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公开(公告)号：US09052442B2
公开(公告)日：2015-06-09
申请号：US11978336
申请日：2007-10-29
CPC分类号： G02B1/10 , A61L12/04 , A61L12/14 , B29D11/00038 , B29D11/00865 , C08J7/04 , C08J2383/00 , G02B1/043 , G02C7/04
摘要： The invention provides a cost-effective and in-situ method for applying an LbL coating onto a silicone hydrogel contact lens directly in a lens package. The resultant silicone hydrogel contact lens has a coating with good hydrophilicity, intactness and durability and also can be used directly from the lens package by a patient without washing and/or rising. In addition, the invention provides a packaging solution for in-situ coating of a silicone hydrogel contact lens in a lens package and an ophthalmic lens product.
摘要翻译： 本发明提供了一种成本有效和原位的方法，用于将LbL涂层直接应用于透镜包装中的硅酮水凝胶隐形眼镜上。 所得的硅酮水凝胶隐形眼镜具有良好的亲水性，完整性和耐久性的涂层，并且也可以由患者直接从镜片包装中使用而无需洗涤和/或上升。 此外，本发明提供了一种用于在镜片包装和眼用透镜产品中原位涂覆硅酮水凝胶隐形眼镜的包装溶液。
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公开(公告)号：US08324256B2
公开(公告)日：2012-12-04
申请号：US12640019
申请日：2009-12-17
IPC分类号： A61K31/41 , C07D249/20
CPC分类号： C07D249/20 , G02B1/043
摘要： Described herein are tri-functional compounds useful in the production of ophthalmic lenses. The compounds are composed of UV absorber having a polymerization initiator directly or indirectly bonded to the ultraviolet absorber, and an olefinic group directly or indirectly bonded to the ultraviolet absorber. Also described herein are polymers and ophthalmic lenses produced from the tri-functional compounds described herein.
摘要翻译： 本文描述了可用于制造眼科镜片的三官能化合物。 该化合物由具有与紫外线吸收剂直接或间接结合的聚合引发剂的紫外线吸收剂以及与紫外线吸收剂直接或间接接合的烯属基团构成。 本文还描述了由本文所述的三官能化合物制备的聚合物和眼用透镜。
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公开(公告)号：US20100276824A1
公开(公告)日：2010-11-04
申请号：US12834998
申请日：2010-07-13
摘要： The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.
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公开(公告)号：US20100140114A1
公开(公告)日：2010-06-10
申请号：US12629913
申请日：2009-12-03
CPC分类号： B29D11/00067 , A61K9/0051 , G02B1/043 , C08L51/085
摘要： The invention relates to a soft hydrogel contact lens, especially a silicone hydrogel contact lens, which has a capability of delivering a hydrophobic comfort agent into the eye of a wearer. The hydrophobic comfort agent includes without limitation a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, a phospholipid, a fatty acid, a fatty alcohol, a hydrocarbon having a C12-C28 chain in length, a mineral oil, a silicone oil, or a mixture thereof. It can be released from the soft hydrogel contact lens into the eye of a wearer when being worn so as to strengthen and stabilize the tear film lipid layer and alleviate the dryness of the eye.
摘要翻译： 本发明涉及一种柔软的水凝胶隐形眼镜，特别是硅酮水凝胶隐形眼镜，其具有将疏水舒适剂输送到穿戴者的眼睛中的能力。 疏水性舒适剂包括但不限于单甘油酯，甘油二酯，甘油三酯，糖脂，甘油糖脂，鞘脂，鞘糖脂，磷脂，脂肪酸，脂肪醇，具有C12-C28链的烃 长度，矿物油，硅油或其混合物。 当穿着时，它可以从软水凝胶隐形眼镜释放到穿戴者的眼睛中，以加强和稳定泪膜脂质层并减轻眼睛的干燥。
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公开(公告)号：US10155349B2
公开(公告)日：2018-12-18
申请号：US12629913
申请日：2009-12-03
摘要： The invention relates to a soft hydrogel contact lens, especially a silicone hydrogel contact lens, which has a capability of delivering a hydrophobic comfort agent into the eye of a wearer. The hydrophobic comfort agent includes without limitation a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, a phospholipid, a fatty acid, a fatty alcohol, a hydrocarbon having a C12-C28 chain in length, a mineral oil, a silicone oil, or a mixture thereof. It can be released from the soft hydrogel contact lens into the eye of a wearer when being worn so as to strengthen and stabilize the tear film lipid layer and alleviate the dryness of the eye.
