Process for preparing 1,2,4-triazole derivatives
    61.
    发明授权
    Process for preparing 1,2,4-triazole derivatives 失效
    制备1,2,4-三唑衍生物的方法

    公开(公告)号:US4123437A

    公开(公告)日:1978-10-31

    申请号:US773026

    申请日:1977-02-28

    CPC分类号: C07F9/65183 C07D249/12

    摘要: 1,2,4-TRIAZOLE DERIVATIVES WHICH HAVE PARTICULAR IMPORTANCE AS INTERMEDIATES FOR, E.G., THE PREPARATION OF ACTIVE SUBSTANCES FOR PEST CONTROL, CORRESPONDING TO THE FORMULA ##STR1## wherein R.sup.1 represents an unsubstituted or substituted alkyl, alkenyl, or alkynyl, naphthyl, benzyl, phenylethyl, ##STR2## or phenylpropyl radical, or a mono or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member, or a substituted phenyl radical,And new processes for the preparation of compounds of the formula ##STR3## wherein R represents hydrogen, an optionally substituted alkyl, alkenyl or alkynyl radical, an optionally substituted phenyl, naphthyl, benzyl, phenylethyl or phenylpropyl radical, a mono- or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member and/or be substituted by alkyl, or a partially hydrogenated naphthyl radical, which processes are performed by addition to a hydrazine of the formulaR -- NH--NH.sub.2or to a hydrazone of the formula ##STR4## wherein R has the above given meaning, R.sub.1 represents hydrogen or lower alkyl and R.sub.2 represents lower alkyl, of an alkoxy-carbonyl-isothiocyanate of the formulaalkyl--O--CO--NCSand subsequent closure of the triazole ring in the resulting thiosemicarbazide of the formula ##STR5## by the splitting-off of an alkanol (alkyl--OH), are disclosed.

    摘要翻译: 具有特异性重要性的1,2,4-三唑衍生物作为EG的中间体,用于制备用于病虫害控制的活性物质,对应于本发明的化合物,其中R 1表示未取代或取代的烷基,烯基或炔基,萘基, 苄基,苯基乙基,苯丙基或可以通过亚烷基桥基或取代的苯基结合的单环或多环环烷基,以及用于制备化合物的新方法 其中R表示氢,任选取代的烷基,烯基或炔基,任选取代的苯基,萘基,苄基,苯基乙基或苯基丙基,可以通过亚烷基桥连接体和/或 被烷基或部分氢化的萘基取代,该方法通过加入式R-NH-NH 2的肼或加成式的腙进行 其中R具有上述给定含义,R 1表示氢或低级烷基,R 2表示低级烷基,式ALKYL-O-CO-NCS的烷氧羰基 - 异硫氰酸酯,随后在三 公开了通过分解链烷醇(烷基-OH)得到的式“IMAGE”的氨基硫脲。

    O,S-dialkyl- and O-alkyl-S-alkoxyalkyl-S-1,2,4-oxa-diazolyl-3-methylene
dithiophosphates
    62.
    发明授权
    O,S-dialkyl- and O-alkyl-S-alkoxyalkyl-S-1,2,4-oxa-diazolyl-3-methylene dithiophosphates 失效
    O,S-二烷基 - 和O-烷基-S-烷氧基烷基-S-1,2,4-氧杂 - 二唑基-3-亚甲基二硫代磷酸酯

    公开(公告)号:US4028377A

    公开(公告)日:1977-06-07

    申请号:US517359

    申请日:1974-10-23

    IPC分类号: A01N57/16 C07F9/653 C07F9/165

    CPC分类号: A01N57/16 C07F9/65318

    摘要: 1,2,4-Oxadiazoles, their manufacture and use as active ingredients in pesticides especially insecticides and acaricides. The compounds correspond to the formula ##STR1## wherein R.sub.1 represents hydrogen, unsubstituted alkyl, benzyl or phenyl, R.sub.2 represents methyl or ethyl, and R.sub.3 represents unsubstituted C.sub.1 -C.sub.7 alkyl optionally interrupted by oxygen or represents C.sub.3 -C.sub.4 alkenyl.

