公开(公告)号：US08672936B2

公开(公告)日：2014-03-18

申请号：US11617364

申请日：2006-12-28

申请人： Chou Thao ,  Saurav Paul

发明人： Chou Thao ,  Saurav Paul

IPC分类号： A61B18/18

CPC分类号： A61B5/4848 ,  A61B18/14 ,  A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/0066 ,  A61B2018/00839 ,  A61B2018/143 ,  A61B2090/065

摘要： Systems and methods are disclosed for assessing tissue contact, e.g., for mapping tissue ablation or other procedures. An exemplary tissue contact sensing system comprises a flexible tip device. At least one piezoelectric sensor is housed within the flexible tip device. The at least one piezoelectric sensor is responsive to contact stress of the flexible tip device by generating electrical signals corresponding to the amount of contact stress. An output device is electrically connected to the at least one piezoelectric sensor. The output device receives the electrical signals for assessing tissue contact by the flexible tip device. Methods for assembling and using the flexible tip device are also disclosed.

摘要翻译： 公开了用于评估组织接触的系统和方法，例如用于映射组织消融或其它过程。 示例性组织接触感测系统包括柔性尖端装置。 至少一个压电传感器容纳在柔性尖端装置内。 至少一个压电传感器通过产生对应于接触应力量的电信号来响应柔性尖端装置的接触应力。 输出装置电连接到至少一个压电传感器。 输出装置接收用于评估柔性尖端装置的组织接触的电信号。 还公开了用于组装和使用柔性末端装置的方法。

公开(公告)号：US20080015568A1

公开(公告)日：2008-01-17

申请号：US11549100

申请日：2006-10-12

申请人： Saurav Paul ,  Chou Thao ,  Kedar Belhe ,  Reed Heimbecher

发明人： Saurav Paul ,  Chou Thao ,  Kedar Belhe ,  Reed Heimbecher

IPC分类号： A61B18/18

CPC分类号： A61B5/036 ,  A61B5/061 ,  A61B5/6885 ,  A61B18/1492 ,  A61B2018/00351 ,  A61B2090/065

摘要： An electrode catheter and a method for assessing catheter-tissue contact for tissue ablation are disclosed. An exemplary electrode catheter comprises a flexible catheter shaft. At least one piezoelectric sensor is oriented coaxial to the flexible catheter shaft. The at least one piezoelectric sensor is responsive to movement of the flexible catheter shaft by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one piezoelectric sensor. The output device receives the electrical signals for dynamically assessing a level of contact between the flexible catheter shaft and a moving tissue. In another exemplary embodiment, the system may be implemented in a hydrodynamic environment.

摘要翻译： 公开了电极导管和用于评估用于组织消融的导管 - 组织接触的方法。 示例性电极导管包括柔性导管轴。 至少一个压电传感器与柔性导管轴同轴地定向。 至少一个压电传感器通过产生对应于移动量的电信号来响应柔性导管轴的移动。 该系统还可以包括电连接到至少一个压电传感器的输出装置。 输出装置接收用于动态评估柔性导管轴和移动组织之间的接触程度的电信号。 在另一个示例性实施例中，系统可以在流体动力学环境中实现。

公开(公告)号：US20070123764A1

公开(公告)日：2007-05-31

申请号：US11617364

申请日：2006-12-28

申请人： Chou Thao ,  Saurav Paul

发明人： Chou Thao ,  Saurav Paul

IPC分类号： A61B5/04 ,  A61B18/14 ,  A61B5/103 ,  A61B5/117

CPC分类号： A61B5/4848 ,  A61B18/14 ,  A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/0066 ,  A61B2018/00839 ,  A61B2018/143 ,  A61B2090/065

摘要： Systems and methods are disclosed for assessing tissue contact, e.g., for mapping tissue ablation or other procedures. An exemplary tissue contact sensing system comprises a flexible tip device. At least one piezoelectric sensor is housed within the flexible tip device. The at least one piezoelectric sensor is responsive to contact stress of the flexible tip device by generating electrical signals corresponding to the amount of contact stress. An output device is electrically connected to the at least one piezoelectric sensor. The output device receives the electrical signals for assessing tissue contact by the flexible tip device. Methods for assembling and using the flexible tip device are also disclosed.

摘要翻译： 公开了用于评估组织接触的系统和方法，例如用于映射组织消融或其它过程。 示例性组织接触感测系统包括柔性尖端装置。 至少一个压电传感器容纳在柔性尖端装置内。 至少一个压电传感器通过产生对应于接触应力量的电信号来响应柔性尖端装置的接触应力。 输出装置电连接到至少一个压电传感器。 输出装置接收用于评估柔性尖端装置的组织接触的电信号。 还公开了用于组装和使用柔性末端装置的方法。

公开(公告)号：US10905494B2

公开(公告)日：2021-02-02

申请号：US13340127

申请日：2011-12-29

申请人： Saurav Paul ,  Riki Chou Thao

发明人： Saurav Paul ,  Riki Chou Thao

IPC分类号： A61B18/14 ,  A61B18/00 ,  A61B17/00 ,  A61B90/00

摘要： An ablation device for creating linear lesions comprises a flexible support structure defining at least a partial curve; and an electrode disposed on the flexible support structure. The electrode comprises a pressure sensitive conductive composite that is configured for electrical communication with an electrical conductor and a flexible conductive outer covering that covers at least a portion of the pressure sensitive conductive composite. Electrical resistance of the pressure sensitive conductive composite varies inversely in proportion to pressure that is applied to the pressure sensitive conductive composite. Methods of creating linear lesions are also provided.

