公开(公告)号：US07596406B2

公开(公告)日：2009-09-29

申请号：US11347549

申请日：2006-02-03

Applicant: Jan Boese ,  Martin Kleen ,  Norbert Rahn

Inventor： Jan Boese ,  Martin Kleen ,  Norbert Rahn

IPC: A61B5/44

CPC classification number: A61B5/044 ,  A61B5/0422

Abstract: Device for recording electrophysiological signals and for displaying the signals or signal information elements which are derived therefrom, comprising a catheter which includes a plurality of electrodes arranged in a distributed manner for signal recording and a rendition device for displaying the signals or the individual signal information elements which relate to the respective electrodes and are derived from the signals, wherein the signals or the signal information elements can be displayed in a display which is modeled on the geometric arrangement of the electrodes at the catheter or on the geometric arrangement of the electrodes during the signal recording.

Abstract translation: 用于记录电生理信号并用于显示由其导出的信号或信号信息元素的装置，包括导管，该导管包括以分布式布置用于信号记录的多个电极，以及用于显示信号或各个信号信息元素的再现装置 其涉及各个电极并且从信号导出，其中信号或信号信息元素可以显示在显示器中，该显示器被建模在导管处的电极的几何排列上或在电极的几何排列期间 信号记录。

公开(公告)号：US20080119901A1

公开(公告)日：2008-05-22

申请号：US11600976

申请日：2006-11-17

Applicant: Norbert Rahn ,  Jan Boese

Inventor： Norbert Rahn ,  Jan Boese

IPC: A61N1/00

CPC classification number: A61N1/056 ,  A61N2001/0585

Abstract: In a method and system for patient-specific production of a cardiac electrode, such as for use in a biventricular pacing system, a 3D representation of the coronary sinus vessel tree is segmented to indicate the interior surface thereof an a representative line from an opening of the coronary sinus vessel tree to an implantation site for the electrode, and a computerized model of the electrode is generated. A computerized virtual implantation of the electrode through the 3D representation of the coronary sinus vessel tree is implemented using the model and the internal surface and the representative line. From the virtual implantation, a determination is made as to whether an electrode conforming to the model can be guided to and implanted at the implantation site in a medically acceptable manner. If so, an actual electrode conforming to the model is then produced. If not, the model generation and the virtual implantation are iteratively modified until a satisfactory implantation result is achieved according to the virtual implantation.

Abstract translation: 在用于患者特异性生产心脏电极的方法和系统中，例如用于双心室起搏系统中，冠状窦血管树的3D表示被分割以指示其内表面与来自开口的代表性线 将冠状窦血管树移植到电极的植入部位，生成电极的电脑模型。 通过冠状窦血管树的3D表示，通过模型和内表面和代表线来实现电极的电脑虚拟植入。 从虚拟植入中，确定符合模型的电极是否可以以医学上可接受的方式被引导到植入部位并植入。 如果是这样，则产生符合该模型的实际电极。 如果不是，则模型生成和虚拟植入被迭代地修改，直到根据虚拟植入实现令人满意的植入结果。

公开(公告)号：US20080064974A1

公开(公告)日：2008-03-13

申请号：US11900834

申请日：2007-09-13

Applicant: Jan Boese ,  Andreas Meyer ,  Norbert Rahn

Inventor： Jan Boese ,  Andreas Meyer ,  Norbert Rahn

IPC: A61B5/0402

CPC classification number: A61B6/541 ,  A61B5/0402 ,  A61B6/4441

Abstract: The invention relates to a method and a medical imaging system for acquisition of image data of the heart using a medical imaging procedure during an intervention on the heart, while the heart is stimulated by a pacing signal from an external heart pacemaker, the acquisition and/or reconstruction of the image data being controlled, in particular triggered, by the pacing signal.

Abstract translation: 本发明涉及一种用于在心脏介入期间使用医学成像程序获取心脏的图像数据的方法和医学成像系统，同时心脏由来自外部心脏起搏器的起搏信号刺激，采集和/ 或通过起搏信号来重构被特别触发的图像数据。

公开(公告)号：US20080038197A1

公开(公告)日：2008-02-14

申请号：US11890400

申请日：2007-08-06

Applicant: Matthias John ,  Stefan Lautenschlager ,  Norbert Rahn

Inventor： Matthias John ,  Stefan Lautenschlager ,  Norbert Rahn

IPC: A61K49/00 ,  A61B5/05

CPC classification number: A61B6/504 ,  A61B5/0275 ,  A61B6/032 ,  A61B6/481 ,  A61B6/503 ,  A61B6/507

Abstract: The invention relates to a method for differentially representing myocardial tissue in different states of damage, comprising the following steps: administering a myocardium-suitable contrast agent to a patient under examination; entering at least one patient-specific parameter affecting the speed of uptake by and elimination from the myocardium of said contrast agent; calculating a point in time after administration of the contrast agent at which a difference between a contrast agent content in necrotic myocardial tissue and a contrast agent content in non-necrotic myocardial tissue attains a maximum value, on the basis of the at least one patient-specific parameter, and carrying out, at the point in time calculated, a late-phase CT scan for accentuation of necrotic myocardial tissue compared to non-necrotic myocardial tissue. The invention likewise relates to apparatus, in particular for carrying out the method. A clean copy of the abstract that incorporates the above amendments is provided herewith on a separate page.