    摘要翻译: 1,2,4-恶二唑,其制造和用作农药,特别是杀虫剂和杀螨剂中的有效成分。 该化合物对应于下式:其中R 1表示氢,未取代的烷基,苄基或苯基,R 2表示甲基或乙基,R 3表示任选被氧中断或表示C 3 -C 4烯基的未取代的C 1 -C 7烷基。

    1,2,4-Triazolyl-phosphoric and -phosphonic acid esters
    63.
    发明授权
    1,2,4-Triazolyl-phosphoric and -phosphonic acid esters 失效
    1,2,4-三唑基 - 磷酸和膦酸酯

    公开(公告)号:US3992399A

    公开(公告)日:1976-11-16

    申请号:US422038

    申请日:1973-12-05

    摘要: 1,2,4-Triazolylphosphoric and 1,2,4-triazolylphosphonic acid esters of the formula ##SPC1##Wherein R.sub.1 represents hydrogen, alkyl, cycloalkyl, phenyl, benzyl, or phenethyl, R.sub.2 represents substituted phenyl, benzyl, phenethyl, or unsubstituted diphenylmethyl, .beta.-naphthyl, or ##SPC2##R.sub.3 represents alkyl, alkoxy, alkylthio, amino, monoalkylamino or dialkylamino, R.sub.4 represents alkyl, and X represents oxygen or sulphur, a process for their manufacture and their use in pest control.

    摘要翻译: 1,2,4-三唑基磷酸和式+ q,10的1,2,4-三唑基膦酸酯,其中R1表示氢,烷基,环烷基,苯基,苄基或苯乙基,R2表示取代的苯基,苄基,苯乙基或 未取代的二苯基甲基,β-萘基或+ q,11 R 3表示烷基,烷氧基,烷硫基,氨基,单烷基氨基或二烷基氨基,R 4表示烷基,X表示氧或硫,其制备方法及其在害虫防治中的应用。

    Sulfonylureas
    65.
    发明授权
    Sulfonylureas 失效
    磺脲类

    公开(公告)号:US5597779A

    公开(公告)日:1997-01-28

    申请号:US419307

    申请日:1995-04-10

    申请人: Willy Meyer

    发明人: Willy Meyer

    摘要: N-Phenylsulfonyl-N'-pyrimidinylureas and -thioureas of formula I ##STR1## in which X is oxygen, sulfur, SO or SO.sub.2 ; W is oxygen or sulfur; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen, fluorine, chlorine, bromine, iodine, (X).sub.n R.sub.3, NO.sub.2, NR.sub.4 R.sub.5, ##STR2## or cyano; n is the number 0 or 1; R.sub.3 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkyl which is substituted by 1-4 halogen atoms, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio; or C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkenyl which is substituted by 1-4 halogen atoms; R.sub.4 is hydrogen, CH.sub.3 O, CH.sub.3 CH.sub.2 O or C.sub.1 -C.sub.3 alkyl; R.sub.5 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.6 is hydrogen, methyl or ethyl; R.sub.7 is hydrogen or methyl; Z is ##STR3## E is methine; R.sub.8 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, halogen, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkoxyalkoxy, amino, C.sub.1 -C.sub.3 alkylamino or di(C.sub.1 -C.sub.3 alkyl)amino; R.sub.9 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkoxyalkoxy, C.sub.2 -C.sub.5 alkylthioalkyl or cyclopropyl; and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases have good pre- and postemergence selective herbicidal and growth-regulating properties.

