公开(公告)号：US12122906B2

公开(公告)日：2024-10-22

申请号：US17711193

申请日：2022-04-01

申请人： Joseph P. Kennedy ,  Weinan Xu

发明人： Joseph P. Kennedy ,  Weinan Xu

IPC分类号： C08L53/02 ,  B33Y70/00 ,  C08L71/02 ,  C09D153/02 ,  C09D171/02 ,  B29C64/118 ,  B29K9/06

CPC分类号： C08L53/02 ,  B33Y70/00 ,  C08L71/02 ,  C09D153/02 ,  C09D171/02 ,  B29C64/118 ,  B29K2009/06

摘要： A 3D-printable blend comprising a thermoplastic elastomer and a polymer. The thermoplastic elastomer is selected from poly(styrene-b-isobutylene-b-styrene) (SIBS), poly(St-b-butadiene-b-St) (SBS), poly(St-b-isoprene-b-St) (SIS), and their hydrogenated derivatives. The polymer is selected from polystyrene (PSt), poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) and blends of PSt and PPO. The blends may be made into filaments suitable for use in the production of 3D printed articles.

公开(公告)号：US10889712B2

公开(公告)日：2021-01-12

申请号：US16134137

申请日：2018-09-18

申请人： Joseph P. Kennedy ,  Turgut Nugay ,  Nihan Nugay

发明人： Joseph P. Kennedy ,  Turgut Nugay ,  Nihan Nugay

IPC分类号： C08L53/02 ,  C08F297/04 ,  C08F293/00

摘要： A thermoplastic elastomeric network is taught. The thermoplastic elastomer network includes hyperbranched styrenic block copolymers and styrenic block copolymers physically crosslinked though aggregation. Additionally, the hyperbranched styrenic block copolymers of the thermoplastic elastomeric network are a plurality of styrenic block copolymers chemically crosslinked.

公开(公告)号：US10774185B2

公开(公告)日：2020-09-15

申请号：US16257582

申请日：2019-01-25

申请人： Joseph P. Kennedy ,  Turgut Nugay ,  Nihan Nugay ,  Tejal J. Deodhar ,  Susan Dollinger

发明人： Joseph P. Kennedy ,  Turgut Nugay ,  Nihan Nugay ,  Tejal J. Deodhar ,  Susan Dollinger

IPC分类号： C08F8/08 ,  C08G81/02 ,  C08F220/18 ,  C08G65/08 ,  C08G77/442 ,  C07C13/547 ,  C07C13/45 ,  C08G65/14 ,  C08F110/10 ,  C08F293/00 ,  C08F4/16 ,  C08F212/08 ,  C08F210/10

摘要： In various embodiments, the present invention is directed to a centrally-functionalizable living cationic polymer or copolymer having a centrally-substituted tetraene group having the formula wherein each R is selected from the group consisting of a polymer or a copolymer, such as a polyisobutylene polymer or a poly(isobutylene-b-styrene) copolymer.

公开(公告)号：US09527964B2

公开(公告)日：2016-12-27

申请号：US14396951

申请日：2013-04-24

申请人： Li Jia ,  Joseph P. Kennedy ,  Joseph Scavuzzo

发明人： Li Jia ,  Joseph P. Kennedy ,  Joseph Scavuzzo

IPC分类号： C08G77/42 ,  C08F10/06 ,  C08F10/10 ,  C08F12/08 ,  C08F22/10 ,  C08F36/06 ,  C08F36/08 ,  C08G77/388 ,  C08G81/02 ,  C08G69/08 ,  C08G69/10

CPC分类号： C08G77/42 ,  C08F10/06 ,  C08F10/10 ,  C08F12/08 ,  C08F22/10 ,  C08F36/06 ,  C08F36/08 ,  C08G69/08 ,  C08G69/10 ,  C08G77/388 ,  C08G81/024

摘要： The present invention is generally directed to a new class of TPEs made from peptide terminated low Tg polymers and methods for making them. The middle block of these TPE is a telechelic polymer with a Tg that is below the intended service temperature of the TPE. The terminal peptide segments of these TPEs are short (from about 1 to about 10 amino acids long) and tend to from sheet type secondary structures through intermolecular hydrogen bonds, creating physical crosslinks between polymer chains. The dissimilarity of the peptide hard component and the elastomeric soft component results in very strong segregation between the microphase domains and a low plastic deformation for the resulting TPE. And since the Tm of the crystalline peptide phase can be adjusted, these new TPEs may be tailored to fit the intended service temperature and are melt-processable.