Abstract translation: 本发明涉及用于差异代表不同损伤状态的心肌组织的方法，包括以下步骤：向被检查的患者施用适合心肌的造影剂; 输入至少一个影响所述造影剂的心肌的摄取速度和消除速度的患者特异性参数; 计算施用造影剂之后的时间点，其中所述造影剂中的坏死心肌组织中的造影剂含量与非坏死性心肌组织中的造影剂含量之间的差异达到最大值，基于至少一个患者 - 具体参数，并且在计算的时间点进行与非坏死心肌组织相比的坏死心肌组织的晚期CT扫描。 本发明同样涉及装置，特别是用于实施该方法。 包含上述修订的摘要的干净的副本将提供在单独的页面上。

公开(公告)号：US20070287902A1

公开(公告)日：2007-12-13

申请号：US10569957

申请日：2004-08-24

Applicant: Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

Inventor： Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

IPC: A61B18/14

CPC classification number: A61B6/032 ,  A61B5/055 ,  A61B5/7285 ,  A61B6/541 ,  A61B8/14 ,  A61B8/543 ,  A61B18/1492 ,  A61B2018/00375 ,  A61B2018/00839 ,  G01R33/5608

Abstract: The invention relates to a device and to a method for visual assistance during the electrophysiological use of a catheter in the heart, enabling electroanatomic 3D mapping data relating to an area of the heart to be treated to be visualised during the use of the catheter. Before the catheter is used, 3D image data of a body region containing the area to be treated is detected by means of a method for tomographic 3D imaging. The area to be treated or significant parts thereof are extracted from said 3D image data, in order to obtain selected 3D image data. The electroanatomic 3D mapping data and the selected 3D image data obtained are then classed in terms of position and dimension, and are adjacently visualised, for example, during the catheter ablation. The inventive method and associated device enable the orientation of the operator to be improved during the use of a catheter in the heart.

Abstract translation: 本发明涉及一种用于在心脏中电生理使用导管期间的视觉辅助的装置和方法，使得在使用导管期间能够使待处理的心脏区域的电解剖3D图映射数据被可视化。 在使用导管之前，通过用于断层3D成像的方法来检测包含待处理区域的身体区域的3D图像数据。 从所述3D图像数据中提取要处理的区域或其重要部分，以便获得所选择的3D图像数据。 然后根据位置和尺寸对所获得的电解剖3D图像数据和所选择的3D图像数据进行分类，并且例如在导管消融期间相邻地可视化。 本发明的方法和相关装置使得在使用心脏中的导管时能够改善操作者的取向。

公开(公告)号：US20070238964A1

公开(公告)日：2007-10-11

申请号：US11725377

申请日：2007-03-19

Applicant: Matthias John ,  Norbert Rahn

Inventor： Matthias John ,  Norbert Rahn

IPC: A61B5/05

CPC classification number: A61B6/032 ,  A61B8/12 ,  A61B8/5238 ,  G06T11/008

Abstract: The invention relates to a method and a device for locally-resolved visualization of the reconstruction quality, especially of the coverage of a target volume to be recorded as an image and reproduced in a three-dimensional reconstruction volume presentation, especially in the human body, by two-dimensional and/or three-dimensional images covering subareas of the volume recorded by a recording device arranged inside the target volume, with which the three-dimensional reconstruction volume presentation is created, with the subareas of the target volume covered by the individual images being determined and a visual locally-resolved presentation of the reconstruction quality, especially of the coverage, being created and output as a function of the subarea coverage.

Abstract translation: 本发明涉及一种用于本地解析的重建质量可视化的方法和装置，特别是要被记录为图像并在三维重建体积呈现中特别是在人体中再现的目标体积的覆盖范围， 通过覆盖由配置在目标体积内的记录装置记录的体积的二维和/或三维图像，三维重建体积呈现被创建，其中目标体积的子区域由个体覆盖 图像被确定，并且重建质量，特别是覆盖范围的视觉局部解决呈现被创建并作为子区域覆盖的函数而被输出。

公开(公告)号：US20070083108A1

公开(公告)日：2007-04-12

申请号：US11524611

申请日：2006-09-21

Applicant: Jan Boese ,  Norbert Rahn

Inventor： Jan Boese ,  Norbert Rahn

IPC: G01N23/04 ,  A61B5/05

CPC classification number: A61B6/12 ,  A61B5/7285 ,  A61B6/541 ,  A61B8/543 ,  A61B34/20 ,  A61B90/36 ,  A61B2017/00243 ,  A61B2090/376

Abstract: To visually support a catheter ablation in the heart, three-dimensional image data have been used prior to the intervention. During ablation, the position of the catheter is pinpointed by an orientation system. The orientation system acquires electroanatomical 3D mapping data. the two-dimensional image data is assigned to the 3D mapping data in the correct position and dimensions which is a time-consuming step. The invention makes provision for the orientation system being in a fixed location relative to the X-ray system so that a positionally and dimensionally correct alignment of the X-ray image data set with the 3D mapping data is no longer required. An image or surface based 3D-3D alignment of the three-dimensional data acquired prior to the intervention with the three-dimensional X-ray image data is considerably less time-consuming than alignment thereof with the 3D mapping data and is more reliable because more structures is recognized in the three-dimensional X-ray image data.

