利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

122 条记录 (耗时 0.028 秒)

    Systems and Methods for Ranking and Selection of Pacing Vectors
    61.
    发明申请
    Systems and Methods for Ranking and Selection of Pacing Vectors 有权
    用于起搏向量排序和选择的系统和方法

    公开(公告)号：US20110004264A1

    公开(公告)日：2011-01-06

    申请号：US12822487

    申请日：2010-06-24

    申请人： Krzysztof Z. Siejko ,  Shibaji Shome ,  Jiang Ding

    发明人： Krzysztof Z. Siejko ,  Shibaji Shome ,  Jiang Ding

    IPC分类号： A61N1/08

    CPC分类号： A61N1/3704 ,  A61N1/056 ,  A61N1/36185 ,  A61N1/36514 ,  A61N1/36542 ,  A61N1/36585 ,  A61N1/368 ,  A61N1/3686 ,  A61N1/371

    摘要： Approaches to rank potential left ventricular (LV) pacing vectors are described. Early elimination tests are performed to determine the viability of LV cathode electrodes. Some LV cathodes are eliminated from further testing based on the early elimination tests. LV cathodes identified as viable cathodes are tested further. Viable LV cathode electrodes are tested for hemodynamic efficacy. Cardiac capture and phrenic nerve activation thresholds are then measured for potential LV pacing vectors comprising a viable LV cathode electrode and an anode electrode. The potential LV pacing vectors are ranked based on one or more of the hemodynamic efficacy of the LV cathodes, the cardiac capture thresholds, and the phrenic nerve activation thresholds.

    摘要翻译： 描述了评估潜在的左心室（LV）起搏向量的方法。 执行早期消除测试以确定LV阴极的可行性。 基于早期消除测试，一些LV阴极被进一步测试消除。 确定为阴极的LV阴极被进一步测试。 测试可行的LV阴极电极的血液动力学效能。 然后测量包含可行的LV阴极电极和阳极电极的潜在LV起搏向量的心脏捕获和膈神经激活阈值。 潜在的LV起搏向量基于LV阴极的血液动力学功效，心脏捕获阈值和膈神经激活阈值中的一种或多种进行排名。

    Dual-use sensor for rate responsive pacing and heart sound monitoring
    62.
    发明授权
    Dual-use sensor for rate responsive pacing and heart sound monitoring 有权
    双用传感器用于速率响应起搏和心脏声音监测

    公开(公告)号：US07844334B2

    公开(公告)日：2010-11-30

    申请号：US11778527

    申请日：2007-07-16

    申请人： Keith R. Maile ,  Krzysztof Z. Siejko

    发明人： Keith R. Maile ,  Krzysztof Z. Siejko

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36542 ,  A61N1/36585

    摘要： An implantable medical device includes a dual-use sensor such as a single accelerometer that senses an acceleration signal. A sensor processing circuit processes the acceleration signal to produce an activity level signal and a heart sound signal. The implantable medical device provides for rate responsive pacing in which at least one pacing parameter, such as the pacing interval, is dynamically adjusted based on the physical activity level. The implantable medical device also uses the heart sounds for pacing control purposes or transmits a heart sound signal to an external system for pacing control and/or diagnostic purposes.

    摘要翻译： 可植入医疗装置包括感测加速度信号的诸如单个加速度计的双重用途传感器。 传感器处理电路处理加速度信号以产生活动度信号和心音信号。 可植入医疗装置提供速率响应起搏，其中基于身体活动水平动态地调整至少一个起搏参数，例如起搏间隔。 可植入医疗装置还使用心脏声音用于起搏控制目的，或者将心音信号发送到外部系统用于起搏控制和/或诊断目的。

    DETERMINING A PATIENT'S POSTURE FROM MECHANICAL VIBRATIONS OF THE HEART
    63.
    发明申请
    DETERMINING A PATIENT'S POSTURE FROM MECHANICAL VIBRATIONS OF THE HEART 有权
    从心脏的机械振动中确定患者的姿势

    公开(公告)号：US20090247889A1

    公开(公告)日：2009-10-01

    申请号：US12484108

    申请日：2009-06-12

    申请人： Keith R. Maile ,  Krzysztof Z. Siejko

    发明人： Keith R. Maile ,  Krzysztof Z. Siejko

    IPC分类号： A61B5/02

    CPC分类号： A61N1/36542 ,  A61B7/00 ,  A61N1/36535 ,  A61N1/36578

    摘要： A system for determining a patient's posture by monitoring heart sounds. The system comprises an implantable medical device that includes a sensor operable to produce an electrical signal representative of heart sounds, a sensor interface circuit coupled to the sensor to produce a heart sound signal, and a controller circuit coupled to the sensor interface circuit. The heart sounds are associated with mechanical activity of a patient's heart and the controller circuit is operable to detect a posture of the patient from a heart sound signal.

