Method and kits for sterilizing and storing soft contact lenses
    3.
    发明授权
    Method and kits for sterilizing and storing soft contact lenses 有权
    消毒和存放软性隐形眼镜的方法和试剂盒

    公开(公告)号:US07722808B2

    公开(公告)日:2010-05-25

    申请号:US10936032

    申请日:2004-09-08

    IPC分类号: A61L2/00

    CPC分类号: A61L12/04 A45C11/005

    摘要: The present invention provides a method and a container for sterilizing a soft contact lens and for providing a sterilized storage package of the soft contact lens maintained in a packaging solution. By using the method and container of the invention, deformations of soft contact lenses during autoclave can be substantially reduced.

    摘要翻译: 本发明提供一种消毒软性隐形眼镜的方法和容器,以及提供保持在包装溶液中的软性隐形眼镜的消毒储存包装。 通过使用本发明的方法和容器,可以显着减少高压釜中软性隐形眼镜的变形。

    Packaging Solutions
    4.
    发明申请
    Packaging Solutions 有权
    包装解决方案

    公开(公告)号:US20090173044A1

    公开(公告)日:2009-07-09

    申请号:US12258916

    申请日:2008-10-27

    IPC分类号: B65B55/02

    摘要: Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a substantially water-soluble silicone-containing surfactant. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity.

    摘要翻译: 公开了用于存储诸如隐形眼镜的眼科装置的包装系统,以及用于包装这些眼科装置的方法以提供穿戴期间镜片的舒适度的解决方案。 包装系统包括存储在包含基本上水溶性的含硅氧烷表面活性剂的水性包装溶液中的眼科装置。 这种溶液长时间保留在未使用的镜片的表面上,导致眼睛中持续存在的表面改性,这可以显着改善首次使用的新鲜隐形眼镜的润湿性能,此外甚至 镜片插入后数小时,防止干燥,提高润滑性。

    Method for sterilization of hydrogel contact lenses
    5.
    发明申请
    Method for sterilization of hydrogel contact lenses 有权
    水凝胶隐形眼镜灭菌方法

    公开(公告)号:US20080317625A1

    公开(公告)日:2008-12-25

    申请号:US12229111

    申请日:2008-08-20

    IPC分类号: A61L12/04 C09K3/00 A45C11/04

    摘要: The present invention provides an aqueous solution for sterilizing and storing ophthalmic devices, preferably a contact lens, made of a hydrogel material, preferably a poly(oxyalkylene)-containing hydrogel material. The solution comprises one or more organic buffer agents, such as a Good buffer or a bis-aminopolyols; an organic tonicity-adjusting agent with multiple hydroxyl groups in an amount sufficient to provide an osmolarity of from about 200 to about 450 mosm/l, wherein the aqueous solution has a pH of from about 5.5 to about 8.5, provided that the aqueous solution include phosphate buffer at a concentration of about 15 mM or less and about 5000 ppm sodium chloride. The present invention also provides a method for sterilizing and storing an ophthalmic device using an aqueous solution of the invention.

    摘要翻译: 本发明提供一种水溶液,用于消毒和储存由水凝胶材料,优选含有(含氧化烯)的水凝胶材料制成的眼科装置,优选隐形眼镜。 溶液包含一种或多种有机缓冲剂,例如Good缓冲液或双 - 氨基多元醇; 具有多个羟基的有机张力调节剂,其量足以提供约200至约450 mosm / l的渗透压,其中所述水溶液的pH为约5.5至约8.5,条件是所述水溶液包括 浓度为约15mM或更低和约5000ppm氯化钠的磷酸盐缓冲液。 本发明还提供使用本发明的水溶液对眼科装置进行消毒和储存的方法。

    Contact Lens Package Solution
    6.
    发明申请
    Contact Lens Package Solution 审中-公开
    隐形眼镜包解决方案

