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    Systems and methods for electrode contact assessment
    1.
    发明授权
    Systems and methods for electrode contact assessment 有权
    电极接触评估的系统和方法

    公开(公告)号：US08162935B2

    公开(公告)日：2012-04-24

    申请号：US12091151

    申请日：2006-10-27

    申请人： Saurav Paul ,  Troy T. Tegg ,  Chou Thao ,  Hong Cao ,  Harry Puryear ,  Fos Kuehn ,  Reed R. Heimbecher

    发明人： Saurav Paul ,  Troy T. Tegg ,  Chou Thao ,  Hong Cao ,  Harry Puryear ,  Fos Kuehn ,  Reed R. Heimbecher

    IPC分类号： A61B18/14 ,  A61B5/04

    CPC分类号： A61B18/1492 ,  A61B5/6852 ,  A61B5/6885 ,  A61B2090/065

    摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode 10 housed within a distal portion of a catheter shaft 14. At least one electro-mechanical sensor 20 is operatively associated with the electrode 10 within the catheter shaft 14. The at least one electro-mechanical sensor 20 is responsive to movement of the electrode 10 by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electro-mechanical sensor 20. The output device receives the electrical signals for assessing a level of contact between the electrode 10 and a tissue 12.

    摘要翻译： 公开了用于评估用于组织消融的电极组织接触的系统和方法。 示例性的电极接触感测系统包括容纳在导管轴14的远端部分内的电极10.至少一个电 - 机械传感器20与导管轴14内的电极10可操作地相关联。至少一个电 - 机械传感器 20通过产生对应于移动量的电信号来响应于电极10的运动。 该系统还可以包括电连接到至少一个机电传感器20的输出装置。输出装置接收用于评估电极10和组织12之间的接触程度的电信号。

    Systems and Methods for Electrode Contact Assessment
    4.
    发明申请
    Systems and Methods for Electrode Contact Assessment 有权
    电极接触评估系统与方法

    公开(公告)号：US20080275442A1

    公开(公告)日：2008-11-06

    申请号：US12091151

    申请日：2006-10-27

    申请人： Saurav Paul ,  Troy T. Tegg ,  Chou Thao ,  Hong Cao ,  Harry Puryear ,  Fos Kuehn ,  Reed R. Heimbecher

    发明人： Saurav Paul ,  Troy T. Tegg ,  Chou Thao ,  Hong Cao ,  Harry Puryear ,  Fos Kuehn ,  Reed R. Heimbecher

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B5/6852 ,  A61B5/6885 ,  A61B2090/065

    摘要： Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode 10 housed within a distal portion of a catheter shaft 14. At least one electromechanical sensor 20 is operatively associated with the electrode 10 within the catheter shaft 14. The at least one electromechanical sensor 20 is responsive to movement of the electrode 10 by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electromechanical sensor 20. The output device receives the electrical signals for assessing a level of contact between the electrode 10 and a tissue 12.

    摘要翻译： 公开了用于评估用于组织消融的电极组织接触的系统和方法。 示例性电极接触感测系统包括容纳在导管轴14的远端部分内的电极10。 至少一个机电传感器20与导管轴14内的电极10可操作地相关联。 至少一个机电传感器20通过产生对应于移动量的电信号来响应电极10的运动。 该系统还可以包括电连接到至少一个机电传感器20的输出装置。 输出装置接收用于评估电极10和组织12之间的接触水平的电信号。

    Contact sensing flexible conductive polymer electrode
    7.
    发明授权
    Contact sensing flexible conductive polymer electrode 有权
    接触感应柔性导电聚合物电极

    公开(公告)号：US08211102B2

    公开(公告)日：2012-07-03

    申请号：US11963321

    申请日：2007-12-21

    申请人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

    发明人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

    IPC分类号： A61B18/14

    CPC分类号： G01L1/16 ,  A61B5/042 ,  A61B5/6885 ,  G01L5/0038 ,  Y10T29/49002

    摘要： A contact sensing catheter system includes a catheter shaft having a distal end; a flexible conductive polymer electrode located at the distal end of the shaft; and an electro-mechanical contact sensor positioned at least partially within the electrode. The sensor outputs an electrical signal in response to a mechanical force acting thereon. The sensor may be a piezoelectric sensor, a strain gauge, a fiber optic sensor, or another suitable electro-mechanical contact sensor. The electrical signal output by the sensor typically varies in response to variations in the mechanical force acting on the sensor. An output device may receive the signal output by the contact sensor and present to a user of the system an indicator of contact between the electrode and a tissue by assessing, for example, the amplitude or periodicity of the signal.