    摘要翻译： 通过监测心脏声音来确定患者姿势的系统。 该系统包括可植入医疗装置，其包括可操作以产生表示心脏声音的电信号的传感器，耦合到传感器以产生心音信号的传感器接口电路，以及耦合到传感器接口电路的控制器电路。 心脏声音与患者心脏的机械活动相关联，并且控制器电路可操作以从心脏声音信号检测患者的姿势。

    Trending of systolic murmur intensity for monitoring cardiac disease with implantable device
    64.
    发明授权
    Trending of systolic murmur intensity for monitoring cardiac disease with implantable device 有权
    用植入式装置监测心脏病的收缩期杂音强度的趋势

    公开(公告)号：US07404802B2

    公开(公告)日：2008-07-29

    申请号：US11122749

    申请日：2005-05-05

    申请人： Krzysztof Z. Siejko ,  Richard Fogoros

    发明人： Krzysztof Z. Siejko ,  Richard Fogoros

    IPC分类号： A61B5/02

    CPC分类号： A61N1/36514 ,  A61B7/023 ,  A61N1/3627

    摘要： Described is an implantable device configured to monitor for changes in the intensity and/or duration of a systolic murmur such as mitral regurgitation by means of an acoustic sensor. Such changes may be taken to indicate a change in a patient's heart failure status. Upon detection of a worsening in the patient's heart failure statue, the device may be programmed to alert clinical personnel over a patient management network and/or make appropriate adjustments to pacing therapy.

    摘要翻译： 描述了被配置为通过声学传感器监测收缩期杂音如二尖瓣反流的强度和/或持续时间的变化的可植入装置。 可以采取这种改变来指示患者心力衰竭状态的变化。 当检测到患者的心力衰竭雕像恶化时，该装置可以被编程以通过患者管理网络警告临床人员和/或对起搏治疗进行适当的调整。

    Systems and methods for ranking and selection of pacing vectors
    66.
    发明授权
    Systems and methods for ranking and selection of pacing vectors 有权
    起搏向量的排序和选择的系统和方法

    公开(公告)号：US08886313B2

    公开(公告)日：2014-11-11

    申请号：US12822487

    申请日：2010-06-24

    申请人： Krzysztof Z. Siejko ,  Shibaji Shome ,  Jiang Ding

    发明人： Krzysztof Z. Siejko ,  Shibaji Shome ,  Jiang Ding

    IPC分类号： A61N1/05 ,  A61N1/365 ,  A61N1/36 ,  A61N1/368 ,  A61N1/37

    CPC分类号： A61N1/3704 ,  A61N1/056 ,  A61N1/36185 ,  A61N1/36514 ,  A61N1/36542 ,  A61N1/36585 ,  A61N1/368 ,  A61N1/3686 ,  A61N1/371

    摘要： Approaches to rank potential left ventricular (LV) pacing vectors are described. Early elimination tests are performed to determine the viability of LV cathode electrodes. Some LV cathodes are eliminated from further testing based on the early elimination tests. LV cathodes identified as viable cathodes are tested further. Viable LV cathode electrodes are tested for hemodynamic efficacy. Cardiac capture and phrenic nerve activation thresholds are then measured for potential LV pacing vectors comprising a viable LV cathode electrode and an anode electrode. The potential LV pacing vectors are ranked based on one or more of the hemodynamic efficacy of the LV cathodes, the cardiac capture thresholds, and the phrenic nerve activation thresholds.