Abstract translation: 为了可视地支持心脏中的导管消融，在干预之前已经使用三维图像数据。 在消融期间，导管的位置由定位系统精确定位。 取向系统获取电解剖3D绘图数据。 将二维图像数据分配给三维映射数据，该数据是正确的位置和尺寸，这是耗时的步骤。 本发明提供了相对于X射线系统的定位系统在固定位置的设置，使得不再需要X射线图像数据集与3D映射数据的位置和尺寸校正对准。 在三维X射线图像数据的干预之前获取的三维数据的图像或基于表面的3D-3D对准与3D映射数据的对准相比，耗时更少，并且更可靠，因为更多 在三维X射线图像数据中识别结构。

公开(公告)号：US20070066899A1

公开(公告)日：2007-03-22

申请号：US11526177

申请日：2006-09-22

Applicant: Jan Boese ,  Norbert Rahn

Inventor： Jan Boese ,  Norbert Rahn

IPC: A61B8/00 ,  A61B18/18

CPC classification number: A61B18/1492 ,  A61B8/12 ,  A61B2017/00119 ,  A61B2017/00123 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2090/376 ,  A61B2090/378

Abstract: Medical treatment device with an ablation catheter and a visualization device for joint display of the ablation catheter and the anatomy of a part of a patient's body to be treated, whereby the visualization device is embodied for detection of areas of risk of the part of the body to be treated and for displaying the areas of risk jointly with the ablation catheter and the anatomy.

Abstract translation: 具有消融导管和用于联合显示消融导管和待治疗的患者身体的一部分的解剖结构的可视化装置的医疗处理装置，由此可视化装置被实施用于检测身体部分的风险区域 被治疗并与消融导管和解剖结构联合显示风险区域。

公开(公告)号：US20070003017A1

公开(公告)日：2007-01-04

申请号：US11478464

申请日：2006-06-29

Applicant: Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

Inventor： Jan Boese ,  Norbert Rahn ,  Bernhard Sandkamp

IPC: H05G1/58 ,  H05G1/54 ,  G01N23/04

CPC classification number: A61B6/12 ,  A61B6/06 ,  A61B6/4441 ,  A61B6/542 ,  A61B6/545

Abstract: With a method for generating an x-ray image sequence for supporting an intervention on a patient with a catheter or guide wire for instance, automatic recognition of the catheter is carried out with recorded x-ray images using a computer system. The x-ray image recording parameters are changed on the basis of the determined quality of the imaging of the object, with the x-ray device preferably being automatically activated with the changed x-ray image recording parameters, to record x-ray images. The doctor can therefore concentrate on the actual intervention and does not have to worry about operating the x-ray device.

Abstract translation: 通过使用例如用导管或引导线产生用于支持对患者的介入的X射线图像序列的方法，使用计算机系统用记录的X射线图像进行导管的自动识别。 基于所确定的物体的成像质量来改变X射线图像记录参数，其中X射线装置优选地通过改变的X射线图像记录参数被自动激活，以记录x射线图像。 因此，医生可以专注于实际的干预，而不必担心操作x射线装置。

公开(公告)号：US20060262970A1

公开(公告)日：2006-11-23

申请号：US11437089

申请日：2006-05-19

Applicant: Jan Boese ,  Norbert Rahn

Inventor： Jan Boese ,  Norbert Rahn

IPC: G06K9/00 ,  G06K9/32

CPC classification number: G03B42/023 ,  G06T7/33 ,  G06T7/38 ,  G06T2207/30048 ,  G06T2207/30101 ,  Y10S128/922

Abstract: The invention relates to a method and a device for registering 2D projection images of an object relative to a 3D image data record of the same object, in which, from just a few 2D projection images, a 3D feature contained in an object, which is also identifiable in the 3D images, is symbolically reconstructed. The 3D feature obtained in this way is then registered by 3D-3D registration with the 3D image data record.

Abstract translation: 本发明涉及一种用于相对于相同对象的3D图像数据记录来登记对象的2D投影图像的方法和装置，其中，从仅几个2D投影图像中包含在对象中的3D特征 也可以在3D图像中识别，被象征性重建。 然后通过3D-3D登记与3D图像数据记录来注册以这种方式获得的3D特征。