公开(公告)号：US20090157059A1

公开(公告)日：2009-06-18

申请号：US12002304

申请日：2007-12-14

申请人： Paul G. Allen ,  Edward S. Boyden ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Paul G. Allen ,  Edward S. Boyden ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： A61B17/00

CPC分类号： A61B34/75 ,  A61B34/20 ,  A61B34/25 ,  A61B34/76 ,  A61B2017/00115 ,  A61B2017/00119 ,  A61B2017/00123 ,  A61B2017/00207 ,  A61B2017/00221 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/256 ,  A61B2090/365

摘要： The disclosure pertains to a surgical system. In an embodiment, the system comprises one or more sensors operably responsive to physical boundary limitations of an operating field. Furthermore, the one or more sensors provide information regarding the physical boundary limitations of the operating field. In another embodiment, the system comprises a surgical instrument that is configured to respond to the information by either activation or inactivation. In another aspect the disclosure includes generating an anatomical image or anatomic positional reference data from one or more anatomical objects. Additionally, the method includes creating haptic feedback signals based at least partly on the anatomical image or anatomic positional reference data, and determining a position or orientation of a surgical instrument. Furthermore the method includes activating or inactivating the surgical instrument based at least partly on the haptic feedback signals.

摘要翻译： 本公开涉及外科系统。 在一个实施例中，系统包括可操作地响应于操作场的物理边界限制的一个或多个传感器。 此外，一个或多个传感器提供关于操作区域的物理边界限制的信息。 在另一个实施例中，该系统包括被配置为通过激活或失活响应于该信息的外科器械。 在另一方面，本公开包括从一个或多个解剖学对象产生解剖图像或解剖学位置参考数据。 另外，该方法包括至少部分地基于解剖图像或解剖学位置参考数据创建触觉反馈信号，以及确定外科器械的位置或取向。 此外，该方法包括至少部分地基于触觉反馈信号来激活或失活外科器械。

公开(公告)号：US20090131738A1

公开(公告)日：2009-05-21

申请号：US12319882

申请日：2009-01-12

申请人： Bran Ferren ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Bran Ferren ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： A61B17/00 ,  A61N1/36 ,  A61N2/00 ,  A61N5/00 ,  A61M37/00

CPC分类号： A61B1/00156 ,  A61B1/00158 ,  A61B1/041 ,  A61B5/0031 ,  A61B5/0059 ,  A61B5/04001 ,  A61B5/05 ,  A61B5/07 ,  A61B5/14539 ,  A61B5/4839 ,  A61N1/02 ,  A61N1/32 ,  A61N1/37205

摘要： Lumen-traveling biological interface devices and associated methods and systems are described. Lumen-traveling biological interface devices capable of traveling within a body lumen may include a propelling mechanism to produce movement of the lumen-traveling device within the lumen, electrodes or other electromagnetic transducers for detecting biological signals and electrodes, coils or other electromagnetic transducers for delivering electromagnetic stimuli to stimulus responsive tissues. Lumen-traveling biological interface devices may also include additional components such as sensors, an active portion, and/or control circuitry.

摘要翻译： 描述了流明生物界面装置及相关方法和系统。 能够在体腔内行进的流明的生物界面装置可以包括用于产生管腔中的内腔行进装置的运动的推进机构，用于检测生物信号的电极或其它电磁换能器以及用于传送的电极，线圈或其它电磁换能器 对刺激反应组织的电磁刺激。 流明生物界面装置还可以包括诸如传感器，有效部分和/或控制电路的附加部件。

公开(公告)号：US20090131737A1

公开(公告)日：2009-05-21

申请号：US12319881

申请日：2009-01-12

申请人： Bran Ferren ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Bran Ferren ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： A61B17/00 ,  A61N1/36 ,  A61N2/00 ,  A61N5/00 ,  A61M37/00

CPC分类号： A61B1/00156 ,  A61B1/00158 ,  A61B1/041 ,  A61B5/0031 ,  A61B5/0059 ,  A61B5/04001 ,  A61B5/05 ,  A61B5/07 ,  A61B5/14539 ,  A61B5/4839 ,  A61N1/02 ,  A61N1/32 ,  A61N1/37205

摘要： Lumen-traveling biological interface devices and associated methods and systems are described. Lumen-traveling biological interface devices capable of traveling within a body lumen may include a propelling mechanism to produce movement of the lumen-traveling device within the lumen, electrodes or other electromagnetic transducers for detecting biological signals and electrodes, coils or other electromagnetic transducers for delivering electromagnetic stimuli to stimulus responsive tissues. Lumen-traveling biological interface devices may also include additional components such as sensors, an active portion, and/or control circuitry.

