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公开(公告)号：US07708701B2
公开(公告)日：2010-05-04
申请号：US10323622
申请日：2002-12-18
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： A device for use in penetrating tissue to obtain a body fluid sample is provided. A cartridge may be included. A plurality of penetrating members are slidably coupled to the cartridge. Each penetrating member has a distal end that is sufficiently sharp to pierce tissue. Each penetrating member may be moveable relative to the other ones of the penetrating members so that the sharpened distal ends extend radially outward to penetrate tissue. The penetrating members are elongate members without molded attachments.
摘要翻译： 提供了用于穿透组织以获得体液样品的装置。 可以包括墨盒。 多个穿透构件可滑动地联接到盒。 每个穿透构件具有足够锋利的远端以刺穿组织。 每个穿透构件可以相对于穿透构件中的另一个移动，使得锋利的远端径向向外延伸以穿透组织。 穿透构件是没有模制附件的细长构件。
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公开(公告)号：US07648469B2
公开(公告)日：2010-01-19
申请号：US12023615
申请日：2008-01-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 μL of the fluid.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1μl流体的样品来确定流体中分析物的浓度。
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公开(公告)号：US07547287B2
公开(公告)日：2009-06-16
申请号：US10335212
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
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公开(公告)号：US07410468B2
公开(公告)日：2008-08-12
申请号：US10335182
申请日：2002-12-31
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15123 , A61B5/15146 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A skin penetrating system includes a housing member and a penetrating member positioned in the housing member. An analyte detecting member is coupled to a sample chamber. The analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 μL of a body fluid disposed in the sample chamber. A tip of the penetrating member is configured to extend through an opening of the sample chamber.
摘要翻译： 皮肤穿透系统包括壳体构件和定位在壳体构件中的穿透构件。 分析物检测部件耦合到样品室。 分析物检测构件被配置为使用设置在样品室中的小于1μl体液的样品来确定体液中的分析物的浓度。 穿透构件的尖端构造成延伸穿过样品室的开口。
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公开(公告)号：US07374544B2
公开(公告)日：2008-05-20
申请号：US10335142
申请日：2002-12-31
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. An analyte detecting member is positioned to receive fluid from a wound created by the penetrating member. The detection member is configured to determine a concentration of an analyte in the fluid using a sample of less than 1 mL of the fluid.
摘要翻译： 本发明的这些和其它目的是在包括电动驱动力发生器的组织部位上使用的体液取样系统中实现的。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 分析物检测构件定位成从由穿透构件产生的伤口接收流体。 检测构件被配置为使用小于1mL的流体的样品来确定流体中的分析物的浓度。
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公开(公告)号：US20080027385A1
公开(公告)日：2008-01-31
申请号：US11539542
申请日：2006-10-06
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , G01N27/28 , G06F19/00 , G06Q50/24
摘要： A skin penetrating system is provided with a drive force generator and a disposable housing member. A plurality of penetrating members are positioned in the disposable housing member. Each penetrating member is coupled to the drive force generator. A plurality of analyte detecting members are each associated with a penetrating member and are positioned in the disposable housing member. Each analyte detecting member is positioned in a sample chamber with a volume of less than 1 μL, The sample chambers have openings for transport of a body fluid into the sample chamber. Each analyte detecting member is configured to determine a concentration of an analyte in a body fluid using a sample of less than 1 μL of a body fluid disposed in the sample chamber. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
摘要翻译： 皮肤穿透系统设置有驱动力发生器和一次性外壳构件。 多个穿透构件定位在一次性外壳构件中。 每个穿透构件联接到驱动力发生器。 多个分析物检测构件各自与穿透构件相关联并且被定位在一次性外壳构件中。 每个分析物检测构件被定位在体积小于1μL的样品室中。样品室具有用于将体液输送到样品室中的开口。 每个分析物检测构件被配置为使用设置在样品室中的小于1μl体液的样品来确定体液中的分析物的浓度。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。
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公开(公告)号：US07244265B2
公开(公告)日：2007-07-17
申请号：US10335099
申请日：2002-12-31
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B17/14
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. The drive force generator is configured to be controlled to follow a predetermined velocity trajectory into the tissue and out of the tissue. A tissue stabilizing member is associated with the device and at least partially surrounds an impact location of the penetrating member on the tissue site. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.