    摘要翻译: 式I的N-苯基磺酰基-N'-嘧啶基脲和硫脲其中X是氧,硫,SO或SO 2; W是氧或硫; R1是氢或甲基; R2是氢,氟,氯,溴,碘,(X)nR3,NO2,NR4R5,或氰基; n是数字0或1; R3是被1-4个卤素原子取代的C1-C4烷基或C1-C4烷基,C1-C3烷氧基或C1-C3烷硫基; 或被1-4个卤素原子取代的C 2 -C 4烯基或C 2 -C 4烯基; R4是氢,CH3O,CH3CH2O或C1-C3烷基; R5是氢或C1-C3烷基; R6是氢,甲基或乙基; R7是氢或甲基; Z是 Z1E是次甲基; R8是C1-C4烷基,C1-C4烷氧基,C1-C4卤代烷氧基,C1-C4卤代烷基,C1-C4卤代烷硫基,C1-C4烷硫基,卤素,C2-C5烷氧基烷基,C2-C5烷氧基烷氧基,氨基,C1-C3烷基氨基或二(C1-C3烷基) R9是C1-C4烷基,C1-C4烷氧基,C1-C4卤代烷氧基,C1-C4卤代烷硫基,C1-C4烷硫基,C2-C5烷氧基烷基,C2-C5烷氧基烷氧基,C2-C5烷硫基烷基或环丙基; 并且这些化合物与胺,碱金属或碱土金属碱或季铵碱的盐具有良好的芽前和芽后选择性除草和生长调节性质。

    Immunological detection methods
    66.
    发明授权
    Immunological detection methods 失效
    免疫检测方法

    公开(公告)号:US5563074A

    公开(公告)日:1996-10-08

    申请号:US275567

    申请日:1994-07-15

    摘要: The present invention relates to monoclonal antibodies that are distinguished by a high degree of selectivity and affinity towards triasulfurone and that are therefore outstandingly suitable for use in an immunoassay for the rapid and effective detection of triasulfurone. The present invention relates also to hybridoma cell lines that produce the said monoclonal antibodies and to immunological methods for the detection of triasulfurone in soil, water or air samples using the said monoclonal antibodies and to test kits that may be used in those detection methods.

    摘要翻译: 本发明涉及通过高度选择性和对三氯嘧磺隆的亲和力而区分的单克隆抗体,因此非常适合用于免疫测定以快速有效地检测三氯磺隆。 本发明还涉及产生所述单克隆抗体的杂交瘤细胞系和使用所述单克隆抗体在土壤,水或空气样品中检测三氯嘧磺隆的免疫学方法以及可用于这些检测方法的测试试剂盒。

    Phenylsulfonylchloride intermediates useful for the preparation of
herbicidally active sulfonylureas
    67.
    发明授权
    Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas 失效
    可用于制备除草活性磺酰脲类的苯磺酰氯中间体

    公开(公告)号:US5412107A

    公开(公告)日:1995-05-02

    申请号:US154768

    申请日:1993-11-19

    申请人: Willy Meyer

    发明人: Willy Meyer

    摘要: N-Phenylsulfonyl-N'-pyrimidinyl-, -N'-triazinyl- and -N'-triazolylureas and -thioureas of formula I ##STR1## in which X is oxygen, sulfur, SO or SO.sub.2 ; W is oxygen or sulfur; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen, fluorine, chlorine, bromine, iodine, (X).sub.n R.sub.3, NO.sub.2, NR.sub.4 R.sub.5, --C.tbd.CR.sub.6, ##STR2## or cyano; n is the number 0 or 1; R.sub.3 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkyl which is substituted by 1-4 halogen atoms, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio; or C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkenyl which is substituted by 1-4 halogen atoms; R.sub.4 is hydrogen, CH.sub.3 O, CH.sub.3 CH.sub.2 O or C.sub.1 -C.sub.3 alkyl; R.sub.5 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.6 is hydrogen, methyl or ethyl; R.sub.7 is hydrogen or methyl; Z is ##STR3## E is methine or nitrogen; R.sub.8 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, haloge n, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkoxyalkoxy, amino, C.sub.1 -C.sub.3 alkylamino or di(C.sub.1 -C.sub.3 alky l)amino; R.sub.9 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkoxyalkoxy, C.sub.2 -C.sub.5 alkylthioalkyl or cyclopropyl; R.sub.10 is hydrogen, fluorine, chlorine, methyl, trifluoromethyl, CH.sub.3 O, CH.sub.3 CH.sub.2 O, CH.sub.3 S, CH.sub.3 SO, CH.sub.3 SO.sub.2 or cyano; R.sub.11 is methyl, ethyl, CH.sub.3 O, CH.sub.3 CH.sub.2 O, fluorine or chlorine; R.sub.12 is methyl, ethyl, CH.sub.3 O, CH.sub.3 CH.sub.2 O, fluorine or chlorine; R.sub.13 is C.sub.1 -C.sub.3 alkyl; and R.sub.14 is C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, chlorine or OCHF.sub.2 ; and the salts of these compounds; with the provisos that E is methine if R.sub.8 is halogen; and E is methine if R.sub.8 or R.sub.9 is OCHF.sub.2 or SCHF.sub.2, and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases have good pre- and postemergence selective herbicidal and growth-regulating properties.

