Delivery of biological compounds to ischemic and/or infarcted tissue
    62.
    发明授权
    Delivery of biological compounds to ischemic and/or infarcted tissue 有权
    向缺血和/或梗死组织递送生物化合物

    公开(公告)号:US09332893B2

    公开(公告)日:2016-05-10

    申请号:US14452268

    申请日:2014-08-05

    Abstract: The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.

    Abstract translation: 在本文中描述了将生物化合物递送至缺血和/或梗死组织,其中这样的系统可以包括展开导管和可展开成扩展构型的附接成像罩。 在使用中,成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。 半透明或透明的液体(例如盐水)可被泵送到成像罩中,直到流体移动任何血液,从而留下通过展开导管中的成像元件成像的组织的清晰区域。 此外,任何数量的治疗工具也可以通过展开导管并进入成像罩,以在组织上执行任何数量的程序,用于识别,定位和/或获取缺血和/或梗死组织。

    Integral Electrode Placement and Connection Systems
    64.
    发明申请
    Integral Electrode Placement and Connection Systems 审中-公开
    整体电极放置和连接系统

    公开(公告)号:US20150073409A1

    公开(公告)日:2015-03-12

    申请号:US14538594

    申请日:2014-11-11

    Abstract: Electrode placement and connection systems are described which allow for the electrical connection and maintenance of one or more electrodes positioned on a substrate which is subjected to a variety of mechanical stresses. Electrodes may also be formed on flexible circuit assemblies integrated within or along the hood. The circuit assemblies may also provide structural support to the hood during delivery and/or deployment. Such a system may include an imaging hood having an aperture through which transparent fluid is flowed and one or more electrodes positioned along or about the hood. As the hood is configured between a low-profile and opened configuration, these electrodes may remain electrically coupled despite the mechanical stresses subjected to the electrodes and the connections thereto.

    Abstract translation: 描述了电极放置和连接系统,其允许位于经受各种机械应力的基板上的一个或多个电极的电连接和维护。 电极也可以形成在集成在罩内或沿着罩的柔性电路组件上。 电路组件还可以在传送和/或展开期间向罩提供结构支撑。 这样的系统可以包括具有孔的成像罩,透明液体通过所述孔流动,并且一个或多个电极沿着或围绕罩定位。 由于罩被配置在低轮廓和打开的构型之间,尽管机械应力受到电极及其连接,但是这些电极可以保持电耦合。

    Delivery Of Biological Compounds To Ischemic And/Or Infarcted Tissue
    65.
    发明申请
    Delivery Of Biological Compounds To Ischemic And/Or Infarcted Tissue 审中-公开
    向缺血和/或梗塞组织递送生物化合物

    公开(公告)号:US20140350412A1

    公开(公告)日:2014-11-27

    申请号:US14452268

    申请日:2014-08-05

    Abstract: The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.

    Abstract translation: 在本文中描述了将生物化合物递送至缺血和/或梗死组织,其中这样的系统可以包括展开导管和可展开成扩展构型的附接成像罩。 在使用中,成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。 半透明或透明的液体(例如盐水)可被泵送到成像罩中,直到流体移动任何血液,从而留下通过展开导管中的成像元件成像的组织的清晰区域。 此外,任何数量的治疗工具也可以通过展开导管并进入成像罩,以在组织上执行任何数量的程序,用于识别,定位和/或获取缺血和/或梗死组织。

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