公开(公告)号：US20090101838A1

公开(公告)日：2009-04-23

申请号：US11975702

申请日：2007-10-18

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： G01N21/64 ,  C09K11/06

CPC分类号： A61K41/0057 ,  A61K41/0019 ,  A61K41/0042

摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.

摘要翻译： 一种方法，组成和系统响应电离辐射来调节生物活性。 在一些方法中，电离辐射是产生引发生物活性反应的发光反应的X射线或极紫外辐射。

公开(公告)号：US20090086901A1

公开(公告)日：2009-04-02

申请号：US11906151

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： G01N23/223 ,  G01N23/225

CPC分类号： G01N23/223 ,  A61B5/415 ,  A61B5/418 ,  A61B5/489 ,  A61B6/12 ,  A61B6/14 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/485 ,  A61B6/50 ,  A61B6/501 ,  A61B6/502 ,  A61B6/503 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B2503/40 ,  G01N2223/076

摘要： One aspect can relate to detecting a presence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面可以涉及至少部分地基于添加至少一个个体的至少一个个体的至少一部分的至少一些物质中的至少一种化学，化合物或生物材料的存在来检测 至少部分地至少部分地基于在所述至少一种化学鉴定添加剂中产生至少一种诱导的X射线荧光光子的化学鉴定添加剂至少部分至少一部分物质的化学鉴定添加剂，其响应于 单输入能量事件，其中至少一些输入能量被施加在至少一个化学，化合物或生物材料的近端，该至少一种化学，化合物或生物材料包含在至少一个个体的至少一部分的该至少一些物质中。

公开(公告)号：US20090086896A1

公开(公告)日：2009-04-02

申请号：US11906169

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： Certain embodiments of one aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the least the portion of the at least one individual. The aspect can include X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual at least partially in response to the inducing at least one induced X-ray fluorescing photon within the at least some matter of the least the portion of the at least one individual. Certain embodiments of the aspect can include providing a substantial real time tool-based operation to the at least some matter of the least the portion of the at least one individual at least partially relying on the X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual.

摘要翻译： 一个方面的某些实施方案涉及在至少一些输入能量的至少一些输入能量的至少一个的至少一部分内的至少一些物质内诱导至少一个诱导的X射线荧光光子，所述至少一些输入能量被施加到所述至少一些 至少一个人的至少一部分的事物。 所述方面可以包括至少部分响应于诱导至少一个诱导的X射线荧光光子的至少一个个体的至少一部分内的至少一些物质内的X射线荧光可视化，成像或信息提供 所述至少一个个体的至少一部分的至少一部分。 该方面的某些实施例可以包括至少部分地依赖于X射线荧光可视化，成像或提供信息的至少一个个体的至少一部分的至少一些物质提供基本实时的基于工具的操作 在至少一个个体的至少一部分内的至少一些事物内。

公开(公告)号：US20090086892A1

公开(公告)日：2009-04-02

申请号：US11906135

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： G01N23/223 ,  G01N23/225

CPC分类号： A61B6/503 ,  A61B5/415 ,  A61B5/418 ,  A61B5/489 ,  A61B6/12 ,  A61B6/14 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/485 ,  A61B6/50 ,  A61B6/501 ,  A61B6/502 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B2503/40 ,  G01N23/223 ,  G01N2223/076

摘要： One aspect relates to detecting at least one induced X-ray fluorescing photon fluoresced from substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of receiving at least one induced X-ray fluorescing photon generated at least partially within at least one X-ray fluorescence event within the at least some matter of the at least the portion of the at least one individual which has been generated responsive to an at least some input energy resulting from a single input energy event, wherein the at least one induced X-ray fluorescing photon that has passed through the at least some matter of the at least the portion of the at least one individual is at a level to substantially limit interference between the at least one induced X-ray fluorescing photon with an at least one other induced X-ray fluorescing photon that travel for distances greater than a prescribed limit through the at least some matter of the at least the portion of the at least one individual, wherein the at least one other induced X-ray fluorescing photon attenuates by a prescribed percentage after passing through the prescribed distance through the at least some matter of the at least the portion of the at least one individual.

摘要翻译： 一个方面涉及至少部分地检测至少一个感兴趣的X射线荧光光子，其基本上在至少一个个体的至少一部分的至少一些物质内发射，作为接收至少一个诱导X射线 至少部分地在至少一个X射线荧光事件中产生荧光光子，所述至少一个X射线荧光事件在所述至少一个个体的至少一部分中的至少一些物质中响应于由单个输入产生的至少一些输入能量而产生 能量事件，其中已经通过所述至少一个个体的至少一部分的至少一些物质的所述至少一个感兴趣的X射线荧光光子处于基本上限制所述至少一个诱导X 具有至少一个其它诱导的X射线荧光光子的荧光光子，其行进距离大于规定的极限，通过至少一些事件 所述至少一个个体的部分，其中所述至少一个其它诱导的X射线荧光光子在经过所述规定距离之后通过所述至少一个的所述至少一部分的所述至少一些物质衰减预定百分比 个人。