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66.发明授权Methods for making silicone hydrogel lenses from water-based lens formulations 有权从水性镜片制剂制造硅酮水凝胶镜片的方法公开(公告)号：US09005492B2
公开(公告)日：2015-04-14
申请号：US12963685
申请日：2010-12-09
申请人： Frank Chang , Lynn Cook Winterton
发明人： Frank Chang , Lynn Cook Winterton
CPC分类号： G02B1/043 , B29D11/00038 , B29D11/00048 , C08L83/04 , C08L101/14
摘要： Described herein are methods for producing silicone hydrogel lenses. The methods involve introducing into a mold a water-based lens-forming composition, curing the lens-forming composition in a mold to form the lens, and removing the lens from the mold. The lens-forming composition comprises (i) a polysiloxane-containing vinylic monomer or macromer, (ii) at least one hydrophilic vinylic monomer, (iii) a surfactant, and, and (iv) water. The surfactant is polysiloxane-containing surfactant that is free of actinically-polymerizable groups and is a copolymer having from about 10% to about 40% by weight of one or more polysiloxane segments and from about 90% to about 60% by weight hydrophilic units and/or segments. The methods permit the use of water as a solvent and reduce the need for organic solvents. Additionally, the lenses produced by the methods can have improved properties such oxygen permeability.
摘要翻译： 本文描述了生产硅酮水凝胶透镜的方法。 所述方法包括向模具中引入基于水的透镜形成组合物，在模具中固化透镜形成组合物以形成透镜，以及从模具中去除透镜。 透镜形成组合物包含（i）含聚硅氧烷的乙烯基单体或大分子单体，（ii）至少一种亲水乙烯基单体，（iii）表面活性剂和（iv）水。 表面活性剂是不含可光化聚合基团的含聚硅氧烷的表面活性剂，并且是具有约10％至约40％重量的一种或多种聚硅氧烷链段和约90％至约60％重量的亲水单元的共聚物，以及 /或段。 该方法允许使用水作为溶剂并减少对有机溶剂的需要。 另外，通过该方法制造的透镜可以具有改善的这种透氧性。
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67.发明授权公开(公告)号：US08757367B2
公开(公告)日：2014-06-24
申请号：US13328223
申请日：2011-12-16
申请人： Lynn Cook Winterton , Jack C. White
发明人： Lynn Cook Winterton , Jack C. White
IPC分类号： A45C11/04
CPC分类号： A45C11/005
摘要： A lens care system and method for venting gas to release pressure from a container, such as generated in peroxide-based lens treatment. A seal formed between a deformable cap and a container cup prevents release of liquid, but deformation of the cap under the influence of pressure generated within the container temporarily releases the seal to permit venting of gas.
摘要翻译： 用于排出气体以从容器释放压力的镜片护理系统和方法，例如在基于过氧化物的镜片处理中产生的。 形成在可变形帽和容器杯之间的密封件防止液体的释放，但是在容器内产生的压力的影响下，帽的变形暂时释放密封件以允许排气。
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68.发明申请公开(公告)号：US20120152284A1
公开(公告)日：2012-06-21
申请号：US13328223
申请日：2011-12-16
申请人： Lynn Cook Winterton , Jack C. White
发明人： Lynn Cook Winterton , Jack C. White
CPC分类号： A45C11/005
摘要： A lens care system and method for venting gas to release pressure from a container, such as generated in peroxide-based lens treatment. A seal formed between a deformable cap and a container cup prevents release of liquid, but deformation of the cap under the influence of pressure generated within the container temporarily releases the seal to permit venting of gas.
摘要翻译： 用于排出气体以从容器释放压力的镜片护理系统和方法，例如在基于过氧化物的镜片处理中产生的。 形成在可变形帽和容器杯之间的密封件防止液体的释放，但是在容器内产生的压力的影响下，帽的变形暂时释放密封件以允许排气。
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公开(公告)号：US08092724B2
公开(公告)日：2012-01-10
申请号：US12834979
申请日：2010-07-13
摘要： The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.
摘要翻译： 本发明涉及一种用于制造具有改善的镜片质量和增加的产品产量的隐形眼镜的方法和流体组合物。 本发明的方法包括将磷脂添加到包含透镜形成材料的流体组合物中，其量足以将平均的模具分离力与没有磷脂的模具分离力相比降低至少约40％。
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公开(公告)号：US07858000B2
公开(公告)日：2010-12-28
申请号：US11810601
申请日：2007-06-06
申请人： Lynn Cook Winterton
发明人： Lynn Cook Winterton
IPC分类号： B29D11/00
CPC分类号： B29D11/00865 , B29D11/00076 , G02B1/043
摘要： The invention provides a cost-effective method for making a silicone hydrogel contact lens which has a good wettable coating with a good durability.
摘要翻译： 本发明提供了一种制造具有良好耐久性的良好可湿性涂层的硅酮水凝胶隐形眼镜的成本有效的方法。
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