摘要翻译： 本发明的这些和其它目的在体液采集系统中实现，该体液采样系统用于组织部位，其包括驱动力发生器和可操作地联接到力发生器的穿透构件。 力产生器沿着路径将构件沿着穿过构件出口的壳体移动到组织部位中，停止在组织部位中，并从组织部位抽出。 驱动力发生器被配置为被控制以遵循预定的速度轨迹进入组织并离开组织。 组织稳定构件与装置相关联并且至少部分地围绕穿刺构件在组织部位上的冲击位置。 用户界面被配置为中继穿透构件性能或穿透构件设置中的至少一种。
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68.发明授权Method and apparatus for a multi-use body fluid sampling device with analyte sensing 有权用于具有分析物感测的多用途体液采样装置的方法和装置公开(公告)号：US07198606B2
公开(公告)日：2007-04-03
申请号：US10323624
申请日：2002-12-18
申请人： Dirk Boecker , Dominique M. Freeman
发明人： Dirk Boecker , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： A device for use with a penetrating member driver to penetrate tissue is provided. A plurality of penetrating members are coupled to a single cartridge and are operatively couplable to the penetrating member driver. The penetrating members are movable to extend radially outward from the cartridge to penetrate tissue. A plurality of analyte sensors are coupled to the single cartridge and are positioned on the cartridge to receive body fluid from a wound in the tissue created by the penetrating member.
摘要翻译： 提供了一种用于穿透构件驱动器以穿透组织的装置。 多个穿透构件联接到单个盒，并且可操作地连接到穿透构件驱动器。 穿透构件可移动以从筒体径向向外延伸以穿透组织。 多个分析物传感器耦合到单个盒并且被定位在盒上以从穿透构件产生的组织中的伤口接收体液。
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69.发明授权公开(公告)号：US07141058B2
公开(公告)日：2006-11-28
申请号：US10423851
申请日：2003-04-24
IPC分类号： A61B5/00
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/14551 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150755 , A61B5/150824 , A61B5/15113 , A61B5/15123 , A61B5/15151 , A61B5/15161 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15182 , A61B17/8863 , Y10S436/808
摘要： A body fluid sampling device for extracting bodily fluid from an anatomical feature is provided. The device comprises a penetrating member driver for driving a penetrating member to create a wound to extract bodily fluid; a light source positioned to indicate a point of sampling where the wound will be created, the light source indicating the point of sampling with a beam of light. The light source may be selected from one of the following: an LED, incandescent, fluorescent, or electroluminescent light source.
摘要翻译： 提供一种用于从解剖特征提取体液的体液取样装置。 该装置包括用于驱动穿透构件以产生伤口以提取体液的穿透构件驱动器; 定位成指示将创建伤口的采样点的光源，光源指示用光束采样点。 光源可以选自以下之一：LED，白炽灯，荧光灯或电致发光光源。
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公开(公告)号：US07001344B2
公开(公告)日：2006-02-21
申请号：US10173236
申请日：2002-06-12
IPC分类号： A61B5/00
CPC分类号： A61B5/15142 , A61B5/150022 , A61B5/150099 , A61B5/150221 , A61B5/150412 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150824 , A61B5/150832 , A61B5/15109 , A61B5/15121 , A61B5/15123 , A61B5/15125 , A61B5/15144
摘要： A device and method to obtain a blood sample in a sealed configuration. The device includes a sampling assembly having a driver, a lancet, and a blood reservoir, and a pad having a proximal side and a distal side. The proximal side of the pad conforms to the shape of a skin area, and the distal side is attached to the sampling assembly. The pad and the sampling assembly are configured to provide a sealed configuration around the skin area for transferring blood from the skin area to the blood reservoir.
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