摘要翻译： 本发明一般涉及由肽封端的低Tg聚合物制成的新一类TPE及其制备方法。 这些TPE的中间嵌段是Tg值低于TPE预期使用温度的遥爪聚合物。 这些TPE的末端肽段是短的（约1至约10个氨基酸长），并且倾向于通过分子间氢键从片状二级结构产生，从而在聚合物链之间产生物理交联。 肽硬组分和弹性体软组分的不相似性导致微相区域之间非常强的偏析和所得TPE的低塑性变形。 并且由于可以调节结晶肽相的Tm，所以这些新的TPE可以被调整以适应预期的使用温度并且是可熔融加工的。

公开(公告)号：US08889926B2

公开(公告)日：2014-11-18

申请号：US14130079

申请日：2012-07-02

申请人： Joseph P. Kennedy ,  Gabor Erdodi

发明人： Joseph P. Kennedy ,  Gabor Erdodi

IPC分类号： C07C17/16 ,  C07C17/35 ,  C07C29/132 ,  C07C2/86 ,  C07C407/00 ,  C07C15/02 ,  C08F110/10 ,  C07C22/04 ,  C08F110/00

CPC分类号： C07C17/16 ,  C07C2/861 ,  C07C15/02 ,  C07C17/35 ,  C07C22/04 ,  C07C29/132 ,  C07C407/00 ,  C07C2527/128 ,  C08F110/00 ,  C08F110/10 ,  C08F4/00 ,  C07C409/12 ,  C07C33/26

摘要： A method for the synthesis of 1,3-di(chloropropyl)-5-tert-butyl benzene includes the steps of conducting Friedl-Crafts alkylation of 1,3-diisopropyl benzene by tert-butyl chloride in the presence of an alkylation catalyst to obtain 1-tert-butyl-3,5-diisopropylbenzene; peroxidizing the 1-tert-butyl-3,5-diisopropyl benzene by gaseous oxygen in the presence of a peroxidation catalyst in a basic solution to obtain 1,3-di(peroxypropyl)-5-tert-butylbenzene; reducing the 1,3-di(peroxypropyl)-5-tert-butylbenzene with a reducing agent to 1,3-di(hydroxylpropyl)-5-tert-butylbenzene; and chlorinating the 1,3-di(hydroxypropyl)-5-tert-butylbenzene to obtain 1,3-di(chloropropyl)-5-tert-butyl benzene.

摘要翻译： 合成1,3-二（氯丙基）-5-叔丁基苯的方法包括以下步骤：在烷基化催化剂存在下，用叔丁基氯进行1,3-二异丙基苯的Fried-Crafts烷基化， 得到1-叔丁基-3,5-二异丙基苯; 在碱性溶液中，在过氧化催化剂存在下，用气态氧过氧化1-叔丁基-3,5-二异丙基苯，得到1,3-二（过氧丙基）-5-叔丁基苯; 用还原剂将1,3-二（过氧丙基）-5-叔丁基苯还原成1,3-二（羟基丙基）-5-叔丁基苯; 并将1,3-二（羟丙基）-5-叔丁基苯氯化，得到1,3-二（氯丙基）-5-叔丁基苯。

公开(公告)号：US08702810B2

公开(公告)日：2014-04-22

申请号：US12529732

申请日：2008-03-10

申请人： Joseph P. Kennedy ,  Gabor Erdodi ,  Mukerrem Cakmak ,  Baris Yalcin ,  Jungmee Kang

发明人： Joseph P. Kennedy ,  Gabor Erdodi ,  Mukerrem Cakmak ,  Baris Yalcin ,  Jungmee Kang

IPC分类号： A61F2/02 ,  A61K9/24

CPC分类号： A61K9/0024 ,  A61F2/022

摘要： The present invention generally relates to implantable devices for producing insulin in diabetic animals and to methods of making same. Some embodiments include amphiphilic biomembranes for use in biological applications (e.g., as an alternative and/or supplemental insulin source). Some embodiments also include live insulin-producing cells contained within one or more amphiphilic membranes so as to prevent or diminish an immuno-response and/or rejection by the host.