    公开(公告)号:US20080307751A1

    公开(公告)日:2008-12-18

    申请号:US11664620

    申请日:2005-09-30

    IPC分类号: B65B55/02 C11D1/00 A45C11/04

    摘要: An aqueous contact lens storage solution comprises a viscoelastic rheology modifier; and not more than 0.3% w/v of an alkali metal salt; the solution has a pH of between 6.0 and 8.0 and an osmolality of between 100 and 400 mOsm/kg, and the solution has viscoelastic properties, even if heat sterilized at 121° C. for at least 15 minutes. The viscoelastic rheology modifier may be selected from the following acids or their alkali metal salts: hyaluronic acid, poly (acrylic acid), crosslinked poly (acrylic acid), poly (methacrylic acid), carboxymethyl cellulose, alginic acid and mixtures thereof. The alkali metal salt may be present in an amount of from 0.01% to 0.3% w/v, and be selected from sodium chloride, sodium bicarbonate, sodium dihydrogen phosphate, disodium hydrogen phosphate, trisodium phosphate, sodium tetraborate, sodium citrate, sodium acetate, sodium lactate, potassium chloride, potassium bicarbonate, potassium dihydrogen phosphate, dipotassium hydrogen phosphate, tripotassium phosphate, potassium tetraborate, potassium citrate, potassium acetate, potassium lactate and mixtures thereof. The solution may be an inhomogeneous combination of a gel component and an additional liquid component. If so, the solution has a pH of between 6.0 and 8.0 and an osmolality of between 100 and 400 mOsm/kg when in a homogeneous form.

    摘要翻译: 水溶性隐形眼镜储存溶液包含粘弹性流变改性剂; 和不超过0.3%w / v的碱金属盐; 该溶液具有6.0至8.0的渗透压和100至400mOsm / kg的渗透压,并且该溶液具有粘弹性,即使在121℃热灭菌至少15分钟。 粘弹性流变改性剂可以选自以下酸或其碱金属盐:透明质酸,聚(丙烯酸),交联聚(丙烯酸),聚(甲基丙烯酸),羧甲基纤维素,海藻酸及其混合物。 碱金属盐的存在量可以为0.01〜0.3%w / v,选自氯化钠,碳酸氢钠,磷酸二氢钠,磷酸氢二钠,磷酸三钠,四硼酸钠,柠檬酸钠,乙酸钠 ,乳酸钠,氯化钾,碳酸氢钾,磷酸二氢钾,磷酸氢二钾,磷酸三钾,四硼酸钾,柠檬酸钾,乙酸钾,乳酸钾及其混合物。 溶液可以是凝胶组分和另外的液体组分的不均匀组合。 如果是这样,当均匀形式时,溶液的pH值在6.0和8.0之间,重量摩尔渗透压浓度在100和400mOsm / kg之间。

    Contact Lens, Method For Producing Same, And Pack For Storage And Maintenace Of A Contact Lens
    7.
    发明申请
    Contact Lens, Method For Producing Same, And Pack For Storage And Maintenace Of A Contact Lens 有权
    隐形眼镜,用于生产相同的方法,以及用于存放和保护隐形眼镜的包装

    公开(公告)号:US20080170201A1

    公开(公告)日:2008-07-17

    申请号:US11814556

    申请日:2006-02-09

    CPC分类号: A61L12/04 A61L12/08 G02B1/043

    摘要: A contact lens (4) comprises a solid component capable of imparting shape and structure to said lens, and a liquid component, at least partially contained in the solid component, capable of favouring the compatibility between said lens and the eye of a user of said lens, wherein the liquid component comprises a solution capable of being used as a lachrymal substitute.

    摘要翻译: 隐形眼镜(4)包括能够赋予所述透镜的形状和结构的固体部件和至少部分地包含在所述固体部件中的液体组分,其能够有利于所述透镜与所述透镜的使用者的眼睛之间的相容性 透镜,其中液体组分包括能够用作泪液替代物的溶液。

    Methods for sterilizing silicone hydrogel contact lenses
    9.
    发明申请
    Methods for sterilizing silicone hydrogel contact lenses 审中-公开
    硅胶水凝胶隐形眼镜灭菌方法

    公开(公告)号:US20070104611A1

    公开(公告)日:2007-05-10

    申请号:US11595578

    申请日:2006-11-08

    IPC分类号: A61L2/00

    CPC分类号: A61L12/06 A61L12/04

    摘要: Methods of sterilizing silicone hydrogel contact lenses include exposing one or more silicone hydrogel contact lenses to high energy radiation, such as gamma radiation or electron beam radiation. Sterilized contact lens packages containing such silicone hydrogel contact lenses are also described.

    摘要翻译: 灭菌硅酮水凝胶隐形眼镜的方法包括将一种或多种硅酮水凝胶隐形眼镜暴露于高能量辐射,例如γ辐射或电子束辐射。 还描述了含有这种硅酮水凝胶隐形眼镜的灭菌隐形眼镜包装。