    摘要翻译： 接触感测导管系统包括具有远端的导管轴; 位于所述轴的远端的柔性导电聚合物电极; 以及至少部分地位于电极内的电 - 机械接触传感器。 传感器响应于作用在其上的机械力而输出电信号。 传感器可以是压电传感器，应变片，光纤传感器或另一适合的机电接触传感器。 由传感器输出的电信号通常响应于作用在传感器上的机械力的变化而变化。 输出装置可以接收由接触传感器输出的信号并且通过评估例如信号的幅度或周期性向系统的用户呈现电极和组织之间的接触的指示。

    Contact Sensing Flexible Conductive Polymer Electrode
    8.
    发明申请
    Contact Sensing Flexible Conductive Polymer Electrode 有权
    接触感应柔性导电聚合物电极

    公开(公告)号：US20090158852A1

    公开(公告)日：2009-06-25

    申请号：US11963321

    申请日：2007-12-21

    申请人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

    发明人： Saurav Paul ,  Chou Thao ,  Troy T. Tegg

    IPC分类号： G01L9/00 ,  H01S4/00

    CPC分类号： G01L1/16 ,  A61B5/042 ,  A61B5/6885 ,  G01L5/0038 ,  Y10T29/49002

    摘要： A contact sensing catheter system includes a catheter shaft having a distal end; a flexible conductive polymer electrode located at the distal end of the shaft; and an electromechanical contact sensor positioned at least partially within the electrode. The sensor outputs an electrical signal in response to a mechanical force acting thereon. The sensor may be a piezoelectric sensor, a strain gauge, a fiber optic sensor, or another suitable electromechanical contact sensor. The electrical signal output by the sensor typically varies in response to variations in the mechanical force acting on the sensor. An output device may receive the signal output by the contact sensor and present to a user of the system an indicator of contact between the electrode and a tissue by assessing, for example, the amplitude or periodicity of the signal.

    摘要翻译： 接触感测导管系统包括具有远端的导管轴; 位于所述轴的远端的柔性导电聚合物电极; 以及至少部分地位于电极内的机电接触传感器。 传感器响应于作用在其上的机械力而输出电信号。 传感器可以是压电传感器，应变计，光纤传感器或另一适合的机电接触传感器。 由传感器输出的电信号通常响应于作用在传感器上的机械力的变化而变化。 输出装置可以接收由接触传感器输出的信号，并通过评估例如信号的幅度或周期性向系统的用户呈现电极和组织之间的接触的指示。

    System for electroporation therapy
    9.
    发明授权
    System for electroporation therapy 有权
    电穿孔治疗系统

    公开(公告)号：US09289606B2

    公开(公告)日：2016-03-22

    申请号：US12874788

    申请日：2010-09-02

    申请人： Saurav Paul ,  Troy T. Tegg ,  Israel A. Byrd ,  Riki Thao ,  Harry A. Puryear ,  Linda Nemec ,  John M. Berns

    发明人： Saurav Paul ,  Troy T. Tegg ,  Israel A. Byrd ,  Riki Thao ,  Harry A. Puryear ,  Linda Nemec ,  John M. Berns

    IPC分类号： A61B18/18 ,  A61N1/32 ,  A61B18/14 ,  A61B18/00

    CPC分类号： A61N1/327 ,  A61B18/14 ,  A61B2018/0016

    摘要： Catheter systems include direction-sensitive, multi-polar tip electrode assemblies for electroporation-mediated therapy, electroporation-induced primary necrosis therapy and electric field-induced apoptosis therapy, including configurations for producing narrow, linear lesions as well as distributed, wide area lesions. A monitoring system for electroporation therapy includes a mechanism for delivering electrochromic dyes to a tissue site as well as a fiber optic arrangement to optically monitor the progress of the therapy as well as to confirm success post-therapy. A fiber optic temperature sensing electrode catheter includes a tip electrode having a cavity whose inner surface is impregnated or coated with thermochromic/thermotropic material that changes color with changes in temperature. An optic fiber/detector arrangement monitors the thermochromic or thermotropic materials, acquiring a light signal and generating an output signal indicative of the spectrum of the light signal. An analyzer determines an electrode temperature based on the detector output and predetermined spectrum versus temperature calibration data.

    摘要翻译： 导管系统包括用于电穿孔介导治疗的方向敏感的多极尖端电极组件，电穿孔诱导的原发性坏死治疗和电场诱导的凋亡治疗，包括用于产生狭窄的线性损伤以及分布的广泛区域损伤的构造。 用于电穿孔治疗的监测系统包括将电致变色染料递送到组织部位的机制以及光学配置以光学监测治疗进展以及确认疗法后的成功。 光纤温度感测电极导管包括具有腔体的尖端电极，其内表面被浸渍或涂覆有随着温度变化而改变颜色的热变色/热致变色材料。 光纤/检测器装置监测热致变色或热致变色材料，获取光信号并产生指示光信号光谱的输出信号。 分析仪基于检测器输出和预定的频谱对温度校准数据来确定电极温度。