公开(公告)号：US20090024140A1

公开(公告)日：2009-01-22

申请号：US11880432

申请日：2007-07-20

申请人： Paul G. Allen ,  Edward Boyden ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

发明人： Paul G. Allen ,  Edward Boyden ,  W. Daniel Hillis ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, JR. ,  Victoria Y.H. Wood

IPC分类号： A61B19/00

CPC分类号： A61B90/06 ,  A61B34/20 ,  A61B34/76 ,  A61B2090/033 ,  A61B2090/062 ,  A61B2090/064 ,  A61B2090/08021

摘要： The invention pertains to a surgical system. In an embodiment, the system comprises one or more sensors operably responsive to physical boundary limitations of an operating field. Furthermore, the one or more sensors provide information regarding the physical boundary limitations of the operating field. In another embodiment, the system comprises a surgical instrument that is configured to respond to the information by either activation or inactivation. In another aspect the invention includes generating an anatomical image or anatomic positional reference data. Additionally, the method includes creating haptic feedback signals based at least partly on the anatomical image or anatomic positional reference data, and determining a position or orientation of a surgical instrument. Furthermore the method includes activating or inactivating the surgical instrument based at least partly on the haptic feedback signals.

摘要翻译： 本发明涉及一种手术系统。 在一个实施例中，系统包括可操作地响应于操作场的物理边界限制的一个或多个传感器。 此外，一个或多个传感器提供关于操作区域的物理边界限制的信息。 在另一个实施例中，系统包括被配置为通过激活或失活响应信息的外科器械。 在另一方面，本发明包括生成解剖图像或解剖学位置参考数据。 另外，该方法包括至少部分地基于解剖图像或解剖学位置参考数据创建触觉反馈信号，以及确定外科器械的位置或取向。 此外，该方法包括至少部分地基于触觉反馈信号来激活或失活外科器械。

公开(公告)号：US20080253528A1

公开(公告)日：2008-10-16

申请号：US12011641

申请日：2008-01-28

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood ,  Victoria Y.H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood ,  Victoria Y.H. Wood

IPC分类号： G01N23/201 ,  A61B18/06 ,  A61B18/08 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

CPC分类号： A61B6/483 ,  A61B6/12 ,  A61B6/145 ,  A61B6/482 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B6/548 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

摘要： One aspect relates to ablating an at least some matter of an at least a portion of an individual within an at least one prescribed desired ablating region at least partially responsive to at least some Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual that is performed at least partially through a substantial depth through the at least some matter of the at least the portion of the individual. Certain aspects can include locating an at least one prescribed desired ablating region within the at least some matter of the at least the portion of the individual at least partially responsive to the Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual.

摘要翻译： 一个方面涉及至少部分地响应于至少一些康普顿X射线散射可视化，成像或信息提供内的至少一个规定的期望的烧蚀区域内的至少一部分个体的消融。 所述个体的至少一部分的至少一部分至少部分地通过穿过个体的至少一部分的至少一些物质的相当深度进行。 某些方面可以包括至少部分地响应于康普顿X射线散射可视化，成像或至少在该至少一个内部提供的信息中定位至少一个规定的期望的消融区域至少在该个体的至少一部分物质内 至少部分个人的一些事情。

公开(公告)号：US20080035156A1

公开(公告)日：2008-02-14

申请号：US11503489

申请日：2006-08-10

申请人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  John D. Rinaldo ,  Michael A. Smith ,  Clarence T. Tegreene ,  Lowell L. Wood ,  Victoria Y.H. Wood

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K.Y. Jung ,  Eric C. Leuthardt ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  John D. Rinaldo ,  Michael A. Smith ,  Clarence T. Tegreene ,  Lowell L. Wood ,  Victoria Y.H. Wood

IPC分类号： A61G15/00

CPC分类号： A61F5/05 ,  A61G5/1043 ,  A61G7/05707 ,  A61G7/0573 ,  A61G13/121 ,  A61G13/1235 ,  A61G13/1245 ,  A61G13/1255 ,  A61G2200/34 ,  A61G2203/34

摘要： One aspect relates to reducing a pressure differential across one or more supporting surfaces of a body surface of an individual at least partially by displacing at least one displaceable contouring unit to at least partially conform to one or more contours of the body surface of the individual. Certain aspects can relate to stabilizing at least the one or more supporting surfaces of the body surface of the individual at least partially with at least one of the at least one displaceable contouring unit Other aspects can relate to relatively displacing at least one displaceable contouring unit with respect to a medical device portion based at least in part on a contour of an individual to support at least a portion of the individual while limiting pressure applied to the individual.