congestion control mechanism. Improved methods and apparatuses are provided in which Logarithm-based Rate Control algorithms are employed to better utilize available bandwidth and/or control and smooth the sending rate of the streaming media.

摘要翻译： 流媒体应用程序，例如通过TCP发送的Internet，可能遭受各种波动和低利用率，这是由于TCP的加性增乘乘法减少（AIMD）拥塞控制机制。 提供了改进的方法和装置，其中采用基于对数的速率控制算法来更好地利用可用带宽和/或控制和平滑流媒体的发送速率。

公开(公告)号：US20050245575A1

公开(公告)日：2005-11-03

申请号：US10515192

申请日：2003-06-16

申请人： Weirong Chen ,  Jeffrey Hale ,  Zhen Li ,  Christopher Lynch ,  Sander Mills ,  William Neway

发明人： Weirong Chen ,  Jeffrey Hale ,  Zhen Li ,  Christopher Lynch ,  Sander Mills ,  William Neway

IPC分类号： A61K31/4245 ,  A61K31/454 ,  A61P1/02 ,  A61P1/04 ,  A61P1/16 ,  A61P1/18 ,  A61P3/10 ,  A61P7/06 ,  A61P9/10 ,  A61P11/00 ,  A61P11/02 ,  A61P11/06 ,  A61P13/12 ,  A61P17/00 ,  A61P17/06 ,  A61P17/14 ,  A61P19/02 ,  A61P21/00 ,  A61P21/04 ,  A61P25/00 ,  A61P25/06 ,  A61P25/28 ,  A61P27/02 ,  A61P27/12 ,  A61P29/00 ,  A61P31/00 ,  A61P31/04 ,  A61P31/12 ,  A61P31/18 ,  A61P35/00 ,  A61P35/02 ,  A61P37/02 ,  A61P37/06 ,  A61P37/08 ,  A61P43/00 ,  C07D413/02 ,  C07D413/10 ,  C07D413/14

CPC分类号： C07D413/10 ,  A61K31/4245 ,  C07D413/14

摘要： The present invention encompasses compounds of Formula I: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

摘要翻译： 本发明包括式I的化合物以及其药学上可接受的盐和水合物。 该化合物可用于治疗免疫介导的疾病和病症，例如骨髓，器官和组织移植排斥反应。 包括药物组合物和使用方法。

公开(公告)号：US10471253B2

公开(公告)日：2019-11-12

申请号：US15784073

申请日：2017-10-13

申请人： Zhen Li

发明人： Zhen Li

IPC分类号： A61N1/20 ,  A61N1/02 ,  A61N1/10 ,  A61H39/08

摘要： A system and method is provided for simulating a wellness promoting, DC variable electric field in an environment. A DC power source (DC input) and converter provide a DC output and generate an electric field in between positive and negative electrodes in an environment. An electric field detector measures and transmits information (data) about the strength of the actual electric field in the environment. A microprocessor receives the data and compares the information to the parameters of a wellness promoting electric field in order to direct the function of a pulse width modulator to modulate the DC output and thereby the DC variable electric field in real-time. The wellness of a subject in the environment of the DC variable electric field is enhanced by ensuring the positive electrode is proximal to a positive part of the subject and the negative electrode is proximal to a negative part of the subject.

公开(公告)号：US20190002924A1

公开(公告)日：2019-01-03

申请号：US15912385

申请日：2018-03-05

申请人： Defeng Xing ,  Najiaowa Yu ,  Wei Li ,  Zhen Li ,  Yang Yang

发明人： Defeng Xing ,  Najiaowa Yu ,  Wei Li ,  Zhen Li ,  Yang Yang

IPC分类号： C12P3/00 ,  C12N1/20 ,  C12R1/145 ,  C12R1/385 ,  C07H3/02 ,  C07H3/04 ,  C07C323/58

CPC分类号： C12P3/00 ,  C07C323/58 ,  C07H3/02 ,  C07H3/04 ,  C12N1/20 ,  C12R1/145 ,  C12R1/385

摘要： The present invention provides a method for fermentative hydrogen production under limited aerobic conditions by utilizing the respiratory interaction between a strictly anaerobic hydrogen producing bacterium, E. harbinense YUAN-3, and a facultative anaerobic bacterium, P. aeruginosa PAO1. The two bacteria are co-cultured to produce hydrogen gas in a culture medium without any anaerobic treatment. Sucrose, lactose or glucose are used as the carbon source for the co-culture which can promote the growth of E. harbinense YUAN-3 and reduce substrate competition between two bacteria. L-cysteine is added to increase the hydrogen yield and the production rate. Using 15 g/L glucose and 5 mmol/L L-cysteine, the invented method achieved the hydrogen production yield of 1.11 mol-hydrogen/mol-glucose.

公开(公告)号：US20180185637A1

公开(公告)日：2018-07-05

申请号：US15784073

申请日：2017-10-13

申请人： Zhen Li

发明人： Zhen Li

IPC分类号： A61N1/20 ,  A61N1/02

CPC分类号： A61N1/205 ,  A61H39/08 ,  A61N1/025 ,  A61N1/10

摘要： A system and method is provided for simulating a wellness promoting, DC variable electric field in an environment. A DC power source (DC input) and converter provide a DC output and generate an electric field in between positive and negative electrodes in an environment. An electric field detector measures and transmits information (data) about the strength of the actual electric field in the environment. A microprocessor receives the data and compares the information to the parameters of a wellness promoting electric field in order to direct the function of a pulse width modulator to modulate the DC output and thereby the DC variable electric field in real-time. The wellness of a subject in the environment of the DC variable electric field is enhanced by ensuring the positive electrode is proximal to a positive part of the subject and the negative electrode is proximal to a negative part of the subject.

