SAFEGUARDING MEASURES FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM
    61.
    发明申请
    SAFEGUARDING MEASURES FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM 有权
    封闭式胰岛素输注系统的保护措施

    公开(公告)号:US20140066885A1

    公开(公告)日:2014-03-06

    申请号:US13870910

    申请日:2013-04-25

    Abstract: Processor-implemented methods of controlling an insulin infusion device for a user are provided here. A first method obtains a current insulin on board (IOB) value that estimates active insulin in the user, and compensates a calculated insulin infusion rate in response to the obtained IOB value. A second method supervises the operation of a glucose sensor by obtaining and processing insulin-delivered data and glucose sensor data for the user. An alert is generated if the second method determines that a current glucose sensor value has deviated from a predicted sensor glucose value by at least a threshold amount.

    Abstract translation: 这里提供了用于控制用户的胰岛素输注装置的处理器实现的方法。 第一种方法获得当前用于估计使用者中的活性胰岛素的船上胰岛素(IOB)值,并根据获得的IOB值补偿计算的胰岛素输注速率。 第二种方法通过获得并处理用户的胰岛素递送数据和葡​​萄糖传感器数据来监视葡萄糖传感器的操作。 如果第二种方法确定当前的葡萄糖传感器值已经从预测的传感器葡萄糖值偏离了至少一个阈值量,则产生警报。

    DETERMINATION OF CARBOHYDRATE-TO-INSULIN RATIOS

    公开(公告)号:US20250166776A1

    公开(公告)日:2025-05-22

    申请号:US18917224

    申请日:2024-10-16

    Abstract: Disclosed herein are techniques related to determining medical parameters. In some embodiments, the techniques involve: obtaining a metric of insulin dosage for a patient; and determining at least one carbohydrate-to-insulin ratio for the patient based at least in part on a model and using the obtained metric of insulin dosage for the patient, wherein parameters of the model were determined based on data associated with a population of patients.

    DEFAULT CARBOHYDRATE CONSUMPTION COUNTS BASED ON POPULATION CARBOHYDRATE CONSUMPTION MODELS

    公开(公告)号:US20210398639A1

    公开(公告)日:2021-12-23

    申请号:US17336912

    申请日:2021-06-02

    Abstract: The present disclosure relates to default carbohydrate consumption counts based on population carbohydrate consumption models. Aspects of the present disclosure relate to receiving, from a device, at least one characteristic of a person; accessing a population carbohydrate consumption model which relates the at least one characteristic with carbohydrate intake for a population; determining, based on applying the population carbohydrate consumption model to the at least one characteristic, at least one of: a preliminary carbohydrate count for the person or a default carbohydrate consumption count for the person; and causing delivery of insulin to the person based on communicating, to the device, at least one of: the preliminary carbohydrate count for the person or the default carbohydrate consumption count for the person.

    Personalized closed loop medication delivery system that utilizes a digital twin of the patient

    公开(公告)号:US11158413B2

    公开(公告)日:2021-10-26

    申请号:US16386104

    申请日:2019-04-16

    Abstract: A medical device system and related method of automatically adjusting parameters of an insulin delivery controller of an insulin infusion device are disclosed. The methodology obtains therapy-related data associated with operation of the insulin infusion device for a number of days in the past, including sensor glucose data associated with glucose levels of the user, and meal data associated with identified meals. The obtained therapy-related data is processed to generate a suitable pharmacokinetic/pharmacodynamic (PK/PD) model of the user, wherein the PK/PD model fits at least some of the sensor glucose data obtained for the user. The PK/PD model can be used to calculate at least one adjusted parameter of the insulin delivery controller, based on additional therapy-related data associated with further operation of the insulin infusion device. The insulin delivery controller can be instructed or controlled to adjust its settings in accordance with the model-calculated parameters.

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