公开(公告)号：US09855410B2

公开(公告)日：2018-01-02

申请号：US13143001

申请日：2009-12-30

申请人： Saurav Paul ,  Troy T. Tegg ,  Reed R. Heimbecher ,  Richard E. Stehr ,  Riki Chou Thao

发明人： Saurav Paul ,  Troy T. Tegg ,  Reed R. Heimbecher ,  Richard E. Stehr ,  Riki Chou Thao

IPC分类号： A61B6/00 ,  A61M39/10 ,  A61B5/00 ,  A61B18/14 ,  A61M25/00 ,  A61M25/01 ,  A61B5/06 ,  A61B5/107 ,  A61B18/24 ,  A61B17/00 ,  A61B90/00

CPC分类号： A61M39/10 ,  A61B5/0084 ,  A61B5/042 ,  A61B5/061 ,  A61B5/065 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6885 ,  A61B18/1492 ,  A61B18/24 ,  A61B2017/00057 ,  A61B2017/00084 ,  A61B2090/065 ,  A61M25/0043 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/007 ,  A61M25/0071 ,  A61M25/0074 ,  A61M25/01 ,  A61M25/0138 ,  A61M25/0141 ,  A61M2025/0002

摘要： A contact sensing assembly including a catheter and an electrode including a tip portion and a base portion, and a generally central axis, with the electrode being connected to a distal end of the catheter. Optical sensor(s) may be provided for emitting and/or receiving an optical signal, with a part of the optical signal being transverse to the central axis. Optical interference member(s) may be provided for interfering with the optical signal. A method for sensing contact force exerted by an electrode on a tissue includes directing an optical signal along a portion of a catheter, emitting and/or receiving an optical signal, with a part of the optical signal being at a predetermined angle relative to the central axis, and sensing changes in intensity of the optical signal based on displacement associated with the electrode tip portion based on the contact force exerted by the electrode on the tissue.

公开(公告)号：US09675410B2

公开(公告)日：2017-06-13

申请号：US11966576

申请日：2007-12-28

申请人： Saurav Paul ,  Troy T. Tegg ,  Chou Thao ,  Harry Puryear

发明人： Saurav Paul ,  Troy T. Tegg ,  Chou Thao ,  Harry Puryear

IPC分类号： A61B5/05 ,  A61B18/14 ,  A61B5/055 ,  A61B5/06 ,  A61B18/00 ,  A61B34/20 ,  A61B90/00

CPC分类号： A61B18/1492 ,  A61B5/055 ,  A61B5/06 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2034/2068 ,  A61B2090/374 ,  A61B2090/3954

摘要： An electrode for use on a medical device is disclosed. The electrode may have a main body of electrically conductive material extending along an axis and may have a proximal end and a distal end. The electrode may also include a magnetic resonance imaging (MRI) tracking coil disposed in the body. The MRI tracking coil may comprise electrically insulated wire. A catheter including an electrode, as well as a method for determining the location of an electrode, are also disclosed.

公开(公告)号：US08211102B2

公开(公告)日：2012-07-03

申请号：US11963321

申请日：2007-12-21

申请人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

发明人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

IPC分类号： A61B18/14

CPC分类号： G01L1/16 ,  A61B5/042 ,  A61B5/6885 ,  G01L5/0038 ,  Y10T29/49002

摘要： A contact sensing catheter system includes a catheter shaft having a distal end; a flexible conductive polymer electrode located at the distal end of the shaft; and an electro-mechanical contact sensor positioned at least partially within the electrode. The sensor outputs an electrical signal in response to a mechanical force acting thereon. The sensor may be a piezoelectric sensor, a strain gauge, a fiber optic sensor, or another suitable electro-mechanical contact sensor. The electrical signal output by the sensor typically varies in response to variations in the mechanical force acting on the sensor. An output device may receive the signal output by the contact sensor and present to a user of the system an indicator of contact between the electrode and a tissue by assessing, for example, the amplitude or periodicity of the signal.