    摘要翻译: 式I或SO 2的N-苯基磺酰基-N'-嘧啶基 - ,N'-三嗪基和-N'-三唑基脲和硫脲; W是氧或硫; R1是氢或甲基; R2是氢,氟,氯,溴,碘,(X)nR3,NO2,NR4R5,-C3OND CR6, n是数字0或1; R3是被1-4个卤素原子取代的C1-C4烷基或C1-C4烷基,C1-C3烷氧基或C1-C3烷硫基; 或被1-4个卤素原子取代的C 2 -C 4烯基或C 2 -C 4烯基; R4是氢,CH3O,CH3CH2O或C1-C3烷基; R5是氢或C1-C3烷基; R6是氢,甲基或乙基; R7是氢或甲基; Z是 Z1 Z2或 Z3E是次甲基或氮; R8是C1-C4烷基,C1-C4烷氧基,C1-C4卤代烷氧基,C1-C4卤代烷基,C1-C4卤代烷硫基,C1-C4烷硫基,卤代烷基,C2-C5烷氧基烷基,C2-C5烷氧基烷氧基,氨基,C1-C3烷基氨基或二(C1-C3烷基) 氨基; R9是C1-C4烷基,C1-C4烷氧基,C1-C4卤代烷氧基,C1-C4卤代烷硫基,C1-C4烷硫基,C2-C5烷氧基烷基,C2-C5烷氧基烷氧基,C2-C5烷硫基烷基或环丙基; R 10为氢,氟,氯,甲基,三氟甲基,CH 3 O,CH 3 CH 2 O,CH 3 S,CH 3 SO,CH 3 SO 2或氰基; R11为甲基,乙基,CH3O,CH3CH2O,氟或氯; R12是甲基,乙基,CH3O,CH3CH2O,氟或氯; R 13是C 1 -C 3烷基; 和R 14是C 1 -C 3烷基,C 1 -C 3烷氧基,氯或OCHF 2; 和这些化合物的盐; 条件是如果R8是卤素,E是次甲基; 如果R 8或R 9为OCHF 2或SCHF 2,则E为次甲基,并且这些化合物与胺,碱金属或碱土金属碱或季铵碱的盐具有良好的芽前和芽后选择性除草和生长调节性质。