    摘要翻译： 描述了评估潜在的左心室（LV）起搏向量的方法。 执行早期消除测试以确定LV阴极的可行性。 基于早期消除测试，一些LV阴极被进一步测试消除。 确定为阴极的LV阴极被进一步测试。 测试可行的LV阴极电极的血液动力学效能。 然后测量包含可行的LV阴极电极和阳极电极的潜在LV起搏向量的心脏捕获和膈神经激活阈值。 潜在的LV起搏向量基于LV阴极的血液动力学功效，心脏捕获阈值和膈神经激活阈值中的一种或多种进行排名。

    Cardiac mechanical vibration monitor using information indicative of lead motion
    68.
    发明授权
    Cardiac mechanical vibration monitor using information indicative of lead motion 有权
    心脏机械振动监测器使用指示引导运动的信息

    公开(公告)号：US08532770B2

    公开(公告)日：2013-09-10

    申请号：US13168547

    申请日：2011-06-24

    申请人： Robert J. Sweeney ,  Allan C. Shuros ,  Krzysztof Z. Siejko ,  David C. Olson ,  Frank Ingle

    发明人： Robert J. Sweeney ,  Allan C. Shuros ,  Krzysztof Z. Siejko ,  David C. Olson ,  Frank Ingle

    IPC分类号： A61N1/365

    CPC分类号： A61N1/36514 ,  A61B5/02133 ,  A61B5/026 ,  A61N1/08 ,  A61N1/36142 ,  A61N1/36578

    摘要： Systems and methods to monitor cardiac mechanical vibrations using information indicative of lead motion are described. In an example, a system including an implantable medical device can include an excitation circuit configured to provide a non-tissue stimulating, non-therapeutic electrical excitation signal to a portion of an implantable lead. A receiver circuit can be configured to obtain information indicative of a mechanical vibration of the implantable lead due at least in part to one or more of an impact of at least a portion of the heart to the implantable lead, or friction contact between the implantable lead and cardiac tissue. The system can include a processor circuit configured to determine one or more of a lead mechanical status, or information indicative of valvular activity using the information indicative of the mechanical vibration of the implantable lead.

    摘要翻译： 描述使用指示引导运动的信息来监测心脏机械振动的系统和方法。 在一个示例中，包括可植入医疗装置的系统可以包括被配置为向可植入引线的一部分提供非组织刺激的非治疗电激励信号的激励电路。 接收器电路可以被配置为获得指示可植入引线的机械振动的信息，其至少部分地由至少一部分心脏到可植入引线的冲击或可植入引线之间的摩擦接触 和心脏组织。 该系统可以包括处理器电路，其被配置为使用指示可植入引线的机械振动的信息来确定引导机械状态或指示瓣膜活动的信息中的一个或多个。

    REMOTE SENSING IN AN IMPLANTABLE MEDICAL DEVICE
    69.
    发明申请
    REMOTE SENSING IN AN IMPLANTABLE MEDICAL DEVICE 有权
    可移植医疗设备中的远程感测

    公开(公告)号：US20130023956A1

    公开(公告)日：2013-01-24

    申请号：US13626628

    申请日：2012-09-25

    申请人： David J. Ternes ,  Krzysztof Z. Siejko ,  Stephen Ruble ,  Jason J. Hamann

    发明人： David J. Ternes ,  Krzysztof Z. Siejko ,  Stephen Ruble ,  Jason J. Hamann

    IPC分类号： A61N1/372

    CPC分类号： A61N1/36139 ,  A61B5/0255 ,  A61B5/0816 ,  A61B5/0823 ,  A61B5/1107 ,  A61B5/6869 ,  A61B2562/0219 ,  A61B2562/043 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36578

    摘要： An embodiment uses an accelerometer to sense heart sounds, and determines heart rate information using the sensed heart sounds. An embodiment uses an accelerometer to sense respiratory activity. An embodiment delivers a programmed neural stimulation therapy with a programmed duty cycle, where the programmed duty cycle includes a stimulation ON portion followed by a stimulation OFF portion. An electrode electrically connected to the implanted neural stimulation device is used to remotely detect cardiac activity. The remotely detected cardiac activity is used to detect heart rate information during the stimulation ON portion and to detect heart rate information during the stimulation OFF portion. The detected heart rate information and/or the detected respiration information are used to control a neural stimulation therapy performed by the neural stimulator device and/or are used to provide diagnostic information for the patient's condition.

    摘要翻译： 一个实施例使用加速度计来感测心脏声音，并且使用感测到的心脏声音来确定心率信息。 一个实施例使用加速计来感测呼吸活动。 实施例以编程的占空比递送编程的神经刺激疗法，其中编程的占空比包括刺激开启部分，随后是刺激关闭部分。 电连接到植入的神经刺激装置的电极用于远程检测心脏活动。 远程检测到的心脏活动用于在刺激ON部分期间检测心率信息，并在刺激OFF部分期间检测心率信息。 检测到的心率信息和/或检测到的呼吸信息用于控制由神经刺激器装置执行的神经刺激治疗和/或用于提供患者状况的诊断信息。