摘要翻译： 接触感测导管系统包括具有远端的导管轴; 位于所述轴的远端的柔性导电聚合物电极; 以及至少部分地位于电极内的电 - 机械接触传感器。 传感器响应于作用在其上的机械力而输出电信号。 传感器可以是压电传感器，应变片，光纤传感器或另一适合的机电接触传感器。 由传感器输出的电信号通常响应于作用在传感器上的机械力的变化而变化。 输出装置可以接收由接触传感器输出的信号并且通过评估例如信号的幅度或周期性向系统的用户呈现电极和组织之间的接触的指示。

公开(公告)号：US20090158852A1

公开(公告)日：2009-06-25

申请号：US11963321

申请日：2007-12-21

申请人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

发明人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

IPC分类号： G01L9/00 ,  H01S4/00

CPC分类号： G01L1/16 ,  A61B5/042 ,  A61B5/6885 ,  G01L5/0038 ,  Y10T29/49002

摘要： A contact sensing catheter system includes a catheter shaft having a distal end; a flexible conductive polymer electrode located at the distal end of the shaft; and an electromechanical contact sensor positioned at least partially within the electrode. The sensor outputs an electrical signal in response to a mechanical force acting thereon. The sensor may be a piezoelectric sensor, a strain gauge, a fiber optic sensor, or another suitable electromechanical contact sensor. The electrical signal output by the sensor typically varies in response to variations in the mechanical force acting on the sensor. An output device may receive the signal output by the contact sensor and present to a user of the system an indicator of contact between the electrode and a tissue by assessing, for example, the amplitude or periodicity of the signal.

摘要翻译： 接触感测导管系统包括具有远端的导管轴; 位于所述轴的远端的柔性导电聚合物电极; 以及至少部分地位于电极内的机电接触传感器。 传感器响应于作用在其上的机械力而输出电信号。 传感器可以是压电传感器，应变计，光纤传感器或另一适合的机电接触传感器。 由传感器输出的电信号通常响应于作用在传感器上的机械力的变化而变化。 输出装置可以接收由接触传感器输出的信号，并通过评估例如信号的幅度或周期性向系统的用户呈现电极和组织之间的接触的指示。

公开(公告)号：US08226648B2

公开(公告)日：2012-07-24

申请号：US11968044

申请日：2007-12-31

申请人： Saurav Paul ,  Harry Puryear ,  Chou Thao

发明人： Saurav Paul ,  Harry Puryear ,  Chou Thao

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/1206 ,  A61B2018/00023 ,  A61B2018/00577 ,  A61B2018/00875

摘要： The present invention is directed to bipolar ablation systems. A bipolar electrode system for ablation therapy is disclosed, including a pressure-sensitive conducting composite layer and a pair of electrodes in electrical conductive contact or communication with the pressure-sensitive conducting composite layer. Energy (e.g., ablation energy) is delivered via the pressure-sensitive conductive composition when sufficient pressure is applied to transform the pressure-sensitive conductive composite to an electrical conductor. An electrically insulative flexible layer, which may include a passageway for a fill material is also disclosed. In some embodiments, the systems can also be used for targeted delivery of compounds, such as drugs, using a bipolar electrode.

摘要翻译： 本发明涉及双相消融系统。 公开了一种用于消融治疗的双极电极系统，包括压敏导电复合层和一对导电接触或与压敏导电复合层连通的电极。 当施加足够的压力以将压敏导电复合材料转变成电导体时，能量（例如，消融能量）经由压敏导电组合物递送。 还公开了可以包括用于填充材料的通道的电绝缘柔性层。 在一些实施方案中，所述系统也可用于使用双极电极靶向递送化合物，例如药物。

公开(公告)号：US20110022045A1

公开(公告)日：2011-01-27

申请号：US12893707

申请日：2010-09-29

申请人： Hong Cao ,  Riki Thao ,  Saurav Paul

发明人： Hong Cao ,  Riki Thao ,  Saurav Paul

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B5/6852 ,  A61B5/6885 ,  A61B2090/065

摘要： A catheter assembly for assessing contact between the catheter assembly and tissue is disclosed. In an exemplary embodiment the assembly includes a catheter shaft and a trio of pressure sensitive capacitive members each of whose electrical resistance varies with a pressure vector applied to the catheter assembly. The assembly also includes at least one measurement terminal to permit the measurement of changes in the electrical characteristics of the pressure sensitive capacitive members. The assembly may optionally include a measurement device to measure resistance, impedance and/or other electrical characteristics. The assembly may utilize a reference electrode secured to the patient's tissue, which permits the measurement device to measure changes between the reference electrode and the at least one measurement terminal. Optionally, the assembly may include a conductive outer layer. Also disclosed are sensor assemblies, contact sensor, methods of contact sensing, and methods of manufacturing relating to the use of pressure sensitive capacitors.

摘要翻译： 公开了一种用于评估导管组件和组织之间的接触的导管组件。 在示例性实施例中，组件包括导管轴和三个压敏电容构件，每个电阻构件的电阻随着施加到导管组件的压力矢量而变化。 组件还包括至少一个测量端子，以允许测量压敏电容构件的电特性的变化。 组件可以可选地包括测量电阻，阻抗和/或其他电特性的测量装置。 组件可以利用固定到患者组织的参考电极，其允许测量装置测量参考电极和至少一个测量终端之间的变化。 可选地，组件可以包括导电外层。 还公开了传感器组件，接触传感器，接触感测方法以及与使用压敏电容器有关的制造方法。