    Sulfonylureas
    68.
    发明授权
    Sulfonylureas 失效
    磺脲类

    公开(公告)号:US5286709A

    公开(公告)日:1994-02-15

    申请号:US14947

    申请日:1993-02-08

    申请人: Willy Meyer

    发明人: Willy Meyer

    摘要: N-Phenylsulfonyl-N'-pyrimidinylureas and -thioureas of formula I ##STR1## in which X is oxygen, sulfur, SO or SO.sub.2 ; W is oxygen or sulfur; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen, fluorine, chlorine, bromine, iodine, (X).sub.n R.sub.3, NO.sub.2, NR.sub.4 R.sub.5,--C.tbd.CR.sub.6, ##STR2## or cyano; n is the number 0 or 1; R.sub.3 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkyl which is substituted by 1-4 halogen atoms, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio; or C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkenyl which is substituted by 1-4 halogen atoms; R.sub.4 is hydrogen, CH.sub.3 O, CH.sub.3 CH.sub.2 O or C.sub.1 -C.sub.3 alkyl; R.sub.5 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.6 is hydrogen, methyl or ethyl; R.sub.7 is hydrogen or methyl; Z is ##STR3## R.sub.10 is hydrogen, fluorine, chlorine, methyl, trifluoromethyl, CH.sub.3 O, CH.sub.3 CH.sub.2 O, CH.sub.3 S, CH.sub.3 SO, CH.sub.3 SO.sub.2 or cyano; R.sub.11 is methyl, ethyl, CH.sub.3 O, CH.sub.3 CH.sub.2 O, fluorine or chlorine; R.sub.12 is methyl, ethyl, CH.sub.3 O, CH.sub.3 CH.sub.2 O, fluorine or chlorine; and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases, have good pre- and postemergence selective herbicidal and growth-regulating properties.

    摘要翻译: 式I的N-苯基磺酰基-N'-嘧啶基脲和硫脲其中X是氧,硫,SO或SO 2; W是氧或硫; R1是氢或甲基; R2是氢,氟,氯,溴,碘,(X)nR3,NO2,NR4R5,-C3OND CR6, n是数字0或1; R3是被1-4个卤素原子取代的C1-C4烷基或C1-C4烷基,C1-C3烷氧基或C1-C3烷硫基; 或被1-4个卤素原子取代的C 2 -C 4烯基或C 2 -C 4烯基; R4是氢,CH3O,CH3CH2O或C1-C3烷基; R5是氢或C1-C3烷基; R6是氢,甲基或乙基; R7是氢或甲基; Z为R 2为氢,氟,氯,甲基,三氟甲基,CH 3 O,CH 3 CH 2 O,CH 3 S,CH 3 SO,CH 3 SO 2或氰基; R11为甲基,乙基,CH3O,CH3CH2O,氟或氯; R12是甲基,乙基,CH3O,CH3CH2O,氟或氯; 并且这些化合物与胺,碱金属或碱土金属碱或季铵碱的盐具有良好的芽前和芽后选择性除草和生长调节性质。

    N-phenylsulfonyl-N-triazinylureas
    70.
    发明授权
    N-phenylsulfonyl-N-triazinylureas 失效
    N-苯基磺酰基-N-三嗪基脲

    公开(公告)号:US4944794A

    公开(公告)日:1990-07-31

    申请号:US777900

    申请日:1985-09-19

    摘要: N-phenylsulfonyl-N'-triazinylureas of the general formula ##STR1## and the salts of these compounds with amines, alkali metal or alkaline-earth metal bases or with quaternary ammonium bases have good selective, pre- and post-emergence, herbicidal and growth-regulating properties.The symbols in this formula have the following meanings;A is a C.sub.1 -C.sub.6 -haloalkyl group,X is oxygen, sulfur, or a sulfinyl or sulfonyl bridge,Z is oxygen or sulfur,m is the number one or two,R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.2 -C.sub.5 -alkenyl, or a --Y--R.sub.6 group,R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.2 -C.sub.5 -alkenyl or C.sub.1 -C.sub.4 -haloalkyl, or a group --Y--R.sub.6, --COOR.sub.7, --NO.sub.2 or --CO--NR.sub.8 --R.sub.9,R.sub.3 is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylthio, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.4 -haloalkoxy, halogen or alkoxyalkyl having at most 4 carbon atoms,R.sub.4 is hydrogen, methyl or ethyl,R.sub.5 is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.3 -alkoxy, methoxymethyl, cyanomethyl or cyanoethyl,R.sub.6 and R.sub.7 are each C.sub.1 -C.sub.5 -alkyl, C.sub.2 -C.sub.5 -alkenyl or C.sub.2 -C.sub.6 -alkynyl,R.sub.8 and R.sub.9 independently of one another are each hydrogen C.sub.1 -C.sub.5 -alkyl, C.sub.2 -C.sub.5 -alkenyl or C.sub.2 -C.sub.6 -alkynyl, andY is oxygen, sulfur, or a sulfinyl or sulfonyl bridge.