摘要翻译： 本发明一般涉及用于在糖尿病动物中产生胰岛素的可植入装置及其制备方法。 一些实施方案包括用于生物应用的两亲生物膜（例如，作为替代和/或补充胰岛素源）。 一些实施方案还包括含在一个或多个两亲膜内的活的产生胰岛素的细胞，以便防止或减少宿主的免疫应答和/或排斥。

公开(公告)号：US08569420B2

公开(公告)日：2013-10-29

申请号：US12665690

申请日：2008-06-19

申请人： Joseph P. Kennedy ,  Subramanyam Ummadisetty

发明人： Joseph P. Kennedy ,  Subramanyam Ummadisetty

IPC分类号： C08F4/00 ,  C08F136/20

CPC分类号： C08F10/10 ,  C08F8/12 ,  C08F8/20 ,  C08F8/26 ,  C08F8/30 ,  C08F110/10 ,  C08F210/10 ,  C08F2810/30 ,  C08F2810/40 ,  C08F220/14

摘要： The present invention generally relates to singly-terminated polyisobutylene (PIB) compounds, and to a process for making such compounds. In one embodiment, the present invention relates to singly-terminated polyisobutylene compounds that contain only one primary alcohol, amine, or methacrylate group as the single-terminating group. In another embodiment, the present invention relates to singly-terminated polyisobutylenes carrying exactly one terminal alcohol, amine, or methacrylate group, where such singly-terminated polyisobutylenes have a number average molecular weight of about 500 to about 5000 grams per mole. In still another embodiment, the present invention relates to singly-terminated polyisobutylene compounds that can be used to synthesize polyurethanes, to polyurethane compounds made via the use of such polyisobutylene compounds, and to processes for making such compounds.

摘要翻译： 本发明一般涉及单封端的聚异丁烯（PIB）化合物，以及制备这些化合物的方法。 在一个实施方案中，本发明涉及单一封端的聚异丁烯化合物，其仅含有一个伯醇，胺或甲基丙烯酸酯基团作为单末端基团。 在另一个实施方案中，本发明涉及具有一个末端醇，胺或甲基丙烯酸酯基团的单末端聚异丁烯，其中这种单端封聚异丁烯的数均分子量为约500至约5000克/摩尔。 在另一个实施方案中，本发明涉及可用于合成聚氨酯的单末端聚异丁烯化合物，涉及通过使用这种聚异丁烯化合物制备的聚氨酯化合物，以及制备此类化合物的方法。

公开(公告)号：US08344170B2

公开(公告)日：2013-01-01

申请号：US10525284

申请日：2003-08-15

申请人： Joseph P. Kennedy ,  Pious Kurian

发明人： Joseph P. Kennedy ,  Pious Kurian

IPC分类号： C07F7/08 ,  C08G77/08

CPC分类号： C08G77/50 ,  C07F7/21 ,  C08G77/04

摘要： A poly(cyclosiloxane) network comprises the hydrosilation reaction product of a cyclosiloxane of the formula (I) wherein R and R2 are the same or different for each siloxane moiety of hydrogen, an alkyl group, an aryl group, and a cycloalkyl group, and wherein n is an integer from 3 to 8, wherein the cyclosiloxanes are joined by moieties selected from the group consisting of oxygen atoms, linear silanols, branched silanols, halosilanes, alkoxysilanes, vinyl silanes, allyl silanes, vinyl siloxanes, and allyl siloxanes, wherein the Si—O bonds of the cyclosiloxanes are substantially unrearranged compared to the cyclosiloxane precursors of the network. A process for the preparation of a poly(cyclosiloxane) network comprises providing a cyclosiloxane; providing a crosslinking group selected from the group consisting of linear silanols, branched silanols, halosilanes, alkoxysilanes, vinyl silanes, allyl silanes, vinyl siloxanes, and allyl siloxanes; contacting the cyclosiloxane and crosslinking group under condensation reaction conditions such that the crosslinking groups provide Si—O—Si linkages between the cyclosiloxane moieties to form a poly(cyclosiloxane) network composition.