公开(公告)号：US09645002B2

公开(公告)日：2017-05-09

申请号：US14226913

申请日：2014-03-27

申请人： Yibing Zhang ,  Limin Song ,  Mohsen Shahmirzadi Yeganeh ,  Geoff Keiser ,  Zhen Li ,  Michael G. Starkey

发明人： Yibing Zhang ,  Limin Song ,  Mohsen Shahmirzadi Yeganeh ,  Geoff Keiser ,  Zhen Li ,  Michael G. Starkey

IPC分类号： G01F23/24 ,  G01F23/292 ,  E21B47/04 ,  E21B47/06

CPC分类号： G01F23/246 ,  E21B47/042 ,  E21B47/06 ,  G01F23/2922

摘要： Systems and methods for identifying the level of media in a vessel with a sensing cable including an optical fiber sensor array aligned with a heating element disposed in the vessel. An excitation source is configured to propagate at least one heat pulse through the heating element along at least a portion of the sensing cable to affect an exchange of thermal energy between the heating element and the one or more media exposed to the sensing cable. An optical signal interrogator is adapted to receive a signal from each of a plurality of sensor locations and measure a temperature profile corresponding to the heat pulse at the sensor locations. A control unit is configured to identify a level of each of media by determining properties of the media exposed to the sensing cable at each of the sensor locations based on the temperature profile corresponding thereto.

公开(公告)号：US20160251816A1

公开(公告)日：2016-09-01

申请号：US14976833

申请日：2015-12-21

申请人： Zhen Li

发明人： Zhen Li

IPC分类号： E02B17/06 ,  E02B17/08 ,  E02B17/02

CPC分类号： E02B17/06 ,  B63B22/06 ,  B63B22/20 ,  B63C7/08 ,  E02B17/02 ,  E02B17/08

摘要： A subsea system for installing, suspending and removing underwater equipment below the surface of the sea is provided. The subsea system includes a landing base module for landing and positioning underwater equipment thereupon, the landing base module comprising a base member and a first buoyancy system; and a second buoyancy system for affixing to the underwater equipment, the second buoyancy system having sufficient buoyancy to float the underwater equipment toward the surface of the sea when detached from the landing base module, wherein the underwater equipment includes a ballast system structured and arranged to permit the underwater equipment to be lowered onto the landing base module. A method for installing, suspending and removing underwater equipment below the surface of the sea and a kit of parts are also provided.

摘要翻译： 提供了一种用于在海面以下安装，悬挂和拆除水下设备的海底系统。 海底系统包括用于着陆和定位水下设备的着陆基座模块，着陆基座模块包括基座构件和第一浮力系统; 以及用于固定在水下设备上的第二浮力系统，当与着陆基座模块分离时，第二浮力系统具有足够的浮力以使水下设备朝向海洋表面浮动，其中，水下设备包括一个构造和布置成 允许水下设备降落到着陆基座模块上。 还提供了一种用于在海面以下安装，悬挂和移除水下设备的部件的方法。

公开(公告)号：US09000315B2

公开(公告)日：2015-04-07

申请号：US13483767

申请日：2012-05-30

申请人： Matthew R. Baum ,  James P. Meagher ,  Zhen Li ,  Charles V. Edwards

发明人： Matthew R. Baum ,  James P. Meagher ,  Zhen Li ,  Charles V. Edwards

IPC分类号： H01H13/06 ,  H01H13/50 ,  H01H13/14 ,  H01H9/04 ,  H01H3/12 ,  H01H13/86

CPC分类号： H01H13/06 ,  H01H3/122 ,  H01H9/04 ,  H01H13/14 ,  H01H13/50 ,  H01H13/86 ,  H01H2009/048 ,  H01H2229/00

摘要： A manually operated switch assembly is disclosed. The switch assembly includes a housing, a switch mechanism, and an actuator assembly. The switch mechanism is housed within the housing and is configured to open or close a circuit upon actuation. The actuator assembly is shiftably supported by the housing and generally includes a depressible actuator and a stability element. The actuator presents an actuator length and serves to actuate the switch mechanism when depressed. The stability element is configured to ensure that the actuator moves substantially uniformly along the actuator length when the actuator is depressed such that actuation of the switch mechanism is facilitated regardless of where the actuator is depressed along the actuator length. The switch assembly may be waterproofed, and be formed, at least in part, by a curable liquid sealant supplied to the switch assembly from a single fluid source.

摘要翻译： 公开了一种手动开关组件。 开关组件包括壳体，开关机构和致动器组件。 开关机构容纳在壳体内并且被构造成在致动时打开或关闭电路。 致动器组件可由壳体可移动地支撑，并且通常包括可按压的致动器和稳定元件。 致动器呈现致动器长度并用于当按压时致动开关机构。 稳定元件构造成确保当致动器被按压时致动器沿着致动器长度基本均匀地移动，使得促动开关机构的致动而不管致动器沿着致动器长度被按压何处。 开关组件可以是防水的，并且至少部分地由从单个流体源供应到开关组件的可固化液体密封剂形成。