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116 条记录 (耗时 0.06 秒)

    Bonding sleeve for a medical device
    62.
    发明授权
    Bonding sleeve for a medical device 有权
    用于医疗器械的接合套管

    公开(公告)号：US08690905B2

    公开(公告)日：2014-04-08

    申请号：US12872882

    申请日：2010-08-31

    申请人： Matthew C. Heidner ,  Thomas J. Holman

    发明人： Matthew C. Heidner ,  Thomas J. Holman

    IPC分类号： A61M29/00

    CPC分类号： A61F2/958 ,  A61F2002/9583

    摘要： A medical device delivery system comprises an inner tube, a medical device disposed about a portion of the distal region of the inner tube, a medical device sheath disposed about the medical device, a medical device sheath retraction device extending proximally from the medical device sheath and an outer sheath disposed about a portion of the medical device sheath retraction device. The distal end of the outer sheath terminates at least one medical device length proximal of the medical device. The medical device sheath is movable relative to the outer sheath and relative to the inner tube.

    摘要翻译： 医疗装置输送系统包括内管，围绕内管的远端区域的一部分设置的医疗装置，围绕医疗装置设置的医疗装置护套，从医疗装置护套向近侧延伸的医疗装置护套收回装置， 设置在所述医疗装置鞘缩回装置的一部分周围的外护套。 外护套的远端终止医疗装置近端的至少一个医疗装置长度。 医疗器械护套可相对于外护套和相对于内管移动。

    Mechanism for adjacent-symbol error correction and detection
    63.
    发明授权
    Mechanism for adjacent-symbol error correction and detection 有权
    相邻符号纠错和检测机制

    公开(公告)号：US08327222B2

    公开(公告)日：2012-12-04

    申请号：US12354037

    申请日：2009-01-15

    申请人： James W. Alexander ,  Thomas J. Holman ,  Mark A. Heap ,  Stanley S. Kulick

    发明人： James W. Alexander ,  Thomas J. Holman ,  Mark A. Heap ,  Stanley S. Kulick

    IPC分类号： G11C29/00

    CPC分类号： G11C29/42 ,  G11C11/401 ,  G11C2029/0409

    摘要： According to one embodiment a computer system is disclosed. The computer system includes memory. The memory includes two or more rows, where each row has a plurality of memory devices. The computer system also includes a chipset. The chipset includes a detection/correction circuit to detect single and double symbol errors and correct single symbol errors for each memory row, and markers to maintain a log of errors within each memory row.

    摘要翻译： 根据一个实施例，公开了一种计算机系统。 计算机系统包括内存。 存储器包括两行或更多行，其中每行具有多个存储器件。 计算机系统还包括芯片组。 该芯片组包括一个检测/校正电路，用于检测单个和双重符号错误，并纠正每个存储器行的单个符号错误，以及标记以维护每个存储器行内的错误日志。

    Method and apparatus for forming a feature in a workpiece by laser ablation with a laser beam having an adjustable intensity profile to redistribute the energy density impinging on the workpiece
    64.
    发明授权
    Method and apparatus for forming a feature in a workpiece by laser ablation with a laser beam having an adjustable intensity profile to redistribute the energy density impinging on the workpiece 失效
    通过具有可调强度分布的激光束通过激光烧蚀在工件中形成特征的方法和装置，以重新分布冲击在工件上的能量密度

    公开(公告)号：US08158904B2

    公开(公告)日：2012-04-17

    申请号：US10918841

    申请日：2004-08-13

    申请人： Jan Weber ,  Thomas J. Holman

    发明人： Jan Weber ,  Thomas J. Holman

    IPC分类号： B23K26/38 ,  B23K26/06

    CPC分类号： B23K26/066 ,  B23K26/073 ,  B23K26/384 ,  B23K26/389

    摘要： A method and apparatus is provided for removing material from an outer surface of a workpiece such as a catheter or other medical device. The method begins by generating a laser beam having an intensity profile and directing the laser beam onto the outer surface of the workpiece. After the laser beam is generated, its intensity profile is adjusted by a component such as a diffractive optical element (DOE) or a holographic optical element (HOE) so that material can be removed from the workpiece by ablation in a prescribed manner.

    摘要翻译： 提供了用于从诸如导管或其它医疗装置的工件的外表面去除材料的方法和装置。 该方法通过产生具有强度分布并将激光束引导到工件的外表面上的激光束开始。 在产生激光束之后，其强度分布由诸如衍射光学元件（DOE）或全息光学元件（HOE）的部件调节，使得可以通过以规定的方式通过烧蚀从材料中去除材料。

    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
    65.
    发明授权
    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 有权
    用于与电力源一起递送治疗剂的内部医疗装置

    公开(公告)号：US08152759B2

    公开(公告)日：2012-04-10

    申请号：US12077603

    申请日：2008-03-20

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61M29/00

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。

    Method and apparatus for high reliability data storage and retrieval operations in multi-level flash cells
    68.
    发明授权
    Method and apparatus for high reliability data storage and retrieval operations in multi-level flash cells 失效
    用于多级闪存单元中高可靠性数据存储和检索操作的方法和装置

    公开(公告)号：US07941592B2

    公开(公告)日：2011-05-10

    申请号：US12228795

    申请日：2008-08-14

    申请人： Randy M. Bonella ,  Daniel J. Allen ,  Thomas J. Holman ,  Chung W. Lam ,  Hiroyuki Sakamoto

    发明人： Randy M. Bonella ,  Daniel J. Allen ,  Thomas J. Holman ,  Chung W. Lam ,  Hiroyuki Sakamoto

    IPC分类号： G06F12/00

    CPC分类号： G11C11/5628 ,  G11C2211/5641

    摘要： One or more multi-level NAND flash cells are operated so as to store only single-level data, and these operations achieve an increased level of charge separation between the data states of the single-level operation by requiring a write to both the upper and lower pages, even though only one bit of data is being stored. That is, the second write operation increases the difference in floating gate charge between the erased state and the programmed state of the first write operation without changing the data in the flash memory cell. In one embodiment, a controller instructs the flash memory to perform two write operations for storing a single bit of data in an MLC flash cell. In another embodiment, the flash memory recognizes that a single write operation is directed a high reliability memory area and internally generates the required plurality of programming steps to place at least a predetermined amount of charge on the specified floating gate.

    摘要翻译： 操作一个或多个多电平NAND闪存单元以仅存储单级数据，并且这些操作通过要求写入上层和第二级的单级操作来实现单级操作的数据状态之间的电荷分离水平的提高 即使只有一位数据被存储，也是较低的页面。 也就是说，第二写入操作增加擦除状态和第一写操作的编程状态之间的浮栅电荷的差异，而不改变闪存单元中的数据。 在一个实施例中，控制器指示闪速存储器执行用于在MLC闪存单元中存储单个数据位的两个写入操作。 在另一个实施例中，闪速存储器识别出单个写入操作被引导到高可靠性存储区域，并且在内部产生所需的多个编程步骤以将至少预定量的电荷放置在指定的浮动栅极上。

    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
    70.
    发明授权
    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 失效
    用于与电力源一起递送治疗剂的内部医疗装置

    公开(公告)号：US07850645B2

    公开(公告)日：2010-12-14

    申请号：US11055930

    申请日：2005-02-11

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61M29/00

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。