摘要翻译： 聚（环硅氧烷）网络包括式（I）的环硅氧烷的氢硅化物反应产物，其中R和R 2对于氢，烷基，芳基和环烷基的每个硅氧烷部分相同或不同，以及 其中n为3至8的整数，其中环硅氧烷通过选自氧原子，直链硅烷醇，支链硅烷醇，卤代硅烷，烷氧基硅烷，乙烯基硅烷，烯丙基硅烷，乙烯基硅氧烷和烯丙基硅氧烷的部分连接，其中 与网络的环硅氧烷前体相比，环硅氧烷的Si-O键基本上未被分层。 制备聚（环硅氧烷）网络的方法包括提供环硅氧烷; 提供选自直链硅烷醇，支链硅烷醇，卤代硅烷，烷氧基硅烷，乙烯基硅烷，烯丙基硅烷，乙烯基硅氧烷和烯丙基硅氧烷的交联基团; 在缩合反应条件下使环硅氧烷和交联基团接触，使得交联基团在环硅氧烷部分之间提供Si-O-Si键，以形成聚（环硅氧烷）网络组合物。

公开(公告)号：US08258200B2

公开(公告)日：2012-09-04

申请号：US12792644

申请日：2010-06-02

申请人： Joseph P. Kennedy ,  Ummadisetty Subramanyam

发明人： Joseph P. Kennedy ,  Ummadisetty Subramanyam

IPC分类号： C08G77/442

CPC分类号： G02B1/043 ,  C08G18/289 ,  C08G18/6212 ,  C08G18/755 ,  C08G77/388 ,  C08G77/458 ,  C08J3/28 ,  C08J2383/10 ,  C08J2387/00 ,  G02B1/04 ,  C08L83/10 ,  C08L75/00

摘要： The present invention relates to the production of copolymer networks, or co-networks, and to methods for preparing copolymer or co-networks. Furthermore, the present invention relates to products and/or films made from the copolymer and/or co-networks produced in accordance with the synthesis methods of the present invention. Additionally, the present invention relates to crosslinked copolymer and/or co-networks comprising at least one hydrophilic segment and at least one hydrophobic segment. In one embodiment, the hydrophilic segments include at least one poly(vinyl alcohol) (e.g., a poly(vinyl alcohol) modified with acryl amide groups) and the hydrophobic segments include at least one polysiloxane having at least one terminal —OH group (e.g., polydimethylsiloxane (PDMS)). In another embodiment, the copolymer and/or co-networks of the present invention are optically clear and highly oxophilic.

摘要翻译： 本发明涉及共聚物网络或共网络的制备，以及制备共聚物或共网络的方法。 此外，本发明涉及由根据本发明的合成方法制备的共聚物和/或共网络制备的产品和/或膜。 另外，本发明涉及包含至少一个亲水链段和至少一个疏水链段的交联共聚物和/或共网络。 在一个实施方案中，亲水性链段包括至少一种聚（乙烯醇）（例如，用丙烯酰胺基团改性的聚（乙烯醇）），并且疏水链段包括至少一个具有至少一个末端-OH基团的聚硅氧烷（例如 ，聚二甲基硅氧烷（PDMS））。 在另一个实施方案中，本发明的共聚物和/或共网络是光学透明且高亲氧性的。

公开(公告)号：US08247515B2

公开(公告)日：2012-08-21

申请号：US12376171

申请日：2007-08-03

申请人： Joseph P. Kennedy ,  Gabor Erdodi

发明人： Joseph P. Kennedy ,  Gabor Erdodi

IPC分类号： C08G77/08

CPC分类号： C08L33/26 ,  C08K5/549 ,  C08L83/04 ,  C08L2312/00 ,  C08L83/00

摘要： The present invention generally relates to amphiphilic grafts and co-networks made from at least one hydrophilic polymer and at least one hydrophobic polymer, and to processes for preparing such amphiphilic grafts and co-networks. In another embodiment, the present invention relates to amphiphilic co-networks formed from the combination of at least one polysiloxane and at least one polyacrylamide. In yet another embodiment, the present invention relates to amphiphilic co-networks formed from the combination of at least one polysiloxane, at least one polyacrylamide and at least one crosslinking agent.

摘要翻译： 本发明一般涉及由至少一种亲水性聚合物和至少一种疏水性聚合物制成的两亲移植物和共网络，以及制备这种两亲移植物和共网络的方法。 在另一个实施方案中，本发明涉及由至少一种聚硅氧烷和至少一种聚丙烯酰胺的组合形成的两亲性共网络。 在另一个实施方案中，本发明涉及由至少一种聚硅氧烷，至少一种聚丙烯酰胺和至少一种交联剂的组合形成的两亲性共网络。